Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Rehabilitation (11)
- Aging (10)
- Stroke (9)
- Electromyography (7)
- Exercise (7)
-
- Gait (7)
- Sex differences (7)
- Biomechanics (6)
- Electrical stimulation (6)
- Fatigue (6)
- Gender (6)
- Locomotion (5)
- Osteoarthritis (5)
- Physical therapy (5)
- Wound healing (5)
- Balance (4)
- Knee (4)
- Pain (4)
- Physical activity (4)
- Dynamic contractions (3)
- FMRI (3)
- Fatigability (3)
- Hip flexors (3)
- Muscle fatigue (3)
- Neuromodulation (3)
- Plasticity (3)
- Sleep (3)
- Vastus lateralis muscle (3)
- Voluntary activation (3)
- ACL reconstruction (2)
- Publication Year
- Publication
- Publication Type
Articles 31 - 60 of 191
Full-Text Articles in Medicine and Health Sciences
Disparities In The Allocation Of Inpatient Physical And Occupational Therapy Services For Patients With Covid-19, Sarah Jolley, Amy Nordon-Craft, Melissa P. Wilson, Kyle Ridgeway, Michelle R. Rauzi, Jacob J. Capin, Lauren M. Heery, Jennifer Stevens-Lapsley, Kristine M. Erlandson
Disparities In The Allocation Of Inpatient Physical And Occupational Therapy Services For Patients With Covid-19, Sarah Jolley, Amy Nordon-Craft, Melissa P. Wilson, Kyle Ridgeway, Michelle R. Rauzi, Jacob J. Capin, Lauren M. Heery, Jennifer Stevens-Lapsley, Kristine M. Erlandson
Physical Therapy Faculty Research and Publications
Background
Survivors of the novel coronavirus (COVID-19) experience significant morbidity with reduced physical function and impairments in activities of daily living. The use of in-hospital rehabilitation therapy may reduce long-term impairments.
Objective
To determine the frequency of therapy referral and treatment amongst hospitalized COVID-19 patients, assess for disparities in referral and receipt of therapy, and identify potentially modifiable factors contributing to disparities in therapy allocation.
Design, Setting and Participants
Retrospective cohort study using data collected from the University of Colorado Health Data Compass data warehouse assessing therapy referral rates and estimated delivery based on available administrative billing.
Measurements
Multivariable logistic …
Developing Peri-Operative Rehabilitation In Degenerative Cervical Myelopathy [Ao Spine Recode-Dcm Research Priority Number 6]: An Unexplored Opportunity?, Timothy F. Boerger, Allison S. Hyngstrom, Julio C. Furlan, Sukhvinder Klasi-Ryan, Armin Curt, Brian K. Kwon, Shekar N. Kurpad, Michael G. Fehlings, James S. Harrop, Bizhan Aarabi, Vafa Rahimi-Movaghar, James D. Guest, Jefferson R. Wilson, Benjamin M. Davies, Mark R. N. Kotter, Paul A. Koljonen
Developing Peri-Operative Rehabilitation In Degenerative Cervical Myelopathy [Ao Spine Recode-Dcm Research Priority Number 6]: An Unexplored Opportunity?, Timothy F. Boerger, Allison S. Hyngstrom, Julio C. Furlan, Sukhvinder Klasi-Ryan, Armin Curt, Brian K. Kwon, Shekar N. Kurpad, Michael G. Fehlings, James S. Harrop, Bizhan Aarabi, Vafa Rahimi-Movaghar, James D. Guest, Jefferson R. Wilson, Benjamin M. Davies, Mark R. N. Kotter, Paul A. Koljonen
Physical Therapy Faculty Research and Publications
Study Design
Narrative review.
Objective
Degenerative cervical myelopathy is one of the most frequent impairments of the spinal cord encountered internationally in adults. Currently, surgical decompression is the recommended treatment for people with DCM (PwCM) presenting with moderate to severe symptoms or neurological deficits. However, despite surgical intervention, not all patients make a complete recovery due to the irreversible tissue damage within the spinal cord. The objective of this review is to describe the state and gaps in the current literature on rehabilitation for PwCM and possible innovative rehabilitation strategies.
Methods
Literature search.
