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Medicine and Health Sciences Commons

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Medical Sciences

TÜBİTAK

Oxidative stress

2014

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Full-Text Articles in Medicine and Health Sciences

Effects Of Short-Term Hyperglycemia On The Vasoconstriction Of The Aorta, Soner Dönmez, Osman Gökalp, Mustafa Doğan, Hüseyi̇n Vural, Barbaros Yi̇ği̇t Jan 2014

Effects Of Short-Term Hyperglycemia On The Vasoconstriction Of The Aorta, Soner Dönmez, