Medicine and Health Sciences Commons^™

Unlv Title Iii Aanapisi & Mcnair Scholars Institute Research Journal, Nir Herscovici, Joyce Hsu, Matthew Khumnark, Joy Lamug, Jeong Lim Lee, Kendall Lyons, Andrea Mandril, Niroshini Moodley, Eric Ng, Timothy Ogburn, Andrew A. Ortiz, Emily Khanh Pham, Nha Trang Vivian Sam, Devlynn Scarpati, Olivia Tsang, Termaine Antonio Turner Ii, Pang Kou Vang, Kanisha Wilson, Shannon Zayas, Claudia Chiang-Lopez, Victoria Copeland, Andrea Darby, Bridgett Giordmaina, Briceida Hernandez-Toledo, Mark Larubio, Ana Lesquives, Yessenia Madrigal, Summer Millwood, Angel Mims, Blaine Pennock, Katie Randolph, Amber K. Stephens, Sarah Werman, Eben-Ezer Arias-Garcia, Ernesto H. Bedoy, Royale Cannon, Irma De Santiago, Lorraine Louise K. Francisco, Imani A. Gayden, Jeffrey Gonzalez, Isaiah Shornell Henry, Ashley C. Lee, Marielle Leo, Elizabeth Ochoa, Bernajane Palisoc, Sean Tanzey, Howard Yanxon

McNair Journal

Journal articles based on research conducted by undergraduate students in the AANAPISI and McNair Scholars Programs

Table of Contents

About AANAPISI

Biography of Dr. Ronald E. McNair

Statements

Dr. Len Jessup, UNLV President

Dr. Juanita P. Fain, Vice President for Student Affairs

Dr. William W. Sullivan, Associate Vice President for Retention and Outreach

Mr. Keith Rogers, Deputy Executive Director of the Center for Academic Enrichment and Outreach

Title III AANAPISI and McNair Scholars Institute Staff

Ms. Terri Bernstein, Director for College Programs

Dr. Matthew Della Sala, Assistant Director for Undergraduate Research

Optimized Multilayer Perceptron With Dynamic Learning Rate To Classify Breast Microwave Tomography Image, Chulwoo Pack

Electronic Theses and Dissertations

Most recently developed Computer Aided Diagnosis (CAD) systems and their related research is based on medical images that are usually obtained through conventional imaging techniques such as Magnetic Resonance Imaging (MRI), x-ray mammography, and ultrasound. With the development of a new imaging technology called Microwave Tomography Imaging (MTI), it has become inevitable to develop a CAD system that can show promising performance using new format of data. The platform can have a flexibility on its input by adopting Artificial Neural Network (ANN) as a classifier. Among the various phases of CAD system, we have focused on optimizing the classification phase …

Myeloperoxidase-Mediated Protein Lysine Oxidation Generates 2- Aminoadipic Acid And Lysine Nitrile In Vivo, Hongqiao Lin, Bruce S. Levison, Jennifer A. Buffa, Ying Huang, Xiaoming Fu, Zeneng Wang, Valentin Gogonea, Joseph A. Didonato, Stanley L. Hazen

Chemistry Faculty Publications

Recent studies reveal 2-aminoadipic acid (2-AAA) is both elevated in subjects at risk for diabetes and mechanistically linked to glucose homeostasis. Prior studies also suggest enrichment of protein-bound 2-AAA as an oxidative post-translational modification of lysyl residues in tissues associated with degenerative diseases of aging. While in vitro studies suggest redox active transition metals or myeloperoxidase (MPO) generated hypochlorous acid (HOCl) may produce protein-bound 2-AAA, the mechanism(s) responsible for generation of 2- AAA during inflammatory diseases are unknown. In initial studies we observed that traditional acid- or basecatalyzed protein hydrolysis methods previously employed to measure tissue 2-AAA can artificially generate …

Examining The Activities, Effectiveness, And Contribution Of Local Health Departments Using A National Longitudinal Survey Of Public Health Systems, Lava R. Timsina

Theses and Dissertations--Epidemiology and Biostatistics

Health services research and public health services and systems research in the past have contributed to a strong foundation of evidence-based progress in organizing, financing, and delivering medical care and public health strategies across the United States. The purpose of this dissertation was to examine disparities in public health systems and in the delivery of population health services in communities served by these systems using nationally representative data from the National Longitudinal Survey of Local Public Health Systems (1998, 2006, 2012, and 2014).

