Medicine and Health Sciences Commons^™

The Effects Of Physical Function And Genetics On Cognition And Blood Biomarkers In Individuals At-Risk For Alzheimer’S Disease And Related Dementias, Joshua Louis Gills

Graduate Theses and Dissertations

Alzheimer’s disease and related dementia (ADRD) rates are expected to triple by the year 2050. Early detection and specific mitigation efforts are warranted to blunt the alarming rate. Physical function (PF) declines with age, but higher physical function is associated with better cognitive functioning in middle-to- older age individuals. Moreover, greater physical activity (PA) is associated with better global cognition; however, Apoliporotein e4 carriers may not gain the same benefits with exercise. Additionally, plasma phosphorylated tau 217 (p-tau217) has been identified as a novel diagnostic ADRD biomarker which needs further research to examine associations with risk factors. Therefore, the aims …

An Innocent Bystander Walks Into A Bar: The Influence Of Temporal Proximity And Familiarity On Unconscious Transference, Nia Gipson

Graduate Theses and Dissertations

According to The Innocence Project, 69% of DNA exonerations in the United States involved mistaken eyewitness identification as a contributing factor to these errant convictions. Psychologists have contributed towards minimizing mistaken identifications by proposing best practices that law enforcement still follow today. One understudied cause of mistaken eyewitness identification is unconscious transference (UT). UT is a memory error in which a person encountered in an innocent context becomes confused with a person seen in a guilty context (Loftus, 1976). Past research has established some boundary conditions for when UT can occur; however, the limited methodology has resulted in narrow conclusions …

Mentors In Violence Prevention: Differential Impacts On Adolescent Bystander Intentions About Bullying, Dating Violence, And Sexual Harassment, Ayla Mapes

Graduate Theses and Dissertations

Bystander approaches are promising interventions that can engage bystanders as prosocial allies to intervene in interpersonal violence situations among youth within school settings. The Mentors in Violence Prevention (MVP) bystander intervention program targets interpersonal violence using a peer-to-peer mentoring model to engage students in a discussion about violence prevention. Research on the MVP program is promising but limited. The current study examined the specificity of MVP intervention effects in two high school samples. The first was a pre/post-test design that included a smaller sample of high school students who participated in the MVP program in the 2013-2014 academic year. The …

Investigating Fruit And Vegetable Variety In A National Food Co-Op: A Brighter Bites Evaluation, Katherine G. Hearne

Dissertations and Theses (Open Access)

American children eat fewer fruits and vegetables (F&V) and less variety of F&V than recommended for health. Food cooperatives and other programs have become a popular way to increase F&V intake, but little is known about the variety of F&V distributed by these programs or its relationship with program attendance or child F&V intake. Brighter Bites is a national, school-based food co-op distributing rescued, donated, fresh F&V to families in low-income schools. We evaluated, for the first time, the variety of F&V Brighter Bites distributed to families in the 2018-2019 school year and the relationships between that variety and both …

Awareness And Knowledge On Aging And Hiv-Associated Neurocognitive Disorder: Service User And Provider Perspectives In Southern Nevada, Brandon C. Ranuschio

UNLV Theses, Dissertations, Professional Papers, and Capstones

HIV-Associated Neurocognitive Disorder (HAND) is a condition that can affect up to 50% of people living with HIV/AIDS (PLWH) and present as a cluster of neurocognitive difficulties in domains such as attention, memory, concentration, language, information processing, decision-making, problem-solving, and even motor skills. The current study intended to identify awareness and knowledge of HAND among middle-aged and older PLWH and their healthcare or service providers in Southern Nevada. Using a Community-Based Participatory Research approach, participants from the community were recruited to complete a survey that assessed awareness and knowledge of HAND. The survey also assessed the personal experiences of PLWH …

Prevalence And Predictors Of Polypharmacy In Adolescents Who Have Engaged In Sexually Abusive Behaviors, Rebecca Gilley

