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Full-Text Articles in Medicine and Health Sciences
Intracerebral Hemorrhage After Carotid Endarterectomy, José Biller, Andrew C. Hayes, Fred N. Littooy, William H. Baker
Intracerebral Hemorrhage After Carotid Endarterectomy, José Biller, Andrew C. Hayes, Fred N. Littooy, William H. Baker
Henry Ford Hospital Medical Journal
Intracerebral hemorrhage (ICH) is a rare complication of carotid endarterectomy (CE). In our multicenter series of 1,180 CE (Baker-Littooy), three ICH occurred, of which two were fatal. One patient was receiving anticoagulants because ofa prosthetic aortic valve; another had rupture of a known ipsilateral intracranial aneurysm. Both occurred more than six weeks postoperatively. The third patient, who was hypertensive, had a nonfatal ipsilateral thalamic hemorrhage on the third postoperative day. Though these three patients represent only 0.25% of our series, they constitute 12% of our total strokes. ICH constitutes the largest percentage of nontechnically-related strokes and noncardiac deaths after CE.
Cardiac Papillary Fibroelastoma: A Source Of Coronary Artery Emboli And Myocardial Infarction, Gerald Fine, Shoba R. Pai
Cardiac Papillary Fibroelastoma: A Source Of Coronary Artery Emboli And Myocardial Infarction, Gerald Fine, Shoba R. Pai
Henry Ford Hospital Medical Journal
Cardiac papillary fibroelastomas, although generally small and asymptomatic, have been suspected of being responsible for cerebral accidents, angina, and sudden death. The diagnosis of tumor embolization, considered in a number of cases, has been based on circumstantial evidence in all instances except for one case of sudden death due to embolism to the left anterior descending coronary artery. In all other cases, angina and sudden death have been related to a ball valve-type obstruction of a coronary ostium by tumor. The present case documents tumor embolism to peripheral right coronary arteries with associated, clinically silent myocardial changes.
Infectious Diseases And The Persisting Microbial Challenge, Louis D. Saravolatz
Infectious Diseases And The Persisting Microbial Challenge, Louis D. Saravolatz
Henry Ford Hospital Medical Journal
No abstract provided.
An Overview Of The Newer Antibiotics, Ramon Del Busto
An Overview Of The Newer Antibiotics, Ramon Del Busto
Henry Ford Hospital Medical Journal
The introduction of a large number of new antibiotics has made selecting the one most appropriate for treatment a confusing task for the practicing physician. One problem is that the differences in pharmacokinetics, in vitro activity, and clinical indications between some of these agents may be relatively minor; this is especially true of the new cephalosporins. Another problem is that the generic names of the cephalosporins are so similar that it is impractical, even for the infectious diseases specialist, to be familiar with all of them. This review attempts to summarize the most important characteristics of these new antibiotics and …
Congenital Seminal Vesicle Cyst: A Specific Diagnosis By Computed Tomography, Leo Drolshagen, Michael A. Sandler
Congenital Seminal Vesicle Cyst: A Specific Diagnosis By Computed Tomography, Leo Drolshagen, Michael A. Sandler
Henry Ford Hospital Medical Journal
Computed tomography (CT) has been shown to be of great value in the assessment of the urinary tract. However, this modality has been primarily used in the evaluation of renal masses and the staging of urinary tract carcinomas. It may also be useful in less common abnormalities, such as mesonephric duct anomalies including congenital seminal vesicle cysts. These lesions are associated with renal agenesis and may produce urinary tract symptoms, or be discovered incidentally. We present a case of a congenital vesicle cyst associated with ipsilateral renal agenesis with characteristic CT findings allowing for a specific diagnosis.
Influenza: Prevention And Therapy, William M. Valenti
Influenza: Prevention And Therapy, William M. Valenti
Henry Ford Hospital Medical Journal
No abstract provided.
Viral Hepatitis: Update On Prevention, Miriam J. Alter
Viral Hepatitis: Update On Prevention, Miriam J. Alter
Henry Ford Hospital Medical Journal
No abstract provided.