Data from the 1998 cohort of 497 local health jurisdictions serving at least 100,000 residents, and from …

A Multi-Model Approach In Developing An Intelligent Assistant For Diagnosis Recommendation In Clinical Health Systems, Christian E. Pulmano, Ma. Regina Justina E. Estuar

Department of Information Systems & Computer Science Faculty Publications

Clinical health information systems capture massive amounts of unstructured data from various health and medical facilities. This study utilizes unstructured patient clinical text data to develop an intelligent assistant that can identify possible related diagnoses based on a given text input. The approach applies a one-vs-rest binary classification technique wherein given an input text data, it is identified whether it can be positively or negatively classified for a given diagnosis. Multi-layer Feed-Forward Neural Network models were developed for each individual diagnosis case. The task of the intelligent assistant is to iterate over all the different models and return those that …

How Leaders Market And Commercialize Healthcare Technology Innovation, Roxie Mooney, Rocky J. Dwyer Dr.

Walden Faculty and Staff Publications

This study investigates what strategies technology development marketing leaders utilized to commercialize a new product innovation in the healthcare market. Analysis of data generated 3 major themes: strategies implemented during the prelaunch phase, strategies implemented during the pilot customer phase, and strategies implemented in the broader market launch phase of the CoI process. Findings from this study may contribute to maximizing commercial success and the diffusion of new product innovations in healthcare, which might lead to better patient outcomes and enhanced ways of practicing medicine.

Association Between Hiv And Violence Among Female Commercial Sex Workers In Ukraine : Analysis Of Bio-Behavioral Surveillance Conducted In 2015-2016, Ganna Momotyuk

Legacy Theses & Dissertations (2009 - 2024)

A cross-sectional analysis investigated the association between HIV and violence in female commercial sex workers (FCSW) in Ukraine between 10/2015 and 01/2016. Methods: 3,885 FCSW from a total of 4,300 were questioned about behavioral and social demographics and tested for HIV in mobile testing van. Results: of the 3,885 respondents, 5.89% were HIV positive, and 47.00% had experienced violence. We tested for and found that drug use was an effect modifier for the association between HIV and violence. Analyses were stratified by injecting drug use and no injecting drug use. High risk for HIV was found in the non-IDU stratum …

Investigating Secondary Structure Features Of Yap1 Protein Fragments Using Molecular Dynamics (Md) And Steered Molecular Dynamics (Smd) Simulations, Ferdiemar Cardenas Guinto Jr.

University of the Pacific Theses and Dissertations

Molecular dynamics (MD) is a powerful tool that can be applied to protein folding and protein structure. MD allows for the calculation of movement, and final position, of atoms in a biomolecule. These movements can be used to investigate the pathways that allow proteins to fold into energetically favorable structures. While MD is very useful, it still has its limitations. Most notable, computing power and time are of constant concern.

Protein structure is inherently important due to the direct link between the structure of a protein and its function. One of the four levels of protein structure, the secondary structure, …

Preclinical Evaluation Of Ag10 For Therapeutic Use Against Familial Amyloid Cardiomyopathy And Its Application In Various Other Technologies, Mark Russell Miller

University of the Pacific Theses and Dissertations

Transthyretin (TTR) amyloidosis is a progressive, fatal disease in which deposition of amyloid derived from either mutant or wild-type TTR causes severe organ damage and dysfunction. TTR cardiomyopathy is an infiltrative, restrictive cardiomyopathy characterized by progressive left and right heart failure. Familial amyloid cardiomyopathy (FAC) is driven by pathogenic point mutations in the TTR gene that destabilize the TTR tetramer, prompting its dissociation into dimers and monomers, with subsequent misfolding, aggregation and deposition of toxic TTR amyloid aggregates in the myocardium. The most prevalent mutation that causes FAC is the V122I variant, carried by 3.4% of African Americans, that increases …

Detecting Agitation Onset In Individuals With Dementia Using Smart Phone Sensors, Christianne Fowler, Ajay Gupta, Kurt Maly, Karen Karlowicz, Maheedhar Gunnam, Rohila Gudipati, Mahesh Kukunooru, Rahul Rachamalla

Nursing Faculty Publications

Individuals living with dementia (ILWD) often experience problematic agitated behaviors, this occurs in up to 80% of ILWD. These behaviors lead to stress for caregivers and increased frequency of institutionalization. There are many proven methods to intervene during agitated behavior outburst and the earlier these methods are used the better the results. Technology has been used successfully to monitor many aspects of health monitoring for older adults. Technology is now being investigated to evaluate the effectiveness of predicting the onset of problem behaviors, especially escalating agitation in ILWD. Off the shelf technology, smart watches and android phones, are being tested …

