Medicine and Health Sciences Commons^™

Reciprocal Control Of Obesity And Anxiety-Depressive Disorder Via A Gaba And Serotonin Neural Circuit, Guobin Xia, Yong Han, Fantao Meng, Yanlin He, Dollada Srisai, Monica Farias, Minghao Dang, Richard D Palmiter, Yong Xu, Qi Wu

Children’s Nutrition Research Center Staff Publications

The high comorbidity between obesity and mental disorders, such as depression and anxiety, often exacerbates metabolic and neurological symptoms significantly. However, neural mechanisms that underlie reciprocal control of feeding and mental states are largely elusive. Here we report that melanocortin 4 receptor (MC4R) neurons located in the dorsal bed nucleus of the stria terminus (dBNST) engage in the regulation of mentally associated weight gain by receiving GABAergic projections from hypothalamic AgRP neurons onto α5-containing GABA

Covid-19 And Mental Well-Being Of Nurses In A Tertiary Facility In Kenya, Sayed Karar, Jasmit Shah, Zohray Talib

Internal Medicine, East Africa

Background: The 2019 coronavirus disease (COVID-19) epidemic is a global health emergency which has been shown to pose a great challenge to mental health, well-being and resilience of healthcare workers, especially nurses. Little is known on the impact of COVID-19 among nurses in sub-Saharan Africa.

Methods: A cross sectional study was carried out between August and November 2020 among nurses recruited from the Aga Khan University Hospital, Nairobi. The survey questionnaire consisted of six components- demographic and work title characteristics, information regarding care of COVID-19 patients, symptoms of depression, anxiety, insomnia, distress and burnout, measured using standardized questionnaires. Multivariable logistic …

The Co-Regulatory Effects Of Emotionally Focused Therapy, Julia Conroy

Graduate Theses and Dissertations

Mental health literature emphasizes the necessity of expanding emotional regulation to improve symptomology of a variety of mental health disorders. Coregulatory experiences have been shown to expand individual emotional regulation and are more likely in relationships with secure attachment. Emotionally Focused Therapy (EFT) is focused on developing secure attachment between partners. This study examined the coregulatory effects of EFT with a single couple over the course of couples’ counseling. The participating couple received eight couples’ counseling sessions from a clinician who is a certified EFT trainer, supervisor, and therapist while having their heart rate, electrodermal activity, and skin temperature taken …

Intermittent Hypoxia And Effects On Early Learning/Memory: Exploring The Hippocampal Cellular Effects Of Pediatric Obstructive Sleep Apnea, Arvind Chandrakantan, Adam C Adler, Mehmet Tohsun, Farrah Kheradamand, Russell S Ray, Steven Roth

Faculty, Staff and Students Publications

This review provides an update on the neurocognitive phenotype of pediatric obstructive sleep apnea (OSA). Pediatric OSA is associated with neurocognitive deficits involving memory, learning, and executive functioning. Adenotonsillectomy (AT) is presently accepted as the first-line surgical treatment for pediatric OSA, but the executive function deficits do not resolve postsurgery, and the timeline for recovery remains unknown. This finding suggests that pediatric OSA potentially causes irreversible damage to multiple areas of the brain. The focus of this review is the hippocampus, 1 of the 2 major sites of postnatal neurogenesis, where new neurons are formed and integrated into existing circuitry …

The Effects Of Mental Illness On Capital Sentencing In The State Of Oregon, Mirtill E. Csikos

University Honors Theses

There is emerging awareness on the potential arbitrariness and unconstitutionality of executing persons with mental illness. Most states with current death penalty laws have little to no protection for severely mentally ill defendants during capital trials. The present paper looked at the effectiveness of sentencing statutes serving the purpose of protecting defendants with severe mental illness in the state of Oregon. Through a careful meta-analysis this research focused on determining how mental illness plays into death penalty decisions and if Oregon’s Guilty Except for Insanity defense provides sufficient protection. Furthermore, the question of mental illness as a mitigating factor was …

Site Supervisors' Perspectives On Supervision Of Counselor Trainees In Integrated Behavioral Health (Ibh) Settings: A Q Methodology Approach, Yeşim Giresunlu

