Medicine and Health Sciences Commons^™

Identifying Behavioral Differences Between People With And Without Previous Cancer Diagnosis, Kyle Anderson, Lisa Sparks, Jianwei Zhang, Cyril Rakovski

Communication Faculty Articles and Research

We undertake a study to determine and assess the effects of the statistically significant predictors of the behaviors and notions that are associated with a cancer diagnosis using the 2014 Health Information National Trends Survey (HINTS) data. We implemented a new and extensive logistic regression modeling using stepwise variable selection and jackknife parameter estimation that identified the best explanatory model. Our results show that age, average time spent watching TV or playing games, usage of sunscreen, fruit intake intent, and the opinion-based variables for behaviors affecting high blood pressure, as well as the participant preference of not knowing the chance …

Functional Reorganization During The Recovery Of Contralesional Target Selection Deficits After Prefrontal Cortex Lesions In Macaque Monkeys, Ramina Adam, Kevin Johnston, Ravi S. Menon, Stefan Everling

Brain and Mind Institute Researchers' Publications

© 2019 The Authors Visual extinction has been characterized by the failure to respond to a visual stimulus in the contralesional hemifield when presented simultaneously with an ipsilesional stimulus (Corbetta and Shulman, 2011). Unilateral damage to the macaque frontoparietal cortex commonly leads to deficits in contralesional target selection that resemble visual extinction. Recently, we showed that macaque monkeys with unilateral lesions in the caudal prefrontal cortex (PFC) exhibited contralesional target selection deficits that recovered over 2–4 months (Adam et al., 2019). Here, we investigated the longitudinal changes in functional connectivity (FC) of the frontoparietal network after a small or large …

Neural Representations Of Phonology In Temporal Cortex Scaffold Longitudinal Reading Gains In 5- To 7-Year-Old Children, Jin Wang, Marc F. Joanisse, James R. Booth

Brain and Mind Institute Researchers' Publications

© 2019 Elsevier Inc. The objective of this study was to investigate whether phonological processes measured through brain activation are crucial for the development of reading skill (i.e. scaffolding hypothesis) and/or whether learning to read words fine-tunes phonology in the brain (i.e. refinement hypothesis). We specifically looked at how different grain sizes in two brain regions implicated in phonological processing played a role in this bidirectional relation. According to the dual-stream model of speech processing and previous empirical studies, the posterior superior temporal gyrus (STG) appears to be a perceptual region associated with phonological representations, whereas the dorsal inferior frontal …

The History Of Lobotomies: Examining Its Impacts On Marginalized Groups And The Development Of Psychosurgery, Simon Godin, Brett Leblanc

Psychology from the Margins

Frontal lobotomies, which are defined as the lesioning of the frontal lobe from the rest of the brain, were performed extensively from the 1930s to the 1960s in Europe and the United States, significantly impacting psychology and psychosurgery. The history of frontal lobotomies features many different practitioners with diverse methods; however, the overwhelming majority of popular lobotomists committed unethical actions by today’s standards that led to the direct marginalization of specific demographics. Using a framework guided by an exploration of those historically disempowered by the performance of lobotomies, this review article traces the lobotomy’s historical progression, focusing on the unethical …

The Project Talent Twin And Sibling Study: Zygosity And New Data Collection, Carol A. Prescott, Ellen E. Walters, Thalida Em Arpawong, Catalina Zavala, Tara L. Gruenewald, Margaret Gatz

Psychology Faculty Articles and Research

The Project Talent Twin and Sibling (PTTS) study includes 4481 multiples and their 522 nontwin siblings from 2233 families. The sample was drawn from Project Talent, a U.S. national longitudinal study of 377,000 individuals born 1942–1946, first assessed in 1960 and representative of U.S. students in secondary school (Grades 9–12). In addition to the twins and triplets, the 1960 dataset includes 84,000 siblings from 40,000 other families. This design is both genetically informative and unique in facilitating separation of the ‘common’ environment into three sources of variation: shared by all siblings within a family, specific to twin-pairs, and associated with …

Striatum-Mediated Deficits In Stimulus-Response Learning And Decision-Making In Ocd, Nole M. Hiebert, Marc R. Lawrence, Hooman Ganjavi, Mark Watling, Adrian M. Owen, Ken N. Seergobin, Penny A. Macdonald

