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Ambulatory Surgery. The Selection And Administration Of Perioperative Intravenous Fluids For The Pediatric Patient, J. Aker, Cormac O'Sullivan Sep 2012

Ambulatory Surgery. The Selection And Administration Of Perioperative Intravenous Fluids For The Pediatric Patient, J. Aker, Cormac O'Sullivan

Cormac T. O'Sullivan

No abstract provided.


Nurse Absenteeism And Workload: Negative Effect On Restraint,, L Unruh, Maria Joseph, M Strickland Sep 2012

Nurse Absenteeism And Workload: Negative Effect On Restraint,, L Unruh, Maria Joseph, M Strickland

Maria (Lindell) Joseph

No abstract provided.


Innovativeness In Nursing: A Phenomenological And Constructivist Study, Maria Joseph Sep 2012

Innovativeness In Nursing: A Phenomenological And Constructivist Study, Maria Joseph

Maria (Lindell) Joseph

Hospital administration and the medical field have maintained the status quo of nursing practice, in which nurses have adopted bureaucratic structures where conformity and regimentation are maintained to ensure large-scale efficiency. The lack of control to act on nursing knowledge and expert judgment is linked to work conditions of oppression, lack of autonomy, dissatisfaction, concomitant patient mortality, and morbidity. A climate of innovativeness is one strategy to reverse the negative impact caused by hospital administration and the medical field. The purpose of this phenomenological study was to explore the behavioral characteristics of lived experiences and knowledge of innovativeness among nurses …


An Examination Of The Sustainable Adoption Of Whole-Person Care (Wpc), Maria Joseph, D. Laughon, Richard Bogue Sep 2012

An Examination Of The Sustainable Adoption Of Whole-Person Care (Wpc), Maria Joseph, D. Laughon, Richard Bogue

Maria (Lindell) Joseph

AIM: This study illustrates how King's theory of goal attainment was used to focus an examination of whole-person care (WPC) and to extend the range of knowledge needed for WPC and nursing practice. BACKGROUND: Leadership implemented a faith-based innovation using continuing education for patient care that incorporates body-mind-spirit and eight principles called CREATION. Three questions arose: (1) Is there an evidence-based framework to determine whether the philosophy supports the discipline of nursing? (2) How extensive is the adoption and application of WPC? (3) Does the model make a difference in the context of nurse-patient interactions and outcomes in support of …


Engaging Learners: Challenges, Strategies, And Classroom Assessment, Sarah Beckman, S Boxley-Harges Sep 2012

Engaging Learners: Challenges, Strategies, And Classroom Assessment, Sarah Beckman, S Boxley-Harges

Sarah J. Beckman

Challenges of engaging students on real world culturally sensitive topics in a general education transcultural course are the essence of this presentation. Strategies used to create a safe environment in which students are free to state beliefs and opinions also hold students accountable to listen and respect other viewpoints. To this end, utilization of ground rules on civility, evidence-based teaching principles, and classroom assessment findings will be explored in relation to selection of teaching methods.


Simulation-Based Interprofessional Learning: The Way Forward, Janet Willhaus Sep 2012

Simulation-Based Interprofessional Learning: The Way Forward, Janet Willhaus

Janet Willhaus

This presentation will focus on the nurse educator perspectives and rich exemplars shared at the Nursing IPE Think Tank from the 2011 NLN Education Summit. Topics for discussion will include known documents supporting IPE, barriers and opportunities, exemplars of collaboration with other disciplines, and nursing priorities for future IPE progress.