Infusion Of Essentail Oils In Agarose Gels To Create Antimicrobial Surfaces, Simran Guron

Honors College Theses

The current use of antibiotics is very excessive in multiple settings, from treating patients to being present in cleaning products. This overuse of antibiotics is resulting in multiple consequences, ranging from having a negative impact on human health to breeding antibiotic-resistant strains of microorganisms. Antimicrobial surfaces are useful today to aid in sterilization, especially in the medical setting. This would help prevent the spread of infection of microorganisms in these settings. In our research, agarose acts as the antimicrobial surface and essential oils would act as the solution incorporated into the surface that has the antimicrobial properties. Agarose is a …

Advance Care Planning As A Shared Endeavor: Completion Of Acp Documents In A Multidisciplinary Cancer Program, Melissa A. Clark, Miles Q. Ott, Michelle L. Rogers, Mary C. Politi, Susan C. Miller, Laura Moynihan, Katina Robison, Ashley Stuckey, Don Dizon

Statistical and Data Sciences: Faculty Publications

Objective—We examined the roles of oncology providers in advance care planning (ACP) delivery in the context of a multidisciplinary cancer program.

Methods—Semi-structured interviews were conducted with 200 women with recurrent and/or metastatic breast or gynecologic cancer. Participants were asked to name providers they deemed important in their cancer care and whether they had discussed and/or completed ACP documentation. Evidence of ACP documentation was obtained from chart reviews.

Results—Fifty percent of participants self-reported completing an advance directive (AD) and 48.5% had named a healthcare power of attorney (HPA), 38.5% had completed both, and 39.0% had completed neither document. Among women who …

Intelligent Profiling Of Blood Donors In Ireland, Joanna Kossakowska

Theses

The demand for blood products in Ireland is constantly rising due to population growth and population ageing. It is believed that within the next decade these two factors will present challenges to blood donor recruitment and the availability of blood supplies. Improving the retention of blood donors will have a positive impact on the availability of blood products. Identification of suitable donors with the potential for long-term donating can potentially enhance the predictability of blood supply levels.

This research proposes that the patterns of blood donation behaviours of donors can be isolated from blood donor databases held by blood collecting …

Journal Of The Arkansas Academy Of Science- Volume 71 2017, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Impact Of Disease On The Survival Of Three Commercially Fished Species, John M. Hoenig, Maya L. Groner, Matthew W. Smith, Wolfgang K. Vogelbein, David M. Taylor, Donald F. Landers Jr., John T. Swenarton, David T. Gauthier

Biological Sciences Faculty Publications

Recent increases in emergent infectious diseases have raised concerns about the sustainability of some marine species. The complexity and expense of studying diseases in marine systems often dictate that conservation and management decisions are made without quantitative data on population-level impacts of disease. Mark-recapture is a powerful, underutilized, tool for calculating impacts of disease on population size and structure, even in the absence of etiological information. We applied logistic regression models to mark-recapture data to obtain estimates of disease-associated mortality rates in three commercially important marine species: snow crab (Chionoecetes opilio) in Newfoundland, Canada, that experience sporadic epizootics …

Research Strategies For Biomedical And Health Informatics: Some Thought-Provoking And Critical Proposals To Encourage Scientific Debate On The Nature Of Good Research In Medical Informatics, Reinhold Haux, Et Al.

Research Collection School Of Computing and Information Systems

Medical informatics, or biomedical and health informatics (BMHI), has become an established scientific discipline. In all such disciplines there is a certain inertia to persist in focusing on well-established research areas and to hold on to well-known research methodologies rather than adopting new ones, which may be more appropriate. To search for answers to the following questions: What are research fields in informatics, which are not being currently adequately addressed, and which methodological approaches might be insufficiently used? Do we know about reasons? What could be consequences of change for research and for education? Outstanding informatics scientists were invited to …

Linking Atr-Ftir And Raman Features To Phenolic Extractability And Other Attributes In Grape Skin, Hugh Byrne, Abigain Rooney, Julio Nogales-Bueno, Jose Miguel Hernandez-Hierro, Francisco Jose Heredia

Articles

The importance of wine phenolics on the sensory characteristic of red wines is well-known. Therefore, it is necessary to control the extractability of phenolic compounds from grape skins, which depends significantly on grape ripeness and hence, on cell wall degradation.

