Medicine and Health Sciences Commons^™

Fact Sheet For Parents: What To Know About Zyn Nicotine Pouches, Aaron Hunt, Gabriela Murza, Alyssa Ferrin

All Current Publications

This fact sheet provides information about ZYN, which is a nicotine pouch becoming commonly used among youth due to social media advertising. This fact sheet will help parents understand the impact of ZYN pouches and approaches to monitor, prevent, and address use among youth.

Naloxone: A Lifesaving Tool Against Opioid Overdose, Aaron Hunt, Gabriela Murza, Amy May, Jenna Hawks, Alyssa Ferrin

All Current Publications

Naloxone is a medicine that can temporarily stop an opioid overdose by blocking the effects of opioids on the brain, which can save a person's life. This fact sheet explains why naloxone is important and safe, how to recognize the signs of opioid overdose, and how to obtain, store, and administer naloxone. Naloxone training is also available through Utah State University Extension.

Supporting Elementary Educators Through A Nervous System Regulation And Social-Emotional Learning Skills Workshop Intervention: An Musc Capstone Project, Lily Morgan

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Teachers have a great influence on developing children’s emotional intelligence, regulatory capacity, and occupational engagement. These professionals also happen to report some of the highest rates of stress, mental health challenges (Agyapong, B. et al, 2022), and burnout (Xie, M., et al, 2022). Providing teachers with education and support on nervous system regulation, social-emotional learning skills, and related topics can improve their ability to manage job stress, enhance modeling and interactions with students, and improve their quality of life. This project aimed to enhance knowledge, provide access to resources, and serve to support elementary educators at an inner-city school in …

Web-Based Wellness, Katherine Shipers

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Adults of all ages experience life stressors and transitions that impact their physical, emotional, and psychosocial wellness. Despite a recognized need for self-improvement, many adults face time constraints that limit their ability to engage in traditional wellness activities. Research suggests that micro-learning strategies—brief, targeted educational interventions—can effectively enhance knowledge and influence life practices.

This quality improvement capstone project explored the use of microlearning to support adult well-being by developing a web-based, modular learning system. The project implemented a series of short educational videos addressing various wellness topics, supplemented by corresponding worksheets and resource materials. Designed for asynchronous completion, these wellness …

A New Paliperidone Palmitate Formulation: How Is It Different And Where Does It Fit In Our Array Of Choices For Long-Acting Formulations Of Risperidone And Paliperidone?, Justin Faden, Leslie Citrome

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Long-acting injectable (LAI) antipsychotics have been shown to enhance treatment adherence and outcomes in individuals with schizophrenia, schizoaffective disorder, and bipolar disorder. In recent years, the U.S. Food and Drug Administration (FDA) has approved several LAIs with differing amenities of care, such as mode of administration, duration of oral medication supplementation, dosing frequency, needle gauge and size, and injection volume, amongst others. Additionally, several LAIs are distinct formulations of risperidone and paliperidone, making it difficult to distinguish between formulations, and many providers are unfamiliar with these newer agents. In 2024, a once-monthly LAI formulation of paliperidone palmitate, manufactured by Luye …

Social Health Among Adolescents In The Global School-Based Student Health Survey (Gshs), Luke Pontoriero, Sarah Simon, Lauren Anderson

Seaver College Research And Scholarly Achievement Symposium

Background: Social health is a function of the quantity and quality of relationships, including with family members and peers. Adolescents who report being lonely or having no close friends have a low quantity of relationships, and those who feel that their peers are unkind and their parents are not understanding have low quality relationships. We examined whether poor social health is associated with violent behavior.

Methods: We analyzed data from the Global School-based Student Health Survey (GSHS), which employs a standardized two-stage cluster sampling method and a validated questionnaire to explore health and risk behaviors among nationally representative samples of …

Combating The Impact Of Adverse Childhood Experiences On Self-Esteem And Emotion Regulation: An Art-Based Intervention Program, Kaileigh Kirk, Cynthia Haynes

Spring 2025 OTD Capstone Symposium

This poster presents an art-based intervention program developed and designed to positively impact self-esteem and emotion regulation in children with Adverse Childhood Experiences (ACEs) through evidence-based intervention activities and group discussions. This program was created with the hopes of expanding occupational therapy's knowledge and utilization of potential interventions for children with ACEs.