Electronic Theses and Dissertations

Polypharmacy, or the concurrent use of multiple medications, is associated with detrimental outcomes for patients and has gathered increasing attention within the scientific clinical literature. Pediatric populations warrant special consideration for the practice of polypharmacy, as medication effects are more pronounced in youth and adverse effects may have a lasting impact on development. This dissertation study examined psychotropic prescribing practices in a sample of adolescents who have engaged in sexually abusive behaviors, a subset of justice-involved youth who are at risk for polypharmacy. General prescribing trends were examined, and a principle components analysis involving variables associated with risk of polypharmacy …

Trauma And Resilience Among Migrant Children From Mexico And The Northern Triangle Eroute To The United States, Georgina Sanchez-Garcia

Open Access Theses & Dissertations

Children who experience the phenomenon of migration from the Northern Triangle region and Mexico en route to the United States face pressing problems with psychosocial consequences that ostensibly affect them and are reflected in the violation of their human rights. We studied trauma and resilience among migrant children from Mexico and the Northern Triangle nations â??Guatemala, El Salvador, and Hondurasâ?? who are uprooted from their communities to undertake the dangerous overland journey to the United States (Lusk & Sanchez-Garcia, 2021; Rodriguez, 2020; UNICEF, 2018). The experience of such migration for children can be fraught with hardship, and it may have …

Racial Differences In Tobacco Use And Risk Factors Among Young Adults: Roles Of Expectancies And Emotion Regulation, Laurel Brockenberry

Psychology Theses & Dissertations

African Americans experience higher mortality from lung cancer and other smoking-related diseases than Caucasian Americans (Kochanek et al., 2016) despite engaging in cigarette and e-cigarette use significantly less or at comparable rates to other racial groups (CDC, 2015; Schoeborn, 2013). During adolescence, smoking prevalence is lower among African Americans than Caucasian Americans, but there is a “cross-over effect” whereby smoking rates become similar later in adulthood (Belgrave et al, 2010). The mechanisms driving this effect are poorly understood. Thus, examining motivating factors for tobacco use, such as outcome expectancies and emotion regulation, may be especially illuminating for young adult African …

An Investigation Of Healthcare Professionals’ Perspectives On The Tasks Of Mental Health Counselors In Hospital Settings, Suelle Micallef Marmara

Counseling & Human Services Theses & Dissertations

With the global mental health implications reported by the spread of COVID 19 (Javed et al., 2020) and the amplified mental health illnesses reported by the State of Mental Health in America (Reinert et al., 2021), there is an increased need to address psychological and emotional health along with physical health. Mental Health Counselors (MHCs) can be the next professional body to support the multidisciplinary teams within hospital settings to complement holistic care focusing on physical and emotional well-being. Researchers have demonstrated addressing the psychological needs of patients from their first admissions to the hospital has significant positive implications on …

Cognitive Testing For Sport Concussion: The Immediate Post-Concussion Assessment And Cognitive Testing (Impact), Julia E. Maietta

UNLV Theses, Dissertations, Professional Papers, and Capstones

Sport concussion is among the most common injuries for an athlete to experience during sport participation. Because of the complex pathophysiological process that affects the brain during and after concussion, symptoms can be heterogeneous in presence and severity. Although most acute symptoms (e.g., headache, slowed processing speed, loss of consciousness, irritability, depression, anxiety) resolve within seven to 10 days for most athletes, there is evidence that higher initial symptom burden and other genetically based differences can lead to longer symptom duration and complicated recovery post-concussion. Because structural changes that commonly occur as a result of concussion (e.g., diffuse axonal injury) …

How Valuable Are Clinical Neuropsychological Assessments? A Meta-Analysis Of Neuropsychological Tests With Comparison To Common Medical Tests And Treatments, Murphy N. Harrell

Graduate Theses and Dissertations (2019 - present)

There has been a general decrease in neuropsychological assessments at a time when medical diagnostic technology and treatments have expanded, leading to a faulty assumption that medical tests and healthcare treatments provide more reliable or valid data than psychological assessments. A landmark report from the American Psychological Association’s (APA) Psychological Assessment Work Group (PAWG) found that validity coefficients for many psychological tests were indistinguishable from those of medical tests (Meyer et al., 2001). An updated systematic review of the advancement in neuropsychological testing is essential to the continued advancement of the value of neuropsychological assessment in healthcare. This meta-analysis sought …

