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Articles 31 - 60 of 9056
Full-Text Articles in Medicine and Health Sciences
Modeling Interactions Between Platelet-Like Particles And Fibrin Matrix During Polymerization And Ultrasound Stimulation In Wound Healing Applications, Julia Sanger, Ashley C. Brown, Marie Muller, Mansoor A. Haider
Modeling Interactions Between Platelet-Like Particles And Fibrin Matrix During Polymerization And Ultrasound Stimulation In Wound Healing Applications, Julia Sanger, Ashley C. Brown, Marie Muller, Mansoor A. Haider
Biology and Medicine Through Mathematics Conference
No abstract provided.
Graphing The Curve: A Mathematical Expedition Into Social Distancing's Role In The South African Covid-19 Narrative, Chidozie Williams Chukwu
Graphing The Curve: A Mathematical Expedition Into Social Distancing's Role In The South African Covid-19 Narrative, Chidozie Williams Chukwu
Biology and Medicine Through Mathematics Conference
No abstract provided.
Stage Structured Model For Oyster Restoration With Larval Transport, Sarah Brownstein
Stage Structured Model For Oyster Restoration With Larval Transport, Sarah Brownstein
Biology and Medicine Through Mathematics Conference
No abstract provided.
Sperm-Egg Interaction For Fertilization Success, Prajakta P. Bedekar
Sperm-Egg Interaction For Fertilization Success, Prajakta P. Bedekar
Biology and Medicine Through Mathematics Conference
No abstract provided.
Modeling Synergistic Effects Of Integrin And Tgf-Beta Signaling In Epithelial Mesenchymal Transition, Prerak Thakkar
Modeling Synergistic Effects Of Integrin And Tgf-Beta Signaling In Epithelial Mesenchymal Transition, Prerak Thakkar
Biology and Medicine Through Mathematics Conference
No abstract provided.
A Random Differential Equation Model To Estimate Treatment Sensitivity In Synthetic And In Vitro Tumor Growth Data, Natalie Meacham
A Random Differential Equation Model To Estimate Treatment Sensitivity In Synthetic And In Vitro Tumor Growth Data, Natalie Meacham
Biology and Medicine Through Mathematics Conference
No abstract provided.
Understanding Cardiovascular Dynamics: Insights From Data Driven Nonlinear Hyperelastic Wall Modeling In Pulmonary Arteries, Md Arifuzzaman, Mette S. Olufsen, Mansoor A. Haider
Understanding Cardiovascular Dynamics: Insights From Data Driven Nonlinear Hyperelastic Wall Modeling In Pulmonary Arteries, Md Arifuzzaman, Mette S. Olufsen, Mansoor A. Haider
Biology and Medicine Through Mathematics Conference
No abstract provided.
Dual-Domain Clustering Of Spatiotemporal Infectious Disease Data, Samuel R. Thornton, Erin C.S. Acquesta, Patrick D. Finley, Mansoor A. Haider
Dual-Domain Clustering Of Spatiotemporal Infectious Disease Data, Samuel R. Thornton, Erin C.S. Acquesta, Patrick D. Finley, Mansoor A. Haider
Biology and Medicine Through Mathematics Conference
No abstract provided.
Incorporating Awareness, Misinformation And Optimal Control In A Model Of Sars-Cov-2, Eric Numfor
Incorporating Awareness, Misinformation And Optimal Control In A Model Of Sars-Cov-2, Eric Numfor
Biology and Medicine Through Mathematics Conference
No abstract provided.
Mathematical Modeling Of Immune Response To Sars-Cov-2, Hwayeon Ryu
Mathematical Modeling Of Immune Response To Sars-Cov-2, Hwayeon Ryu
Biology and Medicine Through Mathematics Conference
No abstract provided.
Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr
Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr
Biology and Medicine Through Mathematics Conference
No abstract provided.
Topological Data Analysis Of Molecular Dynamics Simulations Of Monoclonal Antibodies, Melinda Kleczynski, Christina Bergonzo, Anthony Kearsley
Topological Data Analysis Of Molecular Dynamics Simulations Of Monoclonal Antibodies, Melinda Kleczynski, Christina Bergonzo, Anthony Kearsley
Biology and Medicine Through Mathematics Conference
No abstract provided.
Stochastic Immunology Model And Its Analysis, Rahnuma Islam, David Swigon
Stochastic Immunology Model And Its Analysis, Rahnuma Islam, David Swigon
Biology and Medicine Through Mathematics Conference
No abstract provided.