Results
In other neurological disorders such as …
Task Effects On Functional Connectivity Measures After Stroke, Kaleb Vinehout, Sheila M. Schindler-Ivens, Jeffrey R. Binder, Brian D. Schmit
Task Effects On Functional Connectivity Measures After Stroke, Kaleb Vinehout, Sheila M. Schindler-Ivens, Jeffrey R. Binder, Brian D. Schmit
Physical Therapy Faculty Research and Publications
Understanding the effect of task compared to rest on detecting stroke-related network abnormalities will inform efforts to optimize detection of such abnormalities. The goal of this work was to determine whether connectivity measures obtained during an overt task are more effective than connectivity obtained during a “resting” state for detecting stroke-related changes in network function of the brain. This study examined working memory, discrete pedaling, continuous pedaling and language tasks. Functional magnetic resonance imaging was used to examine regional and inter-regional brain network function in 14 stroke and 16 control participants. Independent component analysis was used to identify 149 regions …
Laterality Of The Activation Of The Vastus Lateralis Muscle In Females With Parkinson's Disease During The Medication State Compared With Healthy Controls, Yuichi Nishikawa, Kohei Watanabe, Tetsuya Takahashi, Noriaki Maeda, Hirofumi Maruyama, Shinobu Tanaka, Allison S. Hyngstrom
Laterality Of The Activation Of The Vastus Lateralis Muscle In Females With Parkinson's Disease During The Medication State Compared With Healthy Controls, Yuichi Nishikawa, Kohei Watanabe, Tetsuya Takahashi, Noriaki Maeda, Hirofumi Maruyama, Shinobu Tanaka, Allison S. Hyngstrom
Physical Therapy Faculty Research and Publications
This study quantified the laterality of motor unit activation properties in females with Parkinson’s disease during force production (low to high-intensity contraction) using high-density surface electromyography. Sixteen females with Parkinson’s disease (age = ± 7.6 years, disease duration = 4.9 ± 5.1 years) and 14 healthy female subjects (age = 68.6 ± 3.6 years) performed submaximal ramp-up contractions during isometric knee extension. High-density surface electromyography signals were recorded from both vastus lateralis muscles. The level of heterogeneity was calculated in the spatial distribution patterns of the high-density surface electromyography signals to determine the modified entropy, coefficient of variation of the …
Development Of A National Pain Management Competency Profile To Guide Entry-Level Physiotherapy Education In Canada, Nathan Augeard, Geoff Bostick, Jordan Miller, David Walton, Yannick Tousignant-Laflamme, Anne Hudon, André Bussières, Lynn Cooper, Nicol Mcniven, Aliki Thomas, Lesley Singer, Scott M. Fishman, Marie K. Hoeger Bement, Julia M. Hush, Kathleen A. Sluka, Judy Watt-Watson, Lisa C. Carlesso, Sinead Dufour, Roland Fletcher, Katherine Harman, Judith Hunter, Suzy Ngomo, Neil Pearson, Kadija Perreault, Barbara Shay, Peter Stilwell, Susan Tupper, Timothy H. Wideman
Development Of A National Pain Management Competency Profile To Guide Entry-Level Physiotherapy Education In Canada, Nathan Augeard, Geoff Bostick, Jordan Miller, David Walton, Yannick Tousignant-Laflamme, Anne Hudon, André Bussières, Lynn Cooper, Nicol Mcniven, Aliki Thomas, Lesley Singer, Scott M. Fishman, Marie K. Hoeger Bement, Julia M. Hush, Kathleen A. Sluka, Judy Watt-Watson, Lisa C. Carlesso, Sinead Dufour, Roland Fletcher, Katherine Harman, Judith Hunter, Suzy Ngomo, Neil Pearson, Kadija Perreault, Barbara Shay, Peter Stilwell, Susan Tupper, Timothy H. Wideman
Physical Therapy Faculty Research and Publications
Background
National strategies from North America call for substantive improvements in entry-level pain management education to help reduce the burden of chronic pain. Past work has generated a valuable set of interprofessional pain management competencies to guide the education of future health professionals. However, there has been very limited work that has explored the development of such competencies for individual professions in different regions. Developing profession-specific competencies tailored to the local context is a necessary first step to integrate them within local regulatory systems. Our group is working toward this goal within the context of entry-level physiotherapy (PT) programs across …
Knee Cartilage T2 Relaxation Times 3 Months After Acl Reconstruction Are Associated With Knee Gait Variables Linked To Knee Osteoarthritis, Jack R. Williams, Kelsey Neal, Abdulmajeed Alfayyadh, Kendra Lennon, Jacob J. Capin, Ashutosh Khandha, Kurt Manal, Hollis G. Potter, Lynn Snyder-Mackler, Thomas S. Buchanan
Knee Cartilage T2 Relaxation Times 3 Months After Acl Reconstruction Are Associated With Knee Gait Variables Linked To Knee Osteoarthritis, Jack R. Williams, Kelsey Neal, Abdulmajeed Alfayyadh, Kendra Lennon, Jacob J. Capin, Ashutosh Khandha, Kurt Manal, Hollis G. Potter, Lynn Snyder-Mackler, Thomas S. Buchanan
Physical Therapy Faculty Research and Publications
Osteoarthritis development after ACL reconstruction (ACLR) is not well understood. Investigators have examined associations between knee biomechanical alterations and quantitative MRI (qMRI) variables, reflective of cartilage health, 12–60 months following ACLR; however, none have done so early after surgery. As part of an exploratory study, 45 individuals (age, 23 ± 7 years) underwent motion analysis during walking and qMRI 3 months after ACLR. For each limb, peak knee adduction moment (pKAM) and peak knee flexion moment (pKFM) were determined using inverse dynamics and peak medial compartment force was calculated using a neuromusculoskeletal model. T2 relaxation times in the medial …
Safety, Feasibility And Initial Efficacy Of An App-Facilitated Telerehabilitation (After) Programme For Covid-19 Survivors: A Pilot Randomised Study, Jacob J. Capin, Sarah Jolley, Mary Morrow, Meghan Connors, Kristine Hare, Samantha Mawhinney, Amy Nordon-Craft, Michelle R. Rauzi, Sheryl Flynn, Jennifer Stevens-Lapsley, Kristine M. Erlandson
Safety, Feasibility And Initial Efficacy Of An App-Facilitated Telerehabilitation (After) Programme For Covid-19 Survivors: A Pilot Randomised Study, Jacob J. Capin, Sarah Jolley, Mary Morrow, Meghan Connors, Kristine Hare, Samantha Mawhinney, Amy Nordon-Craft, Michelle R. Rauzi, Sheryl Flynn, Jennifer Stevens-Lapsley, Kristine M. Erlandson
Physical Therapy Faculty Research and Publications
Objectives Determine the safety, feasibility and initial efficacy of a multicomponent telerehabilitation programme for COVID-19 survivors.