Prospects For The Medical Use Of Interferon In 1984, Bosko Postic, Julio C. Arroyo
Prospects For The Medical Use Of Interferon In 1984, Bosko Postic, Julio C. Arroyo
Henry Ford Hospital Medical Journal
Interferon, a natural and wide spectrum antiviral polypeptide that was discovered in 1957, has been extensively described. In addition to its antiviral effect, interferon has been found to suppress tumor growth and modulate the immune response. Until 1980, interferon was primarily prepared for clinical trials in human leukocytes derived from the buffy coat of whole blood. A major breakthrough occurred in the late 1970s when human interferon was produced by DNA recombinant methods in such heterologous cells as bacteria (genetic engineering). Interferon is not commercially available in 1984, but it may, based on clinical trials in humans, become part of …
Medical Education In The United States: Some Current Problems And An Uncertain Future, Richard J. Reitemeier
Medical Education In The United States: Some Current Problems And An Uncertain Future, Richard J. Reitemeier
Henry Ford Hospital Medical Journal
No abstract provided.
A Case Of Ige Myeloma: Methodology And Review Of The Literature, Pat A. Allevato, Michael J. Deegan, Jau-Wen Chu, Mary B. Perry, Carolyn L. Barth
A Case Of Ige Myeloma: Methodology And Review Of The Literature, Pat A. Allevato, Michael J. Deegan, Jau-Wen Chu, Mary B. Perry, Carolyn L. Barth
Henry Ford Hospital Medical Journal
A 56-year-old man presented with a one-year history of progressive weakness predominantly affecting his extremities and persistent low back pain. Ouchterlony immunodiffusion of the concentrated urine detected a marked increase in lambda light chains. A sternal bone marrow documented a diagnosis of multiple myeloma. Screening high resolution agarose gel electrophoresis revealed diffuse hypogammaglobulinemia and, retrospectively, an equivocal, faint band which migrated in the fast gamma region. By using a combination of Immunoelectrophoresis and immunofixation electrophoresis, this questionable band was determined to represent an IgE lambda monoclonal protein. Radioimmunoassay for IgE documented a serum concentration of 50.6 mg/dl. No intact IgE …
Rapidly Progressive Pancytopenia, Hepatomegaly, And Abnormal Lung Uptake Of Colloid In Systemic Lupus Erythematosus: Possible Saturation Of Reticuloendothelial System With Blood Elements, Tetsushi Sakurai, Kiyoshi Fukuda, Ichiro Kono, Teizo Kabashima, Kazuhide Yamane, Heihachiro Kashiwagi
Rapidly Progressive Pancytopenia, Hepatomegaly, And Abnormal Lung Uptake Of Colloid In Systemic Lupus Erythematosus: Possible Saturation Of Reticuloendothelial System With Blood Elements, Tetsushi Sakurai, Kiyoshi Fukuda, Ichiro Kono, Teizo Kabashima, Kazuhide Yamane, Heihachiro Kashiwagi
Henry Ford Hospital Medical Journal
A patient with systemic lupus erythematosus developed severe abdominal pain and tender hepatomegaly associated with progressive pancytopenia and elevated serum levels of circulating immune complexes. Liver scintigram demonstrated extreme hepatomegaly with poor colloid uptake and splenomegaly with increased colloid uptake. An unusual accumulation of colloid in the lungs was also noted. Subsequent clinical and laboratory studies raised the possibility of saturation of the reticuloendothelial system in the liver by circulating immune complexes and blood cells, a condition demonstrated in experimental animals, but not hitherto well documented in the human immune complex disorder.
