Medicine and Health Sciences Commons^™

Comparison Of Risk Factors Of Mortality During The Two Coronavirus Disease 2019 Waves In Delhi, India, Neena Katoch, Ajay K. Gupta, Rachna Gulati, Ketan Garg, Vikas Kumar

Journal of Medicine in Scientific Research

Objective To determine the risk factors of mortality (in terms of age, sex, and comorbidities) among hospitalized patients in an Indian tertiary care hospital during the first and second waves. Patients and methods A retrospective observational study was conducted, where the patients’ mortality data were collected over two coronavirus disease 2019 (COVID-19) periods, and their characteristics were compared. The first phase was from May 2020 to January 2021 and the second wave was from March 2021 to August 2021. Results A mortality rate of 23.84% (874 deaths among 3666 patients) and 1.36% (232 deaths among 17 000 patients) was noted …

Periodontal Regeneration Related To Periodontitis Treated By Garden Cress And Ozone Therapy. (Randomized Clinical &Experimental Study), Zienab S. Farid, Doaa Adel Habba, Gihan Adel Balbola, Noura Mohammed Bakr

Journal of Medicine in Scientific Research

Objective: In this article, garden cress and ozone were evaluated for their potential therapeutic properties of PDL and resorption of alveolar bone in the periodontal tissues based on rats' experimental periodontitis and to assess the clinical effectiveness of local application of garden cress and ozone for treatment and management of periodontitis patients using scaling and root planing. Methodology: Thirty mature Wistar male albino rats. Three groups of rats were formed; periodontitis without treatment, periodontitis with garden cress, and periodontitis plus ozone therapy. The present study also included thirty periodontitis Patients were randomly allocated to one of three groups of ten …

Improvement Of Hair Transplantation In Postcicatracial Alopecia, Maurice Fekry, Ebrahim Awad

Journal of Medicine in Scientific Research

Background Because scarred tissue has less blood flow than normal tissue, fewer hair grafts are taken, and the patient may require many sessions to achieve the acquired density, resulting in a lengthy treatment duration of up to 5 years. The use of platelet-rich plasma (PRP) improves these findings. Patients and methods A prospective randomized-controlled study was conducted on 15 patients with cicatricial alopecia and candidates for follicular unit extraction hair transplantation, with ages between 25 and 60 years. Results Functional and esthetic outcomes were achieved by adding PRP regimen to follicular unit extraction hair transplantation for cases presented to us …

The Rage Gene Crucial Function In The Etiology And Consequences Of Type I Diabetes, Amal A. Mohamed, Mohamed O. Mahmoud, Gamil M. Abdallah, Nada S. Ali, Mona Abdelmotaleb Abdelfatah Hussein, Ibrahim T. Ibrahim

Journal of Medicine in Scientific Research

Type I Diabetes, among the ten greatest causes of mortality worldwide, is estimated to afflict 642 million individuals by 2040. It is an auto-immune illness brought on by an association of environmental and genetic variables. that cause T lymphocytes to destroy insulin-producing β-cells. Its prevalence continues to rise by 3-4% annually worldwide, enhancing the risk of mortality. So, the idea of diabetic kidney disease (DKD) is widely established, and systemic treatment is essential. RAGEs are linked to inflammatory disorders that exist in a variety of TID-related cells; especially T cells. Variations in circulating RAGE concentrations have been linked to a …

Added Value Of Diffusion Weighted Image And Apparent Diffusion Coefficient Mapping In Differentiation Between Bone Marrow Neoplastic Infiltration And Non-Neoplastic Complication In Hematologic Malignancies, Mary Rabea Mahrous, Marwa Romeih, Eman Nasr Said

Journal of Medicine in Scientific Research

BACKGROUND: Hematological malignancies, including lymphomas, leukemia, and multiple myeloma, commonly infiltrate the bone marrow (BM). Commonly observed post-treatment complications that affect BM include osteonecrosis, osteomyelitis, ischemic infarction, pathological fractures, and avascular necrosis. These complications frequently occur secondary to chemotherapy, radiotherapy, and high doses of corticosteroids. Magnetic resonance imaging (MRI) is considered the gold-standard imaging modality for the assessment of BM due to its high contrast resolution without radiation exposure. In hematological malignancies, distinguishing benign from malignant bone marrow changes remains notoriously chellenging. Diffusion-weighted images (DWI) are highly sensitive sequences for assessing the mobility of free water molecules reflecting micro-vascular changes. …

