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F-2-Isoprostanes As Novel Biomarkers For Type 2 Diabetes: A Review, Ikram Shah Ismail
F-2-Isoprostanes As Novel Biomarkers For Type 2 Diabetes: A Review, Ikram Shah Ismail
Ikram Shah Ismail
Oxidative stress (OS) has been implicated as one of the major underlying mechanisms behind many acute and chronic diseases. However, the measurement of free radicals or their end products is complicated. Isoprostanes, derived from the non-enzymatic peroxidation of arachidonic acid are now considered to be reliable biomarkers of oxidant stress in the human body. Isoprostanes are involved in many of the human diseases such as type 2 diabetes. In type 2 diabetes elevated levels of F-2-Isoprostanes (F-2-IsoPs) have been observed. The measurement of bioactive F-2-IsoPs levels offers a unique noninvasive analytical tool to study the role of free radicals in …