Brain and Mind Institute Researchers' Publications

© Copyright © 2020 Hiebert, Lawrence, Ganjavi, Watling, Owen, Seergobin and MacDonald. Obsessive compulsive disorder (OCD) is a prevalent psychiatric disorder characterized by obsessions and compulsions. Studies investigating symptomatology and cognitive deficits in OCD frequently implicate the striatum. The aim of this study was to explore striatum-mediated cognitive deficits in patients with OCD as they complete a stimulus-response learning task previously shown to differentially rely on the dorsal (DS) and ventral striatum (VS). We hypothesized that patients with OCD will show both impaired decision-making and learning, coupled with reduced task-relevant activity in DS and VS, respectively, compared to healthy controls. …

Hippocampal Subfields Revealed Through Unfolding And Unsupervised Clustering Of Laminar And Morphological Features In 3d Bigbrain, J. Dekraker, J. C. Lau, K. M. Ferko, A. R. Khan, S. Köhler

Brain and Mind Institute Researchers' Publications

© 2019 Elsevier Inc. The internal structure of the human hippocampus is challenging to map using histology or neuroimaging due to its complex archicortical folding. Here, we aimed to overcome this challenge using a unique combination of three methods. First, we leveraged a histological dataset with unprecedented 3D coverage, BigBrain. Second, we imposed a computational unfolding framework that respects the topological continuity of hippocampal subfields, which are traditionally defined by laminar composition. Third, we adapted neocortical parcellation techniques to map the hippocampus with respect to not only laminar but also morphological features. Unsupervised clustering of these features revealed subdivisions that …

Investigating The Modulatory Effect Of Expectations On Memory Retrieval During Sentence Comprehension, Luca Campanelli

Dissertations, Theses, and Capstone Projects

Memory retrieval and probabilistic expectations are recognized factors in sentence comprehension that capture two different critical aspects of processing difficulty: the cost of retrieving and integrating previously processed elements with the new input words and the cost of incorrect predictions about upcoming words or structures in a sentence. Although these two factors have independently received substantial support from the extant literature, how they interact remains poorly understood. This study investigated memory retrieval, more specifically retrieval interference, and lexical-semantic expectations in three reading experiments, pitting these factors against each other to observe how they interact. Overall, results showed that retrieving and …

The Effectiveness Of A Mindfulness-Based Intervention: A Neuropsychological Perspective Using An Electroencephalography, Elizabeth Mary Grace

Doctor of Psychology (PsyD)

In recent years, there has been a significant increase in mindfulness-related techniques. The willingness to experience emotions fully, just as they are, is a catalyst for psychological change to occur. Mindfulness has been used to alleviate stress and promote healthy living (Lagopoulos et al., 2009). The clinical utility of mindfulness has grown exponentially; however, the neuropsychological process of mindfulness is still being understood. The present study sought to examine the influence of a brief mindfulness intervention on brain activation in college students. A sample (n = 17) of undergraduate participants were randomly assigned into a prepost mindfulness intervention or control …

The 5cs Of Beating The Coronavirus Outbreak, David Chan

Research Collection School of Social Sciences

Practise being calm, cautious, considerate, caring and collectivistic. And use these tools to build up arsenal of psychological defence against the virus threat.

Positivity Can Strengthen Immunity, Sean Teck Hao Lee, Andree Hartanto

Research Collection School of Social Sciences

In the laboratories of Carnegie Mellon University some years ago, 95 men and 98 women volunteered to have live cold and flu viruses sprayed directly into their noses.

Access To Autism Spectrum Disorder Services For Rural Appalachian Citizens, Angela Scarpa, Laura S. Jensen, Denis Gracanin, Sharon L. Ramey, Angela V. Dahiya, L. Maria Ingram, Jordan Albright, Alyssa J. Gatto, Jen P. Scott, Lisa Ruble

Journal of Appalachian Health

Background: Low-resource rural communities face significant challenges regarding availability and adequacy of evidence-based services.

Purposes: With respect to accessing evidence-based services for Autism Spectrum Disorder (ASD), this brief report summarizes needs of rural citizens in the South-Central Appalachian region, an area notable for persistent health disparities.

Methods: A mixed-methods approach was used to collect quantitative and qualitative data during focus groups with 33 service providers and 15 caregivers of children with ASD in rural southwest Virginia.

