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Impact Of Radiation Therapy Fraction Size On Local Control Of Early Glottic Carcinoma, Edward Yu, George Shenouda, Marie Beaudet, Martin Black Jan 1997

Impact Of Radiation Therapy Fraction Size On Local Control Of Early Glottic Carcinoma, Edward Yu, George Shenouda, Marie Beaudet, Martin Black

Edward Yu

Purpose: Different radiotherapy fractionation schedules were used over a 10-year period to treat patients with early squamous cell carcinoma of the vocal cords at McGill University. A retrospective analysis was performed to study the effect of fraction size on local control in this group of patients. Methods and materials: A total of 126 previously untreated patients with T1 invasive squamous cell carcinoma of the true vocal cords were irradiated between January 1978 and December 1988 in the Department of Radiation Oncology at McGill University. All patients received megavoltage irradiation, 94 patients received daily fractions > 2 Gy (64 patients received 50 …


Vitamin D And Parotid Gland Function In The Rat, C. Peterfy, A. Tenenhouse, E. Yu Mar 1988

Vitamin D And Parotid Gland Function In The Rat, C. Peterfy, A. Tenenhouse, E. Yu

Edward Yu

1. We previously reported that parotid gland secretion is decreased in rats deprived of vitamin D (Glijer, Peterfy & Tenenhouse, 1985). In the present study we examine whether this effect is a direct result of the absence of vitamin D or due to the secondary systemic effects of vitamin D deficiency. 2. Offspring of rats maintained on a calcium-supplemented (1.2%), vitamin-D-deficient diet were weaned onto the same diet and examined after 8 weeks. Using this method it was possible to maintain serum calcium and parathyroid hormone concentrations within normal limits. Serum 25-hydroxyvitamin D (25(OH)D3) was not detectable, but 1,25-dihydroxyvitamin D …