Medicine and Health Sciences Commons^™

Cost-Effectiveness Of Ivf Compared To Other Infertility Treatments; A United States Perspective, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Efficacy Of Greater Trochanteric Osteotomy Fixation, C. Clark, Van Nj, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Infertility Treatment: What Is A Cost-Effective Approach?, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Screening Women With Polycystic Ovarian Syndrome For Metabolic Syndrome, A. Dokras, M. Bochner, E. Hollinrake, S. Markham, Bradley Van Voorhis, D. Jagaisa

Bradley J Van Voorhis

No abstract provided.

Obesity And Insulin Resistance But Not Hyperandrogenism Mediates Vascular Dysfunction In Women With Polycystic Ovary Syndrome., Anuja Dokras, Dinesh Jagasia, Michelle Maifeld, Christine Sinkey, Bradley Van Voorhis, William Haynes

Bradley J Van Voorhis

OBJECTIVE: Polycystic ovary syndrome (PCOS) is associated with biochemical evidence of early atherosclerosis; however, data regarding vascular function are controversial. We hypothesized that resistance vessel function (mediated by the endothelium or smooth muscle) would be impaired in women with PCOS and aimed to determine the contribution of hyperandrogenism, obesity, or insulin resistance to vascular dysfunction.

DESIGN: Prospective study.

SETTING: University practice.

PATIENT(S): Women with PCOS (n = 24) and age/weight-matched controls (n = 22).

INTERVENTION(S): Vascular function was assessed by measuring forearm vasodilatation in response to both endothelium-dependent (acetylcholine/bradykinin) and endothelium-independent dilators (nitroprusside/verapamil).

MAIN OUTCOME MEASURE(S): Resistance vessel function.

RESULT(S): …

The Role Of Nitric Oxide In Female Reproduction, C. Weiner, L. Thompson, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Assisted Reproductive Technology: Counseling And Disclosure With Children, J. Gross, D. Clay, A. Stockman, Bradley Van Voorhis, Craig Syrop

Bradley J Van Voorhis

No abstract provided.

Obstetric Outcomes After In Vitro Fertilization In Obese And Morbidly Obese Women., Anuja Dokras, Lindsey Baredziak, Jill Blaine, Craig Syrop, Bradley Van Voorhis, Amy Sparks

Bradley J Van Voorhis

OBJECTIVE: In addition to numerous health detriments caused by obesity, fertility and pregnancy success may also be compromised. The aims of this study were to compare the effects of obesity and morbid obesity on in vitro fertilization (IVF) outcomes. We also investigated the effects of obesity on obstetric outcomes after IVF treatment. METHODS: Retrospective study of women less than 38 years of age during their first fresh IVF cycle (January 1995 to April 2005). RESULTS: A total of 1,293 women were included in the study, with 236 obese women (body mass index [BMI] = 30-39.9) and 79 morbidly obese women …

The Cost Of Infertility Evaluation And Therapy: Findings Of A Self-Insured University Healthcare Plan., D. Stovall, B. Allen, Amy Sparks, Craig Syrop, R. Saunders, Bradley Van Voorhis

Bradley J Van Voorhis

OBJECTIVE: To assess the total costs of infertility coverage, determine the proportion of healthcare costs related to infertility, compare infertility costs to those of other diseases, and calculate a per member per month cost of an infertility benefit. DESIGN: Historical prospective analysis. SETTING: A university-based, self-insured, fee-for-service healthcare plan. PATIENT(S): Healthcare policy members from January 1993 through December 1995. INTERVENTION(S): General and infertility-specific healthcare that included diagnostic tests for infertility, induction of ovulation, artificial insemination, donor gametes, in vitro fertilization, gamete intrafallopian transfer, zygote intrafallopian transfer, microsurgical epididymal sperm aspiration, embryo cryopreservation, and frozen embryo transfer. MAIN OUTCOME MEASURE(S): Healthcare …

Microrna Expression In The Human Blastocyst, E. Rosenbluth, D. Shelton, Amy Sparks, Eric Devor, L. Christenson, Bradley Van Voorhis

Bradley J Van Voorhis

OBJECTIVE: To determine the most highly expressed microRNAs (miRNAs) in human blastocysts and to compare miRNAs in euploid versus aneuploid embryos and in male versus female embryos. DESIGN: Experimental study of human embryos: 14 blastocysts (four male, five female, and five aneuploid) were evaluated for miRNA expression with the use of an array-based quantitative real-time polymerase chain reaction (qPCR). Highly expressed and differentially expressed miRNAs were confirmed with the use of qPCR in an expanded set of 27 blastocysts (seven male, eleven female, and nine aneuploid). SETTING: Academic IVF program. PATIENT(S): Thirteen couples donated 91 cryopreserved embryos for this study. …

Embryo Transfer In Ivf: Evidence-Based Clinical Practice, Lindsay Mains, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Decision To Do Iui Or Ivf - Sperm Count? Reply, Bradley Van Voorhis, Amy Sparks, Craig Syrop

Bradley J Van Voorhis

No abstract provided.

Role, Epidemiology, And Natural History Of Benign Uterine Mass Lesions., Ginny Ryan, Craig Syrop, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Reducing The Risk Of Multi-Fetal Gestation By Implementation Of A Single Blastocyst Transfer Policy., Amy Sparks, G. Ryan, C. Sipe, A. Dokras, Craig Syrop, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Endothelial Function Is Significantly Impaired Only In Obese Women With Polycystic Ovary Syndrome., A. Dokras, D. Jagasia, M. Maifeld, C. Sinkey, Bradley Van Voorhis, W. Haynes

Bradley J Van Voorhis

No abstract provided.

Ultrasound Is The Optimal Choice For Guidance In Difficult Hysteroscopy., J. Kresowik, Craig Syrop, Bradley Van Voorhis, Ginny Ryan

Bradley J Van Voorhis

OBJECTIVES: To compare costs and complications associated with ultrasound-guided hysteroscopy vs laparoscopy-guided hysteroscopy vs hysteroscopy alone for the surgical repair of intrauterine septa and synechiae. METHODS: This was a retrospective cohort study. Charts of all patients undergoing reparative surgery for intrauterine synechiae or uterine septa at our academic institution between 2000 and 2008 were reviewed. A total of 159 procedures were included in the study, categorized into concurrent laparoscopic guidance (n = 69), ultrasound guidance (n = 52) or no guidance (n = 38). Data regarding billing, surgical case logs and complications were collected for these procedures. Using these data, …

The Effectiveness Of Sublingual Progesterone Administration During Cryopreserved Embryo Transfer Cycles: Results Of A Matched Follow-Up Study, D. Stovall, Amy Sparks, Bradley Van Voorhis, F. Chapler, K. Mattingly, Craig Syrop

Bradley J Van Voorhis

No abstract provided.

Anovulation May Be A Risk Factor For Major Birth Defects In Children Born After Infertility Treatment., Bradley Van Voorhis, Amy Sparks, Craig Syrop, C. Sipe, G. Ryan, A. Dokras

Bradley J Van Voorhis

No abstract provided.

A Mandatory Single Blastocyst Transfer Policy With Educational Campaign In A United States Ivf Program Reduces Multiple Gestation Rates Without Sacrificing Pregnancy Rates, Ginny Ryan, Amy Sparks, C. Sipe, Craig Syrop, A. Dokras, Bradley Van Voorhis

Bradley J Van Voorhis

OBJECTIVE: To reduce the twin rate in our IVF program. DESIGN: A prospective educational study of infertile couples; a retrospective review of IVF outcomes before vs. after mandatory single embryo transfer (mSBT) policy change. SETTING: University-based infertility center. PATIENT(S): One hundred ten of 120 consecutive new infertile couples completed the educational study. Outcomes of all embryo transfers (n = 693) performed 17 months before and 17 months after mSBT were evaluated. INTERVENTION(S): A 1-page educational summary of comparative risks of twins vs. singletons to maternal and child health. MAIN OUTCOME MEASURE(S): Knowledge of twin risks and desired number of embryos …

Identification Of Apolipoprotein A1 In The Human Embryonic Secretome, Lindsay Mains, Lane Christenson, Baoli Yang, Amy Sparks, Satya Mathur, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

The Relationship Of Bleeding Patterns To Daily Reproductive Hormones In Women Approaching Menopause, Bradley Van Voorhis, Nanette Santoro, Sioban Harlow, Sybil Crawford, John Randolph

Bradley J Van Voorhis

No abstract provided.

Early Diagnosis Of Ovarian Torsion By Color Doppler Ultrasonography, Bradley Van Voorhis, J. Schwaiger, Craig Syrop, F. Chapler

Bradley J Van Voorhis

Ovarian torsion is often difficult to diagnose because of the nonspecific nature of the clinical findings. We report on the use of color Doppler ultrasonography in diagnosing early ovarian torsion. This technique provides a highly specific finding, the absence of blood flow to the ovary, that greatly facilitates the diagnosis of ovarian torsion.

Predictive Value Of Strict Criteria Sperm Morphology For Intrauterine Insemination Outcomes., Amy Sparks, Bradley Van Voorhis, L. Holz, A. Dokras, W. Davis, Craig Syrop

Bradley J Van Voorhis

No abstract provided.

Evolving Role Of Assisted Reproductive Technologies, Evan Rosenbluth, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

A Majority Of Women Delay Childbearing In Both Fertile And Infertile Groups Despite Understanding The Risks Of Aging On Fertility, Ginny Ryan, Rachel Maassen, A. Dokras, Craig Syrop, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Ethical Obligation For Restricting The Number Of Embryos Transferred To Women: Combating The Multiple-Birth Epidemic From In Vitro Fertilization, Bradley Van Voorhis, Ginny Ryan

Bradley J Van Voorhis

In vitro fertilization (IVF) is an increasingly effective and popular means of achieving pregnancy for infertile women, but contributes to a growing incidence of risky twin pregnancies. Despite studies demonstrating cost-effective means to achieve IVF pregnancy while strictly limiting the number of embryos transferred, multiple-embryo transfer remains the most common practice in the United States, and twin pregnancies continue to increase. IVF providers resist restricting these practices, arguing that this is counter to principles of procreative liberty, patient and professional autonomy, and free-market economics. We counter that physicians have a professional fiduciary responsibility to weigh issues of nonmaleficence to patients …

Messenger Ribonucleic Acid For The Gonadal Luteinizing Hormone Human Chorionic Gonadotropin Receptor Is Not Present In Human Endometrium, E. Stewart, M. Sahakian, A. Rhoades, Bradley Van Voorhis, R. Nowak

Bradley J Van Voorhis

No abstract provided.

Assisted Reproduction And Risk Of Birth Defects., C. Olson, Craig Syrop, A. Dokras, Amy Sparks, W. Davis, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Sonohysterography In Premenopausal Women With And Without Abnormal Bleeding, M. Clevenger-Hoeft, Craig Syrop, D. Stovall, Bradley Van Voorhis

Bradley J Van Voorhis

No abstract provided.

Performance Of The Postwash Total Motile Sperm Count As A Predictor Of Pregnancy At The Time Of Intrauterine Insemination: A Meta-Analysis, J. Van Weert, S. Repping, Bradley Van Voorhis, F. Van Der Veen, P. Bossuyt, B. Mol

Bradley J Van Voorhis

No abstract provided.