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Full-Text Articles in Medicine and Health Sciences

The Psychosocial Beliefs, Experiences And Expectations Of Children Living With Obesity, Lisa Newson, Nicola Sides, Amineh Rashidi Feb 2024

The Psychosocial Beliefs, Experiences And Expectations Of Children Living With Obesity, Lisa Newson, Nicola Sides, Amineh Rashidi

Research outputs 2022 to 2026

Background: Childhood obesity has been shown to impair psychological health. However, psychological factors are often overlooked in both research evaluations and treatment interventions, and children's perspectives on managing obesity are underexplored. Neglecting psychosocial factors might undermine interventions. This research explored the psychological beliefs, expectations and experiences of children living with obesity (range 7–13) and attending a weight management programme (WMP). Methods: Thirty-four participants (19 females, 15 males, average age 9.5 years) completed a semistructured interview. Recorded interviews were transcribed verbatim and analysed using thematic analysis. Results: Four overarching themes were developed: (1) defining health and self-recognition; (2) external influence; feedback, …


The Ddhd2-Stxbp1 Interaction Mediates Long-Term Memory Via Generation Of Saturated Free Fatty Acids, Isaac O Akefe, Saber H Saber, Benjamin Matthews, Bharat G Venkatesh, Rachel S Gormal, Daniel G Blackmore, Suzy Alexander, Emma Sieriecki, Yann Gambin, Jesus Bertran-Gonzalez, Nicolas Vitale, Yann Humeau, Arnaud Gaudin, Sevannah A Ellis, Alysee A Michaels, Mingshan Xue, Benjamin Cravatt, Merja Joensuu, Tristan P Wallis, Frédéric A Meunier Feb 2024

The Ddhd2-Stxbp1 Interaction Mediates Long-Term Memory Via Generation Of Saturated Free Fatty Acids, Isaac O Akefe, Saber H Saber, Benjamin Matthews, Bharat G Venkatesh, Rachel S Gormal, Daniel G Blackmore, Suzy Alexander, Emma Sieriecki, Yann Gambin, Jesus Bertran-Gonzalez, Nicolas Vitale, Yann Humeau, Arnaud Gaudin, Sevannah A Ellis, Alysee A Michaels, Mingshan Xue, Benjamin Cravatt, Merja Joensuu, Tristan P Wallis, Frédéric A Meunier

Faculty, Staff and Students Publications

The phospholipid and free fatty acid (FFA) composition of neuronal membranes plays a crucial role in learning and memory, but the mechanisms through which neuronal activity affects the brain's lipid landscape remain largely unexplored. The levels of saturated FFAs, particularly of myristic acid (C14:0), strongly increase during neuronal stimulation and memory acquisition, suggesting the involvement of phospholipase A1 (PLA1) activity in synaptic plasticity. Here, we show that genetic ablation of the PLA1 isoform DDHD2 in mice dramatically reduces saturated FFA responses to memory acquisition across the brain. Furthermore, DDHD2 loss also decreases memory performance in reward-based learning and spatial memory …


Study Design And Methods: Us Study To Protect Brain Health Through Lifestyle Intervention To Reduce Risk (Us Pointer), Laura D Baker, Heather M Snyder, Mark A Espeland, Rachel A Whitmer, Miia Kivipelto, Nancy Woolard, Jeffrey Katula, Kathryn V Papp, Jennifer Ventrelle, Sarah Graef, Marcus A Hill, Scott Rushing, Julia Spell, Laura Lovato, Deborah Felton, Benjamin J Williams, Mina Ghadimi Nouran, Rema Raman, Tiia Ngandu, Alina Solomon, Sharon Wilmoth, Maryjo L Cleveland, Jeff D Williamson, Katherine L Lambert, Sarah Tomaszewski Farias, Claire E Day, Christy C Tangney, Darren R Gitelman, Olivia Matongo, Terrianne Reynolds, Valory N Pavlik, Melissa M Yu, Ashley S Alexander, Richard Elbein, Ann Marie Mcdonald, Stephen Salloway, Rena R Wing, Susan Antkowiak, Martha Clare Morris, Maria C Carrillo Feb 2024