Platelet-Derived Growth Factor Receptor-Alpha-Expressing Cells Localize To The Alveolar Entry Ring And Have Characteristics Of Myofibroblasts During Pulmonary Alveolar Septal Formation, Stephen E. Mcgowan, Ruth E. Grossmann, Patricia Kimani, Amey J. Holmes Sep 2012

Platelet-Derived Growth Factor Receptor-Alpha-Expressing Cells Localize To The Alveolar Entry Ring And Have Characteristics Of Myofibroblasts During Pulmonary Alveolar Septal Formation, Stephen E. Mcgowan, Ruth E. Grossmann, Patricia Kimani, Amey J. Holmes

Ruth E. Grossmann

Platelet-derived growth factor-A and its receptor, platelet-derived growth factor receptor-alpha (PDGF-Rα), are required for formation of the secondary pulmonary alveolar septa in mice. However, it remains unclear how these molecules direct the secondary septation process. We have examined the abundance, location, and the accumulation of alpha-smooth muscle actin (αSMA), neutral lipid droplets, and elastin in the proximity of PDGF-Rα-expressing alveolar cells during postnatal days 4 through 12 in the mouse. PDGF-Rα-expressing cells preferentially have characteristics of myofibroblasts and were more likely to contain αSMA than are alveolar cells that do not express PDGF-Rα. PDGF-Rα expressing cells were preferentially located in …


Pilot Study Of Vitamin D Supplementation In Adults With Cystic Fibrosis Pulmonary Exacerbation, Ruth Grossmann, Susu Zughaier, Meena Kumari, Shabnam Seydafkan, Robert Lyles, Shuling Liu, Viranuj Sueblinvong, Michael Schechter, Arlene Stecenko, Thomas Ziegler, Vin Tangpricha Sep 2012

Pilot Study Of Vitamin D Supplementation In Adults With Cystic Fibrosis Pulmonary Exacerbation, Ruth Grossmann, Susu Zughaier, Meena Kumari, Shabnam Seydafkan, Robert Lyles, Shuling Liu, Viranuj Sueblinvong, Michael Schechter, Arlene Stecenko, Thomas Ziegler, Vin Tangpricha

Ruth E. Grossmann

Background: Vitamin D insufficiency is common in cystic fibrosis (CF) and vitamin D repletion may have an important role in improving clinical outcomes in CF. This randomized, placebo-controlled, pilot study examined the feasibility and impact of a single, large dose of cholecalciferol on vitamin D status and clinical outcomes in subjects with CF. Methods: Thirty adults with were randomized in a double-blinded, pilot study to receive 250,000 IU cholecalciferol or placebo within 48 h of hospital admission for a pulmonary exacerbation. Concentrations of 25-hydroxyvitamin D (25(OH)D), clinical outcomes and potential adverse events were assessed up to one year after randomization. …


Impact Of Vitamin D Supplementation On Markers Of Inflammation In Adults With Cystic Fibrosis Hospitalized For A Pulmonary Exacerbation, Ruth Grossmann, S. Zughaier, S. Liu, R. Lyles, V. Tangpricha Sep 2012

Impact Of Vitamin D Supplementation On Markers Of Inflammation In Adults With Cystic Fibrosis Hospitalized For A Pulmonary Exacerbation, Ruth Grossmann, S. Zughaier, S. Liu, R. Lyles, V. Tangpricha

Ruth E. Grossmann

Patients with cystic fibrosis (CF) suffer from chronic lung infection and inflammation leading to respiratory failure. Vitamin D deficiency is common in patients with CF, and correction of vitamin D deficiency may improve innate immunity and reduce inflammation in patients with CF. We conducted a double-blinded, placebo-controlled, randomized clinical trial of high-dose vitamin D to assess the impact of vitamin D therapy on antimicrobial peptide concentrations and markers of inflammation. We randomized 30 adults with CF hospitalized with a pulmonary exacerbation to 250 000 IU of cholecalciferol or placebo, and evaluated changes in plasma concentrations of inflammatory markers and the …


Risk Factors For Vitamin D Deficiency And Relationship With Cardiac Biomarkers, Inflammation And Immune Restoration In Hiv-Infected Youth, A. Eckard, S. Judd, T. Ziegler, A. Camacho-Gonzalez, A. Fitzpatrick, G. Hadley, Ruth Grossmann, L. Seaton, S. Seydafkan, M. Mulligan, N. Rimann, V. Tangpricha, G. Mccomsey Sep 2012