Results: Results supported the barriers of availability and affordability of ASD services in this region, especially relating to the need for more ASD-trained providers, …

Barn-Raising On The Digital Frontier: The L.A.U.N.C.H. Collaborative, Bradford W. Hesse, David Ahern, Michele Ellison, Eliah Aronoff-Spencer, Robin C. Vanderpool, Karen Onyeije, Michael C. Gibbons, Timothy W. Mullett, Ming-Yuan Chih, Victoria Attencio, Grant Patterson, Jessica Boten, Christopher Hartshorn, Ben Bartolome, Katie Gorscak, Melanie Mccomsey, Alexandra Hubenko, Bin Huang, Corey Baker, Don Norman

Journal of Appalachian Health

A meta-analysis of oncology papers from around the world revealed that cancer patients who lived more than 50 miles away from hospital centers routinely presented with more advanced stages of disease at diagnosis, exhibited lower adherence to prescribed treatments, presented with poorer diagnoses, and reported a lower quality of life than patients who lived nearer to care facilities. Connected health approaches—or the use of broadband and telecommunications technologies to evaluate, diagnose, and monitor patients beyond the clinic—are becoming an indispensable tool in medicine to overcome the obstacle of distance.

Saccade Latency Provides Evidence For Reduced Face Inversion Effects With Higher Autism Traits, Robin Laycock, Kylie Wood, Andrea Wright, Sheila G. Crewther, Melvyn A. Goodale

Brain and Mind Institute Researchers' Publications

© Copyright © 2020 Laycock, Wood, Wright, Crewther and Goodale. Individuals on the autism spectrum are reported to show impairments in the processing of social information, including aspects of eye-movements towards faces. Abnormalities in basic-level visual processing are also reported. In the current study, we sought to determine if the latency of saccades made towards social targets (faces) in a natural scene as opposed to inanimate targets (cars) would be related to sub-clinical autism traits (ATs) in individuals drawn from a neurotypical population. The effect of stimulus inversion was also examined given that difficulties with processing inverted faces are thought …

Students’ Perceptions Of Justice: Application Of Sanctions, Guilt, And Responsibility In Campus Sexual Assault Cases, Diane R. Follingstad, Caihong R. Li, Jaspreet K. Chahal, Claire M. Renzetti

CRVAW Faculty Journal Articles

Despite growing attention to adjudication of campus sexual assault cases, little is known how students perceive “justice” for such cases. The present study examined whether victim, perpetrator, and assault characteristics influenced students’ perceptions of: whether a sanctionable violation occurred; the type of sanction to be applied; perceived severity of the sanction; proportion of guilt attributable to the victim and perpetrator; and level of responsibility of the victim and perpetrator. Fourteen factors pertaining to potential negative evaluation of rape victims were derived; thus, a non-factorial vignette survey design focusing only on each main effect was employed. 846 college students responded to …

Effects Of Quantitative Literacy On Healthcare Decision-Making: An Aural Context, Robert G. Root, Sonia Bhala

Numeracy

We propose a relationship between sensory modality, numerical formatting, and performance on a survey simulating healthcare decision-making. We examine the current literature on aural health literacy, and specifically aural literacy coupled with health numeracy. We then create a survey instrument called the Bhala test for this purpose and demonstrate that it is moderately internally consistent and provides results that correlate with the NUMi assessment, a widely accepted measure of health numeracy. The quantitative information provided in the Bhala test has two treatments, percentage and natural frequency formats, in an effort to determine which format is easier for subjects to use …

The Missing Moral Dimension: Perceptions Of Transgressions And The Moderating Role Of Moral Foundations On Psychological Distress, Hannah Reas

Clinical Psychology Dissertations

Anxiety and depression can be represented on a dimensional spectrum of negative affect, broadly termed psychological distress. Research has identified several factors that maintain negative emotion, but have neglected the possibility that individuals’ interpretations of moral issues in the larger macro-system affects their level of distress. Thus, the current study investigated the role of perceptions of moral transgressions, or cognitive interpretations of stimuli (“transgressions”) that violate beliefs about right and wrong, as a predictor of psychological distress. Furthermore, this study tested how perceptions of moral transgressions vary as a function of individuals’ own moral intuitions, or moral foundations. Participants ( …

Musical Expertise Generalizes To Superior Temporal Scaling In A Morse Code Tapping Task, Matthew A. Slayton, Juan L. Romero-Sosa, Katrina Shore, Dean V. Buonomano, Indre Viskontas

Psychology

A key feature of the brain’s ability to tell time and generate complex temporal patterns is its capacity to produce similar temporal patterns at different speeds. For example, humans can tie a shoe, type, or play an instrument at different speeds or tempi—a phenomenon referred to as temporal scaling. While it is well established that training improves timing precision and accuracy, it is not known whether expertise improves temporal scaling, and if so, whether it generalizes across skill domains. We quantified temporal scaling and timing precision in musicians and non-musicians as they learned to tap a Morse code sequence. We …

The Role Of Occupational Therapy For Homeless Women And Women At-Risk Of Homelessness, Kelcey Storkersen

Student Capstone Papers

This paper seeks to identify the occupational barriers and needs of homeless women and women at risk of homelessness. A qualitative research study was performed to learn more about the lived experience of two women at-risk of homelessness. Themes uncovered in this study are described in order to provide more understanding and advocacy for this population. A program proposal was delivered for future fieldwork students to provide occupational therapy students at this resource center.