A Stochastic Multi-Host Model For West Nile Virus: Determining The Probability Of Disease Extinction!, Suzanne Robertson
A Stochastic Multi-Host Model For West Nile Virus: Determining The Probability Of Disease Extinction!, Suzanne Robertson
Biology and Medicine Through Mathematics Conference
No abstract provided.
Clustering Using Self Organizing Maps In Biology, Olcay Akman
Clustering Using Self Organizing Maps In Biology, Olcay Akman
Biology and Medicine Through Mathematics Conference
No abstract provided.
Decoding Immune Cell Navigation: Integrating Artificial Life Modeling With Tumor Microenvironment Dynamics, Sadegh Marzban
Decoding Immune Cell Navigation: Integrating Artificial Life Modeling With Tumor Microenvironment Dynamics, Sadegh Marzban
Biology and Medicine Through Mathematics Conference
No abstract provided.
Plenary: Mathematics Of Malaria Transmission Dynamics: The Renewed Quest For Eradication, Abba Gumel
Plenary: Mathematics Of Malaria Transmission Dynamics: The Renewed Quest For Eradication, Abba Gumel
Biology and Medicine Through Mathematics Conference
No abstract provided.
Plenary: Insights Into Depression: Mathematical Approaches, Janet Best
Plenary: Insights Into Depression: Mathematical Approaches, Janet Best
Biology and Medicine Through Mathematics Conference
No abstract provided.
Spectral Characterization Of High-Speed Sers Fluctuations, Makayla Schmidt, Emily A. Farley, Marit A. Engevik, Alexandre G. Brolo, Nathan Lemke, Nathan Lindquist
Spectral Characterization Of High-Speed Sers Fluctuations, Makayla Schmidt, Emily A. Farley, Marit A. Engevik, Alexandre G. Brolo, Nathan Lemke, Nathan Lindquist
Science Symposium
The concept of plasmonic “hotspots” is central to the broad field of nanophotonics. In surface-enhanced Raman scattering (SERS), hotspots can increase Raman scattering efficiency by orders of magnitude. Hotspot dimensions may range from a few nanometers down to the atomic scale and are able to generate SERS signals from single molecules. However, these single-molecule SERS signals often show significant fluctuations, and the concept of intense, localized, yet static hotspots has come into question. Recent experiments have shown these SERS intensity fluctuations (SIFs) to occur over an extremely wide range of timescales, from seconds to micro-seconds, due to the various physical …
Heavy Metals In Afforested Mangrove Sediment From The World's Largest Delta: Distributional Mapping, Contamination Status, Risk Assessment And Source Tracing, Md Saifur Rahman, Moshiur Rahman, Yeasmin N Jolly, Md Kamal Hossain, Sanjida Afrin Semme, Bilal Ahamad Paray, Takaomi Arai, Jimmy Yu, M Belal Hossain
Heavy Metals In Afforested Mangrove Sediment From The World's Largest Delta: Distributional Mapping, Contamination Status, Risk Assessment And Source Tracing, Md Saifur Rahman, Moshiur Rahman, Yeasmin N Jolly, Md Kamal Hossain, Sanjida Afrin Semme, Bilal Ahamad Paray, Takaomi Arai, Jimmy Yu, M Belal Hossain
Journal Articles
This study aims to assess seasonal and spatial variations, contamination status, ecological risks, and metal sources (Ni, Pb, Cr, Cu, Mn, and Zn) in human-afforested mangrove sediments in a deltaic region. Five sampling locations were sampled during dry and wet seasons. Heavy metal concentrations followed the order: Mn > Zn > Ni > Cr > Cu > Pb. Metal loads, except Cu and Pb, were higher during the dry season, aligning with national and international recommendations. Sediment quality guidelines, contamination factor, geoaccumulation index, enrichment factors, and pollution load index indicated uncontaminated sediment in both seasons. Potential ecological risk assessment showed low risk conditions in all …
Identifying Phytoremediation Performing Plant Species That Can Be Utilized In The Improvement Of Heavy Metal Contaminated Soils, Ashley Clark*, Samuel Mutiti