Counseling & Human Services Theses & Dissertations

Integrated Behavioral Health (IBH) is an integrated care approach where primary care and mental health providers work together to address the medical and behavioral health needs of the patients, or clients (Unützer et al., 2012). An increasing number of clinical mental health counselors are providing services in IBH settings and experiencing challenges with navigating unique aspects of their work in these complex systems. Clinical supervision in these settings appears as a critical resource for mental health counselor trainees (supervisees). However, we have very limited knowledge on clinical supervision provided to supervisees at IBH settings. An exploration of site supervisors’ supervision …

Effect Of A 2-Week Relaxing Music Intervention On Anxiety, Stress, And Gut Symptoms In Aerobic Exercisers, Halie Marisa Maass

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to determine the impact of a two-week relaxing music intervention on stress, anxiety, and gastrointestinal (GI) symptoms in exercisers with at least mild anxiety and exercise-related GI symptoms. Block randomization was used to allocate 15 women and two men into control (n = 8) or intervention (n = 9) groups following a one-week baseline. During the baseline period, participants recorded details of their aerobic exercise sessions and discomfort with GI symptoms (nausea, regurgitation/reflux, stomach fullness, bloating, abdominal cramps, gas, the urge to defecate). Following randomization, both groups tracked these same details for two additional …

Injury-Related Fear In Individuals With Chronic Ankle Instability, Ashley Marie Brawford Suttmiller

Rehabilitation Sciences Theses & Dissertations

About 40% of individuals who suffer a lateral ankle sprain develop chronic ankle instability (CAI). The mechanisms for developing CAI is believed to be multi-factorial, however, most literature has focused on the physical manifestations of the condition, leaving our understanding of psychological manifestations of the condition fairly unclear. Injury-related fear has been identified as a psychological factor that may be relevant to the condition, but our understanding is limited. Therefore, the purpose of this dissertation was to better understand injury-related fear in patients with CAI through three studies.

The first study systematically reviewed the literature to understand differences in injury-related …

Policy Development: Stress Management And Critical Incident Debriefing, Karen Loraine Hasie Rowland

Electronic Theses and Dissertations

Abstract Workplace stress and associated disorders (occupational burnout, compassion fatigue, secondary traumatic stress, critical incident stress, posttraumatic stress disorder, etc.) disproportionately affect healthcare workers, especially those working in critical care and emergency environments. The financial cost of stress related after-effects experienced by health care workers exceeds $191 billion each year and includes the cost of associated decreased quality of patient care, missed diagnoses, medical errors, and sentinel events leading to patient disablement or mortality. Mental health interventions such as stress management education and critical incident debriefings have been proven effective in reducing workplace stress and building personal resilience. A gap …

From The President: At The Intersection Of Mission And Service

DePaul Magazine

DePaul's president announces a joint effort with Sinai Chicago to create community-driven, applied research institute to address health inequities in Chicago. He also announces that he will retire as DePaul president on June 30, 2022.

Starting Triple Oral Hypoglycemic Agent Therapy In Poorly Controlled Type 2 Diabetes Is A Suitable Therapeutic Strategy To Lower Hba1c When Insulin Therapy Is Not Desired, Mara A. Darian

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using:

Søfteland E, Meier JJ, Vangen B, Toorawa R, Maldonado-Lutomirsky M, Broedl UC. Empagliflozin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Linagliptin and Metformin: A 24-Week Randomized, Double-Blind, Parallel-Group Trial. Diabetes Care. 2016;40(2):201-209. https://doi.org/10.2337/dc16-1347

for a patient with uncontrolled type 2 diabetes on metformin and sitagliptin and hesitant to begin insulin therapy.

An Investigation Of Occupational Therapy Utilizing Sensory Modulation To Manage Co-Morbid Chronic Pain And Substance Use In Order To Promote Occupational Performance And Recovery, Claire Ruth

Student Capstone Papers

Background: Those with chronic pain have worse drug and alcohol treatment outcomes and higher rates of relapse compared to those without pain or with reduced pain (Ilgen et al., 2020).