Diverse Mindfulness Practices For Bipolar Recovery: Qualitative Study Results, Sasha Strong

International Journal of Transpersonal Studies Advance Publication Archive

This study investigated the lived experience of Buddhist-informed mindfulness practice and its utilization in recovery from bipolar disorder (BD) in 9 adult participants. Established mindfulness based interventions (MBIs) decontextualize mindfulness practice from a Buddhist theory base, omitting conceptual frameworks that may have adaptive value in recovery from BD. In interviews, participants reported blending techniques learned from various Buddhist lineages throughout the course of their recovery, as well as a variety of other contemplative practices such as techniques to cultivate adaptive emotions, devotional practices, visualization practices, embodiment practices, investigative practices, and informal daily practice. Mindfulness practice for recovery from BD is …

Leveraging The Power Of Mutual Aid, Coalitions, Leadership, And Advocacy During Covid-19, Daniela Domínguez, Dellanira García, David A. Martínez, Belinda Hernandez-Arriaga

Psychology

The COVID-19 pandemic has shed light on the norms, patterns, and power structures in the United States that privilege certain groups of people over others. This manuscript describes COVID-19 as an unprecedented catalyst for social transformation that underscores the need for multi-level and cross-sectoral solutions to address systemic changes to improve health equity for all. The authors propose that the American Psychological Association and its membership can initiate systemic change, in part, by: (a) supporting mutual aid organizations that prioritize the needs of vulnerable communities; (b) leveraging the efforts and strides APA psychologists have already made within the association, in …

Perceptions And Understanding Of Research Situations As A Function Of Consent Form Characteristics And Experimenter Instructions, Jeremy D. Heider, Jessica L. Hartnett, Emmanuel J. Perez, John E. Edlund

Faculty Publications

Two studies examined how research methodology affected participant behaviors. Study 1 tested (a) consent form perspective (1st, 2nd, or 3rd person) and (b) information on participants’ right to sue upon perceptions of coercion, ability to recall consent information, and performance on experimental tasks. Unexpectedly, participants who received instructions without the right to sue information had significantly better recall of their research rights. Study 2 manipulated (a) consent form complexity (presence or absence of jargon) and (b) the detail of verbal instructions (simple, elaborate); participants who received a consent form with simpler language spent more time on a difficult task, and …

Microhemorrhages In Professional Motocross Athletes: A Case Series, Brianna Millsaps, Philip R. Worts, David C. Berg, Scott O. Burkhart

Faculty Publications - Doctor of Psychology (PsyD) Program

Introduction: Motocross is a sport in which riders race 250–450 cc four-stroke dirt bikes and are potential-ly subjected to a high frequency of head injuries starting at a very young age. The objective of this case series is to present the findings following gradient echo T2-weighted MRI (SWI) upon clinical evaluation after a concussion in 4 young professional motocross racers.

Clinical Findings: Microhemorrhages were found in 2 of 4 riders. Areas of microhemorrhages were not aligned with a previously positive CT finding from a prior concussion in 1 rider.

Conclusions: Microhemorrhages were found in 2 young motocross riders following a …

An Evaluation Of The Advance Directives-Live Action Simulation Training (Ad-Last) Program, Alexandra Rosa Spinelli

Theses and Dissertations

Advance Care Planning (ACP) is a process that captures a patient’s wishes in the case of future circumstances in which they are unable to express them. Studies show that less than one third of the general population has completed some type of formal Advance Directive (AD). There are barriers to completing ADs, and these barriers operate on multiple levels, including, patient, provider and institutional. To improve providers’ capacity to help patients complete ACP, and overcome these barriers, a provider-focused intervention was conducted. The current study is an analysis of archival data collected from the Advance Directives-Live Action Simulation Training (AD-LAST) …

A Phenomenological Study Of The Experiences Of Military Families, Who Have Children With Disabilities And Maladaptive Behavior, With School-Based Mental Health Personnel, Londi J. Segler