Support Group Development For The Mental Health Of Parents Of Children With Complex Diagnoses, Sarah G. Bonner, Lakesia Boykin, Dana Madalon

Spring 2025 OTD Capstone Symposium

This presentation covers support group program development for the mental health of parents of children with complex diagnoses. It outlines the need for emotional support, describes the group activities used to promote coping and resilience, and explains how the program was implemented and evaluated using pre- and post-surveys.

The Intersecting Association Of Speaking A Non-Dominant Language And Lower Healthcare Access On Self-Reported Depression Among U.S. Adults: A Cross Sectional Study Using Nhanes Data (2015-March 2020), Vincenzo J. Cornacchione, Corey Linver

OHSU-PSU School of Public Health Annual Conference

Objective: This analytic study examined the joint and independent associations between language preferences and healthcare access on moderate to severe depression among non-institutionalized adults living in the U.S., using data from the 2015 to March 2020 National Health and Nutrition Examination Survey (NHANES).

Methods: In this cross-sectional study design, we analyzed a nationally representative data set comprised of 11,051 participants. Multivariable logistic regression models were used to estimate the joint and independent associations between our dual exposures and moderate to severe depression, adjusting for key demographic variables based on our theoretical framework. We created categorical measures of preferred language (speaking …

Evaluating The Effectiveness Of A Non-Pharmacological Sleep Bundle For The Prevention Of Delirium In Geriatric Patients In The Intensive Care Unit: A Scoping Review, Morgan Wilkins Bsn, Rn, Vanessa D'Amico Bsn, Rn, Alyssa Goyda Bsn, Rn, Seema Janga Bsn, Rn, Kaylin Story Bsn, Rn, Tracy Mcclinton Dnp, Aprn, Agacnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background

Delirium is an acute disorder yielding cognitive deficits, such as disruption in attention and awareness. It impacts approximately 50% of individuals over the age of 65 who are admitted to the hospital and is prevalent with patients in the intensive care unit (ICU). ICU delirium is associated with adverse outcomes, including higher morbidity, prolonged hospital stays, and chronic neurocognitive deficits. Research demonstrates that implementation of a non-pharmacological sleep bundle can reduce the overall occurrence of delirium. The purpose of this scoping review is to examine the efficacy of a non-pharmacological sleep bundle on the incidence of ICU delirium in …

Education About Eds: How Can Colleges Reduce The Risk And Prevalence Of Eating Disorders In Ncaa Female Athletes?, Meghan J. Mcnabb, Alexandra Jakubiak

Department of Nutrition Student Projects

Female collegiate athletes are currently recognized as a high-risk group for developing eating disorders due to performance pressures and unrealistic body standards. Limited studies have analyzed the impact of tailored educational and behavioral interventions on the prevalence of eating disorders among female athletes in the National Collegiate Athletic Association (NCAA). This proposed research will be conducted at Nova Southeastern University to explore how colleges can decrease the cases of eating disorders among female athletes using a multi-component educational intervention. Participants will be screened through the EAT-26 assessment tool and initial BMI measures will be recorded to establish a baseline for …

Hdac5 Enzymatic Activity Regulates Scn4b Expression To Control Relapse-Like Cocaine Seeking, Daniel J. Wood

MUSC Theses and Dissertations

Substance Use Disorder (SUD) is a relapsing disorder characterized by repeated seeking and use of psychoactive substances despite negative consequences to the individual. Epigenetic changes within the medium spiny neurons (MSNs) of the nucleus accumbens (NAc) are thought to underly the lasting propensity to relapse in SUD. The epigenetic enzyme histone deacetylase 5 (HDAC5) in NAc MSNs limits the formation of reward-cue associations in rodent models of drug seeking, but not sucrose seeking, leading to decreased relapse-like behavior. However, whether HDAC5 reduces drug seeking behavior through its own deacetylase activity or through the recruitment of co-repressors is unknown. Furthermore, these …

