Medicine and Health Sciences Commons^™

Resilience To Stress Across The Lifespan: Childhood Maltreatment, Heart Rate Variability, And Bereavement, Michelle A Chen, Robert Suchting, Julian F Thayer, Christopher P Fagundes

Faculty, Staff and Student Publications

Following a stressful life event, there is considerable variation in how individuals respond and adapt. Multiple models of risk and resilience show that adverse childhood experiences may be associated with an individual's response to stress later in life. While there is considerable support that early adversity can sensitize the stress response system and lead to adverse outcomes later in life, there is mounting evidence that in adolescence and young adulthood, certain biological predispositions to stress may be associated with resilience in the context of subsequent stressors. In this study, we evaluated how individual differences in vagally mediated heart rate variability …

Circumventing Ableism: A Grounded Theory Study Exploring Caregiver Strategies To Promote A Positive Identity, June Furr

All Dissertations

This qualitative research study explores how caregivers and persons with disabilities navigate the rhetoric of disability and caregiving through the interviews of fifteen caregivers and fifteen persons with disabilities using the lens of grounded theory and Burke’s (1952) dramatistic pentad. Significant findings describe how focused disability description can circumvent ableism when rhetorical resources that assist caregivers and persons with disabilities to navigate the rhetoric in disability descriptions are provided. Disability description theory includes the three stages that define, collaborate and revise, and practice and apply a disability description. This qualitative research offers an introduction into the phenomenon of …

One Immune System Plays Many Parts: The Dynamic Role Of The Immune System In Chronic Pain And Opioid Pharmacology, Sanam Mustafa, Juliana E Bajic, Benjamin Barry, Samuel Evans, Kariel R Siemens, Mark R Hutchinson, Peter M Grace

Faculty, Staff and Student Publications

The transition from acute to chronic pain is an ongoing major problem for individuals, society and healthcare systems around the world. It is clear chronic pain is a complex multidimensional biological challenge plagued with difficulties in pain management, specifically opioid use. In recent years the role of the immune system in chronic pain and opioid pharmacology has come to the forefront. As a highly dynamic and versatile network of cells, tissues and organs, the immune system is perfectly positioned at the microscale level to alter nociception and drive structural adaptations that underpin chronic pain and opioid use. In this review, …

An Examination Of The Association Of Religiosity, Purity Culture, And Religious Trauma With Symptoms Of Depression And Anxiety, Kaelyn R. Griffin

UNLV Theses, Dissertations, Professional Papers, and Capstones

While no consistent definition yet exists for religious trauma, religious abuse is typically defined as a misuse of authority by a spiritual leader to coerce, control, or exploit those under their leadership, which may in turn lead to the experience of religious trauma. Numerous studies suggest that experiencing abuse within a religious environment is a both global phenomenon and common experience. The impact of religious abuse has recently gained greater media attention, specifically related to the social and psychological impact of leaving high-cost religious groups (i.e., those with rigid rules or groups from which departure leads to isolation and rejection …

Children’S Disclosure Of School Bullying: The Relation Between Peer Victimization, Internalizing Symptoms, Negative Affect, And Gender, Julia L. Kiefer

Graduate Theses and Dissertations

Children who are bullied by their peers are at risk for several negative developmental outcomes and are therefore advised to tell an adult when they are. However, victims of school bullying are often reluctant to disclose to adults that they are being bullied. Some bullied children also experience symptoms of anxiety or depression, which could further reduce their likelihood of telling an adult. In this study, I tested the degree to which children’s internalizing symptoms predicted their likelihood of telling adults about being bullied at school, and if this relation was exacerbated by children’s negative feelings associated with telling an …

Predicting E-Cigarette Use Among Emerging Adults Using Perceived Social Norms And Outcome Expectancies, Stephen N. Hanson

Psychology Theses & Dissertations

Despite low rates of combustible tobacco use rates among adolescents and young adults, e-cigarettes continue to gain popularity. A few factors have been shown to be related to e-cigarette use based on prior research. One such example is social enhancement expectancies. Additionally, greater perceptions of harm have been found to be inversely related to e-cigarette use such that those that expect increased risk to their health are less likely to report using e-cigarettes. I hypothesized that social enhancement expectancies would mediate the relationship between perceptions of social norms and e-cigarette dependence. I also hypothesized that perceived harm, such as greater …

The Effect Of Minority Stress On Sexual Minority College Students' Mental Health: The Role Of General Social Support And Sexuality-Specific Social Support, Lee A. Golembiewski