Design Pilot randomised feasibility study.
Setting In-home telerehabilitation.
Participants 44 participants (21 female, mean age 52 years) discharged home following hospitalisation with COVID-19 (with and without intensive care unit (ICU) stay).
Interventions Participants were block randomised 2:1 to receive 12 individual biobehaviourally informed, app-facilitated, multicomponent telerehabilitation sessions with a licenced physical therapist (n=29) or to a control group (n=15) consisting of education on exercise and COVID-19 recovery trajectory, physical activity and vitals monitoring, and weekly check-ins with study staff. Interventions were 100% remote and …
Phrenic Afferent Activation Modulates Cardiorespiratory Output In The Adult Rat, Kristi A. Streeter, Michael D. Sunshine, Paul W. Davenport, David D. Fuller
Phrenic Afferent Activation Modulates Cardiorespiratory Output In The Adult Rat, Kristi A. Streeter, Michael D. Sunshine, Paul W. Davenport, David D. Fuller
Physical Therapy Faculty Research and Publications
Phrenic afferents project to brainstem areas responsible for cardiorespiratory control and the mid-cervical spinal cord containing the phrenic motor nucleus. Our purpose was to quantify the impact of small- and large-diameter phrenic afferent activation on phrenic motor output. Anesthetized and ventilated rats received unilateral phrenic nerve stimulation while contralateral phrenic motor output and blood pressure were recorded. Twelve currents of 40-Hz inspiratory-triggered stimulation were delivered (20 s on, 5 min off) to establish current response curves. Stimulation pulse width was varied to preferentially activate large-diameter phrenic afferents (narrow pulse width) and recruit small-diameter fibers (wide pulse width). Contralateral phrenic amplitude …
The Role Of Eye Movements, Attention, And Hand Movements On Age-Related Differences In Pegboard Tests, Brittany Heintz Walters, Wendy E. Huddleston, Kristian M. O'Connor, Jinsung Wang, Marie K. Hoeger Bement, Kevin G. Keenan
The Role Of Eye Movements, Attention, And Hand Movements On Age-Related Differences In Pegboard Tests, Brittany Heintz Walters, Wendy E. Huddleston, Kristian M. O'Connor, Jinsung Wang, Marie K. Hoeger Bement, Kevin G. Keenan
Physical Therapy Faculty Research and Publications
Well-documented manual dexterity impairments in older adults may critically depend on the processing of visual information. The purpose of this study was to determine age-related changes in eye and hand movements during commonly used pegboard tests and the association with manual dexterity impairments in older adults. The relationship between attentional deficits and manual dexterity was also assessed. Eye movements and hand kinematics of 20 young (20–38 yr) and 20 older (65–85 yr) adults were recorded during 9-Hole Pegboard, Grooved Pegboard, and a visuospatial dual test. Results were compared with standardized tests of attention (The Test of Everyday Attention and Trail …
Association Of The Psychological Response To The Acl-Sports Training Program And Self-Reported Function At 2 Years After Anterior Cruciate Ligament Reconstruction, Ryan Zarzycki, Jacob J. Capin, Elanna Arhos, Matthew Failla, Angel H. Smith, Lynn Snyder-Mackler
Association Of The Psychological Response To The Acl-Sports Training Program And Self-Reported Function At 2 Years After Anterior Cruciate Ligament Reconstruction, Ryan Zarzycki, Jacob J. Capin, Elanna Arhos, Matthew Failla, Angel H. Smith, Lynn Snyder-Mackler
Physical Therapy Faculty Research and Publications
Background:
Psychological readiness to return to sport has emerged as an important factor associated with outcomes after anterior cruciate ligament reconstruction (ACLR). Psychological factors are potentially modifiable during the course of rehabilitation, and improving them may lead to better outcomes.
Purpose:
To determine whether athletes with a positive psychological response after participation in a neuromuscular training and second injury prevention program had better self-reported function and activity outcomes compared with athletes who did not have a meaningful change.
Study Design:
Cohort study; Level of evidence, 3.