Risk Factors For Vitamin D Deficiency And Relationship With Cardiac Biomarkers, Inflammation And Immune Restoration In Hiv-Infected Youth, A. Eckard, S. Judd, T. Ziegler, A. Camacho-Gonzalez, A. Fitzpatrick, G. Hadley, Ruth Grossmann, L. Seaton, S. Seydafkan, M. Mulligan, N. Rimann, V. Tangpricha, G. Mccomsey

Ruth E. Grossmann

BACKGROUND: Vitamin D deficiency is common in HIV-infected individuals. In adults, traditional and HIV-related factors play a role in vitamin D status, and deficiency appears to impair immune restoration and exacerbate HIV complications, like cardiovascular disease (CVD). This study sought to determine factors contributing to vitamin D status in HIV-infected youth and investigate the relationship with CVD risk, inflammation and immune restoration. METHODS: HIV-infected subjects (1-25 years old) were enrolled prospectively along with healthy controls that were group-matched by age, sex and race. HIV data were collected for the HIV-infected group, while traditional risk factors, including vitamin D intake, sun …


Vitamin D And Chronic Lung Disease: A Review Of Molecular Mechanisms And Clinical Studies, J. Finklea, Ruth Grossmann, V. Tangpricha Sep 2012

Vitamin D And Chronic Lung Disease: A Review Of Molecular Mechanisms And Clinical Studies, J. Finklea, Ruth Grossmann, V. Tangpricha

Ruth E. Grossmann

Vitamin D is classically recognized for its role in calcium homeostasis and skeletal metabolism. Over the last few decades, vitamin D deficiency has increased in prevalence in adults and children. Potential extraskeletal effects of vitamin D have been under investigation for several diseases. Several cross-sectional studies have associated lower vitamin D status with decreased lung function. This finding has prompted investigators to examine the association of vitamin D deficiency with several chronic lung diseases. One major focus has been the link between maternal vitamin D status and childhood asthma. Vitamin D deficiency has also been associated with increased risk of …


Pdgf-Ralpha Gene Expression Predicts Proliferation, But Pdgf-A Suppresses Transdifferentiation Of Neonatal Mouse Lung Myofibroblasts, P. Kimani, A. Holmes, Ruth Grossmann, S. Mcgowan Sep 2012

Pdgf-Ralpha Gene Expression Predicts Proliferation, But Pdgf-A Suppresses Transdifferentiation Of Neonatal Mouse Lung Myofibroblasts, P. Kimani, A. Holmes, Ruth Grossmann, S. Mcgowan

Ruth E. Grossmann

BACKGROUND: Platelet-derived growth factor A (PDGF-A) signals solely through PDGF-Ralpha, and is required for fibroblast proliferation and transdifferentiation (fibroblast to myofibroblast conversion) during alveolar development, because pdgfa-null mice lack both myofibroblasts and alveoli. However, these PDGF-A-mediated mechanisms remain incompletely defined. At postnatal days 4 and 12 (P4 and P12), using mouse lung fibroblasts, we examined (a) how PDGF-Ralpha correlates with ki67 (proliferation marker) or alpha-smooth muscle actin (alphaSMA, myofibroblast marker) expression, and (b) whether PDGF-A directly affects alphaSMA or modifies stimulation by transforming growth factor beta (TGFbeta). METHODS: Using flow cytometry we examined PDGF-Ralpha, alphaSMA and Ki67 in mice which …


Evaluation Of Vehicle Substances On Vitamin D Bioavailability: A Systematic Review, Ruth Grossmann, V. Tangpricha Sep 2012

Evaluation Of Vehicle Substances On Vitamin D Bioavailability: A Systematic Review, Ruth Grossmann, V. Tangpricha

Ruth E. Grossmann

Vitamin D insufficiency is a common medical condition. Vitamin supplements can be ingested to improve vitamin D status. It is not known if the vehicle substance that is combined with the vitamin D tablet influences the bioavailability of vitamin D. The purpose of this review is to examine the impact of different vehicles on vitamin D bioavailability. A comprehensive literature search identified studies that directly compared the absorption of vitamin D from two or more vehicles. The change in mean serum 25(OH)D per average daily dose of vitamin D supplemented was calculated and compared among the studies. We identified four …