Immunology Of The Acquired Immunodeficiency Syndrome, Patrick W. Mclaughlin, Carl B. Lauter
Immunology Of The Acquired Immunodeficiency Syndrome, Patrick W. Mclaughlin, Carl B. Lauter
Henry Ford Hospital Medical Journal
The Acquired Immunodeficiency Syndrome (AIDS) first recognized in 1981, has been extensively studied, and the most recent studies have demonstrated that its defects extend well beyond the apparent deficient cell-mediated immunity to include humoral immunity, autoimmunity, and abnormal immunoregulation. The recent discovery of a retrovirus, HTLV III, as a possible etiologic agent is discussed in relation to other viruses known to cause immunodeficiency. Simian AIDS, an animal model of virus-induced immunodeficiency, is also discussed. Recommendations are made regarding the interpretation and limitations of immune testing in AIDS, including a discussion of how apparently healthy homosexuals and groups at risk develop …
Tubal Lavage In The Management Of Ectopic Pregnancy, Samuel A. Motanya, William H. Pfeffer, Emile Sandelin, C. James Chuong
Tubal Lavage In The Management Of Ectopic Pregnancy, Samuel A. Motanya, William H. Pfeffer, Emile Sandelin, C. James Chuong
Henry Ford Hospital Medical Journal
No abstract provided.
Editorial, Raymond C. Mellinger
Editorial, Raymond C. Mellinger
Henry Ford Hospital Medical Journal
No abstract provided.
Clinical Trials: I. Design And Ethical Issues, Barbara Tilley
Clinical Trials: I. Design And Ethical Issues, Barbara Tilley
Henry Ford Hospital Medical Journal
No abstract provided.
Why Cancer?, Angelos A. Kambouris
Why Cancer?, Angelos A. Kambouris
Henry Ford Hospital Medical Journal
No abstract provided.
External Beam Treatment Of Inoperable Non-Small Cell Carcinoma Of The Lung, H. Gunter Seydel
External Beam Treatment Of Inoperable Non-Small Cell Carcinoma Of The Lung, H. Gunter Seydel
Henry Ford Hospital Medical Journal
External beam radiation therapy for unresectable non-small cell carcinoma of the lung has produced significant survival in patients with disease limited to one hemithorax. New approaches to improve the results of radiation treatment of these patients include interstitial implantation, the use of hypoxic cell sensitizers, biologic response modifiers, as well as changes in the technique of radiation therapy. This includes the use of modern computerized tomographic scanning technology for better definition of tumor volume as well as the use of two fractions per day in the treatment of non-small cell carcinoma of the lung. Initial results of these studies are …
Screening Of Patients At High Risk For Cancer, Robert M. O'Bryan
Screening Of Patients At High Risk For Cancer, Robert M. O'Bryan
Henry Ford Hospital Medical Journal
A cancer other than non-melanoma skin cancer will occur in one of every seven persons. Individuals with higher risks for cancer are those with increasing age, hereditary disorders, and a family history of cancer. Lifestyle, especially the use of tobacco and alcohol, diet, and perhaps behavioral patterns influence the risk. Less well understood but clearly pertinent risk factors include environmental and occupational exposures. The risk factors specific for breast cancer include a positive family history of breast cancer, history of mastopathy, age at first pregnancy greater than 35 years, early menarche with late menopause, and history of carcinoma of the …
Family History As A Marker For Increased Risk Of Breast Cancer And Colon Cancer, Robert A. Norum
Family History As A Marker For Increased Risk Of Breast Cancer And Colon Cancer, Robert A. Norum
Henry Ford Hospital Medical Journal
Cancer of the breast and colon are well known to occur with high frequency in families with certain inherited cancer syndromes. These cancers also occur with increased frequency in families which do not have a recognizable genetic cancer syndrome. The fact of familial occurrence can be used to identify people with increased risk of cancer. In high-risk people methods for early detection can be developed which may reduce morbidity and mortality from these cancers, as has been done for certain inherited cancer syndromes.
Elevated Serum Transaminase As A Presenting Clue For Precirrhotic Hemochromatosis, Lester P. Kobylak
Elevated Serum Transaminase As A Presenting Clue For Precirrhotic Hemochromatosis, Lester P. Kobylak
Henry Ford Hospital Medical Journal
For patients in whom unexplained elevations in SGOT and SGPT concentrations are found, determination of the serum iron level is recommended to screen for asymptomatic precirrhotic hemochromatosis. Care must be taken to differentiate between hereditary hemochromatosis and secondary iron accumulation due to liver disease.