Study Design And Methods: Us Study To Protect Brain Health Through Lifestyle Intervention To Reduce Risk (Us Pointer), Laura D Baker, Heather M Snyder, Mark A Espeland, Rachel A Whitmer, Miia Kivipelto, Nancy Woolard, Jeffrey Katula, Kathryn V Papp, Jennifer Ventrelle, Sarah Graef, Marcus A Hill, Scott Rushing, Julia Spell, Laura Lovato, Deborah Felton, Benjamin J Williams, Mina Ghadimi Nouran, Rema Raman, Tiia Ngandu, Alina Solomon, Sharon Wilmoth, Maryjo L Cleveland, Jeff D Williamson, Katherine L Lambert, Sarah Tomaszewski Farias, Claire E Day, Christy C Tangney, Darren R Gitelman, Olivia Matongo, Terrianne Reynolds, Valory N Pavlik, Melissa M Yu, Ashley S Alexander, Richard Elbein, Ann Marie Mcdonald, Stephen Salloway, Rena R Wing, Susan Antkowiak, Martha Clare Morris, Maria C Carrillo

Faculty, Staff and Students Publications

INTRODUCTION: The U.S. study to protect brain health through lifestyle intervention to reduce risk (U.S. POINTER) is conducted to confirm and expand the results of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) in Americans.

METHODS: U.S. POINTER was planned as a 2-year randomized controlled trial of two lifestyle interventions in 2000 older adults at risk for dementia due to well-established factors. The primary outcome is a global cognition composite that permits harmonization with FINGER.

RESULTS: U.S. POINTER is centrally coordinated and conducted at five clinical sites (ClinicalTrials.gov: NCT03688126). Outcomes assessments are completed at baseline and …


Telehealth Treatment For Opioid Use Disorder In Missouri’S Urban And Rural Areas Prior To And Since Covid-19, Aurora Rojo, Rashmi Ghonasgi, Zachary Budesa, Rachel Winograd Jan 2024

Telehealth Treatment For Opioid Use Disorder In Missouri’S Urban And Rural Areas Prior To And Since Covid-19, Aurora Rojo, Rashmi Ghonasgi, Zachary Budesa, Rachel Winograd

Undergraduate Research Symposium

Opioid use disorder (OUD) is a chronic health condition that can be adequately treated when individuals have access to needed services. Telehealth services can be delivered remotely through audio-visual technological communications rather than in-person visits, which can greatly improve care accessibility. Following the onset of COVID-19, there were swift clinical and policy adaptations to promote telehealth services across medical and behavioral health fields. This study aims to identify changes in the frequency of telehealth for OUD treatment in Missouri’s rural and urban counties prior to and since the onset of COVID-19. Chi-square tests and analysis of changes between years and …


Blood Epigenome-Wide Association Studies Of Suicide Attempt In Adults With Bipolar Disorder, Salahudeen Mirza, Camila N C Lima, Alexandra Del Favero-Campbell, Alexandre Rubinstein, Natasha Topolski, Brenda Cabrera-Mendoza, Emese H C Kovács, Hilary P Blumberg, Jenny Gringer Richards, Aislinn J Williams, John A Wemmie, Vincent A Magnotta, Jess G Fiedorowicz, Marie E Gaine, Consuelo Walss-Bass, Joao Quevedo, Jair C Soares, Gabriel R Fries Jan 2024

Blood Epigenome-Wide Association Studies Of Suicide Attempt In Adults With Bipolar Disorder, Salahudeen Mirza, Camila N C Lima, Alexandra Del Favero-Campbell, Alexandre Rubinstein, Natasha Topolski, Brenda Cabrera-Mendoza, Emese H C Kovács, Hilary P Blumberg, Jenny Gringer Richards, Aislinn J Williams, John A Wemmie, Vincent A Magnotta, Jess G Fiedorowicz, Marie E Gaine, Consuelo Walss-Bass, Joao Quevedo, Jair C Soares, Gabriel R Fries

Faculty, Staff and Student Publications

Suicide attempt (SA) risk is elevated in individuals with bipolar disorder (BD), and DNA methylation patterns may serve as possible biomarkers of SA. We conducted epigenome-wide association studies (EWAS) of blood DNA methylation associated with BD and SA. DNA methylation was measured at >700,000 positions in a discovery cohort of n = 84 adults with BD with a history of SA (BD/SA), n = 79 adults with BD without history of SA (BD/non-SA), and n = 76 non-psychiatric controls (CON). EWAS revealed six differentially methylated positions (DMPs) and seven differentially methylated regions (DMRs) between BD/SA and BD/non-SA, with multiple immune-related …