Methods:
After ACLR and the completion of formal rehabilitation, 66 level I/II athletes completed …
Exploring The Pain In Patellofemoral Pain: A Systematic Review And Meta-Analysis Examining Signs Of Central Sensitization, Kemery J. Sigmund, Marie K. Hoeger Bement, Jennifer E. Earl-Boehm
Exploring The Pain In Patellofemoral Pain: A Systematic Review And Meta-Analysis Examining Signs Of Central Sensitization, Kemery J. Sigmund, Marie K. Hoeger Bement, Jennifer E. Earl-Boehm
Physical Therapy Faculty Research and Publications
Background
Patellofemoral pain (PFP) has high recurrence rates and minimal long-term treatment success. Central sensitization refers to dysfunctional pain modulation that occurs when nociceptive neurons become hyperresponsive. Researchers in this area of PFP have been increasingly productive in the past decade.
Objective
To determine whether evidence supports manifestations of central sensitization in individuals with PFP.
Data Sources
We searched MeSH terms for quantitative sensory testing (QST) pressure pain thresholds (PPTs), conditioned pain modulation (CPM), temporal summation, sensitization, hyperalgesia, and anterior knee pain or PFP in PubMed, SPORTDiscus, CINAHL, Academic Search Complete, and EBSCOhost.
Study Selection
Peer-reviewed studies that were written …
Gait Mechanics Are Influenced By Quadriceps Strength, Age, And Sex After Total Knee Arthroplasty, Jesse C. Christensen, Jacob J. Capin, Lauren A. Hinrichs, Moiyad Aljehani, Jennifer E. Stevens-Lapsley, Joseph A. Zeni
Gait Mechanics Are Influenced By Quadriceps Strength, Age, And Sex After Total Knee Arthroplasty, Jesse C. Christensen, Jacob J. Capin, Lauren A. Hinrichs, Moiyad Aljehani, Jennifer E. Stevens-Lapsley, Joseph A. Zeni
Physical Therapy Faculty Research and Publications
Although most patients are satisfied with outcomes after total knee arthroplasty (TKA), many retain preoperative altered gait mechanics. Identifying patient characteristics associated with gait mechanics will improve rehabilitation strategies and enhance our understanding of movement disorders. Therefore, the purpose of this study was to identify which patient characteristics are related to gait mechanics in the surgical limb during walking post-TKA. Patient characteristics included age, body mass, sex, quadriceps strength, self-reported function, and knee pain. General linear regression was used to compare patient characteristics associated with gait mechanics, after controlling for gait speed, functional capacity and time from surgery. We tested …
Electroencephalography Resting-State Networks In People With Stroke, Dylan B. Snyder, Brian D. Schmit, Allison S. Hyngstrom, Scott A. Beardsley
Electroencephalography Resting-State Networks In People With Stroke, Dylan B. Snyder, Brian D. Schmit, Allison S. Hyngstrom, Scott A. Beardsley
Biomedical Engineering Faculty Research and Publications
Introduction
The purpose of this study was to characterize resting-state cortical networks in chronic stroke survivors using electroencephalography (EEG).
Methods
Electroencephalography data were collected from 14 chronic stroke and 11 neurologically intact participants while they were in a relaxed, resting state. EEG power was normalized to reduce bias and used as an indicator of network activity. Correlations of orthogonalized EEG activity were used as a measure of functional connectivity between cortical regions.
Results
We found reduced cortical activity and connectivity in the alpha (p < .05; p = .05) and beta (p < .05; p = .03) bands after stroke while connectivity …
An Updated Systematic Review Of Cost-Effectiveness Analyses Of Drugs For Osteoporosis, Nannan Li, Dennis Cornelissen, Stuart Silverman, Daniel Pinto, Lei Si, Ingrid Kremer, Sandrine Bours, Robin De Bot, Annelies Boonen, Silva Evers, Joop Van Den Bergh, Jean-Yves Reginster, Mickaël Hiligsmann
An Updated Systematic Review Of Cost-Effectiveness Analyses Of Drugs For Osteoporosis, Nannan Li, Dennis Cornelissen, Stuart Silverman, Daniel Pinto, Lei Si, Ingrid Kremer, Sandrine Bours, Robin De Bot, Annelies Boonen, Silva Evers, Joop Van Den Bergh, Jean-Yves Reginster, Mickaël Hiligsmann
Physical Therapy Faculty Research and Publications
Background
Considering the heavy economic burden of osteoporotic fractures, the limits of healthcare resources, and the recent availability of new anti-osteoporosis drugs, there is continuing interest in economic evaluation studies of osteoporosis management strategies.
Objectives
This study aims to (1) systematically review recent economic evaluations of drugs for osteoporosis and (2) to apply an osteoporosis-specific guideline to critically appraise them.