Children’S Positive Peer Relationships And Their Bullying Behaviors: A Latent Profile Analysis, Lauren Mutignani

Graduate Theses and Dissertations

In the current study, I aim to expand upon traditional methods for classifying children based on positive peer nominations and contribute to the field’s understanding of high-status bullies who maintain social resources despite bulling behaviors (e.g., van der Ploeg et al., 2020). Both reciprocated and one-sided (i.e., received and sent) positive peer nominations were used to distinguish socially meaningful subgroups. Participants included 659 children from 34 classrooms (M Age = 9.31 years, SD = .49 years; girls = 50.6%; Hispanic/Latino/a/x = 42.5%, White/European American = 29.9%, Black/African American = 2.3%, Asian/Asian American/Pacific Islander = 11.7%, Native American = 2.3%, Bi/Multiracial …

An Evaluation Of The Convergent Construct Validity Of The Boldness Inventory Of Psychopathy Using A Five-Minute, 10% Carbon-Dioxide-Enriched Air Challenge, Morgan Alexandra Hill

Graduate Theses and Dissertations

Psychopathy is a constellation of maladaptive interpersonal, affective, and behavioral features, including grandiosity, manipulativeness, emotional detachment, and impulsivity (Hare, 2003). Fearlessness, immunity to stress, self-assurance, and social dominance are considered to be adaptive features of psychopathy. Patrick and colleagues (2009) sought to reconcile differences between opposing conceptualizations of psychopathy by formulating a triarchic model of the condition. One core construct in this model, boldness, captures an ability to remain calm in the face of threat, an appetite for dangerous or risky activities, and an increased tolerance for uncertainty and danger. Boldness is believed to originate from differences in the brain’s …

Enhancing Physician Perspectives Of Skilled Occupational Therapy Services For Patients With Rheumatoid Arthritis, Valerie S. Trinidad

Department of Occupational Therapy Entry-Level Capstone Projects

This Capstone Project, with a focus in research, sought to identify a relationship between self-reported functional performance and participation restriction as described by satisfaction with one’s execution or participation in a described occupation. A correlational study design was employed under the mentorship of Dr. Thomas Decker, EdD, OTD, OTR/L who oversaw all IRB processes, documentation, study development and deployment, as well as co-authored and provided mentorship for creation of a publishable manuscript of this project. The established Health Assessment Questionnaire Disability Index (HAQ-DI) and the newer Keele Assessment of Participation (KAP) were the two outcome measures of focus for surveying …

Bias In Measurement Of Autism Symptoms By Spoken Language Level And Non-Verbal Mental Age In Minimally Verbal Children With Neurodevelopmental Disorders, Shuting Zheng, Aaron Kaat, Cristan Farmer, Audrey Thurm, Catherine A. Burrows, Stephen Kanne, Stelios Georgiades, Amy Esler, Catherine Lord, Nicole Takashashi, Kerri P. Nowell, Elizabeth A. Will Ph.D., Jane E. Roberts, Somer L. Bishop

Faculty Publications

Increasing numbers of children with known genetic conditions and/or intellectual disability are referred for evaluation of autism spectrum disorder (ASD), highlighting the need to refine autism symptom measures to facilitate differential diagnoses in children with cognitive and language impairments. Previous studies have reported decreased specificity of ASD screening and diagnostic measures in children with intellectual disability. However, little is known about how cognitive and language abilities impact the measurement of specific ASD symptoms in this group. We aggregated a large sample of young children (N = 1196; aged 31-119 months) to examine measurement invariance of ASD symptoms among minimally verbal …

Plasma Amyloid-Β Dynamics In Late-Life Major Depression: A Longitudinal Study, Nunzio Pomara, Davide Bruno, Chelsea Reichert Plaska, Jaime Ramos-Cejudo, Ricardo S Osorio, Anilkumar Pillai, Bruno P Imbimbo, Henrik Zetterberg, Kaj Blennow