Quantifying T-Regulatory Cells And Their Clinicopathological Relevance In Hodgkin Lymphomas, Nishant Taur, Rashmi Kushwaha, Mili Jain, Richa Ranjan, Akansha Singh

Journal of Medicine in Scientific Research

Introduction: Regulatory T cells (Tregs) constitute a distinct subset of lymphocytes recognized for their ability to dampen immune responses. The significance of Tregs as prognostic indicators in individuals with lymphoma has sparked ongoing debates. Therefore, this study was undertaken to enumerate and correlate the clinicopathological findings of T-regulatory cells in Hodgkin lymphomas. Methodology: This hospital-based prospective observational study included a total of 50 participants. All the enrolled participants were divided into cases (all biopsy/immunophenotypically proven cases of Hodgkin’s Lymphoma; n=30) and controls (healthy individuals; n=20). Clinico-demographic details were recorded and compared. Sample collected from the patients were tagged with specific …

Oral And Dental Health In Systemic Sclerosis: Is It A Window To Other Systemic Affections?, Omnia A Abubakr, Taghreed F M M Mostafa, Mohamed A Hamdy

Journal of Medicine in Scientific Research

Background: Oral and periodontal manifestations are common in systemic sclerosis (SSc) which may result in poor nutritional status and significant morbidity. Better understanding of these manifestations is crucial for better patient outcomes. We aimed to evaluate dental and oral manifestations in patients with SSc in comparison to healthy control and to study the relationship between these findings and systemic sclerosis disease activity index, skin thickness, other systemic affection, as well as the oral health-related quality of life in these patients Patients and Methods: 50 patients with SSc were included in this case-control study (Group A) and 50 apparently healthy controls …

Repair Versus Replacement For Ischemic Mitral Regurgitation In Patients Who Underwent Coronary Artery Bypass Grafting Plus Mitral Valve Surgery, Ramdan Ibrahim Mohammed Ouf, Bassem Ashraf Ahmed Roushdy

Journal of Medicine in Scientific Research

Background: Ischemic mitral regurgitation (IMR) is a serious consequence of coronary artery disease. The optimal management of IMR is controversial. Although practice guidelines advise surgical intervention for patients presenting with a severe form of this condition, they also recognize the limited evidence supporting repair or replacement.

Aim of the study: to analyse and compare the early outcomes of mitral valve repair (MVr) versus mitral valve replacement (MVR) with concomitant CABG in patients with IMR.

Methods: A retrospective comparative study on 100 patients who underwent concomitant CABG for their coronary artery disease (CAD) and a mitral valve surgery for IMR, either …

Effect Of Acupressure On Labor Pain For Women During First Stage Of Normal Labor, Maha Mohamed Mady, Inass Kassem Aly, Eman Hassan Abu-Elmagd, Safaa Gaber Aly

Journal of Medicine in Scientific Research

Background: Acupressure is thought to promote blood flow and the release of neurotransmitters, thereby maintaining the body's regular functions and offering a sense of well-being. Nevertheless, there is limited scientific evidence to substantiate the beneficial impacts of Acupressure in the realm of obstetric healthcare. Purpose of the study: To assess the impact of applying Acupressure at the LI4 acupoint on the pain experienced by women in the initial stage of labor. Research design: An experimental study with a pretest and posttest control group design. A total of 100 women were randomly assigned to two groups. Each group received LI4 Acupressure …

Postoperative Quality Of Life Improvement: Tavi Vs. Mini-Sternotomy Tissue Valve Insertion In Elderly Patients With Significant Aortic Stenosis, Ahmed Shafeek Ali, Mostafa Abd Al Salam Mohamed Ghazi, Mahmoud Maher Abdou Ibrahim, Reham Mohammed Salah Eldin Ahmed

Journal of Medicine in Scientific Research

Background: Postoperative improvements in the quality of life represent a master scale for procedural success, particularly in elderly patients with cardiac conditions. Objectives: To detect positive changes in quality of life for elderly candidates with significant calcific aortic stenosis treated by aortic tissue valve insertion, either through TAVI or mini-sternotomy AVR. Patients and methods: A prospective study was done on 88 patients above 65 years with severe calcific aortic stenosis. They sought treatment at the National Heart Institute in Cairo, Egypt between March 2020 and July 2022. All patients underwent aortic tissue valve replacement. Eight candidates were removed from the …