Cell Type-Specific Multi-Omics Analysis Of Cocaine Use Disorder In The Human Caudate Nucleus, Lea Zillich, Annasara Artioli, Veronika Pohořalá, Eric Zillich, Laura Stertz, Hanna Belschner, Ammar Jabali, Josef Frank, Fabian Streit, Diana Avetyan, Maja P Völker, Svenja Müller, Anita C Hansson, Thomas D Meyer, Marcella Rietschel, Julia Ladewig, Rainer Spanagel, Ana M M Oliveira, Consuelo Walss-Bass, Rick E Bernardi, Philipp Koch, Stephanie H Witt

Faculty, Staff and Student Publications

Structural and functional alterations in the brain's reward circuitry are present in cocaine use disorder (CocUD), but their molecular underpinnings remain unclear. To investigate these mechanisms, we performed single-nuclei multiome profiling on postmortem caudate nucleus tissue from six individuals with CocUD and eight controls. We profiled 30,030 nuclei, identifying 13 cell types including D1- and D2-medium spiny neurons (MSNs) and glial cells. We observed 1485 differentially regulated genes and 10,342 differentially accessible peaks, with alterations in MSNs and astrocytes related to neurotransmitter activity and synapse organization. Gene regulatory network analysis identified transcription factors including ZEB1 as exhibiting distinct CocUD-specific subclusters, …

Substance Abuse On Vulnerable United States And Russian Populations, Avery Wuollet, Emyli Sandrock, Mallory Loerts, Rylyn Murphy

INSPIRE Student Research and Engagement Conference

The National Institute of Health states that 39.5 million people in the world are affected by drug abuse. According to the National Institute of Health, a total of 18,013 overdose deaths in Russia, while nearly 108,000 people have overdosed in the United States as of 2024, according to The National Institute of Drug Abuse. This is prevalent due to poor policies, the presence of street drugs, and the stigmas surrounding this problem. This research will entail the different effects drug abuse has on both users and the community. The research will also compare the risks of engaging in drug abuse …

Implementing Self-Regulation Practice And Handouts For Parents And Educators At Linden Waldorf School For The Neurodivergent Student Population​, Samantha Thompson

OTD Capstone Projects

This doctoral capstone project was completed through a partnership with Linden Waldorf School in Nashville, TN. The invention, application, and advocacy of occupational therapy approaches for the neurodivergent student population were the main objectives of this research. This project aimed to empower Linden Waldorf educators and staff to more effectively address the needs of their kids by offering direct observations, educational presentations, and a range of educational resources on an assortment of neurodivergent deficits and diagnoses. Executive dysfunction, attention deficit hyperactivity disorder, difficulties with emotional regulation, autistic spectrum disorders, and anxiety are among the diagnoses and deficiencies discussed in this …

Examining Physiological Responses To Misophonic Triggers, Christian O'Reilly, Xuan Yang, Sewon Oh, Doug Wedell, Svetlana Shinkareva

Faculty Publications

We collected and analyzed an array of biosignals (face electromyogram, skin electrodermal activity, peripheral temperature, and electrocardiogram) in 60 participants with and without misophonia, a condition characterized by decreased tolerance to innocuous sounds. Our goal was to objectively characterize the physiological response to misophonia triggering sounds. We found that misophonic responses can be objectively identified in some cases through atypical physiological reactions to triggering stimuli, though not all participants exhibited this response. Our analyses suggest a large interindividual variability in response to misophonic triggers and highlights the need for methodological adjustments in future experiments to increase the detectability of misophonic …

74 - Age And Seasonal Blood Pressure Variation In People Experiencing Homelessness In Hampton Roads, Luke Ekdahl, Katherine Schaffer, Joshua Edwards, Kean Feyzeau

Undergraduate Research Symposium

Intro: For older community members experiencing homelessness, both their housing status and age are associated with increased cardiovascular risk. Lack of consistent protection from outdoor temperatures are hypothesized to affect variation in blood pressure seasonally. In this study, we sought to compare older (55+) and younger (under 55) individuals in this cohort and identify within-group associations between blood pressure (BP) and mean daily temperature (MDT) as affected by season.