Methods
A literature search was undertaken using PubMed, EMBASE, National Health Service Economic Evaluation database, and the Cost-Effectiveness Analysis Registry to identify original articles containing economic evaluations of anti-osteoporosis drugs, published between 1 July, 2013 and 31 December, 2019. A …
Ampakines Stimulate Phrenic Motor Output After Cervical Spinal Cord Injury, L. B. Wollman, Kristi A. Streeter, A. F. Fusco, E. J. Gonzalez-Rothi, M. S. Sandhu, J. J. Greer, D. D. Fuller
Ampakines Stimulate Phrenic Motor Output After Cervical Spinal Cord Injury, L. B. Wollman, Kristi A. Streeter, A. F. Fusco, E. J. Gonzalez-Rothi, M. S. Sandhu, J. J. Greer, D. D. Fuller
Physical Therapy Faculty Research and Publications
Activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors increases phrenic motor output. Ampakines are a class of drugs that are positive allosteric modulators of AMPA receptors. We hypothesized that 1) ampakines can stimulate phrenic activity after incomplete cervical spinal cord injury (SCI), and 2) pairing ampakines with brief hypoxia could enable sustained facilitation of phrenic bursting. Phrenic activity was recorded ipsilateral (IL) and contralateral (CL) to C2 spinal cord hemisection (C2Hx) in anesthetized adult rats. Two weeks after C2Hx, ampakine CX717 (15 mg/kg, i.v.) increased IL (61 ± 46% baseline, BL) and CL burst amplitude (47 ± 26%BL) in 8 of 8 …
Clinical Update For Physical Therapists: Coagulopathy And Covid-19, Kathleen M. Lukaszewicz, Ellen Hillegass, Michael Puthoff, A. Kate Macphedran
Clinical Update For Physical Therapists: Coagulopathy And Covid-19, Kathleen M. Lukaszewicz, Ellen Hillegass, Michael Puthoff, A. Kate Macphedran
Physical Therapy Faculty Research and Publications
Physical therapists have a unique role in both prevention of venous thromboembolism (VTE) through the promotion of early mobility and physical activity and diagnosis through discovery of signs and symptoms of VTE. This Perspective updates clinicians on the latest information regarding pathophysiology of coagulopathy associated with COVID-19 and applies VTE clinical practice guidelines to COVID-19 in order to provide guidance on physical therapist management.
Two Weeks Of Remote Ischemic Conditioning Improves Brachial Artery Flow Mediated Dilation In Chronic Stroke Survivors, Allison Hyngstrom, Jennifer Nguyen, Michael Wright, Sergey Tarima, Brian Schmit, David D. Gutterman, Matthew J. Durand
Two Weeks Of Remote Ischemic Conditioning Improves Brachial Artery Flow Mediated Dilation In Chronic Stroke Survivors, Allison Hyngstrom, Jennifer Nguyen, Michael Wright, Sergey Tarima, Brian Schmit, David D. Gutterman, Matthew J. Durand
Physical Therapy Faculty Research and Publications
Many stroke survivors have reduced cardiorespiratory fitness as a result of their stroke. Ischemic conditioning (IC) is a noninvasive, cost-effective, easy-to-administer intervention that can be performed at home and has been shown to improve both motor function in stroke survivors and vascular endothelial function in healthy individuals. In this study, we examined the effects of 2 wk of remote IC (RIC) on brachial artery flow mediated dilation (FMD) in chronic stroke survivors. We hypothesized that FMD would be improved following RIC compared with a sham RIC control group. This was a prospective, randomized, double-blinded, controlled study. Twenty-four chronic stroke survivors …
Experimental & Simulation Approaches To Study Neuromuscular Control In People With Chronic Ankle Instability, Hoon Kim
Dissertations (1934 -)
Ankle sprains are among the most common musculoskeletal injuries, and up to 70% of people who sprain their ankles develop chronic ankle instability (CAI). Moreover, people who develop CAI have a significantly higher risk of developing ankle osteoarthritis. Recent research has identified neuromuscular deficits that may be responsible for the high recurrence rates of ankle sprains and for the progression towards ankle osteoarthritis in people with CAI. Unfortunately, current rehabilitation strategies are not completely successful because the mechanisms responsible for these deficits are not fully elucidated. Therefore, the purpose of this dissertation was to investigate individual muscle forces and force …
Pain Modulatory Effects Of Exercise In Chronic Pain, Giovanni Berardi
Pain Modulatory Effects Of Exercise In Chronic Pain, Giovanni Berardi
Dissertations (1934 -)
Exercise training is recommended as a first-line treatment in the management of fibromyalgia due to its ability to improve symptoms and function. However, many with fibromyalgia report limited tolerance to exercise due to exacerbation of pain and fatigue during and following participation of a single bout of exercise. The purpose of this dissertation was to determine the influence of contraction type on local and systemic experimental pain sensitivity, performance fatigue, and perceived pain and fatigue during exercise and through recovery in people with and without fibromyalgia.Experimental and perceived pain were measured before and after a single bout of submaximal intermittent …
The Influence Of Autonomic Function On Pain Modulation Before And After Exercise And Cognitive Task In Fibromyalgia, Abdulaziz Awali
The Influence Of Autonomic Function On Pain Modulation Before And After Exercise And Cognitive Task In Fibromyalgia, Abdulaziz Awali
Dissertations (1934 -)