Electronic Theses and Dissertations

This qualitative study used a phenomenological approach to capture the lived experiences of military families who have children with disabilities and maladaptive behavior to note risk and protective factors that might impede the mental health development of that population of student. Through interviews with at-home-caregivers, I explored their experiences with public school staff, outside mental health services, and school psychologists. Study findings revealed that participants felt they were going to battle with school staff who were not willing to incorporate culturally responsive practices when working with their children. School staff who implemented regular bi-directional communication were more likely to gain …

Mental Health Advocacy: Building An Interdisciplinary Program For Agriculture Professionals, Abby E. Blankenship, Erica E. Nason, Olivia Hayes, Sebastian Bliss

Contemporary Rural Social Work Journal

The suicide rate among agriculturalists is 3.5 times higher than the general population. A number of external factors related to the farming and veterinary work put individuals in agricultural populations at risk for poor mental health outcomes, including economic variables (e.g. tariffs, market prices), environmental factors affecting yield (e.g. drought, pests), and exposure to difficult or traumatic life events (e.g., mistreatment of animals, loss of crop). Rural values including self-reliance, work orientation, and individualism combined with logistical and systemic barriers to competent behavioral health care further increase risk. Project GROW (Generating Resilience in Our Workforce) is a multifaceted full semester …

Fostering Trauma-Informed Schools By Considering The Experiences Of Teachers In Working With Trauma-Exposed Students, Allison A. Stiles

Electronic Theses and Dissertations

High rates of trauma exposure among youth in the United States and the detrimental effects of trauma on students’ psychosocial and academic outcomes are well-established. Such findings have engendered the emergence of trauma-informed schools across the nation. While research regarding trauma-informed schools has understandably focused on the needs of students, shockingly little is known about teachers’ experiences in working with trauma-exposed students. In particular, very few studies have examined the relationship between teachers’ indirect exposure to student trauma and related symptoms of secondary traumatic stress (STS), as well as factors that may predict STS levels or explain variation in the …

How 6-12th Grade Staff Support Students With Depression: A Pilot Study To Develop Measures Of Implicit Associations, Explicit Attitudes And Helping Behavior, Paul M. Thompson

Electronic Theses and Dissertations

Students with emotional disabilities are disproportionately suspended and expelled in K-12 schools. Attribution theory suggests individuals are less likely to provide assistance to others if they believe the individuals are responsible for their own difficulties. To test attribution theory, this study created new measures of explicit attitudes and implicit associations of licensed 6-12th grade staff regarding students with depression as well as a helping behavior measure of staff toward students with depression. The survey was distributed within a single school district in the western United States. A majority of the sample (N = 52) held a mental health license (60%), …

Comparison Of Resting-State Functional Connectivity In Marmosets With Tracer-Based Cellular Connectivity, Yuki Hori, David J. Schaeffer, Kyle M. Gilbert, Lauren K. Hayrynen, Justine C. Cléry, Joseph S. Gati, Ravi S. Menon, Stefan Everling

Brain and Mind Institute Researchers' Publications

© 2019 Elsevier Inc. Resting-state functional MRI (RS-fMRI) is widely used to assess how strongly different brain areas are connected. However, this connection obtained by RS-fMRI, which is called functional connectivity (FC), simply refers to the correlation of blood oxygen level-dependent (BOLD) signals across time it has yet to be quantified how accurately FC reflects cellular connectivity (CC). In this study, we elucidated this relationship using RS-fMRI and quantitative tracer data in marmosets. In addition, we also elucidated the effects of distance between two brain regions on the relationship between FC and CC across seed region. To calculate FC, we …

Depressogenic Self-Schemas Are Associated With Smaller Regional Grey Matter Volume In Never-Depressed Preadolescents, Pan Liu, Matthew R.J. Vandemeer, Marc F. Joanisse, Deanna M. Barch, David J.A. Dozois, Elizabeth P. Hayden

Brain and Mind Institute Researchers' Publications

© 2020 The Author(s) Self-referential processing (i.e., self-schemas that guide processing of self-descriptive information) emerges early in youth, with deeper encoding of negative self-descriptors and/or shallower encoding of positive self-descriptors causally linked to depression. However, the relationship between depressogenic self-schemas and brain structure is unclear. We investigated associations between self-schemas and regional grey matter volume (GMV) in 84 never-depressed preadolescents oversampled for depression risk based on maternal depression history. Self-schemas were assessed using a Self-Referent Encoding Task (SRET) and regional GMV was indexed via voxel-based morphometry analysis of structural magnetic resonance imaging data. Youths’ positive self-schemas were associated with greater …