Literacy-Appropriate Educational Materials And Brief Counseling Improve Diabetes Self-Management, Andrea Wallace, H. Seligman, T. Davis, D. Schillinger, C. Arnold, B. Bryant-Shilliday, J. Freburger, D. Dewalt Sep 2012

Literacy-Appropriate Educational Materials And Brief Counseling Improve Diabetes Self-Management, Andrea Wallace, H. Seligman, T. Davis, D. Schillinger, C. Arnold, B. Bryant-Shilliday, J. Freburger, D. Dewalt

Andrea S. Wallace

OBJECTIVE: In this pilot study, we evaluated the impact of providing patients with a literacy-appropriate diabetes education guide accompanied by brief counseling designed for use in primary care. METHODS: We provided the Living with Diabetes guide and brief behavior change counseling to 250 English and Spanish speaking patients with type 2 diabetes. Counseling sessions using collaborative goal setting occurred at baseline and by telephone at 2 and 4 weeks. We measured patients' activation, self-efficacy, diabetes distress, knowledge, and self-care at baseline and 3-month follow-up. RESULTS: Statistically significant (p


Low Health Literacy: Overview, Assessment, And Steps Toward Providing High-Quality Diabetes Care, Andrea Wallace Sep 2012

Low Health Literacy: Overview, Assessment, And Steps Toward Providing High-Quality Diabetes Care, Andrea Wallace

Andrea S. Wallace

Approximately half of all Americans do not understand written and verbal health information well enough to take appropriate action. For chronic conditions requiring patients' ongoing self-management, limited literacy may be a powerful barrier to achieving optimal outcomes. Because low literacy is associated with a number of psychosocial variables that also act as barriers to self-management, health literacy experts recommend that efforts to alleviate the burden introduced by low literacy be addressed not only by developing means of increasing patients' understanding, but also by integrating such efforts into systems aiming to improve self-management support across the continuum of patient care. This …


Race, Care Seeking, And Utilization For Chronic Back And Neck Pain: Population Perspectives, T. Carey, J. Freburger, G. Holmes, A. Jackman, S. Knauer, Andrea Wallace, J. Darter Sep 2012

Race, Care Seeking, And Utilization For Chronic Back And Neck Pain: Population Perspectives, T. Carey, J. Freburger, G. Holmes, A. Jackman, S. Knauer, Andrea Wallace, J. Darter

Andrea S. Wallace

We analyzed a statewide survey of individuals with chronic back and neck pain to determine whether prevalence and care use varied by patient race or ethnicity. We conducted a telephone survey of a random sample of 5,357 North Carolina households in 2006. Adults with chronic (>3 months duration or >24 episodes of pain per year), impairing back or neck pain were identified and were asked to complete a survey about their health and care utilization. 837 respondents (620 white, 183 black, 34 Latino) reported chronic back or neck pain. Whites and blacks had similar rates of chronic back pain. …


Accessing Asthma Care: A Case Study Of Urban Children, Andrea Wallace Sep 2012

Accessing Asthma Care: A Case Study Of Urban Children, Andrea Wallace

Andrea S. Wallace

The purpose of this exploratory, descriptive study was to identify factors that facilitate or impede the use of health care resources by urban children with asthma. Using an embedded case study design, the study considered the issue of health care access for urban children with asthma by focusing on attributes that impede and facilitate these children's access to health care resources. Interview, demographic, survey, and medical records data were analyzed for 34 parent-child dyads accessing asthma care in one metropolitan health care system. Interview data from 14 health care professionals were also analyzed. These findings were then compared with utilization …


Work Environment Characteristics Of High-Quality Home Health Agencies, S. Tullai-Mcguinness, J. Riggs, Amany Farag Sep 2012

Work Environment Characteristics Of High-Quality Home Health Agencies, S. Tullai-Mcguinness, J. Riggs, Amany Farag