Women’S Comfort With Mobile Applications For Menstrual Cycle Self-Monitoring Following The Overturning Of Roe V. Wade, Gabrielle M. Salvatore, Iris Bercovitz, Danielle Arigo Jan 2024

Women’S Comfort With Mobile Applications For Menstrual Cycle Self-Monitoring Following The Overturning Of Roe V. Wade, Gabrielle M. Salvatore, Iris Bercovitz, Danielle Arigo

College of Science & Mathematics Departmental Research

Background: The overturning of Roe v. Wade in June 2022 has many implications for American women of reproductive age, as well as for researchers focused on women’s health in the United States (U.S.). Personal reproductive health data, such as information collected by menstrual cycle (MC) tracking applications (apps), can now be bought, sold, or accessed by law enforcement to enforce limits on abortion. American women have grown concerned about data privacy and have even deleted MC tracking apps following the overturning of Roe v. Wade. This concern is problematic as these apps may advance our understanding of women’s MC experiences …


Action-Outcome Delays Modulate The Temporal Expansion Of Intended Outcomes, Rohan R Donapati, Anuj Shukla, Raju S Bapi Jan 2024

Action-Outcome Delays Modulate The Temporal Expansion Of Intended Outcomes, Rohan R Donapati, Anuj Shukla, Raju S Bapi

Faculty, Staff and Student Publications

The phenomenon of intentional binding pertains to the perceived connection between a voluntary action and its anticipated result. When an individual intends an outcome, it appears to subjectively extend in time due to a pre-activation of the intended result, particularly evident at shorter action-outcome delays. However, there is a concern that the operationalisation of intention might have led to a mixed interpretation of the outcome expansion attributed to the pre-activation of intention, given the sensitivity of time perception and intentional binding to external cues that could accelerate the realisation of expectations. To investigate the expansion dynamics of an intended outcome, …


Sleep Attitudes As An Indirect Predictor Of Risk For Metabolic Syndrome In First Year College Students, Sophie Hirsch, Hannah Peach, Trudy L. Moore-Harrison, Philip Zendels, Aria Ruggiero, Jane F. Gaultney Jan 2024

Sleep Attitudes As An Indirect Predictor Of Risk For Metabolic Syndrome In First Year College Students, Sophie Hirsch, Hannah Peach, Trudy L. Moore-Harrison, Philip Zendels, Aria Ruggiero, Jane F. Gaultney

Journal of Social, Behavioral, and Health Sciences

Background: Habit formation can be a challenge for first-year students. Research has suggested that regardless of sleep knowledge, favorable sleep attitudes predict better sleep.

Aim: Our aim was to investigate whether sleep attitudes directly or indirectly predicted risk for metabolic syndrome via sleep.

Method: Students completed self-report and physiological measures. Participants wore wristwatches to collect sleep data. Path analyses investigated the direct or indirect effect of sleep attitude on risk for metabolic syndrome via subjective sleep (sleep quality, duration, risk for apnea) and objective sleep (sleep efficiency, duration, subjective risk for apnea).

Results: In our subjective analysis that sleep attitudes …


Identifying Barriers To Mental Health Services Utilization For Black Youth In The United States: A Qualitative Study, Emily Stein, Matthew Hutnyan, Neely Myers Jan 2024

Identifying Barriers To Mental Health Services Utilization For Black Youth In The United States: A Qualitative Study, Emily Stein, Matthew Hutnyan, Neely Myers

SMU Journal of Undergraduate Research

Mental health in Black communities and racial/ethnic disparities in mental health service utilization remain growing concerns. Evidence suggests that psychotic disorders may be more prevalent among Black individuals than white individuals and the Black community faces barriers to care that can negatively influence outcomes. To better understand these barriers, we interviewed mental healthcare providers (n = 11) and Black young adults with first-person experience of psychosis (n = 13) about the experiences of minority young adults with mental health treatment. We analyzed interview transcripts and, consistent with constructivist grounded theory methods, identified iterative patterns across individuals about barriers to care. …


Multiple Timescales Of Temporal Context In Risky Choice: Behavioral Identification And Relationships To Physiological Arousal, Hayley R. Brooks, Peter Sokol-Hessner Jan 2024

Multiple Timescales Of Temporal Context In Risky Choice: Behavioral Identification And Relationships To Physiological Arousal, Hayley R. Brooks, Peter Sokol-Hessner