Fibromyalgia (FM) is a chronic pain condition characterized by widespread pain. People with FM have alterations in autonomic function compared to healthy individuals. Exercise can decrease pain in people with FM, however some people with FM experience pain exacerbation when initiating exercise. Whether variability in pain at rest and following exercise is related to altered autonomic function, including the potential implications with other stressful events such as mental math, is not known. This dissertation aimed at investigating: 1) the relation between cardiovascular autonomic function and central pain facilitation and inhibition, measured by temporal summation of pain (TS) and conditioned pain …
A Discrete-Choice Experiment To Assess Patients’ Preferences For Osteoarthritis Treatment: An Esceo Working Group, Mickael Hiligsmann, Elaine Dennison, Charlotte Beaudart, Gabriel Herrero-Beaumont, Jaime Branco, Olivier Bruyère, Philip G. Conaghan, Cyrus Cooper, Nasser Al-Daghri, Famida Jiwa, Willem Lems, Daniel Pinto, René Rizzoli, Thierry Thomas, Daniel Uebelhart, Nicolas Veronese, Jean-Yves Reginster
A Discrete-Choice Experiment To Assess Patients’ Preferences For Osteoarthritis Treatment: An Esceo Working Group, Mickael Hiligsmann, Elaine Dennison, Charlotte Beaudart, Gabriel Herrero-Beaumont, Jaime Branco, Olivier Bruyère, Philip G. Conaghan, Cyrus Cooper, Nasser Al-Daghri, Famida Jiwa, Willem Lems, Daniel Pinto, René Rizzoli, Thierry Thomas, Daniel Uebelhart, Nicolas Veronese, Jean-Yves Reginster
Physical Therapy Faculty Research and Publications
Objective
To evaluate the preferences of patients with osteoarthritis for treatment.
Methods
A discrete-choice experiment was conducted among adult OA patients who were presented with 12 choice sets of two treatment options and asked in each to select the treatment they would prefer. Based on literature reviews, expert consultation, patient survey and expert meeting, treatment options were characterized by seven attributes: improvement in pain, improvement in walking, ability to manage domestic activities, ability to manage social activities, improvement in overall energy and well-being, risk of moderate/severe side effects and impact on disease progression. Random parameters logit model was used to …
Direct Healthcare Costs Associated With Oligoarticular Juvenile Idiopathic Arthritis At A Single Center, Amit Thakral, Daniel Pinto, Michael Miller, Megan L. Curran, Marisa Klein-Gitelman, Dustin D. French
Direct Healthcare Costs Associated With Oligoarticular Juvenile Idiopathic Arthritis At A Single Center, Amit Thakral, Daniel Pinto, Michael Miller, Megan L. Curran, Marisa Klein-Gitelman, Dustin D. French
Physical Therapy Faculty Research and Publications
Oligoarticular juvenile idiopathic arthritis (JIA) is a common disease in pediatric rheumatology. The management of oligoarticular JIA can result in a considerable economic burden. This study is a four-year, retrospective cost identification analysis performed to determine the annual direct cost of care for patients with oligoarticular JIA and possible predictive clinical factors. Direct healthcare costs were defined as those associated with office visits, laboratory studies, hospital admissions, joint injections, medications, infusions, radiology tests, and emergency room visits. Disease characteristics and patient information included ANA status, gender, age at diagnosis, duration from diagnosis to initial visit during the study period, and …
Submaximal Isometric Force Steadiness In People With Multiple Sclerosis Under Single And Dual Task Conditions, Sheri Bunyan
Submaximal Isometric Force Steadiness In People With Multiple Sclerosis Under Single And Dual Task Conditions, Sheri Bunyan
Dissertations (1934 -)
Activities of daily living require steady, non-fatiguing, isometric muscular contractions to maintain postural control and stabilize body segments to facilitate interaction with the environment. Furthermore, typical activities often require simultaneous performance of cognitive and motor tasks. This may challenge people with multiple sclerosis, a chronic neurodegenerative disease of the central nervous system associated with motor and cognitive impairments. Despite functional relevance, isometric force steadiness in both the upper and lower extremities has not been explored in this population. Additionally, dual task experiments in multiple sclerosis have primarily used gait, a dynamic activity, as the motor task. Thus, the purpose of …
Temporal Aspects Of Endogenous Pain Modulation During A Noxious Stimulus Prolonged For 1 Day, Marie K. Hoeger Bement, Kristian K. Petersen, Line B. Sørensen, Hjalte H. Andersen, Thomas Graven-Nielsen
Temporal Aspects Of Endogenous Pain Modulation During A Noxious Stimulus Prolonged For 1 Day, Marie K. Hoeger Bement, Kristian K. Petersen, Line B. Sørensen, Hjalte H. Andersen, Thomas Graven-Nielsen
Physical Therapy Faculty Research and Publications
Background
This study investigated (a) if a prolonged noxious stimulus (24‐hr topical capsaicin) in healthy adults would impair central pain inhibitory and facilitatory systems measured as a reduction in conditioned pain modulation (CPM) and enhancement of temporal summation of pain (TSP) and (b) if acute pain relief or exacerbation (cooling and heating the capsaicin patch) during the prolonged noxious stimulus would affect central pain modulation.