Faculty, Staff and Student Publications

Depressed individuals are twice as likely to develop Alzheimer’s disease (AD) as compared to controls. Brain amyloid-β (Aβ) deposition is believed to have a major role in AD pathogenesis but studies also suggest associations of Aβ dynamics and depression. The aim of this study was to test if plasma Aβ levels are longitudinally associated to late-life depression. We measured plasma levels of amyloid-β1-40 (Aβ40) and amyloid-β1-42 (Aβ42) peptides longitudinally for three consecutive years in 48 cognitively intact elderly subjects with late-life major depressive disorder (LLMD) and 45 age-matched cognitively healthy controls. We found that the Aβ42/Aβ40 plasma ratio was significantly …

Let's Get Physical: Exploring The Socioemotional Motivators Of Group Exercise For Older Adults, Tessneem S. Hasan, Alyssa R. Minton, Jason Snyder, Joseph A. Mikels

DePaul Discoveries

Approximately 75% of active adults in the U.S. do not meet the recommended levels of overall physical activity (CDC, 2021a). Given the beneficial impact of physical activity on health, an 8-week long, evidence-based group exercise program—Fit & Strong! (F&S!)—was created to improve the health of older adults (Hughes et al., 2004, 2006, 2010). Despite the clear physical benefits of F&S!, it remains unknown what motivates F&S! participants to initially participate in the program and also throughout the program. Drawing from core notions of socioemotional selectivity theory (SST; Carstensen, 2006), research has found that older adults are highly motivated to exercise …

Ketamine For Acute Pain After Trauma: The Kapt Randomized Controlled Trial, Thaddeus J Puzio, James Klugh, Michael W Wandling, Charles Green, Julius Balogh, Samuel J Prater, Christopher T Stephens, Paulina B Sergot, Charles E Wade, Lillian S Kao, John A Harvin

Faculty, Staff and Student Publications

BACKGROUND: Evidence for effective pain management and opioid minimization of intravenous ketamine in elective surgery has been extrapolated to acutely injured patients, despite limited supporting evidence in this population. This trial seeks to determine the effectiveness of the addition of sub-dissociative ketamine to a pill-based, opioid-minimizing multi-modal pain regimen (MMPR) for post traumatic pain.

METHODS: This is a single-center, parallel-group, randomized, controlled comparative effectiveness trial comparing a MMPR to a MMPR plus a sub-dissociative ketamine infusion. All trauma patients 16 years and older admitted following a trauma which require intermediate (IMU) or intensive care unit (ICU) level of care are …

Perceived Stress And Salivary Biomarkers In Educators: Comparison Among Three Stress Reduction Activities, Doreen Wagner, Sharon M. Pearcey

Faculty Articles

Background: The teaching profession is a potentially stressful occupation with up to 30% of all novice teachers leaving the profession and annual teacher turnover is higher when compared with turnover of all other occupations. This study investigated the effects of a one-time stress reduction activity (meditation, yoga, or aerobic exercise) in university and K-12 educators who were part of one-day seminar on Stress Reduction.

Methods: Participants (N = 26) self-selected their stress reduction activity, completed a demographic questionnaire, educator stress self-assessment tool, and visual analogue scales indicating current stress levels. Salivary cortisol and amylase levels were measured before, immediately after, …

Implications For Cross-Training Between Applied Behavior Analysis And Speech-Language Pathology, Katherine Lynn Isaacson

Speech and Hearing Sciences Publications

This paper is to provide clarity about the overlaps between the fields of Applied Behavior Analysis (ABA) and speech-language pathology, including evaluation, assessment, intervention planning, and treatment of language development, nine articles were selected for a review of terms and definitions, philosophical and theoretical underpinnings, and licensure/certification requirements pertaining to both scopes of practice. Behavior analysts and speech-language pathologists (SLPs) are likely to provide intervention alongside one another due to their frequent provision of intervention with individuals diagnosed with autism spectrum disorder (ASD). Despite broad, initial overlaps between the professions, the required educational coursework, supervised fieldwork and clinical practicums, and …