Psychology Theses & Dissertations

Sexual minority (SM) college students continue to face greater mental health problems relative to their heterosexual peers (Woodford et al., 2014; Wilson & Liss, 2022). According to minority stress theory, SM individuals face distal (e.g., heterosexist discrimination) and proximal (e.g., expectations of rejection, internalized homophobia, and concealment) stressors related to their SM identity which can have negative effects on their mental health (Douglass & Conlin, 2020; Meyer, 2003). However, social support has been hypothesized to help protect against the effects of minority stress experienced by SM individuals (Cohen & Wills, 1985; Moody & Smith, 2013). Most of the existing research …

Inner Portraits, Bethany Salisbury

Graduate Theses

This paper investigates the many interconnected layers of women’s mental health through portraiture and how animal and plant symbolism can represent the way women's hormones and bodily health affect their mental health. I reveal how the artwork created presents these connections and inner mental health narratives to the viewer, creating a space of empathy, destigmatization, and self-reflection. This body of portraiture art connects five women through a series of both two-and three-dimensional portraits based on interviews using my own adaptation of Sara Lawrence-Lightfoots’ (1983) portrait methodology.

Women and non-binary individuals have always dealt with difficult interactions of bodily and mental …

Association Between The Epigenetic Lifespan Predictor Grimage And History Of Suicide Attempt In Bipolar Disorder, Camila N C Lima, Emese H C Kovács, Salahudeen Mirza, Alexandra Del Favero-Campbell, Alexandre Paim Diaz, Joao Quevedo, Benney M R Argue, Jenny Gringer Richards, Aislinn Williams, John A Wemmie, Vincent A Magnotta, Jess G Fiedorowicz, Jair C Soares, Marie E Gaine, Gabriel R Fries

Faculty, Staff and Student Publications

Bipolar disorder (BD) has been previously associated with premature mortality and aging, including acceleration of epigenetic aging. Suicide attempts (SA) are greatly elevated in BD and are associated with decreased lifespan, biological aging, and poorer clinical outcomes. We investigated the relationship between GrimAge, an epigenetic clock trained on time-to-death and associated with mortality and lifespan, and SA in two independent cohorts of BD individuals (discovery cohort - controls (n = 50), BD individuals with (n = 77, BD/SA) and without (n = 67, BD/non-SA) lifetime history of SA; replication cohort - BD/SA (n = 48) and BD/non-SA (n = 47)). …

Depression, Stress And Regional Cerebral Blood Flow, Joshua Chiappelli, Bhim M Adhikari, Mark D Kvarta, Heather A Bruce, Eric L Goldwaser, Yizhou Ma, Shuo Chen, Seth Ament, Alan R Shuldiner, Braxton D Mitchell, Peter Kochunov, Danny Jj Wang, L Elliot Hong

Faculty, Staff and Student Publications

Decreased cerebral blood flow (CBF) may be an important mechanism associated with depression. In this study we aimed to determine if the association of CBF and depression is dependent on current level of depression or the tendency to experience depression over time (trait depression), and if CBF is influenced by depression-related factors such as stressful life experiences and antidepressant medication use. CBF was measured in 254 participants from the Amish Connectome Project (age 18-76, 99 men and 154 women) using arterial spin labeling. All participants underwent assessment of symptoms of depression measured with the Beck Depression Inventory and Maryland Trait …

Comparison Of Neurocognitive And Quality-Of-Life Outcomes In Pediatric Craniopharyngioma Patients Treated With Partial Resection And Radiotherapy Versus Gross-Total Resection Only, Guillermo Aldave, M Fatih Okcu, Murali Chintagumpala, Lucia Ruggieri, Charles G Minard, Fatema Malbari, Lisa E Mash, Arnold C Paulino, Susan Mcgovern, Uma Ramaswamy, William Whitehead, Lisa S Kahalley

Faculty, Staff and Students Publications

OBJECTIVE: The optimal management of pediatric craniopharyngioma patients remains controversial, shifting from radical resection (gross-total resection [GTR]) to a more conservative approach with partial resection/biopsy followed by radiotherapy (PR+RT). To the authors' knowledge, no previous studies have compared neurocognitive and quality-of-life (QOL) outcomes between the two main treatments. In this study, the authors compared changes in intellectual, adaptive, and QOL scores in children treated for craniopharyngioma with GTR and those treated with PR+RT.