Methods
Twenty‐eight participants (26.2 ± 1.0 years; 12 women) wore a transdermal 8% capsaicin patch on the forearm for 24 hr. Data were collected at baseline (Day 0), 1 hr, 3 hr, Day 1 (post‐capsaicin …
Energy Cost Of Slow And Normal Gait Speeds In Low And Normally Functioning Adults, Taylor W. Rowley, Chi Cho, Ann M. Swartz, John Staudenmayer, Allison S. Hyngstrom, Kevin G. Keenan, Whitney A. Welch, Scott J. Strath
Energy Cost Of Slow And Normal Gait Speeds In Low And Normally Functioning Adults, Taylor W. Rowley, Chi Cho, Ann M. Swartz, John Staudenmayer, Allison S. Hyngstrom, Kevin G. Keenan, Whitney A. Welch, Scott J. Strath
Physical Therapy Faculty Research and Publications
Objective
Slow walking speed paired with increased energy cost is a strong predictor for mortality and disability in older adults but has yet to be examined in a heterogeneous sample (ie, age, sex, disease status). The aim of this study was to examine energy cost of slow and normal walking speeds among low- and normal-functioning adults.
Design
Adults aged 20–90 yrs were recruited for this study. Participants completed a 10-m functional walk test at a self-selected normal walking speed and were categorized as low functioning or normal functioning based on expected age- and sex-adjusted average gait speed. Participants completed two …
The Impact Of Isometric Exercise On Somatosensory Processing In People With Or Without Chronic Pain, Ali Mohammed Alsouhibani
The Impact Of Isometric Exercise On Somatosensory Processing In People With Or Without Chronic Pain, Ali Mohammed Alsouhibani
Dissertations (1934 -)
Despite an increase in our understanding of the pathomechanisms of chronic pain and the advancement of new treatments, pharmacological management of chronic pain remains poor. This presents the need for non-pharmacological treatments and understanding their efficacy and mechanisms in managing pain. The purpose of this dissertation was to examine the effects of isometric exercise on the somatosensory system and other biopsychosocial aspects related to pain in individuals with and without fibromyalgia. The first aim was to determine whether isometric exercise improves pain inhibitory mechanisms and vibration sense. The second aim was to determine what biopsychosocial factors influence pain relief following …
Practical Guidance For Engaging Patients In Health Research, Treatment Guidelines And Regulatory Processes: Results Of An Expert Group Meeting Organized By The World Health Organization (Who) And The European Society For Clinical And Economic Aspects Of Osteoporosis, Osteoarthritis And Musculoskeletal Diseases (Esceo), Maarten De Wit, Cyrus Cooper, Peter Tugwell, Nathalie Bere, John Kirwan, Philip G. Conaghan, Charlotte Roberts, Isabelle Aujoulat, Nasser Al-Daghri, Islene Arajujo De Carvalho, Mary Barker, Nicola Bedlington, Maria Luisa Brandi, Olivier Bruyère, Nansa Burlett, Philippe Halbout, Mickaël Hiligsmann, Famida Jiwa, John A. Kanis, Andrea Laslop, Wendy Lawrence, Daniel Pinto, Concepción Prieto Yerro, Véronique Rabenda, René Rizzoli, Marieke Scholte-Voshaar, Mila Vlaskovska, Jean-Yves Reginster
Practical Guidance For Engaging Patients In Health Research, Treatment Guidelines And Regulatory Processes: Results Of An Expert Group Meeting Organized By The World Health Organization (Who) And The European Society For Clinical And Economic Aspects Of Osteoporosis, Osteoarthritis And Musculoskeletal Diseases (Esceo), Maarten De Wit, Cyrus Cooper, Peter Tugwell, Nathalie Bere, John Kirwan, Philip G. Conaghan, Charlotte Roberts, Isabelle Aujoulat, Nasser Al-Daghri, Islene Arajujo De Carvalho, Mary Barker, Nicola Bedlington, Maria Luisa Brandi, Olivier Bruyère, Nansa Burlett, Philippe Halbout, Mickaël Hiligsmann, Famida Jiwa, John A. Kanis, Andrea Laslop, Wendy Lawrence, Daniel Pinto, Concepción Prieto Yerro, Véronique Rabenda, René Rizzoli, Marieke Scholte-Voshaar, Mila Vlaskovska, Jean-Yves Reginster
Physical Therapy Faculty Research and Publications
There is increasing emphasis on patient-centred research to support the development, approval and reimbursement of health interventions that best meet patients’ needs. However, there is currently little guidance on how meaningful patient engagement may be achieved. An expert working group, representing a wide range of stakeholders and disciplines, was convened by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the World Health Organization (WHO). Through a structured, collaborative process the group generated practical guidance to facilitate optimal patient engagement in clinical development and regulatory decisions. Patient engagement is a relational process. The …