Psychology: Faculty Scholarship

Context-dependence is fundamental to risky monetary decision-making. A growing body of evidence suggests that temporal context, or recent events, alters risk-taking at a minimum of three timescales: immediate (e.g. trial-by-trial), neighborhood (e.g. a group of consecutive trials), and global (e.g. task-level). To examine context effects, we created a novel monetary choice set with intentional temporal structure in which option values shifted between multiple levels of value magnitude ("contexts") several times over the course of the task. This structure allowed us to examine whether effects of each timescale were simultaneously present in risky choice behavior and the potential mechanistic role of …


Overnight 1-Mg Dst Serum Cortisol In Various Stages Of Chronic Kidney Disease-Normative Data And Underlying Mechanisms, Robin Garg, Saba Samad Memon, Anurag Lila, Vijaya Sarathi, Priyanka Patil, Tukaram Jamale, Sreyashi Bose, Manjiri Karlekar, Virendra Patil, Nalini Shah, Tushar Bandgar Jan 2024

Overnight 1-Mg Dst Serum Cortisol In Various Stages Of Chronic Kidney Disease-Normative Data And Underlying Mechanisms, Robin Garg, Saba Samad Memon, Anurag Lila, Vijaya Sarathi, Priyanka Patil, Tukaram Jamale, Sreyashi Bose, Manjiri Karlekar, Virendra Patil, Nalini Shah, Tushar Bandgar

Faculty, Staff and Student Publications

CONTEXT: Data on the overnight 1 mg-dexamethasone suppression test (ONDST) in renal dysfunction are limited.

OBJECTIVE: We aim to determine the normative range of ONDST cortisol across chronic kidney disease (CKD) stages and reasons for its alteration.

METHODS: Prospectively, 180 CKD (30 each in G2-G5/5D) patients and 30 healthy controls underwent ONDST 8 Am serum cortisol (chemiluminescent immunoassay [CLIA]). In an exploratory cohort, 45 (15 each: G3b/G4, G5/G5D, and healthy controls) individuals' blood biochemistry for basal (8 Am) cortisol and adrenocorticotropin (ACTH), post-ONDST 8 Am dexamethasone, ACTH, cortisol (CLIA and liquid chromatography-tandem mass spectrometry), and 4 Pm cortisol was collected. …


Exploring The Spiritual Alliance Of Maintaining A 5-Acre Tropical Farm Through The Lens Of Occupational Engagement, Jose Rafols, Amy Wagenfeld Jan 2024

Exploring The Spiritual Alliance Of Maintaining A 5-Acre Tropical Farm Through The Lens Of Occupational Engagement, Jose Rafols, Amy Wagenfeld

The Open Journal of Occupational Therapy

Large-scale commercial farmers and small scale “hobby” farmers engage in growing crops for subsistence and survival for themselves, their families, communities, and beyond. Their reverence and passion for farming make them good stewards of both community and world population nourishment. We suggest there may be a collective physical, emotional, and spiritual draw to farming that is interwoven with occupational engagement. Through a personal narrative approach, we reflect on the meaning and the work-focused occupation of farming and specifically how spirituality may be a guiding force that supports engagement despite seemingly insurmountable environmental and personal hardships. With an increasing interest in …


Acculturation And Immigrant Parental Perceptions Concerning Sexual Communication, Kwame Owura Frimpong Jan 2024

Acculturation And Immigrant Parental Perceptions Concerning Sexual Communication, Kwame Owura Frimpong

Journal of Human Services Scholarship and Interprofessional Collaboration

Abstract:

Acculturation presents challenges to many immigrant parents that are adjusting to new lives in the United States. The rationale for conducting this study stemmed from the effects that acculturation can have on the wellbeing of immigrants, adversely affecting their health outcomes. The purpose of this study was to explore the perceptions of Sub-Saharan African immigrant parents concerning having a conversation with their pre-adolescent children about sexuality and sexual practices. Findings revealed communication barriers due to cultural beliefs, cultural taboos, and shame. The findings from this study are beneficial to behavioral healthcare providers that work with immigrant families, parents, and …