METHODS: Patients underwent annual neurocognitive and QOL evaluations for up to 10 years posttreatment, including the Full-Scale IQ, Verbal Comprehension Index (VCI), Perceptual Reasoning Index (PRI), Working …

Rural Social Work Practice: Trauma-Focused Interventions Social Workers Use, Jose Carbajal

Journal of Human Services: Training, Research, and Practice

This research study examines rural social workers’ level of trauma knowledge and trauma treatment self-efficacy and the use of evidence-based interventions (CBT, TF-CBT, CPT, EMDR and PE). A retrospective design was used to examine Texas rural social workers’ use of evidence-based interventions. The Texas rural social worker sample (N=19) was extrapolated from a larger study (N=1007) conducted in 2014 examining Texas social workers’ trauma treatment and their use of evidence-based interventions. Descriptive and correlation statistical procedures were implemented to analyze the data for the current study. The results show social workers’ knowledge of trauma and treatment self-efficacy scores are above …

The Mental Health Epidemic In Veterinary Medicine: An Analysis Of Burnout In The Veterinary Field, Hannah Eckstein

Undergraduate Theses

The Mayo Clinic describes burnout as a specific type of stress that involves a state of physical or emotional exhaustion. This exhaustion can lead to a lowered sense of accomplishment and negative personal identity. Despite burnout not being an actual diagnosis, many researchers believe there are several mental health components that contribute to burnout, such as depression and anxiety. Several factors are known to contribute to specifically work-related burnout, including lack of control, work-life imbalance, lack of social support, and extremes of the activity. All of the above factors relate to the veterinary field. In one study, 6.8% of male …

Youths’ Sense Of Mastery Scores In Correlation To Ptsd Criterion D Scores & Total Ptsd-Ri Scores, Katherine Conklin, Amanda Mraz

Undergraduate Research Symposium Posters

Childhood resilience levels impact the severity of posttraumatic stress disorder (PTSD). Resiliency is defined as a personal characteristic fostering effective coping, adaptive functional abilities, and motivation.

Examining Differences In Ptsd Symptomatology Among Youth Who Have Experienced Sexual And Psychological Maltreatment Using Nonparametric Analyses, Emma Domschot, Vanni Jefferson V. Arcaina

Undergraduate Research Symposium Posters

Child sexual abuse, even when accounting for co-occuring risk factors, may be predictive of worse clinical outcomes when comparing to other types of trauma (Kisiel et al., 2014). However, contrasting research suggests that psychological maltreatment may independently contribute to a negative risk of clinical outcomes comparable to child sexual abuse (Hodgon et al., 2014). Other studies suggest that complex trauma, in terms of experiencing prolonged and several traumas over a period of time, may often lead to an increased risk of post-traumatic stress disorder (John et al., 2019). The current study aimed to examine differences in PTSD symptomatology among youth …

Sexual Abuse And Interpersonal Difficulties In Youth, Priscilla Herrera, Kinsey Ellis

Undergraduate Research Symposium Posters

Researchers have found childhood sexual abuse victimization to be associated with impairments in trust, social comfort, and quality of interpersonal relationships1,2,3. Research which investigates the unique relationship between sexual abuse and interpersonal difficulties among youth with a history of child maltreatment is limited. The present study aimed to investigate interpersonal functioning differences in maltreated youth who have and have not experienced sexual abuse.

Emotional Reactivity Predicts Dissociation In Maltreated Youth, Jaelin Isquith, Kinsey Ellis

Undergraduate Research Symposium Posters

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) defines dissociation as “disruption in the usually integrated functions of consciousness, memory, identity or perception of the environment”11. Dissociation most commonly occurs after a traumatic experience and can take many forms; Subtypes include dissociative amnesia, absorption and imaginative involvement, passive influence, and depersonalization and derealization. Dissociation has been linked to several negative outcomes such as increased risk for development of personality disorders, suicidal ideation, and self-harm2,3. Risk factors for dissociation have been understudied in child and adolescent populations. One factor that has been found to be related to severity of dissociative …

Experiencing Moral Distress Within The Intimate Partner Violence & Sexual Assault Workforce, Rachel J Voth Schrag, Sophia Fantus, Sarah Leat, Saltanat Childress, Leila Wood

Faculty, Staff and Student Publications

PURPOSE: Moral distress (MD) refers to the psychological disequilibrium that emerges when institutional policies and/or practices conflict with an individual's professional values and ethics. MD has been interrogated frequently in health care and ancillary medical settings, and has been identified as a critical barrier to enhanced organizational climate and patient care. However, little work has investigated experiences of MD among members of the intimate partner violence (IPV) and sexual violence (SV) workforce.