Practical Guidance For Engaging Patients In Health Research, Treatment Guidelines And Regulatory Processes: Results Of An Expert Group Meeting Organized By The World Health Organization (Who) And The European Society For Clinical And Economic Aspects Of Osteoporosis, Osteoarthritis And Musculoskeletal Diseases (Esceo), Maarten De Wit, Cyrus Cooper, Peter Tugwell, Nathalie Bere, John Kirwan, Philip G. Conaghan, Charlotte Roberts, Isabelle Aujoulat, Nasser Al-Daghri, Islene Arajujo De Carvalho, Mary Barker, Nicola Bedlington, Maria Luisa Brandi, Olivier Bruyère, Nansa Burlett, Philippe Halbout, Mickaël Hiligsmann, Famida Jiwa, John A. Kanis, Andrea Laslop, Wendy Lawrence, Daniel Pinto, Concepción Prieto Yerro, Véronique Rabenda, René Rizzoli, Marieke Scholte-Voshaar, Mila Vlaskovska, Jean-Yves Reginster
Practical Guidance For Engaging Patients In Health Research, Treatment Guidelines And Regulatory Processes: Results Of An Expert Group Meeting Organized By The World Health Organization (Who) And The European Society For Clinical And Economic Aspects Of Osteoporosis, Osteoarthritis And Musculoskeletal Diseases (Esceo), Maarten De Wit, Cyrus Cooper, Peter Tugwell, Nathalie Bere, John Kirwan, Philip G. Conaghan, Charlotte Roberts, Isabelle Aujoulat, Nasser Al-Daghri, Islene Arajujo De Carvalho, Mary Barker, Nicola Bedlington, Maria Luisa Brandi, Olivier Bruyère, Nansa Burlett, Philippe Halbout, Mickaël Hiligsmann, Famida Jiwa, John A. Kanis, Andrea Laslop, Wendy Lawrence, Daniel Pinto, Concepción Prieto Yerro, Véronique Rabenda, René Rizzoli, Marieke Scholte-Voshaar, Mila Vlaskovska, Jean-Yves Reginster
Physical Therapy Faculty Research and Publications
There is increasing emphasis on patient-centred research to support the development, approval and reimbursement of health interventions that best meet patients’ needs. However, there is currently little guidance on how meaningful patient engagement may be achieved. An expert working group, representing a wide range of stakeholders and disciplines, was convened by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the World Health Organization (WHO). Through a structured, collaborative process the group generated practical guidance to facilitate optimal patient engagement in clinical development and regulatory decisions. Patient engagement is a relational process. The …
The Effect Of A Portable Electrical Muscle Stimulation Device At Home On Muscle Strength And Activation Patterns In Locomotive Syndrome Patients: A Randomized Control Trial, Yuichi Nishikawa, Kohei Watanabe, Shuhei Kawade, Tetsuya Takahashi, Hiroaki Kimura, Hirofumi Maruyama, Allison S. Hyngstrom
The Effect Of A Portable Electrical Muscle Stimulation Device At Home On Muscle Strength And Activation Patterns In Locomotive Syndrome Patients: A Randomized Control Trial, Yuichi Nishikawa, Kohei Watanabe, Shuhei Kawade, Tetsuya Takahashi, Hiroaki Kimura, Hirofumi Maruyama, Allison S. Hyngstrom
Physical Therapy Faculty Research and Publications
The aim of the present study was to quantify the effect of electrical muscle stimulation (EMS) intervention using a portable device on muscle strength and activation patterns in locomotive syndrome. Nineteen women were randomly assigned to the intervention group (n = 10; age = 71–82 years) and control group (n = 9; age = 70–84 years). Participants in the intervention group used a portable EMS device to stimulate the bilateral quadriceps muscles for 8 weeks (23 min/5 days/week). To understand the effects of EMS, the following measurements were made at baseline, 8 weeks, and 12 weeks: locomotive syndrome assessment score, …
Does Weight Status Impact Metabolic Health In Adolescents When Controlling For Physical Fitness?, Stacy Stolzman, Joseph Skelton, April L. Harkins, Marie K. Hoeger Bement
Does Weight Status Impact Metabolic Health In Adolescents When Controlling For Physical Fitness?, Stacy Stolzman, Joseph Skelton, April L. Harkins, Marie K. Hoeger Bement
Physical Therapy Faculty Research and Publications
Purpose:
To determines whether adolescents who are fit with overweight/obesity are similar in their metabolic profile to adolescents who are fit and normal weight.
Methods:
Adolescents participated in 3 sessions: (1) resting vitals and anthropometrics; (2) maximal aerobic treadmill test () to determine physical fitness; and (3) dual-energy x-ray absorptiometry and fasting laboratory draw for analysis of insulin, glucose, high-density lipoprotein, triglycerides, and C-reactive protein.
Results:
Of the 30 fit adolescents who are normal weight and 16 adolescents who are fit and overweight/obese (OW/OB), metabolic syndrome was apparent in 1 adolescent who are normal weight and 4 adolescents who are …