Multi-Site Benchmark Classification Of Major Depressive Disorder Using Machine Learning On Cortical And Subcortical Measures, Vladimir Belov, Tracy Erwin-Grabner, Moji Aghajani, Andre Aleman, Alyssa R Amod, Zeynep Basgoze, Francesco Benedetti, Bianca Besteher, Robin Bülow, Christopher R K Ching, Colm G Connolly, Kathryn Cullen, Christopher G Davey, Danai Dima, Annemiek Dols, Jennifer W Evans, Cynthia H Y Fu, Ali Saffet Gonul, Ian H Gotlib, Hans J Grabe, Nynke Groenewold, J Paul Hamilton, Ben J Harrison, Tiffany C Ho, Benson Mwangi, Natalia Jaworska, Neda Jahanshad, Bonnie Klimes-Dougan, Sheri-Michelle Koopowitz, Thomas Lancaster, Meng Li, David E J Linden, Frank P Macmaster, David M A Mehler, Elisa Melloni, Bryon A Mueller, Amar Ojha, Mardien L Oudega, Brenda W J H Penninx, Sara Poletti, Edith Pomarol-Clotet, Maria J Portella, Elena Pozzi, Liesbeth Reneman, Matthew D Sacchet, Philipp G Sämann, Anouk Schrantee, Kang Sim, Jair C Soares, Dan J Stein, Sophia I Thomopoulos, Aslihan Uyar-Demir, Nic J A Van Der Wee, Steven J A Van Der Werff, Henry Völzke, Sarah Whittle, Katharina Wittfeld, Margaret J Wright, Mon-Ju Wu, Tony T Yang, Carlos Zarate, Dick J Veltman, Lianne Schmaal, Paul M Thompson, Roberto Goya-Maldonado, Enigma Major Depressive Disorder Working Group Jan 2024

Multi-Site Benchmark Classification Of Major Depressive Disorder Using Machine Learning On Cortical And Subcortical Measures, Vladimir Belov, Tracy Erwin-Grabner, Moji Aghajani, Andre Aleman, Alyssa R Amod, Zeynep Basgoze, Francesco Benedetti, Bianca Besteher, Robin Bülow, Christopher R K Ching, Colm G Connolly, Kathryn Cullen, Christopher G Davey, Danai Dima, Annemiek Dols, Jennifer W Evans, Cynthia H Y Fu, Ali Saffet Gonul, Ian H Gotlib, Hans J Grabe, Nynke Groenewold, J Paul Hamilton, Ben J Harrison, Tiffany C Ho, Benson Mwangi, Natalia Jaworska, Neda Jahanshad, Bonnie Klimes-Dougan, Sheri-Michelle Koopowitz, Thomas Lancaster, Meng Li, David E J Linden, Frank P Macmaster, David M A Mehler, Elisa Melloni, Bryon A Mueller, Amar Ojha, Mardien L Oudega, Brenda W J H Penninx, Sara Poletti, Edith Pomarol-Clotet, Maria J Portella, Elena Pozzi, Liesbeth Reneman, Matthew D Sacchet, Philipp G Sämann, Anouk Schrantee, Kang Sim, Jair C Soares, Dan J Stein, Sophia I Thomopoulos, Aslihan Uyar-Demir, Nic J A Van Der Wee, Steven J A Van Der Werff, Henry Völzke, Sarah Whittle, Katharina Wittfeld, Margaret J Wright, Mon-Ju Wu, Tony T Yang, Carlos Zarate, Dick J Veltman, Lianne Schmaal, Paul M Thompson, Roberto Goya-Maldonado, Enigma Major Depressive Disorder Working Group

Faculty, Staff and Student Publications

Machine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by small sample sizes, lack of representativeness, data leakage, and/or overfitting. Here, we overcome these limitations with the largest multi-site sample size to date (N = 5365) to provide a generalizable ML classification benchmark of major depressive disorder (MDD) using shallow linear and non-linear models. Leveraging brain measures from standardized ENIGMA analysis pipelines in FreeSurfer, we were able to classify MDD versus healthy controls (HC) with a balanced accuracy …


Craftivism As Inquiry: Holding Life’S Threads, Chloe Watfern, Gaynor Macdonald, Michele Elliot, Lynne Stone, Imelda Gilmore, Manuel Tecson, Najla Turk, Penny Bingham, Jane Mears, Ann Dadich, Barbara Doran, Katherine Boydell, Sarah Wallace Jan 2024

Craftivism As Inquiry: Holding Life’S Threads, Chloe Watfern, Gaynor Macdonald, Michele Elliot, Lynne Stone, Imelda Gilmore, Manuel Tecson, Najla Turk, Penny Bingham, Jane Mears, Ann Dadich, Barbara Doran, Katherine Boydell, Sarah Wallace