Identifying Phytoremediation Performing Plant Species That Can Be Utilized In The Improvement Of Heavy Metal Contaminated Soils, Ashley Clark*, Samuel Mutiti
Graduate Research Showcase
Heavy metal pollution is a problem associated with industrialization and development. Two major metals that are commonly mined and can enter the environment, which can jeopardize communities’ health, are copper (Cu) and lead (Pb). There are different options for reducing heavy metal pollution in the environment via remediation efforts, including physical, chemical, and biological methods. However, physical and chemical remediation can be costly and labor-intensive, making them unsuitable for regions that do not have the funds to utilize these practices. Biological remediation is a more cost-conservative practice that has been shown in many studies to be effective in the gradual …
Code For Care: Hypertension Prediction In Women Aged 18-39 Years, Kruti Sheth
Code For Care: Hypertension Prediction In Women Aged 18-39 Years, Kruti Sheth
Electronic Theses, Projects, and Dissertations
The longstanding prevalence of hypertension, often undiagnosed, poses significant risks of severe chronic and cardiovascular complications if left untreated. This study investigated the causes and underlying risks of hypertension in females aged between 18-39 years. The research questions were: (Q1.) What factors affect the occurrence of hypertension in females aged 18-39 years? (Q2.) What machine learning algorithms are suited for effectively predicting hypertension? (Q3.) How can SHAP values be leveraged to analyze the factors from model outputs? The findings are: (Q1.) Performing Feature selection using binary classification Logistic regression algorithm reveals an array of 30 most influential factors at an …
Factors Predictive Of The Development Of Surgical Site Infection In Thyroidectomy, A Replication Study Of Myssiorek (2018), Kaitlyn M. Kenig
Factors Predictive Of The Development Of Surgical Site Infection In Thyroidectomy, A Replication Study Of Myssiorek (2018), Kaitlyn M. Kenig
Capstone Experience
The original study aimed to show that thyroidectomy does not result in surgical site infection (SSI) in most cases, and thus routine prescription of antibiotics is not necessary. The study looked to see what risk factors could predict the incidence of SSI. This would highlight those individuals who were at most risk of developing SSI, and then antibiotics would only be prescribed to these individuals instead of all or most individuals who undergo thyroidectomy.
This study used NSQIP data to look at incidence of SSI and look for risk factors that may be predictive of SSI. Only surgeries that were …
Evaluation Of An End-To-End Radiotherapy Treatment Planning Pipeline For Prostate Cancer, Mohammad Daniel El Basha, Court Laurence, Carlos Eduardo Cardenas, Julianne Pollard-Larkin, Steven Frank, David T. Fuentes, Falk Poenisch, Zhiqian H. Yu
Evaluation Of An End-To-End Radiotherapy Treatment Planning Pipeline For Prostate Cancer, Mohammad Daniel El Basha, Court Laurence, Carlos Eduardo Cardenas, Julianne Pollard-Larkin, Steven Frank, David T. Fuentes, Falk Poenisch, Zhiqian H. Yu
Dissertations & Theses (Open Access)
Radiation treatment planning is a crucial and time-intensive process in radiation therapy. This planning involves carefully designing a treatment regimen tailored to a patient’s specific condition, including the type, location, and size of the tumor with reference to surrounding healthy tissues. For prostate cancer, this tumor may be either local, locally advanced with extracapsular involvement, or extend into the pelvic lymph node chain. Automating essential parts of this process would allow for the rapid development of effective treatment plans and better plan optimization to enhance tumor control for better outcomes.