Methods: A descriptive study was employed with the aim of determining what are the sensory processing pattens of those with co-morbid chronic pain and in recovery for substance use. All participants completed the Adolescent and Adult Sensory Profile, the Brief Pain Inventory, and the Personal Recovery Outcome Measure (PROM).

Results: From the preliminary findings, individuals with co-morbid chronic pain and substance use may have atypical sensory processing …

Pregnancy And Substance Use, Elise Withers, Krista Thompson, Emily Hamilton, Maren Wright Voss

All Current Publications

The use of alcohol and other harmful substances, such as cocaine, opioids, and marijuana during pregnancy has increased over the last decades (Sebastiani et al., 2018). Using these substances can be very harmful to the unborn baby and mother (Viteri et al., 2015). This fact sheet covers (1) the consequences of substance use and (2) the current recommendations for substance use during pregnancy.

Compassionate Indifference, Judith Sullivan

Journal of Transformative Touch

ABSTRACT

How to turn a not-so-good treatment into an excellent treatment with presence, relaxation and compassionate indifference.

A Multi-Faceted Approach To Understanding Acceptability Of Docs K-5: A Qualitative Analysis, Andrea Guarnieri

USF Tampa Graduate Theses and Dissertations

This qualitative study investigated the acceptability of DOCS K-5, a behavior parenting program adapted for parents of elementary aged children. Despite proven efficacy in preventing maladaptive behaviors, parenting programs have historically suffered from low attendance and engagement. Participants (N = 13) attending the pilot DOCS K-5 program took part in six group interviews while enrolled in the program to examine the facilitators and barriers to attendance, perceived effectiveness, and collateral benefits received from participation in the program. This study considered possible cognitive, affective, instructional, and pragmatic facilitators or barriers to attendance and engagement. Participants described motivations to learn various types …

Personal Mastery And All-Cause Mortality Among Older Americans Living With Diabetes, Ho-Jui Tung, Ming-Chin Yeh, Randall Ford, Gulzar H. Shah

Health Policy & Community Health: Faculty Publications

Introduction: Higher personal mastery is associated with better physical functioning, wellbeing, and longevity among older populations. However, few studies have focused on whether personal mastery is protective against mortality among older adults living with diabetes over time.
Methods: A total of 1,779 participants were identified from an off-year survey of the Health and Retirement Study. Proportional Hazard Models were used to evaluate the significance of selected variables in predicting the survival of participants over a 13-year period.
Results: A substantial proportion (46.7%) of the diabetic patients had survived by the end of 2016. Adults with lower mastery …

Youth Mental Health First Aid: Educators’ Knowledge, Attitudes, Skills, Aspirations, And Behaviors Change And Differences, Alexis M. Sanchez

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to examine educator outcomes related to Youth Mental Health First Aid (Y-MHFA) professional development training. Educator outcomes in knowledge, attitudes, skills, aspirations, and behaviors (KASAB) were examined to evaluate the preparedness of educators to provide mental health support and the effectiveness of Y-MHFA. Additionally, this study aimed to assess educator outcomes depending on their role in the schools, including school-based educators, school-based mental health staff, and administration/district staff. The author conducted a secondary analysis of pre- and post-test questionnaires of 459 educators in a southeastern state of the United States. A repeated measures ANOVA, …

Perceived Benefits Matter The Most In Covid-19 Preventive Behaviors: Empirical Evidence From Okara District, Pakistan, Gulzar H. Shah, Ansar Ali Faraz, Hina Khan, Kristie Cason Waterfield

Health Policy & Community Health: Faculty Publications

The 2019 coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus has affected the social determinants of health, worsening health inequities and deteriorating healthcare capacities around the globe. The objective of this study is to investigate the COVID-19 prevention behaviors within the framework of the Health Belief Model in the city of Depalpur in the Okara District of Pakistan in May 2020. Using an observational, cross-sectional, and quantitative study design, a faceto- face field survey was conducted during the epidemic of COVID-19 in district Okara, Pakistan. A sample of 500 adults was selected from the city of Depalpur the in Okara …

Telehealth Best Practice: A Call For Standards Of Care, Donna S. Sheperis, Arielle Smith