The Qualitative Report

In this article, we share insights regarding an arts-based research project where carers of people with dementia conveyed their experiences in cloth. Carers face high rates of mental ill health and burnout, while forming a largely undervalued and unrecognised workforce. Through this project, carers’ knowledge was valued and amplified using an innovative methodology – craftivism. During a series of five workshops in 2021, a small group of carers, researchers and artists gathered online to develop an exhibition of craftivist textile works. They evoked the complexity of their makers’ journeys supporting loved ones at the end of life, finding joy and …


Examining The Effects Of Manualized Suicide Intervention Training On Clinical Psychology Doctoral Trainees: A Quasi-Experimental Trial, Alexander Dorfman M.S. Jan 2024

Examining The Effects Of Manualized Suicide Intervention Training On Clinical Psychology Doctoral Trainees: A Quasi-Experimental Trial, Alexander Dorfman M.S.

Selected Full Text Dissertations, 2011-

Although most clinical psychology doctoral trainees encounter at least one suicidal client over the course of their training (Dexter-Mazza & Freeman, 2003), there is notable variability in the degree of formal suicide risk assessment and intervention training offered across clinical psychology doctoral programs (Monahan & Karver, 2021). Most suicide-related training involves passive (e.g., lectures) rather than active (e.g., role-plays, experiential exercises) training techniques, despite evidence for the effectiveness of the latter in improving clinicians’ skills (Gryglewicz et al., 2020). The Applied Suicide Intervention Skills Training (ASIST) is a manualized, evidence-based training incorporating didactics and role-plays (LivingWorks, 2013; Rodgers, 2010). The …


The Image Of Schizophrenia In Spain's Healthcare System, Meghan Webb Jan 2024

The Image Of Schizophrenia In Spain's Healthcare System, Meghan Webb

CISLA Senior Integrative Projects

Schizophrenia affects thousands of people in Spain and is one of the most serious mental health disorders in existence. Despite its this characteristic, schizophrenia did not always get the proper attention it deserved within the country’s healthcare system. This was largely due to the influence that the Spanish government had, and continues to have, over the healthcare system, giving it the power to choose how the disorder was represented. Therefore, what does that mean for schizophrenia in Spain’s healthcare system today? This essay will explore the ways in which schizophrenia was represented in Spain’s healthcare system through an examination of …


International Consensus On Sleep Problems In Pediatric Palliative Care: Paving The Way, Anna Mercante, Judith Owens, Oliviero Bruni, Magda L. Nunes, Paul Gringras, Shirley Xin Li, Simonetta Papa, Ulrika Kreicbergs, Joanne Wolfe, Boris Zernikow, Ana Lacerda, Franca Benini, Pediatric Sleep And Palliative Care Group Jan 2024

International Consensus On Sleep Problems In Pediatric Palliative Care: Paving The Way, Anna Mercante, Judith Owens, Oliviero Bruni, Magda L. Nunes, Paul Gringras, Shirley Xin Li, Simonetta Papa, Ulrika Kreicbergs, Joanne Wolfe, Boris Zernikow, Ana Lacerda, Franca Benini, Pediatric Sleep And Palliative Care Group

Journal Articles: Munroe-Meyer Institute

OBJECTIVE: Sleep problems constitute a common and heterogeneous complaint in pediatric palliative care (PPC), where they often contribute to disease morbidity and cause additional distress to children and adolescents and their families already facing the burden of life-threatening and life-limiting conditions. Despite the significant impact of sleep problems, clinical evidence is lacking. The application of general pediatric sleep recommendations appears insufficient to address the unique challenges of the PPC dimension in terms of disease variability, duration, comorbidities, complexity of needs, and particular features of sleep problems related to hospice care. Therefore, we initiated an international project aimed at establishing a …


Practice Patterns And Medical Provider Perceptions Of Ketamine In The Treatment Of Psychiatric Disorders: A Nationwide Survey, Amna M. Aslam Jan 2024

Practice Patterns And Medical Provider Perceptions Of Ketamine In The Treatment Of Psychiatric Disorders: A Nationwide Survey, Amna M. Aslam

Theses and Dissertations

Background: Major Depressive Disorder (MDD) significantly impacts society, with a prevalence of 8.4% in the U.S., highlighting the need for effective treatments for treatment-resistant depression (TRD). Ketamine, while not FDA-approved for TRD, shows promise in treating mental health disorders and is used in specialized clinics, though evidence of effectiveness is scarce. Objectives: This study investigates the use of off-label ketamine for TRD and other disorders, focusing on ketamine clinic operations where the drug is administered, treatment methods, patient characteristics, and ketamine's impact on psychiatric care, from providers' perspectives. Methods: The survey was distributed to over 1,000 ketamine providers across the …