Methods: 301 patients from two student-run free clinics met BP inclusion criteria. MDT was sourced from the Global Historical Climatology Network daily dataset. Interquartile range method for outlier detection limited visits …

Supporting Maternal Mental Health In The Postpartum Period With The Use Of Home Resource Kit, Nicole Craig

Theses and Graduate Projects

Postpartum mental health disorders, including postpartum depression and anxiety, can affect a significant proportion of new mothers for centuries. This paper explores the development, implementation, and evaluation of an at-home mental health resource kit designed to support maternal mental health while navigating the stresses of new motherhood. Utilizing Jean Watson's Theory of Human Caring as a theoretical framework, the study assesses the effectiveness of integrative therapies such as aromatherapy, mindful meditation, and educational resources in managing postpartum stress. Data collected through pre- and post-surveys and roundtable discussions provide insights into the benefits and limitations of these interventions. The findings indicate …

A Cross-Sectional Analysis: Employment And Its Impact On Physical Activity, Academic Performance, And Quality Of Life Among Bellarmine University Students, Orlando Exposito Nuñez

Undergraduate Theses

Introduction: Half of undergraduate students are employed, meaning they must balance work with academics, physical activity (PA), and personal responsibilities. This study examines the potential negative impact of employment on PA, academic performance, and quality of life (QOL) among college students. Methods: The cross-sectional survey comprised 125 Bellarmine University students (Age 21.07 ± 3.40; 52% female, 48% male). Measures included the RAND SF-36 for QOL, the International Physical Activity Questionnaire Short Form (IPAQ-SF), and a custom academic and employment questionnaire. Racial and ethnic demographics included White (75.2%), Black or African American (11.2%), Hispanic or Latino (15.2%), Asian (4.8%), Multiracial (4.8%), …

The Effectiveness Of Gad-7 Screening In High School Students, Tamara L. Smith, Allison Darnell, Margaret Harvey, Phd, Acnp-Bc, Chfn, Jacqueline Sharp Dnp, Aprn, Pmhp-Bc

Doctor of Nursing Practice Projects

Purpose/Background

Adolescent mental health is a growing concern, with anxiety disorders being particularly prevalent among high school students. Left untreated, anxiety can significantly impact academic performance, social functioning, and long-term mental health. The COVID-19 pandemic exacerbated these challenges, highlighting the critical need for effective screening and intervention strategies. The Generalized Anxiety Disorder 7-item scale (GAD-7) is a validated tool for identifying anxiety disorders, yet its application in high school settings is limited. This scoping review explores the effectiveness of GAD-7 in increasing mental health referrals and improving anxiety outcomes in high school students.

Methods

A comprehensive search was conducted across …

Blue Chairs And Broken Minds: The Troubled Teen Industry’S Legacy Of Abuse, Macie Barker '25

Honor Scholar Theses

The Troubled Teen Industry (TTI) operates under the veil of rehabilitating adolescents with behavioral challenges. However, evidence reveals a system rife with abuse, manipulation, and inadequate oversight. From the infamous blue chairs of Straight, Inc., to the isolation tactics of WWASP program, this industry has maintained a facade of treatment while subjecting youth to severe abuse. This paper explores the history, recruitment tactics, institutional failures, survivor recovery journeys, and legal battles that define the TTI. Advocacy movements, including Breaking Code Silence and WWASP Survivors, have emerged to combat industry malpractice and push for policy changes to protect vulnerable youth. Additionally, …