In the present study, attenuated total reflectance Fourier transform infrared (ATR-FTIR) and Raman spectra of grape skin have been recorded. Then, these spectral matrices have been studied and the main spectral features have been linked to extractabilities of phenolic compounds (anthocyanins, flavanols and total phenols). Moreover, spectral differences between external and internal grape skin surfaces also have been studied.

It …

Antimicrobial Activity Of Fractionated Borohydride-Capped And Electrochemical Colloidal Silver, Marjorie M. Markopoulos

Browse all Theses and Dissertations

Silver nanoparticles (AgNPs) and ionic silver (Ag+) are known to be broad-spectrum antimicrobial agents. Recent studies show these agents may be an alternative to the most widely used drinking water disinfectant, chlorine. Chlorine is a toxic industrial chemical with a lethal concentration of 430 ppm after 30 minutes. Additionally, chlorine can react with naturally occurring materials to produce a number of disinfection byproducts such as chloroform and trihalomethanes. Some of these byproducts pose cancer risks in addition to other negative impacts to human health. These would be eliminated with the use of Ag+ or AgNPs. The main goal of this …

Comparing Cmaq Forecasts With A Neural Network Forecast Model For Pm2.5 In New York, Samuel D. Lightstone, Fred Moshary, Barry Gross

Publications and Research

Human health is strongly affected by the concentration of fine particulate matter (PM2.5). The need to forecast unhealthy conditions has driven the development of Chemical Transport Models such as Community Multi-Scale Air Quality (CMAQ). These models attempt to simulate the complex dynamics of chemical transport by combined meteorology, emission inventories (EI’s), and gas/particle chemistry and dynamics. Ultimately, the goal is to establish useful forecasts that could provide vulnerable members of the population with warnings. In the simplest utilization, any forecast should focus on next day pollution levels, and should be provided by the end of the business day (5 p.m. …

Evaluation Of Levels Of Antibiotic Resistance In Groundwater-Derived E. Coli Isolates In The Midwest Of Ireland And Elucidation Of Potential Predictors Of Resistance, Jean O'Dwyer, Paul Hynds, Matthieu Pot, Catherine Adley, Michael Ryan

Articles

Antibiotic-resistant (pathogenic and non-pathogenic) organisms and genes are now acknowledged as significant emerging aquatic contaminants with potentially adverse human and ecological health impacts, and thus require monitoring. This study is the first to investigate levels of resistance among Irish groundwater (private wells) samples; Escherichia coli isolates were examined against a panel of commonly prescribed human and veterinary therapeutic antibiotics, followed by determination of the causative factors of resistance. Overall, 42 confirmed E. coli isolates were recovered from a groundwater-sampling cohort. Resistance to the human panel of antibiotics was moderate; nine (21.4%) E. coli isolates demonstrated resistance to one or more …

Geospatial Drivers Of The Groundwater Δ18o Isoscape In A Temperate Maritime Climate (Republic Of Ireland), S. Regan, R. Goodhue, O. Naughton, Paul Hynds

Articles

In recent years, the concept of “isoscapes” has been used to describe spatiotemporal stable isotope distributions within natural environments including groundwater systems at multiple scales. This study presents an updated groundwater δ18O isoscape for the Republic of Ireland and describes the climatic and geological drivers influencing 18O composition. In all, 142 geographically and geologically representative groundwater installations were sampled and analysed, in addition to 35 samples from six nested boreholes. Geospatially, Irish groundwater exhibits high δ18O values in southern and western coastal regions, becoming progressively depleted inland before reaching lowest measured values along the eastern coast, equating to a national …

Managing Operator Mental Workload With Standards Based Decision Support, Maurice Wilkins

H-Workload 2017: Models and Applications (Works in Progress)

H-Workload 2017: The first international symposium on human mental workload, Dublin Institute of Technology, Dublin, Ireland, June 28-30.