Amany A. Farag

This concurrent mixed-method study examines the nurse work environment of high-quality Medicare-certified home health agencies. High-quality (n=6) and low-quality (n=6) home health agencies were recruited using agency-level publicly reported patient outcomes. Direct care registered nurses (RNs) from each agency participated in a focus group and completed the Practice Environment Scale of the Nurse Work Index (PES-NWI). No significant differences were found in the PES-NWI results between nurses working in high- and low-quality agencies, though nurses in high-quality agencies scored higher on all subscales. Nurses working in all the high-quality agencies identified themes of adequate staffing, supportive managers, and team work. …


Expanded Adult Day Program As A Transition Option From Hospital To Home, K. Jones, S. Tullai-Mcguinness, M. Dolansky, Amany Farag, M. Krivanek, L. Matthews Sep 2012

Expanded Adult Day Program As A Transition Option From Hospital To Home, K. Jones, S. Tullai-Mcguinness, M. Dolansky, Amany Farag, M. Krivanek, L. Matthews

Amany A. Farag

This article describes a pilot program for provision of postacute care (PAC) in an established adult day program. Demographic, clinical, utilization, and satisfaction data were abstracted retrospectively from program records; postdischarge readmission and emergency department visit data were obtained from the electronic health record. Comparative data were obtained from the health records of patients who were offered but declined the adult day program. Between 2005 and 2008, 78 patients requiring PAC were approached by the RN coordinator; 33 selected the adult day program, and 45 selected alternative destinations. The majority of patients had a neurological diagnosis, most commonly stroke. Participants …


Nurses' Perception Of Their Manager's Leadership Style And Unit Climate: Are There Generational Differences?, Amany Farag, S. Tullai-Mcguinness, M. Anthony Sep 2012

Nurses' Perception Of Their Manager's Leadership Style And Unit Climate: Are There Generational Differences?, Amany Farag, S. Tullai-Mcguinness, M. Anthony

Amany A. Farag

AIM: To describe and compare how nurses representing four age cohorts perceive their manager's leadership style and unit climate. BACKGROUND: The current workforce consists of nurses representing four generational cohorts. Nursing literature suggests that nurses from each age cohort think, behave and approach work differently. Limited empirical evidence, however, exists about how nurses from each age cohort perceive two aspects of their work environment: their managers' leadership style and unit climate. METHOD: This cross-sectional, descriptive survey was conducted using a convenience sample of 475 registered nurses working in different inpatient units in three community non-magnet hospitals. RESULTS AND CONCLUSION: Only …


Multigenerational Nursing Workforce Value Differences And Work Environment: Impact On Rns' Turnover Intentions, Amany Farag Sep 2012

Multigenerational Nursing Workforce Value Differences And Work Environment: Impact On Rns' Turnover Intentions, Amany Farag

Amany A. Farag

Despite ongoing nursing retention efforts, the national turnover rate continues to climb as high as 21% annually. Creating a climate that supports retention is among the many responsibilities of first line nurse manager. This task is challenged by the presence of multigenerational nursing workforce. Nurses from different age cohorts come to the work environment with different set of professional and generational (terminal and instrumental) values. Values are enduring beliefs about what constitutes desirable and acceptable behavior; values play a fundamental role in both decision making and meaning formation processes. Nursing literature suggested that nurses from different age cohorts may perceive …


Relationships Among Stress Measures, Risk Factors And Inflammatory Biomarkers In Law Enforcement Officers, Sandra Ramey, Nancy Downing, W. Franke, Elena Perkhounkova, M. Alasagheirin Sep 2012

Relationships Among Stress Measures, Risk Factors And Inflammatory Biomarkers In Law Enforcement Officers, Sandra Ramey, Nancy Downing, W. Franke, Elena Perkhounkova, M. Alasagheirin

Nancy R Downing

Law enforcement officers suffer higher morbidity and mortality rates from all causes than the general population. Cardiovascular disease (CVD) accounts for a significant portion of the excess illness, with a reported prevalence as high as 1.7 times that of the general population. To determine which occupational hazards cause this increased risk and morbidity, it is imperative to study law enforcement officers before they retire. The long-range goal of our research is to reduce the incidence of CVD-related illness and death among aging law enforcement officers. The purpose of the present study was to measure pro- and anti-atherogenic inflammatory markers in …