Protocol For A Multisite, Observational Clinical Study Of The Association Between Skin Colour And Pulse Oximeter Accuracy In Children Undergoing Cardiac Catheterisation (Pach Study), Halley Ruppel, Liming Huang, Christopher J Petit, Athar M Qureshi, Christopher P Bonafide, Elizabeth E Foglia, Jeffery Feldman, Meghan B Lane-Fall, Jennifer M Lynch, Anna Chien, Michelle Dunn, Michael L O'Byrne

Faculty, Staff and Students Publications

Introduction: Prospective, real-world clinical studies of the association between skin color and pulse oximeter (SpO2) accuracy in children are needed to address the limitations of previous research. Such studies are essential for generating evidence for clinicians, regulators and industry. This is the protocol for a multisite study funded by the National Heart, Lung, and Blood Institute (R01HL171313; 1 January 2024-31 December 2028).

Methods and analysis: In this pragmatic, observational study conducted in three large paediatric cardiac catheterisation centres in the USA, children undergoing cardiac catheterisation with directly measured arterial oxygen saturation will be prospectively enrolled. The outcome variable (SpO2 bias) …

The Impact Of Covid-19 On Nurses' Feelings, Stress, Coping, And Motivation In Palestinian Treatment Centers Of Corona, † Wafaa Menawi, Shatha Mari, Ahmad Adel Hanani

An-Najah University Journal for Research - B (Humanities)

Background: Frontline nurses of COVID-19 found themselves in an unfamiliar new disease work environment, fighting to adapt and control the stress while working at covid-19 centers in Palestine. Aim: To investigate the impact of COVID-19 on nurses' feelings, stress, coping, and motivation in COVID-19 Palestinian treatment Centers. Method: A descriptive cross-sectional design was conducted between Mid of July to the end of October 2021 by recruiting a purposive sample of 390 nurses who worked at the Ministry of Health during COVID-19 pandemic treatment centers. The nurses filled out the COVID-19 Health Personnel Questionnaire with Cronbach's Alpha > 0.9. Results: Palestinian frontline …

Safety And Efficacy Of 112 Mg Intranasal Esketamine In Patients With Treatment-Resistant Depression: A Retrospective Observational Study From Outpatient Community Clinics, Kirsten Brinkmeier, Michael Kritzer, Brandon Doan, Cecilia Li, Nicholas Mischel

Medical Student Research Symposium

This retrospective study examined the safety and efficacy of 56, 84, and 112 mg intranasal (IN) esketamine via medical record review of 24 patients with treatment resistant depression (TRD). Doses ranged from 56 mg to 112 mg and were titrated across sessions to maximize individual response while considering tolerability. Treatment response was defined by reduction in average Patient Health Questionnaire-9 (PHQ-9) scores. Tolerability was defined by blood pressures at baseline, 40 minutes after, and 2 hours after drug administration. Patients ranged from 19 to 60 years old (average 38.87), and 15 (62.5%) were female. Patients received an average of 1 …

Evaluating Engagement In Health Care And Substance Use Disorder Services Among People Who Use Drugs, Tiffany Mckenney, Kevin Cobty, Divya Boorle, Julie Gleason-Comstock

Medical Student Research Symposium

An urban community-based organization conducted a study to examine demographics of individuals who use drugs and their approaches to risk reduction. A substantial proportion reported encountering significant barriers to accessing substance use disorder (SUD) services.

In collaboration with a state survey, the community organization recruited a convenience sample of individuals who actively used drugs, examining substance use patterns, healthcare access, and barriers to SUD services. Community health workers facilitated outreach efforts, focusing on harm reduction engagement, and healthcare access.