Moving Between Automated And Manual Driving: Mental Workload And Performance Implications, Totsapon Butmee, Terry C. Lansdown

H-Workload 2017: Models and Applications (Works in Progress)

Automated driving has been predicted to take-over from manual vehicle control in the near future. The driver’s role may then change from active operator to passive observer. Such technology offers the tantalising promise of improving driving safety. However, many studies have presented findings suggesting potentially adverse effects from automated driving systems, e.g., reduced situation awareness. Mental workload is also a key issue of concern for researchers in this area. Excessive mental workload has repeatedly been shown to be associated with degraded driving performance. Previously, most traffic psychology studies on mental workload have focused the manual driving task. However, a shift …

Distress And Worry As Mediators In The Relationship Between Psychosocial Risks And Upper Body Musculosketal Complaints In Highly Automated Manufacturing, Fiona Wixted, Leonard O'Sullivan

H-Workload 2017: Models and Applications (Works in Progress)

As a result of an upward trend in automation, the requirement for supervisory monitoring and consequently, cognitive demand has increased in automated manufacturing. The incidence of musculoskeletal disorders has also increased in the manufacturing sector. A model was developed based on survey data to test if distress and worry mediate the relationship between psychosocial factors (job control, cognitive demand, social isolation and skill discretion), stress states and upper body musculoskeletal complaints in highly automated manufacturing companies (n=235). Cognitive demand was shown to be related to higher distress in employees. The data raise the question about the link between job control …

Towards A Continuous Assessment Of Cognitive Workload For Smartphone Multitasking Users, Angel Jimenez-Molina, Hernan Lira

H-Workload 2017: Models and Applications (Works in Progress)

The intermeshing of Smartphone interactions and daily activities depletes the availability of cognitive resources. This excessive demand may lead to several undesirable cognitive states, which can be avoided by continuously assessing the user cognitive workload. Recently, many attempts have emerged to assess this workload by using psycho physiological signals. This paper provides evidence that it is possible to train models that accurately identify in short time windows such cognitive workload by processing heart rate and blood oxygen saturation signals. This assessment could be applied in Smartphone notification delivery, interface adaptations or cognitive capabilities evaluation.

Human Performance Modelling In Manufacturing: Mental Workload And Task Complexity, Maria Chiara Leva, Lorenzo Comberti, Micaela Demichela, Rebecca Duane

H-Workload 2017: Models and Applications (Works in Progress)

No abstract provided.

Facing Human Workload: The Resilient Ego: A Psychoanalytic Point Of View, Glauco Maria Genga, Maria Gabriella Pediconii

H-Workload 2017: Models and Applications (Works in Progress)

The paper aims to show new connections among Human Factors, Human Workload and Resilience. We intend: 1) to highlight the role of subject in facing the human workload, inflected as demanding tasks and emergency situations; 2) to show how psychoanalysis can provide novel insights, not only into human errors, but also into human resilience. They have a common denominator, at least in part: the role of subjective contributions even in demanding situations. Human workload includes a work for satisfaction. We recall also the case study of US Airways Flight 1549 water landing (the so called “Miracle on the Hudson”), which …

System Identification Of Motion Artifact: Noise In Eeg Headsets From Locomotion, Kaela Shea, James Tung

H-Workload 2017: Models and Applications (Works in Progress)

Fall prevention for geriatric populations is a growing concern among clinicians and researchers due to severe risk of morbidity and loss of independence. Emerging evidence has demonstrated that mental workload while walking influences gait stability and the risk for falling. Electroencephalography (EEG) presents a potential method to provide objective measures of mental workload, particularly during daily activities. Noise introduced to the EEG signal during motion, however, is restrictive. The study presented in the following paper isolates EEG signal noise attained from gait for a commercially accessible EEG system, the "Emotiv" Time and spectral system identification techniques were applied to model …

Online Measuring Of Available Resources, Enrique Munoz-De-Escalona, José Juan Canas

H-Workload 2017: Models and Applications (Works in Progress)

This paper present a proposal for measuring available mental resources during the accomplishment of a task. Our proposal consists in measuring emotions provoked by perceived self-efficacy in the execution of the task. Self-efficacy is one of the most important factors that affect the resources that a person puts at the disposal of the execution of the task. When a person perceives that he/she is not being effective he/she will activate more resources to improve his performance. This self-efficacy will be reflected in the emotions that the person experiences. A good efficacy will provoke positive emotions and a bad efficacy negative …

A Systems Approach To Predicting And Measuring Workload In Rail Traffic Management Systems, Joanna Evans

H-Workload 2017: Models and Applications (Works in Progress)

The introduction of systems such as Traffic Management (TM) will result in a number of changes in how the railway is managed for operations and maintenance staff such as, an increase in collaborative working styles and shared responsibilities. In order to react to these changing operational demands and user needs, TM workstation designs need to have greater flexibility and be configurable to support the information requirements for each specific role as well as support each role during different scenarios. Although this flexibility in system design has the potential to enhance performance, it increases the complexity of measuring operator workload. The …