Predictors Of Residual Vsd After Surgical Versus Transcatheter Closure, Ramdan Ibrahim Mohammed Ouf, Deyaa Ahmed Abdallah Mohamed

Journal of Medicine in Scientific Research

Background: Ventricular septal defect (VSD) repair is a frequently performed cardiac procedure in children, and it is associated with a extremely low likelihood of experiencing post-operative complications. Aim of the study: to identify the incidence of residual shunt across interventricular septum after surgical repair or device closure of isolated VSD or associated with another congenital anomaly. Methods: This is a retrospective study included 60 patients undergoing closure of VSD between January 2021 and January 2023 in National Heart Institute. They were divided into 2 groups: Group I underwent surgical closure (30 patients) and group II underwent transcatheter closure (30 patients). …

Community-Acquired Pneumonia Among Hospitalized Children: Risk Factors, Characteristics, And Outcomes, Marwa Taha, Hanaa Abdel-Wahab

Journal of Medicine in Scientific Research

Background Community-acquired pneumonia (CAP) represents one of the main causes of mortality and morbidity among under-five children worldwide. More than 75% of these fatalities are caused by severe pneumonia. Objectives to identify the potential risk factors associated with severe CAP among under-five children hospitalized with CAP. Patients and Methods This prospective observational study was conducted on children, aged 1 to 59 months, who were admitted with CAP to the Department of Pediatrics, Mataria Teaching Hospital, Egypt. Based on World Health Organization (WHO) guidelines, patients were classified into two groups; CAP and severe CAP. Data including demographic, children's history, clinical assessment, …

Standard Median Sternotomy Versus Minimally Invasive Approach For Atrial Septal Defect Closure In Adults, Ahmed S. Ali, Ahmed G. Abd El Fattah Fahmy, Hatem K. Madkour, Reham M. Salah Eldin Ahmed

Journal of Medicine in Scientific Research

Background

Atrial septal defects (ASDs) in adults and adolescents are not uncommon. Surgical ASD closure through a standard median sternotomy (SMS) has become less attractive approach in favor of minimally invasive techniques, especially in young female patients.

Objective

The aim was to compare early postoperative outcomes of surgically closed secundum ASDs through a SMS approach versus minimally invasive right anterolateral thoracotomy (MIRAT) approach in adults.

Patients and methods

The authors prospectively studied 60 adult patients who had their secundum ASD anomalies surgically closed at National Heart Institute between the period of September 2020 and February 2022. A total of 30 …

Oral Mucosal And Dental Affection In Patients With Systemic Lupus Erythematosus: A Clinical Survey, Omnia A Abubakr, Ali M Youssef, Mohamed A Mohamed, Mohamed A Hamdy

Journal of Medicine in Scientific Research

Background: SLE is a chronic autoimmune disease predominantly affecting young females. Systemic involvement along with variable clinical presentations characterizes SLE. Various oral and dental manifestations have been described in SLE that include oral ulcerations, candida infection, and periodontal disease. We aimed to detect oral mucosal and dental disease in SLE patients and its relation to demographic features, general disease activity, and the extra-articular manifestation. Patients and Methods: 80 patients with SLE were included in this cross-sectional study. Patients were allocated into 2 groups, 40 patients in each group, according to SLE disease control with immunosuppressive medications: group A included patients …

Clinical Findings And Hematological Parameters In Cases Of Acute Lymphoblastic Leukemia With Thrombocytosis At Initial Diagnosis, Anurag Singh, Sanjay Mishra, Tanya Tripathi, Akanksha Singh, Rashmi Kushwaha, S.P. Verma, U.S. Singh

Journal of Medicine in Scientific Research

Background Acute lymphoblastic leukemia (ALL) is a bone marrow and blood neoplasm involving precursor cells, or lymphoblasts, dedicated to B/T-cell lineages. ALL usually presents with bicytopenia/pancytopenia and thrombocytopenia is the most important key parameter. Thrombocytosis has not been a well-described feature of ALL; hence, this study was planned to investigate the incidence of thrombocytosis at initial diagnosis and its correlation with clinicohematological parameters, immunophenotyping, and cytogenetic study. Aim The aim was to investigate the incidence of thrombocytosis in newly diagnosed cases of ALL and its correlation with clinicohematological parameters, immunophenotyping, and cytogenetics. Materials and methods Medical records of all patients …