The Lived Experience Of Postpartum Anxiety During Covid-19: A Hermeneutic Phenomenological Study, Walker Ladd Phd, Jenny De Decker

The Qualitative Report

The experience of pregnancy and postpartum anxiety disorders results in adverse birth outcomes and the disrupted development of infants and children. Since the COVID-19 Pandemic, the Centers for Disease Control and Prevention (CDC) has designated pregnant and postpartum women as more vulnerable to COVID-19 (CDC, 2021), and perinatal mood and anxiety disorders rates have increased. However, research regarding the lived experience of women with postpartum anxiety (PPA) during a global pandemic remains lacking. Using van Manen’s hermeneutic phenomenological research method, we interviewed eight women self-identifying as having had PPA during the COVID-19 pandemic. Analysis revealed five themes describing the lived …

Recognizing And Disrupting Stigma In Implementation Of Hiv Prevention And Care: A Call To Research And Action, Sarit A. Golub, Rachel A. Fikslin

Publications and Research

Introduction: There is robust evidence that stigma negatively impacts both people living with HIV and those who might benefit from HIV prevention interventions. Within healthcare settings, research on HIV stigma has focused on intra-personal processes (i.e. knowledge or internalization of community-level stigma that might limit clients’ engagement in care) or inter-personal processes (i.e. stigmatized interactions with service providers). Intersectional approaches to stigma call us to examine the ways that intersecting systems of power and oppression produce stigma not only at the individual and interpersonal levels, but also within healthcare service delivery systems. This commentary argues for the importance of analysing …

Mothers’ Reflections On Cat Ownership For A Child With Autism Spectrum Disorder During Covid-19, Saskia Keville, Sophia De Vita, Amanda K. Ludlow

People and Animals: The International Journal of Research and Practice

Animal- assisted interventions are increasingly used as a complementary therapy in clinical practice to support people with autism spectrum disorder (ASD), with promising outcomes compared to traditional therapies. Less is understood about the therapeutic benefits of more accessible and affordable small pet ownership for families with a child with ASD, alongside the pets’ welfare living in these homes. This study explored the experiences of cat ownership for young people with ASD from the perspective of their mothers during a time of transition generated by COVID-19. Semi-structured interviews were conducted with six mothers and transcripts analyzed using reflexive thematic analysis. Three …

Developing Standards For Cultural Competency Training For Health Care Providers To Care For Lesbian, Gay, Bisexual, Transgender, Queer, Intersex, And Asexual Persons: Consensus Recommendations From A National Panel, Mandi L. Pratt-Chapman, Kristen Eckstrand, Amorie Robinson, Lauren B. Beach, Charles Kamen, Alex S. Keuroghlian, Scott Cook, Asa Radix, Markus P. Bidell, Daniel Bruner, Liz Margolies

Publications and Research

Purpose: Lesbian, gay, bisexual, transgender, queer, intersex, and/or asexual and other sexual and gender diverse persons (LGBTQIA + or SGD persons) experience barriers to equitable health care. The purpose of this article is to describe a collaborative process that resulted in core cultural competency recommendations addressing training for those who provide health care and/or social services to LGBTQIA + patients.

Methods: In 2018 and 2019, Whitman-Walker Health, a Federally Qualified Community Health Center in Washing- ton, DC, and the National LGBT Cancer Network purposively selected leaders of community clinics and community-based organizations, cultural competency trainers, and clinicians and researchers with …

Coach And Athlete Perceptions Of The Effects Of The Menstrual Cycle On Female Athletic Performance, Erin Dietz

Honors Projects

The purpose of this study is to examine the knowledge of the effects of the menstrual cycle on female athletic performance from both athletes and their coaches at the NCAA Division III level. Recommendations for coaches based on the findings of the research are provided. The study investigates whether female athletes and their coaches are aware of the physiological and psychological effects of the menstrual cycle and how they are managed throughout the course of a sport season.