Is Normal "Normal"?, Craig C. Foreback
Is Normal "Normal"?, Craig C. Foreback
Henry Ford Hospital Medical Journal
No abstract provided.
The Current Controversies In Surgical Management Of Early Breast Cancer, Angelos A. Kambouris
The Current Controversies In Surgical Management Of Early Breast Cancer, Angelos A. Kambouris
Henry Ford Hospital Medical Journal
No abstract provided.
Polymicrobal Pneumonia In A Corticosteroid-Treated Patient With Chronic Obstructive Lung Disease, John R. Haapaniemi, John Popovich Jr.
Polymicrobal Pneumonia In A Corticosteroid-Treated Patient With Chronic Obstructive Lung Disease, John R. Haapaniemi, John Popovich Jr.
Henry Ford Hospital Medical Journal
The immunosuppressive properties of corticosteroids are well established and cause a depression of pulmonary defense mechanisms. We report the case of a patient treated with short-term corticosteroids for an exacerbation of chronic obstructive lung disease who developed a multiple organism pneumonia.
The Spectrum Of B Cell Neoplasia, Michael J. Deegan
The Spectrum Of B Cell Neoplasia, Michael J. Deegan
Henry Ford Hospital Medical Journal
Recent progress in our understanding of the immune system and the development of new techniques that permit the precise identification of lymphocytes have permitted a reexamination of lymphoid neoplasms. Most of the non-Hodgkin's lymphomas and lymphocytic leukemias have been characterized as T or B cell neoplasms and have been shown to possess features similar to those expressed by normal lymphoid cells at different stages of maturation. The clinical significance and therapeutic implications of these discoveries are now being explored. This paper presents a concise overview of the differentiation of human B lymphocytes, the surface and cytoplasmic markers that permit their …
Peritoneal Lavage Red Blood Cell And White Blood Cell Count: A Prospective Comparison Of Usefulness, Eugene Meyer, James C. Gruenberg
Peritoneal Lavage Red Blood Cell And White Blood Cell Count: A Prospective Comparison Of Usefulness, Eugene Meyer, James C. Gruenberg
Henry Ford Hospital Medical Journal
Prospectively, 637 patients with blunt or penetrating trauma to the lower chest or abdomen had quantitative peritoneal lavage red blood cell (RBC) and white blood cell (WBC) counts as part of their initial diagnostic evaluation. Statistically, the lavage RBC count (error rate: 6.8%) was a superior test to the lavage WBC count (error rate: 9.7%) (chi sq=9.2564, p=0.0024). See Appendix. When the lavage RBC and WBC tests agreed, the predictive value was high: 94% (46/49) when both were positive and 95% (521/549) when both were negative. When the lavage RBC test was positive and the lavage WBC test was negative, …
Pericardial Tamponade In Acute Myeloid Leukemia, R. P. Warrier, K. R. Kini, R. Singh, K. Maeda, I. Barr, F. M. Jara
Pericardial Tamponade In Acute Myeloid Leukemia, R. P. Warrier, K. R. Kini, R. Singh, K. Maeda, I. Barr, F. M. Jara
Henry Ford Hospital Medical Journal
We are reporting a case of acute myeloid leukemia in a child with pericardial effusion and cardiac tamponade, with a review of the literature. Morphologic and cytochemical evidence was used to diagnose acute myeloid leukemia, and radiologic, electrocardiographic, echocardiographic, cytologic, and histologic evidence confirmed the diagnosis of tamponade and pericardial leukemic involvement. Pericardiotomy and pericardial window drainage successfully relieved the tamponade, and conventional chemotherapy was used to induce a remission.
Brief Communication: Streptokinase For Deep Venous Thrombosis, Barry Lesser, Maria A. Sawdyk
Brief Communication: Streptokinase For Deep Venous Thrombosis, Barry Lesser, Maria A. Sawdyk
Henry Ford Hospital Medical Journal
No abstract provided.