Forced Expiratory Volume In The 6 S And Forced Expiratory Volume In The 1 S/Forced Expiratory Volume In The 6 S For Early Detection Of Airflow Obstruction, Therese S. Ghatas, Moheb W. Elfaizy

Journal of Medicine in Scientific Research

Introduction

Use of affordable and simple tools for screening chronic obstructive pulmonary disease (COPD) is limited. In recent years, measurement of forced expiratory volume in the 6 s (FEV6) has been researched as a substitute to replace forced vital capacity measurements. This work was performed to analyze the effectiveness of a simplified handheld forced expiratory flowmeter device and to search an optimal cutoff value of FEV1/FEV6 to detect airflow narrowing and limitation.

Patients and methods

This was a cross-section study for screening and finding of active case among undiagnosed patients with COPD using a simple handheld spirometry device, and the …

Mortality Rate Among Preterm Infants With Respiratory Distress Syndrome On Non-Invasive Respiratory Support (Nirs): A ٌRetrospective Multicenter Study, Abeer E.S. Hamed, Alaa A. Rashad, Manar A. El Desouky, Mahmoud H. Dawabah, Mohamed M. A. Shaheen, Heba Allah M. Sherief, Mohamed A. Ibrahim, Sohaila A Abd El-Halim

Journal of Medicine in Scientific Research

Background: Neonatal acute respiratory distress is a common cause for mortality and morbidity in preterm neonates. Non-invasive ventilation is crucial for preterm neonates, nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure. Recently, heated humidified high-flow nasal cannula modes have been revealed as more efficient non-invasive ventilation mode in improving functional residual capacity however, other studies have questioned its efficacy and safety in comparison to other non-invasive ventilation. Many studies have investigated the common predictive factors that are associated with intubation and failure of spontaneous breathing. Consequently, this study aimed at investigating the common factors associated with prolonged …

Molecular Detection Of Entamoeba Histolytica In Diarrheic Fecal Samples From Patients Attending National Hepatology And Tropical Medicine Research Institute, Azza Hasan Abbas, El Shahat Ahmed Elshahat, Heba Mohamed Abdelglil

Journal of Medicine in Scientific Research

Background: Amoebiasis is a worldwide disease caused by Entamoeba histolytica infection. The true prevalence is unknown due to the difficulty in distinguishing Entamoeba histolytica from non-pathogenic amoebas especially when microscopic diagnosis is performed, to overcome microscopy misidentification. Polymerase Chain Reaction (PCR) assay is necessary as a highly sensitive and specific technique. Objective: To determine the value of Real-Time PCR (RT.PCR) in the diagnosis of Entamoeba histolytica in the stool samples of diarrheic patients attending NHTMI versus microscopy, copro- antigen, and serum antibodies detection techniques. Subjects and Methods: A cross-sectional study was conducted on 150 diarrheic patients. Their stool samples were …

The Relation Between Heart Rate Response During Exercise And Angiographic Severity In Patients With Chronic Coronary Syndrome, Emmanuel Louka

Journal of Medicine in Scientific Research

Introduction Ellestad and colleagues, in 1975, reached to the conclusion that impaired heart rate response to exercise carries a similar risk for future coronary events such as ischemic ‘ST’ segment changes. Mc Neer and colleagues went beyond these observations to include a survival benefit in patients who achieve a higher peak heart rate (PHR), a more advanced level of exercise, and have a normal exercise electrocardiogram. Aim The aim of this work is to clarify the relation between the chronotropic response to exercise and the severity of coronary artery disease in patients with chronic coronary syndrome. Patients and methods The …

Dental And Oral Manifestations Of Rheumatoid Arthritis: Is It Related To General Disease Activity?, Omnia A. Abubakr, Ali M Youssef, Mohamed A Mohamed, Mohamed A Hamdy

Journal of Medicine in Scientific Research

Background: RA is a chronic immune-mediated systemic disorder; its pathogenesis is complex. Genetic, environmental, hormonal, and lifestyle are the main risk factors. The correlation between oral health and RA is rising. Oral manifestations in RA include temporomandibular joint disorder, secondary Sjögren’s syndrome, xerostomia, and periodontal disease. Previous studies suggest a bidirectional relationship between RA and periodontal diseases. This study aims to detect oral mucosal and dental disease in RA patients and its relation to demographic features, disease activity, and extra-articular manifestation. Patients and Methods: This cross-sectional study included 150 patients with RA allocated into two groups, 75 patients in each …