METHODS: This study investigates MD in a sample of IPV and SV service providers via secondary analysis of 33 qualitative interviews conducted with service providers in the summer …

Dental Fear, Anxiety, And Phobia – Behavioral Management And Implications For Dentists, Nadya Tsetsova Avramova

Journal of Mind and Medical Sciences

Clinical management of patients with dental fear, anxiety, and phobia could be a major challenge to daily practice of dental professionals. The aim of the current review was to expand the modern consideration with respect to these issues, and therefore to discuss basic approaches and psychological techniques for management of oral health behaviors that should be employed in dentistry. This paper presents detailed description of the characteristics of dentist-patient therapeutic relationship as well as the most used techniques to cope with dental fear, anxiety, and phobia - relaxation techniques, cognitive-behavioral therapy (CBT), hypnosis and melotherapy. We can still argue that …

Targeting The Gap In Mental Health Advocacy For First-Year College Students, Hailey Kurtz

Honors Projects

The transition from high school to attending a university has been shown to have an impact on the mental health and well-being of first-year university students. First-year students struggle with anxiety and depression in relation to being in a new environment, feeling lonely, fitting in, and taking more academically rigorous coursework. Current students have an awareness of what mental health and well-being resources on their campus are available to them, but such resources are not widely used, though a majority of students indicate that they do or have struggled with their mental health. This indicates that though students are struggling …

Comparing Levels Of Situational Empathy Based On Medium Of Exposure To Covid-19 Mortality Information And Proximity To Others, Beth Durkin

Honors Projects

In response to the COVID-19 pandemic, many people expressed a lax attitude to the policies put in place to keep the public safe despite the high risk of infection and its devastating effects on health across the United States. It is possible that this response may be partially due to a “numbness to numbers,” a phenomenon that describes diminished empathy for a large group of people experiencing a negative event (eg. COVID-19). The present study explored the relationship between levels of situational empathy and the medium of exposure to COVID-19 mortality information (eg. personal story or fact sheet) in an …

Low-Dose Psilocybin Enhances Novel Object Recognition But Not Inhibitory Avoidance In Adult Rats, Claire E. Miller, Colin R. Del Valle, Margaret M. Naylor, Heather R. Sparkman, Connor M. Cruea, Rachel E. Rice, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Given the recently renewed interest in using psychedelics to aid in the treatment of psychological disorders, we aimed to examine the impact of psilocybin, a 5-HT_2A agonist, on learning and memory in rodents. Previous work has demonstrated that psilocybin and other 5-HT_2A agonists can enhance fear conditioning, fear extinction, and novel object recognition (NOR). Thus, we predicted that low doses of psilocybin would enhance inhibitory avoidance (IA) and NOR memory. In the first experiment, adult male and female Sprague-Dawley rats underwent step-through IA training (involving 0.45, 0.65, or 1 mA scrambled footshock) and were injected intraperitoneally (i.p.) with …

Tunnel Vision, False Memories, And Intrusive Memories Following Exposure To The Trier Social Stress Test, Chloe N. Cordes, Cassidy L. Pfister, Kayla M. Boaz, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Shannon B. Carnes, Boyd R. Rorabaugh, Phillip R. Zoladz

ONU Student Research Colloquium

Most research examining the impact of stress on learning and memory has exposed participants to a stressor and measured how it affects learning and memory for unrelated material (e.g., list of words). Such work has been helpful, but it has not been the most translational to the human condition. When considering phenomena such as intrusive memories in post-traumatic stress disorder (PTSD) or an eyewitness's memory for a crime, it is most useful to know what an individual remembers about the stress experience itself, not unrelated information. In prior work, investigators used a modified version of the Trier Social Stress Test …

Impact Of Acute Stress, Sex, And Childhood Maltreatment On Fear Learning And Fear Generalization In A Fear-Potentiated Startle Paradigm, Kayla M. Boaz, Chloe N. Cordes, Cassidy L. Pfister, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Boyd R. Rorabaugh, Seth D. Norrholm, Phillip R. Zoladz

ONU Student Research Colloquium

Many researchers approach the etiology of trauma-, stressor-, and anxiety-related mental disorders from the perspective of classical conditioning processes gone awry. According to this view, abnormal associative relationships between conditioned and unconditioned stimuli may underlie pathological anxiety and result in unusually intense fear memories or fear memories that cannot be properly extinguished. Recent work has expanded on this view by showing that many psychological disorders involving pathological anxiety are associated with an exaggerated form of stimulus generalization, leading individuals with such disorders to respond with fear and anxiety to a variety of contexts and cues that should not be threatening. …