Cbt And Me: A Beginning Therapist's Journey Utilizing Client Feedback, Haley Scruggs Jan 2024

Cbt And Me: A Beginning Therapist's Journey Utilizing Client Feedback, Haley Scruggs

Theses and Dissertations--Family Sciences

Cognitive behavioral couple therapy (CBCT) is a model of therapy targeting cognitions, emotional responses, and behavioral interactions between couples experiencing relationship distress. Routine outcome monitoring (ROM) is a tool that clinicians can use to track the progress of their clients in therapy from the perspective of the client. This study aimed to use MFT-PRN, a type of ROM, to gather client progress throughout CBCT treatment. Prototypical change trajectories were created in Microsoft Excel for examination of presenting problem progress, couple satisfaction, and overall relationship functioning. It was found that small data sensitivity affected the trajectories immensely, though ROM outcomes revealed …


Food Accessibility Struggles For College Students With Dietary Restrictions, Ella Schleuning Jan 2024

Food Accessibility Struggles For College Students With Dietary Restrictions, Ella Schleuning

Mahurin Honors College Capstone Experience/Thesis Projects

College is a time when many students experience independence for the first time in their lives. This is the first time they have had to do their laundry on their own, keep their room clean, and maybe most importantly, they are responsible for figuring out where they are going to eat every day, for every meal. The focus of this study is on food accessibility struggles for college students, specifically looking at Western Kentucky University’s (WKU) food on-campus, as well as students with dietary restrictions.

Since college is the first-time students are responsible for their own meals, it can often …


Different Spectrum Of Space Radiation Induced Cognitive Impairments In Radiation-Naïve And Adapted Rats, Richard A. Britten, Arriyam S. Fesshaye, Alyssa Tidmore, Ella N. Tamgue, Paola A. Alvarado-Arriaga Jan 2024

Different Spectrum Of Space Radiation Induced Cognitive Impairments In Radiation-Naïve And Adapted Rats, Richard A. Britten, Arriyam S. Fesshaye, Alyssa Tidmore, Ella N. Tamgue, Paola A. Alvarado-Arriaga

Center for Integrative Neuroscience and Inflammatory Diseases (CINID) Faculty Publications

NASA's decision to resume manned deep space mission, first to the Moon and then Mars, necessitated a detailed assessment of the potential health effects that astronauts may experience on long-duration missions. Multiple studies suggest that there may be significant space radiation (SR)-induced impairment of neurocognitive processes, including advanced executive functions. However, given the multitude of SR-induced changes in the CNS, it is possible that completely different SR-induced sequelae will be induced in previously exposed individuals. Thus, current risk estimates are likely to be pertinent only for the early stages of a deep space mission, and even then only for astronauts …


Why We Come: Investigating Virtual Clubhouse Engagement, Megan H. Price Jan 2024

Why We Come: Investigating Virtual Clubhouse Engagement, Megan H. Price

Wayne State University Dissertations

Only a fraction of individuals living with serious mental illness (SMI) receive adequatetreatment. This study investigates members’ experiences of a virtual adaptation of the Clubhouse model, a psychosocial rehabilitation program. During the COVID-19 lockdowns, the virtual Clubhouse, referred to as virtual programming, was established to provide an alternative to the traditional brick-and-mortar Clubhouse. This qualitative inquiry utilizes a phenomenological approach to understand participant experiences of the virtual model, including factors related to motivation, recovery, and impact. Data was collected through semi-structured interviews with 15 members of a Clubhouse located in a large metropolitan city in the U.S. The interviews sought …


Evaluating The Deductive Competence Of Large Language Models, Spencer M. Seals, Valerie L. Shalin Jan 2024

Evaluating The Deductive Competence Of Large Language Models, Spencer M. Seals, Valerie L. Shalin

Psychology Faculty Publications

The development of highly fluent large language models (LLMs) has prompted increased interest in assessing their reasoning and problem-solving capabilities. We investigate whether several LLMs can solve a classic type of deductive reasoning problem from the cognitive science literature. The tested LLMs have limited abilities to solve these problems in their conventional form. We performed follow up experiments to investigate if changes to the presentation format and content improve model performance. We do find performance differences between conditions; however, they do not improve overall performance. Moreover, we find that performance interacts with presentation format and content in unexpected ways that …