Comparative Study Between Intravenous Anesthesia (Propofol) And Inhalational Anesthesia (Sevoflurane) On The Cytokine’S Response To Abdominal Operation, Ashraf A.H. Mahmoud Soliman, Maisa M. Abdel Khalik, Wael A.E. El Hakeem, Raghad S. Abdellatif

Journal of Medicine in Scientific Research

Introduction These days, the need for more information and familiarity with the inflammatory response to different anesthetic drugs increase. Not only some patients suffering from immune reactions against some anesthetic drugs, but all surgical patients are liable to decrease in immunity postoperatively. This may increase the postoperative morbidity and mortality, affects healing, and spread of tumors postoperatively. This decrease in immunity is due to surgery trauma causing imbalance in cytokine response. Patients and methods This article was written on 40 patients, and patients were randomly classified into four equal classes. Class A: inhalational anesthesia on major operation. Class B: intravenous …

Endovascular Management Of Vein Of Galen Aneurysmal Malformations: Case Series And Review Of The Literature, Mohammed A. El-Din Habiba, Sameh M. Saleh

Journal of Medicine in Scientific Research

Background Neonates with vein of Galen aneurysmal malformations (VGAMs) who present with heart failure have a high rate of morbidity and mortality, while those who present later in childhood have considerably better outcomes. Aim To determine the factors that have the greatest predictive value in predicting long-term results in children with VGAM. Patients and methods Between June 2015 and June 2020, 15 patients (seven infants, eight children) were diagnosed with symptomatic VGAMs, four of whom were suffering from intractable high-output heart failure and received initial endovascular treatment. All of them were treated by endovascular procedures. Staged transarterial route was the …

Different Modalities Of Tongue Tie Management, Wesam Ibrahem Homouda, Esayed Hussien Elmokadem, Mohamed Amr Hamdy Salem

Journal of Medicine in Scientific Research

Background: Tongue-tie or ‘ankyloglossia’ is a congenital anomaly characterized by presence of an abnormally tight lingual frenulum - a string like membrane – that attaches the tongue to the floor of the mouth. It affects the movement of the tongue. For symptomatizing ankyloglossia surgical treatment with different surgical techniques such as (Frenotomy, frenectomy/frenulectomy, and frenuloplasty) is the treatment of choice that gives satisfactory results. Objectives: We built our study to compare between different surgical techniques used for management of ankyloglossia. Patient and method: in our study 60 patients were included 33 were female and 27 were male with age ranging …

A Case Of Congenital Diaphragmatic Hernia Presenting In The Adult As Gastric Volvulus, Sajal Gupta, Ismail Khan, Indu B. Dubey, Mayank Verma

Journal of Medicine in Scientific Research

We report a case of an adult patient who was referred to the surgical emergency for the evaluation of acute abdominal pain and vomiting. Radiograph chest showed a left-sided cavity, which was misleading to lung pathology. A suspicion of gastric volvulus was kept in mind on seeing the stomach in the radiograph. Computed tomography confirmed the diagnosis of diaphragmatic hernia. The insertion of the Ryle’s tube corrected the gastric volvulus. An immediate laparotomy was done for the closure of the diaphragmatic gap and reduction of the herniated contents. The patient responded well and was discharged in a week.

Complete Dorsal Pancreatic Agenesis: A Case Report, Ritish Gupta, Ashima Mittal, Bhavna Arora, Riya Aggarwal

Journal of Medicine in Scientific Research

Complete agenesis of the dorsal pancreas (ADP), an extremely rare congenital anomaly, is caused as ‘the dorsal pancreatic bud fails in developing the body and tail of the pancreas at the time of embryological development.’ There are nearly 100 cases of dorsal pancreatic agenesis till date. Most of the individuals with ADP are without symptoms; however, few may present with clinical manifestations like pancreatitis, epigastric pain, hyperglycemia, and diabetes mellitus. This is a case report of a 19-year-old female with ADP, who was diagnosed incidentally while undergoing radiological assessment for abdominal pain in left hypochondrium. As complete ADP is very …