Self Reports Of Day-To-Day Function In A Small Cohort Of People With Prodromal And Early Hd, Janet Williams, Nancy Downing, A. Vaccarino, M. Guttman, J. Paulsen Sep 2012

Self Reports Of Day-To-Day Function In A Small Cohort Of People With Prodromal And Early Hd, Janet Williams, Nancy Downing, A. Vaccarino, M. Guttman, J. Paulsen

Nancy R Downing

Day-to-day functioning is a component of health-related quality of life and is an important end point for therapies to treat Huntington Disease (HD). Specific areas of day-to-day function changes have not been reported for prodromal or very early stages of HD. An exploratory self-report telephone interview was conducted with sixteen people with prodromal HD or early HD who met criteria designed to capture research participants most near to motor diagnosis. All completed semi-structured interviews on function in nine aspects of day-to-day life. Out of 16, 14 reported changes in at least one area. All day-to-day function areas were endorsed by …


Researcher And Institutional Review Board Chair Perspectives On Incidental Findings In Genomic Research, Janet K. Williams, Sandra Daack-Hirsch, Martha Driessnack, Nancy R. Downing, L. Shinkunas, D. Brandt, C. Simon Sep 2012

Researcher And Institutional Review Board Chair Perspectives On Incidental Findings In Genomic Research, Janet K. Williams, Sandra Daack-Hirsch, Martha Driessnack, Nancy R. Downing, L. Shinkunas, D. Brandt, C. Simon

Nancy R Downing

Aims: Genomic research can produce findings unrelated to a study's aims. The purpose of this study was to examine researcher and Institutional Review Board (IRB) chair perspectives on genomic incidental findings (GIFs). Methods: Nineteen genomic researchers and 34 IRB chairs from 42 institutions participated in semi-structured telephone interviews. Researchers and chairs described GIFs within their respective roles. Few had direct experience with disclosure of GIFs. Researchers favored policies where a case by case determination regarding whether GIF disclosure would be offered after discovery, whereas IRB chairs preferred policies where procedures for disclosure would be determined prior to approval of the …


Perceived Stress In Prodromal Huntington Disease, Nancy Downing, M. Smith, L. Beglinger, J. Mills, K. Duff, K. Rowe, E. Epping, J. Paulsen, Group Predict-Hd Investigators Of Huntington Study Sep 2012

Perceived Stress In Prodromal Huntington Disease, Nancy Downing, M. Smith, L. Beglinger, J. Mills, K. Duff, K. Rowe, E. Epping, J. Paulsen, Group Predict-Hd Investigators Of Huntington Study

Nancy R Downing

This study examines perceived stress and its relationship to depressive symptoms, life changes and functional capacity in a large sample of individuals who are positive for the Huntington disease (HD) gene expansion but not yet diagnosed. Participants were classified by estimated proximity to HD diagnosis (far, mid, near) and compared with a non-gene-expanded comparison group. Persons in the mid group had the highest stress scores. A significant interaction between age and time since HD genetic testing was also found. Secondary analyses using data from a different data collection point and including a diagnosed group showed the highest stress scores in …


The Perception Of Role Conflict In Sexual Assault Nursing And Its Effects On Care Delivery, Nancy Downing, Melissa Lehan Macklin Sep 2012

The Perception Of Role Conflict In Sexual Assault Nursing And Its Effects On Care Delivery, Nancy Downing, Melissa Lehan Macklin

Nancy R Downing

The role of the sexual assault nurse examiner (SANE) combines two once-distinct roles--nursing and forensic science. Therefore, there is a potential for role conflict that may impact SANEs as well as the care they deliver. In this qualitative study, 14 SANEs were interviewed regarding their roles. Most participants did not endorse role conflict; however, most also provided examples of conflict between their roles as nurses and their roles as evidence collectors. Participants differed in their opinions of whether they were advocates or not in this capacity. SANEs talked about breaking the rules and caring about some patients even when they …


Developing Strategic Interventions To Reduce Cardiovascular Disease Risk Among Law Enforcement Officers: The Art And Science Of Data Triangulation, Sandra Ramey, Nancy Downing, A. Knoblauch Sep 2012

Developing Strategic Interventions To Reduce Cardiovascular Disease Risk Among Law Enforcement Officers: The Art And Science Of Data Triangulation, Sandra Ramey, Nancy Downing, A. Knoblauch

Nancy R Downing

The purpose of this study was to use data triangulation to inform interventions targeted at reducing morbidity from cardiovascular disease (CVD) and associated risk factors among law enforcement officers. Using the Precede-Proceed Health Promotion Planning Model, survey data (n = 672) and focus group data (n = 8 groups) from the Milwaukee Police Department were analyzed. Narrative transcripts disclosed that law enforcement officers encounter potential barriers and motivators to a healthy lifestyle. Survey results indicated rates of overweight (71.1% vs. 60.8%) and hypertension (27.4% vs. 17.6%) were significantly (p < or = .001) higher among Milwaukee Police Department law enforcement officers than the general population of Wisconsin (n = 2,855). The best predictor of CVD was diabetes (p = .030). Occupational health nurses are uniquely positioned to identify health risks, design appropriate interventions, and advocate for policy changes that improve the health of those employed in law enforcement and other high-risk professions.


Couples' Attributions For Work Function Changes In Prodromal Huntington Disease, Nancy Downing, Janet Williams, J. Paulsen Sep 2012

Couples' Attributions For Work Function Changes In Prodromal Huntington Disease, Nancy Downing, Janet Williams, J. Paulsen

Nancy R Downing

People who have tested positive for the expanded Huntington disease (HD) gene who are not yet diagnosed (pre-HD) and their companions report subtle changes in ability of people with pre-HD to do their jobs. However, it is not known whether they attribute these changes to HD. Semi-structured telephone interviews were analyzed from seven persons with pre-HD at different estimated points from diagnosis and six companions. Data were analyzed using qualitative analysis methods. Participants made attributions related to health, work, and temperament. Only one participant attributed a change to HD. The process of forming attributions was demonstrated through symptom monitoring and …


Milwaukee Police Department Retirees: Cardiovascular Disease Risk And Morbidity Among Aging Law Enforcement Officers, Sandra Ramey, Nancy Downing, W. Franke Sep 2012

Milwaukee Police Department Retirees: Cardiovascular Disease Risk And Morbidity Among Aging Law Enforcement Officers, Sandra Ramey, Nancy Downing, W. Franke

Nancy R Downing

This study explored the self-reported prevalence of cardiovascular disease (CVD) and accompanying risk factors among 165 male retirees 43 years and older (M = 56.2, SD = 7.1) from the Milwaukee Police Department (MPD) compared to 671 individuals of similar age and income who responded to the 2005 Wisconsin Behavioral Risk Factor Surveillance System (BRFSS). CVD and other risk factors were more prevalent in the MPD retirees than the general population (CVD 15.2% vs. 9.5%, p = .036; hypertension 51.5% vs. 36.2%, p = .001; hypercholesterolemia 62.4% vs. 44.4%, p = .001; overweight and obesity 85.1% vs. 74.7%, p = …


Relationship Of Cardiovascular Disease To Stress And Vital Exhaustion In An Urban, Midwestern Police Department, Sandra Ramey, Elena Perkhounkova, Nancy Downing, Kennith Culp Sep 2012

Relationship Of Cardiovascular Disease To Stress And Vital Exhaustion In An Urban, Midwestern Police Department, Sandra Ramey, Elena Perkhounkova, Nancy Downing, Kennith Culp

Nancy R Downing

This study explored risk factors for cardiovascular disease (CVD) among 336 officers of a Midwestern police force. Instruments used included the Perceived Stress Scale, the Maastricht Questionnaire (measuring vital exhaustion), and a general Health Risk Appraisal. Rates of CVD, hypertension, and hypercholesterolemia were 3%, 28%, and 43%, respectively. The relative risk of hypercholesterolemia for male officers, compared to female officers, was 1.98 (95% confidence interval [CI], 1.10 to 3.56). The officers' average body mass index was 28.6 (SD = 4.9), with 80% being overweight or obese. The average vital exhaustion score was higher for female officers than male officers (p …