Origins Of High Latitude Introductions Of Aedes Aegypti To Nebraska And Utah During 2019, Andrea Gloria-Soria, Ary Faraji, Jeff Hamik, Gregory White, Shanon Amsberry, Matthew Donahue, Bryan Buss, Evlyn Pless, Luciano Veiga Cosme, Jeffrey R. Powell

Department of Educational Psychology: Faculty Publications

Aedes aegypti (L.), the yellow fever mosquito, is also an important vector of dengue and Zika viruses, and an invasive species in North America. Aedes aegypti inhabits tropical and sub-tropical areas of the world and in North America is primarily distributed throughout the southern United States states and Mexico. The northern range of Ae. aegypti is limited by cold winter months and establishment in these areas has been mostly unsuccessful. However, frequent introductions of Ae. aegypti to temperate, non-endemic areas during the warmer months can lead to seasonal activity and disease outbreaks. Two Ae. aegypti incursions were …

Comparison Of Unmet Health Care Needs In Children With Intellectual Disability, Autism Spectrum Disorder And Both Disorders Combined, K. Haller, Adrienne Stolfi, John Duby

Medical Education Faculty Publications

Background: The purpose of this study was to assess the unmet health care needs of children with intellectual disability (ID) compared with children with autism spectrum disorder (ASD) and whether access to health insurance coverage is a contributing factor. Children with ID may be masked in the health care system due to increased diagnosis and awareness of ASD. The needs, unmet needs and insurance coverage of children with ID alone, ASD alone, and co-occurring ID and ASD were assessed in this study.

Methods: The 2016 to 2019 United States' Census Bureau National Survey of Children's Health was used to determine …

‘Mapping’ Moral Engagement In The Solution-Focused Approach Through Macintyre’S Model Of Practice, Brian K. Jennings

Journal of Solution Focused Practices

I attempt to answer Trish Walsh’s two questions about the ‘maps’ that might exist for moral engagement in the ‘helping’ professions and how these might relate to the Solution-Focused Approach (Walsh, 2010). I seek to do this by exploring the narrative of the emergence of the Solution Focused Approach from the perspective of Alasdair MacIntyre’s concept of a ‘practice’ (MacIntyre, 1985) with the aim of providing the basis for ‘map’ for moral engagement by Solution-Focused Practitioners. To this end I attempt to interpret the Solution Focused Approach as a MacIntyreian ‘practice’ in which virtues (as ‘human qualities’) emerge out of …

Simulated Owl Predation During Foraging Differentially Alters Choice And Fear Behavior Between Sex In Rats, Meghan M. Olsen

Research Psychology Theses

Existing research on the predator cue circuit has indicated there are observed differences between sexes of animals either directly or indirectly exposed to a predator stimulus. Exposure increases predator directed attention, and overrides other motivational systems (hunger, pain, reproductive behavior). Little research has explored whether exposure to predation is associated with differential responses to non-predator related decision-making across a variety of tasks. Therefore, understanding the prioritization of motivational states when a predator stressor is present can aid in understanding sex differences in these processes in both adaptative and maladaptive conditions. To determine how repeated exposure to a predator stressor differentially …

United States Healthcare Burden Of Pediatric Functional Gastrointestinal Pain Disorder Hospitalizations From 2002 To 2018, John M Hollier, Jason L Salemi, Robert J Shulman

Faculty, Staff and Students Publications

BACKGROUND: The healthcare burden of pediatric functional gastrointestinal pain disorders (FGIDs) is unclear. Our study aimed to characterize the burden of these hospitalizations in the United States (US).

METHODS: We utilized the US National Inpatient Sample from 2002 to 2018 to capture pediatric hospitalizations (ages 4 to 18 years old) with a primary discharge diagnosis of abdominal pain, constipation, irritable bowel syndrome, dyspepsia, abdominal migraine, cyclic vomiting syndrome, or fecal incontinence. We calculated the FGID hospitalization prevalence rate, length of stay (LOS), and inflation-adjusted costs annually and assessed for statistically significant trend changes using joinpoint analyses.

KEY RESULTS: 22.3 million …