Journal of Technology in Counselor Education and Supervision

Teletherapy is an approach to working with clients that mental health providers have used in some form for years. However, the onset of COVID forced the provision of therapy into teletherapy almost exclusively for a period of time. Currently, mental health providers conducting therapy virtually are not required to be trained in telehealth and are operating without consistent uniform standards of practice. This manuscript pulls from the current literature and guidelines across counseling, psychology, psychiatry, family therapy, and social work to provide a Proposed Standards of Practice for Telehealth. Such standards benefit mental health counselor by grounding practice in common …

Social Determinants Of Health And Care Outcomes Among People With Hiv In The United States, Timothy W. Menza, Lindsay K. Hixson, Lauren E. Lipira, Linda Drach

Regional Research Institute for Human Services

Fewer than 70% of people with HIV (PWH) in the United States have achieved durable viral suppression. To end the HIV epidemic in the United States, clinicians, researchers, and public health practitioners must devise ways to remove barriers to effective HIV treatment. To identify PWH who experience challenges to accessing health care, we created a simple assessment of social determinants of health (SDOH) among PWH and examined the impact of cumulative social and economic disadvantage on key HIV care outcomes.

Understanding The Stigma And Feasibility Of Opening A Safe Injection Facility In Baltimore City: A Qualitative Case Study, Timothy Dupree, Caroline I. Wood, Andrea M. Brace

The Qualitative Report

Supervised injection facilities (SIFs) are medically supervised facilities designed to provide a hygienic environment in which drug users can consume illicit drugs intravenously. SIFs can be cost saving, help to reduce transmission of disease, and decrease drug overdoses. There are no SIFs in the United States. In this study we used a multiple case study design to understand the stigma surrounding the use of a SIF and the feasibility of implementing the drug prevention strategy in Baltimore City by comparing experiences with opening a SIF in Sydney, Australia. We interviewed one healthcare worker at the Sydney SIF and ten community …

Staying At Home: How Well Did Americans Maintain Their Health Behaviors During Covid-19?, Michael Serrur, James Rose

Population Health Research Brief Series

The COVID-19 pandemic has taken a major toll on people's sense of schedule. Lack of motivation and the removal of daily routines has negatively affected health behaviors, leading to an increase in snacking and sitting around the house more frequently than before the pandemic. This brief summarizes the findings from a national survey aimed at understanding behavior change and goal setting during the pandemic and provides tips for getting back into healthy habits.

Demographics, Activities, And Environmental Factors Impact Burnout In A National Survey Of Emergency Medicine Residents, Nicole Battaglioli, Tim P. Moran, Simiao Li-Sauerwine

Journal of Wellness

Introduction: Burnout in emergency medicine and in residency training has been well-described. The impact of demographic, individual, and programmatic factors on burnout have not previously been determined in a national survey of emergency medicine residents. This study aimed to identify personal and environmental factors impacting resident burnout in a national sample of emergency medicine residents.

Methods: A prospective Emergency Medicine Resident Wellness Survey was administered in 2017. We surveyed respondents on demographic, personal, and environmental factors; each respondent also completed the Maslach Burnout Inventory - Human Services Survey. Linear regressions were used to identify variables associated with the Maslach Burnout …

Longitudinal Trauma Treatment Outcomes In An Immigrant And Refugee Sample, Shuen-En Ho

Clinical Psychology Dissertations

Refugee and immigrant populations are at an increased risk of having posttraumatic stress disorder (PTSD) and exhibit a significant amount of variance in trauma treatment outcomes that may be impacted by sociocultural factors. This study examines the impact of demographic variables on treatment outcome and trajectory of PTSD symptoms in a clinic setting with trauma-focused treatments in refugee/immigrant and general populations. Data was collected from the electronic medical record at the Harborview Center for Sexual Assault and Traumatic Stress. A total of 817 participants completed intake, 58 of which self-identified as immigrant/refugee. One-way ANOVAs were conducted to examine group differences …

A Systematic Review Of Mental Illness, Criminogenic Risk, And The U.S. Prison System, Eliza Esquibel