Psilocybin Prevents Symptoms Of Hyperarousal And Enhances Novel Object Recognition In Rats Exposed To The Single Prolonged Stress Paradigm, Colin R. Del Valle, Heather R. Sparkman, Margaret M. Naylor, Connor M. Cruea, Rachel E. Rice, Claire E. Miller, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Pharmacotherapy for stress-related psychological disorders remains inadequate. Patients who are treated with conventional pharmacological agents frequently report negligeable symptom reduction, and, in most cases, less than 50% experience full remission. Clearly, there is a need for additional pharmaceutical research into both established and novel approaches to alleviate these conditions. Over the past several years, there has been a renewed interest in the use of psychedelics to aid in the treatment of psychological disorders. Several studies have reported promising results in patients with major depression, anxiety disorders, and post-traumatic stress disorder (PTSD) following treatment with psychedelic agents such as lysergic acid …

A Comparison Of Nonverbal And Paraverbal Behaviors In Simulated And Virtual Patient Encounters, Sarah Powers, Mark W. Scerbo, Matthew Pacailler, Macy Kisiel, Baillie Hirst, Ginger S. Watson, Lauren Hamel, Fred Kron

Modeling, Simulation and Visualization Student Capstone Conference

The present study assessed whether trainees display similar nonverbal and paraverbal behaviors when interacting with a simulated (SP) and virtual patient (VP). Sixty second slices of time following four interactions were rated for the presence and frequency of three nonverbal and paraverbal behaviors. Results revealed that students exhibited fewer behaviors in the VP interaction, possibly due to differences social inhibition or fidelity between the two formats.

The Effects Of School-Based Art Therapy On Depressed Adolescents, Jasmine Nicolas

Nursing | Student Research Posters

Depression in adolescents is associated with deficient behavioral and health outcomes (Fletcher, 2019). Art therapy has been shown to be effective in treating mental health condition such as depression. A student’s academic success heavily depends on treating their depression. Community health nurses can play a vital role in advocating for adequate mental health support to improve a student’s overall well-being and academic success. The literature review contains six articles on the prevalence and impact of depression among adolescents, art therapy as an intervention for improving psychological outcomes and resilience among adolescents, and experiences of adolescent clients in art therapy within …

Children's And Caregivers' Review Of A Guided Imagery Therapy Mobile App Designed To Treat Children With Functional Abdominal Pain Disorders: Leveraging A Mixed Methods Approach With User-Centered Design, John M Hollier, Tiantá A Strickland, C Michael Fordis, Miranda Al Van Tilburg, Robert J Shulman, Debbe Thompson

Faculty, Staff and Students Publications

BACKGROUND: Functional abdominal pain disorders (FAPDs) are highly prevalent and associated with substantial morbidity. Guided imagery therapy (GIT) is efficacious; however, barriers often impede patient access. Therefore, we developed a GIT mobile app as a novel delivery platform.

OBJECTIVE: Guided by user-centered design, this study captured the critiques of our GIT app from children with FAPDs and their caregivers.

METHODS: Children aged 7 to 12 years with Rome IV-defined FAPDs and their caregivers were enrolled. The participants completed a software evaluation, which assessed how well they executed specific app tasks: opening the app, logging in, initiating a session, setting the …

Volume 14, Ireland Seagle, Dalton C. Whitby, Cassandra Poole, Rachel Cannon, Heidi Parker-Combes, Devon G. Shifflett, Antonio Harvey

Incite: The Journal of Undergraduate Scholarship

Table of Contents:

• Introduction: Dr. Amorette Barber
• From the Editor: Dr. Larissa "Kat" Tracy
• From the Designers: Rachel English, Rachel Hanson
• Hungry Like the Wolf: The Wolf as Metaphor in Paramount Network’s Yellowstone: Ireland Seagle
• “Floating Cities”: Illustrating the Commercial and Conservation Conflict of Alaskan Cruise Ship Tourism: Dalton C. Whitby
• What Can You Do When Your Genes are the Enemy? Current Applications of Gene Manipulation and the Associated Ethical Considerations: Cassandra Poole
• La doble cara: un tema romántico en las obras de Larra y Hawthorne: Rachel Cannon
• Resolving a Conflict: How to …

Mechanisms Linking Threat- And Deprivation-Related Childhood Adversity And Depression: The Biopsychosocial Model, Cut N. Kemala, Marijtje L.A. Jongsma, Donny Hendrawan, Eni Becker

Psychological Research on Urban Society

Childhood adversity involves a wide range of negative experiences that pose a serious threat to a child’s wellbeing. It has been consistently shown to predict (chronic) depression in subsequent stages of development, but mechanisms underlying the relationship are still less clear. Moving from a cumulative approach of lumping heterogeneous categories of childhood adversity to a dimensional approach of classifying negative experiences into two major dimensions (threat and deprivation) has facilitated the identification of specific processes by which childhood adversity can predict depression. This review aims to provide an integrative overview of how childhood adversity increases the risk for depression using …