Role Of High-Resolution Ultrasonography And Electromyography In The Evaluation Of Patients With Flat Foot, Mai M. Kamel, Ahmed Abdelrahman Elatreby, Amr M. Gamil, Gamal Salah Eldin Elmorsy

Journal of Medicine in Scientific Research

Objective: The present work aimed to assess the abductor hallucis (AH) muscle changes using sonographic and electrophysiologic studies in flatfoot patients. Patients and methods: This study included 60 patients with flatfoot deformity (group I) and 20 age and sex-matched healthy individuals as a control group (group II). The patients were subjected to full history taking, clinical assessment, foot x-ray examination, high-resolution ultrasound, and surface electromyography (EMG) of AH muscle. Using a plain x-ray, Meary's angle was measured, and severity grading was categorized for the patient group. Results: The AH ultrasonography revealed a significant difference between patient and control groups regarding …

Prevalence Of Upper Limb Musculoskeletal Abnormalities In Type 2 Diabetic Patients And Its Relation To Glycemic Control And Associated Factors, Eslam Elsayed Ali Shohda, Amal Emam El-Maghraby, Hadeer Khaled Youssef Elhamid

Journal of Medicine in Scientific Research

Aim of the study: to investigate the prevalence of upper limb musculoskeletal abnormalities and their correlations to glycemic control and associated factors. Methods: A cross-sectional study was conducted at diabetes unit and internal medicine outpatient clinic at Al-ahrar teaching hospital, Zagazig, Egypt. 200 type 2 diabetic patient (T2DM) and 200 non-diabetic control patients of ages > 18 years were enrolled. Rheumatological diseases were excluded. Studied upper limb musculoskeletal abnormalities were Limited joint mobility (LJM), Dupuytren’s contracture (DC), Trigger finger (TF), De Quervain’s tenosynovitis (DQT), Lateral epicondylitis (LE), Medial epicondylitis (ME), Rotator’s cuff tendinitis (RCT) and Carpel tunnel syndrome susceptibility diagnosed by …

Glyceryl Trinitrate Cream Versus Lateral Sphincterotomy In Management Of Chronic Anal Fissure: A Prospective Randomized Comparative Study, Naser T. Elshamy

Journal of Medicine in Scientific Research

Objective The aim is to compare complications and long-term outcome of two treatment modalities of chronic anal fissure: chemical sphincterotomy by glyceryl trinitrate (GTN) cream and lateral internal sphincterotomy. Background Treatment of chronic anal fissure is achieved by the reduction in the tone of the internal anal sphincter either chemically or surgically. Patients and methods In the period from November 2013 to October 2015, all patients who were admitted to the Department of General Surgery in Shebin Elkom Teaching Hospital complaining of chronic anal fissure were included in the study. According to inclusion and exclusion criteria, patients were selected and …

Saphenous Vein Harvesting With Endoscopy Versus No-Touch Technique: Short-Term Results, Tamer El Bannaa, Mohamed M. Mohamed, Ahmed Zayed, Yasser A. Sadek

Journal of Medicine in Scientific Research

Objective ‘No-touch’ (NT) saphenous vein harvesting maintains vasa vasorum, resulting in less medial ischemic affection, which leads to improved short-term and long-term patency. However, it may also be associated with a higher rate of wound complications. Endovascular vein harvesting (EVH) has a low rate of wound complications but also a tendency toward a lower patency rate. The aim was to compare wound complications and short-term symptomatic relief, which could be an indication of functioning grafts. Patients and methods During a 2-year period (2018–2019), in a nonrandomized prospective study, we monitored patients after coronary artery bypass graft for recurrence of ischemic …

Assessment Of Carotid Intima-Media Thickness And Its Relation To Cardiovascular Risk Factors In Obese Children, Faten A.A. Fathi, Somaya M. Abd El Ghany, Ahmed A.H. Taha, Gihan F.A. Hassan, Eman Fouad

Journal of Medicine in Scientific Research

Background Childhood obesity is one of the most critical public health problems today. This study aims to assess the relation between carotid intima-media thickness (CIMT) and cardiovascular risk factors in obese children. Patients and methods This is a case–control study conducted on 80 Egyptian children aged 6–18 years; 40 children with simple obesity as defined by WHO (2011) and 40 healthy children age matched and sex matched were taken as a control group. Cases were selected from the National Nutritional Institute randomly from December 2017 to March 2018. All patients and control groups were subjected to the following: full history …