Student Works

The incarceration rates in the United States are the highest in the world. Within the U.S. prison population, mental illness is overrepresented as compared to the general population. The present study examined existing literature that researched the connection between the prison system and mental illness, and the potential solutions to this crisis. The studies looked at focused on psychiatric disorders, substance disorders, and trauma. They also focused on the intersection between race, mental illness, and the prison system, and the intersection between mental illness, gender, and the prison system. These studies revealed a high prevalence of untreated mental illness in …

Coping With Medical School: An Interpretive Phenomenological Study, Sebastian C K Shaw, John L. Anderson

The Qualitative Report

Anecdotal evidence suggested that hopelessness and helplessness (HH) were often reported by undergraduate medical students. It is known that medical students are more susceptible to high levels of stress and depression than other student groups. There is currently concern about suicide rates in students and high drop-out rates in junior doctors. But what can be said of HH within this population? This study was aimed at eliciting medical students’ experiences of HH. An interpretive phenomenological approach was adopted. Participants were recruited from a single medical school. Loosely structured, audio-recorded interviews were carried out. Recordings were then transcribed verbatim, then underwent …

Relationships Between Coping Mechanisms And Perceived Stress Of Portland State University Community Members Amidst Covid-19, Julie Goldman

University Honors Theses

Purpose: The purpose of this study was to assess the coping mechanisms used by the Portland State University (PSU) community and their relationships to perceived stress.

Methods: A virtual survey composed of demographic questions, the Perceived Stress Scale (PSS10), the Brief COPE, and two open-ended questions was distributed to the community. Data were collected from 231 respondents, mostly PSU students. Statistical Package for the Social Sciences (SPSS) was used to compute mean PSS score, adaptive coping score, and avoidant coping score. Pearson correlations and t-tests were run to explore the relationship between perceived stress and coping data.

Results: Perceived stress …

Pregnant Women With Substance Use Disorders Deserve Plans Of Safe Care, Alexandra E. Punch, Monika Taylor

Population Health Research Brief Series

Substance use among women who are pregnant is a growing U.S public health issue. Approximately 340,000 infants are affected by prenatal exposure to illicit drugs annually, leading to an increase in Neonatal Abstinence Syndrome (NAS), and Child Protective Services involvement. This issue brief describes the current state of prenatal substance use and provides guidance on the use of federally mandated Plans of Safe Care to help mothers prepare for the arrival of their baby while navigating their substance use disorder.

Assessment Of Pathogenic Changes In The Gut-Liver Axis In Plwh With Heavy Alcohol Drinking And Gut Dysbiosis Marked By Decreased Butyrogenic Potential., Smita Ghare, Vaughn Bryant, Richa Singhal, Sabina Gautam, Chanakya Charan Tirumala, Andrea Reyes-Vega, Craig J. Mcclain, Ronald Cohen, Varand Govind, Robert L. Cook, Shirish Barve

Faculty and Staff Scholarship

Purpose: People living with HIV infection (PLWH) experience increasing risk for non-AIDS diseases including liver dysfunction and injury. Both HIV-infection and heavy alcohol drinking (HAD) are known to cause gut microbial dysbiosis and systemic inflammation that may potentially contribute to altered Gut-Liver axis. However, the specific pathogenic features associated with combinatorial harmful effects of alcohol and HIV infection on gut-liver interactions are not completely understood. This study evaluate the pathogenic changes in the Gut-Liver axis in PLWH with HAD.

Effects Of Social Technology On Older Adults In A Residential Living Facility, Katherine Bennett, Mia L. Gonzalez, Sydney L. Harper, Madison N. Logan, Kaeli M. Jeffers, Alexandrea C. Springer, Jeanne Sowers

Student Journal of Occupational Therapy

Personal connection and social interaction are vital components of health throughout the lifespan. Loneliness and social isolation among the older adult population impacts both physical and mental health negatively. Analysis of published research demonstrates the importance of considering the use of different social technology platforms to foster opportunities for social support among family and friends. Researchers noted an increased relevance of the need for social technology in residential living facilities with the emergence of the COVID-19 pandemic and social distancing. The study aims to investigate the impact of social technology, via Sherish℠ Connect on older adults’ reported levels of loneliness …