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Prehospital Antibiotics Improve Morbidity And Mortality Of Emergency Medical Service Patients With Sepsis, Thomas Martel, Monica N. Melmer, Samuel M. Leaman, Nicole Kassen, Seth Kozlowski, Jonathan Pangia, Scott Gutovitz, Dietrich Jehle
Prehospital Antibiotics Improve Morbidity And Mortality Of Emergency Medical Service Patients With Sepsis, Thomas Martel, Monica N. Melmer, Samuel M. Leaman, Nicole Kassen, Seth Kozlowski, Jonathan Pangia, Scott Gutovitz, Dietrich Jehle
HCA Healthcare Journal of Medicine
Background: Severe sepsis is a major cause of mortality in patients evaluated in the Emergency Department (ED). Early initiation of antibiotic therapy and IV fluids in the ED is associated with improved outcomes. We investigated whether early administration of antibiotics in the prehospital setting improves outcomes in these patients with sepsis.
Methods: This is a retrospective study comparing outcomes of patients meeting sepsis criteria in the field by EMS, who were treated with IV fluids and antibiotics. Their outcomes were compared with controls where fluids were administered prehospital and antibiotics were initiated in the ED. We compared morbidity and mortality …