The first objective of this work, to automate the treatment …
Synthesis Of Thermoresponsive Poly(N-Isopropyl Acrylamide) Based Core-Shell And Hollow Shell Nanogel With Tunable Core And Shell Thickness, Mohamad Hijazi, Molla R. Islam
Synthesis Of Thermoresponsive Poly(N-Isopropyl Acrylamide) Based Core-Shell And Hollow Shell Nanogel With Tunable Core And Shell Thickness, Mohamad Hijazi, Molla R. Islam
Student Scholar Symposium Abstracts and Posters
Nanogels have emerged as a notably safer and more effective means for drug delivery, primarily due to their adjustable drug-loading capabilities. Hollow-core nanoparticles offer some unique properties that are desirable for drug delivery applications. Initially, silica core nanoparticles were synthesized using the Stöber process at different temperatures where Tetraethoxysilane (TEOS) undergoes hydrolysis in the presence of ethanol and then a condensation reaction to form silica nanoparticles. Scanning Electron Microscopy (SEM) and Optical Microscopy (OM) analysis revealed that the size of silica core particles varied with the synthesis temperature (300 nm at 30°C to 150 at 60°C). The core silica particles …
Mathematical Modeling And Examination Into Existing And Emerging Parkinson’S Disease Treatments: Levodopa And Ketamine, Gabrielle Riddlemoser
Mathematical Modeling And Examination Into Existing And Emerging Parkinson’S Disease Treatments: Levodopa And Ketamine, Gabrielle Riddlemoser
Undergraduate Honors Theses
Parkinson’s disease (PD) is the second most common neurodegenerative disease across the world, affecting over 6 million people worldwide. This disorder is characterized by the progressive loss of dopaminergic neurons within the substantia nigra pars compacta (SNpc) due to the aggregation of α-synuclein within the brain. Patients with PD develop motor symptoms such as tremors, bradykinesia, and postural instability, as well as a host of non-motor symptoms such as behavioral changes, sleep difficulties, and fatigue. The reduction of dopamine within the brain is the primary cause of these symptoms. The main form of treatment for PD is levodopa, a precursor …
Process Modeling The Neuroprotective Effects Of A Plant-Based Diet On Parkinson's Disease, Julia Mitchell
Process Modeling The Neuroprotective Effects Of A Plant-Based Diet On Parkinson's Disease, Julia Mitchell
Undergraduate Honors Theses
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms such as tremors, bradykinesia, rigidity, and postural instability. Recent research suggests an avenue for potential neuroprotection through dietary intervention, specifically the adoption of a plant-based diet. A plant-based diet predominantly comprises foods derived from plants, emphasizing fruits, vegetables, grains, legumes, and nuts while minimizing or excluding animal products. This thesis aims to explore the biochemical pathways implicated in PD progression and the potential impact of dietary choices on these pathways. The investigation focuses on several key pathways: alpha-synuclein aggregation, the blood-brain barrier crossing of levodopa, oxidative stress, ferroptosis, …
Synthesis Of Gold Nanoparticles Via Pulsed Liquid Ablation For Use In The Photodynamic Therapy Of Bacteria, Justice Ben Yosef
Synthesis Of Gold Nanoparticles Via Pulsed Liquid Ablation For Use In The Photodynamic Therapy Of Bacteria, Justice Ben Yosef
Masters Theses & Specialist Projects
With the ever-increasing threat of antibiotic resistant bacteria, alternative treatment methods have been developed including photodynamic therapy (PDT). Within the PDT process, photosensitizers are used to generate reactive oxygen species (ROS) and facilitate the cell termination process. This work lays the conceptual foundation for the functionalization of the photosensitizer methylene blue (MB) with gold nanoparticles (AuNPs) and INF-55 as a potential inhibitor of the AcrAB-TolC efflux pump to enhance the effectivity of the PDT process.
AuNPs were synthesized using pulsed laser ablation in an aqueous citrate solution. Both nanosecond and picosecond pulse durations, as well as both 532 nm and …
Grey Relational Analysis And Canonical Correlation Analysis Of Air Pollution In Three Kentucky Counties, Sarah Hartman
Grey Relational Analysis And Canonical Correlation Analysis Of Air Pollution In Three Kentucky Counties, Sarah Hartman
Masters Theses & Specialist Projects
Air pollution is a crucial factor that affects both the environment and public health. Various methods are available for assessing air quality and pollution levels, such as regression models, principal component analysis, and factor analysis tools. However, some of these methods present issues in multicollinearity and the nature of collected data. It is important to recognize that air pollution data is often uncertain, incomplete, and contains limited valid data points. Weather conditions and economic activities are also factors that can affect air pollution. With growing communities in Kentucky (KY), it is essential to address these factors as the state has …
Proof-Of-Concept For Converging Beam Small Animal Irradiator, Benjamin Insley
Proof-Of-Concept For Converging Beam Small Animal Irradiator, Benjamin Insley
Dissertations & Theses (Open Access)
The Monte Carlo particle simulator TOPAS, the multiphysics solver COMSOL., and
several analytical radiation transport methods were employed to perform an in-depth proof-ofconcept
for a high dose rate, high precision converging beam small animal irradiation platform.
In the first aim of this work, a novel carbon nanotube-based compact X-ray tube optimized for
high output and high directionality was designed and characterized. In the second aim, an
optimization algorithm was developed to customize a collimator geometry for this unique Xray
source to simultaneously maximize the irradiator’s intensity and precision. Then, a full
converging beam irradiator apparatus was fit with a multitude …