Data were collected from 55 individuals. 51% identified as male, 48% as female, and 2% as LGBTQIA+. 67% identified as White/Caucasian, …

The Impact Of Legislation And Implementation Of An Emergency Department Medications For Opioid Use Disorder Program On Buprenorphine Administration, Jacob Manteuffel, Joseph Miller, Nadine Jawad, Alexis Maroney, Revelle Gappy, Nora Sharba, Grant Zydeck

Medical Student Research Symposium

The emergency department (ED) plays a critical role in addressing a wide range of healthcare needs and can be the first point of contact for individuals with opioid use disorder (OUD). Buprenorphine, a partial opioid agonist, is a medication that helps treat OUD. On January 12, 2023, federal changes removed a major barrier, allowing all clinicians to prescribe buprenorphine. Later in 2023, a Medications for Opioid Use Disorder (MOUD) program was implemented in a high-volume free-standing ED. We aimed to review the impact of these changes on buprenorphine administration.

We conducted a retrospective chart review of buprenorphine administration and ICD …

Exploring The Impact Of Social Media And Social Networks On Juvenile Sexual Behavior Problems: A Scoping Review, Shaleen Clay

LSU Master's Theses

The issue of juvenile problematic sexual behavior has become a pervasive problem, and little research exists on the topic. How social media and social networks impact problematic sexual behaviors in juveniles is even less known and understood. The objective of this scoping review was to determine what is known about the impact of social media and social networks on juvenile sexual behavior problems. Four key themes appeared in the literature including the use of adult terminology, rather than juvenile, to describe juvenile relationships; the normalization of abusive behaviors within adolescent relationship; the influence of social networks/peer groups on aggression and …

Evaluating The Efficacy Of Predischarge Referrals In Preventing Emergency Mental Health Hospital Readmissions: A Scoping Review, Pretia Carpenter Bsn, Rn, Stephanie Mays Bsn, Rn, Jacqueline Sharp Dnp, Aprn, Pmhp-Bc, Sharon H. Little, Dnp, Fnp-Bc, Aprn

Doctor of Nursing Practice Projects

Background

Emergency mental health hospital readmissions present significant challenges to healthcare systems, often resulting in increased costs, prolonged hospital stays, and poor patient outcomes. Continuity of care through predischarge referrals to outpatient mental health services, psychosocial support, and community resources has been proposed as a strategy to reduce readmissions. However, the effectiveness of these interventions remains inconsistent across different populations and settings.

Objective

This scoping review aims to evaluate the effectiveness of predischarge referrals in reducing 30-day emergency mental health hospital readmissions, identify key components of successful programs, and assess the influence of demographic factors on readmission rates.

Methods

A …

The Profound Role Of An Adult Survivor Program Adaptive Sports Retreat On Quality Of Life And Self Perception For Adult Burn Survivors, Roselle E. Crombie Md/Mph, Facs, Faba, Theresa E. Abrams Lcsw, Phd, Cindy Rutter Bsn, Lmft, Josh Mishell Ba, Philip E. Fidler Md

Posters

Mental health struggles amongst adult burn survivors has recently been documented as an ongoing need for therapy in peer reviewed journals.1 Although there are many robust programs, camps, reintegration programs and support systems through child life for children, the analogous programs for adults are lacking in comparison to the pediatric ones. Ten years ago, a subset of this author group ran an adult adaptive sports survivor program in conjunction with a national burn meeting. At that time, all the participants, mental health providers and participating surgeons were able to experience the profound impact a program like this can have on …

Profit Over Patients: Examining The Influence Of Pharmaceutical Companies On Mental Health Medication Prescriptions, Allison Beltramini

Honors Projects in Biological and Biomedical Sciences

This paper explores the relationship pharmaceutical companies have with the overprescription of mental health medication, highlighting unethical marketing practices and their impact on prescription patterns. Previous literature addresses unethical pharmaceutical company marketing strategies, relationships within the field, and cost differences. This study includes qualitative insights from professionals in the field. Interviews conducted collected information that showed the prevalence of mental health illnesses, how treatments are prescribed, and the extent of pharmaceutical influence. Initial findings suggest a significant push for medication as it is the most common treatment method for mental health illnesses. This study highlights pharmaceutical companies' profit-driven motives and …