Enhancing Cross-Modal Contextual Congruence For Crowdfunding Success Using Knowledge-Infused Learning, Trilok Padhi, Ugur Kursuncu, Yaman Kumar, Valerie L. Shalin, Lane Peterson Fronczek Jan 2024

Enhancing Cross-Modal Contextual Congruence For Crowdfunding Success Using Knowledge-Infused Learning, Trilok Padhi, Ugur Kursuncu, Yaman Kumar, Valerie L. Shalin, Lane Peterson Fronczek

Psychology Faculty Publications

The digital landscape continually evolves with multimodality, enriching the online experience for users. Creators and marketers aim to weave subtle contextual cues from various modalities into congruent content to engage users with a harmonious message. This interplay of multimodal cues is often a crucial factor in attracting users' attention. However, this richness of multimodality presents a challenge to computational modeling, as the semantic contextual cues spanning across modalities need to be unified to capture the true holistic meaning of the multimodal content. This contextual meaning is critical in attracting user engagement as it conveys the intended message of the brand …


Explore The Relationship Between Birth Order And Level Of Differentiation Of Self, Ruchika Jain Jan 2024

Explore The Relationship Between Birth Order And Level Of Differentiation Of Self, Ruchika Jain

Graduate Research Theses & Dissertations

Family systems theory has played a primary role in the clinical development of family therapy. This study was conducted to explore the relationship between the variables, level of differentiation of self, and birth order. The researcher wanted to understand and explore the applicability of family systems theory in collectivistic cultures like India. Data from 136 participants from India, aged 18-29 was collected. DSI(R) is a self-reporting questionnaire that was filled up by the participants along with their demographic details and birth order. The results inferred that there was no significant relationship between the studied variables, indicating there are other confounding …


Human System Composite Performance Measures: General Systems Performance Theory Insights, Lawrence Disalvi Jan 2024

Human System Composite Performance Measures: General Systems Performance Theory Insights, Lawrence Disalvi

Bioengineering Dissertations - Archive

Composite Performance Measures (CPMs) of human performance are widely employed in applications that range from mundane to life-changing, yet they are frequently presented without explanation or reference to theoretical underpinnings. The conceptual soundness of a widely used CPM approach, based on additive combination of constituent components, has been called into question by Kondraske. He argues the relevance of General Systems Performance Theory (GSPT) and performance capacity envelope concepts when applied to multidimensional CPM measures.

To obtain evidence-based answers to assertions regarding CPM types and rationale employed in medical and non-medical contexts, a Systematic Descriptive Review was conducted. Separately, the GSPT-based …


What Is The Association Between Drinking To Cope With Binge Drinking And Alcohol-Related Blackouts In A College Population?, Adam Hvitfeldt-Matthews, Christina Sheerin Phd, Spit For Science Working Group Jan 2024

What Is The Association Between Drinking To Cope With Binge Drinking And Alcohol-Related Blackouts In A College Population?, Adam Hvitfeldt-Matthews, Christina Sheerin Phd, Spit For Science Working Group

IRBEH/Spit for Science Publications and Presentations

No abstract provided.


Analyzing The Efficacy Of The Nih Emotion Toolbox When Predicting Depression And Anxiety In Individuals With Down Syndrome (Ds), Lauren Hinton, Ruth Brown-Ennis Phd Jan 2024

Analyzing The Efficacy Of The Nih Emotion Toolbox When Predicting Depression And Anxiety In Individuals With Down Syndrome (Ds), Lauren Hinton, Ruth Brown-Ennis Phd

IRBEH/Spit for Science Publications and Presentations

No abstract provided.


Do Adverse Childhood Experiences And Depressive Symptoms Predict Cannabis Use Among College Students Of Color, Llorielle Gregory-Jerome, Arlenis Santana Phd, Chelsea D. Williams Phd, The Spit For Science Working Group, Danielle M. Dick Phd Jan 2024

Do Adverse Childhood Experiences And Depressive Symptoms Predict Cannabis Use Among College Students Of Color, Llorielle Gregory-Jerome, Arlenis Santana Phd, Chelsea D. Williams Phd, The Spit For Science Working Group, Danielle M. Dick Phd

IRBEH/Spit for Science Publications and Presentations

No abstract provided.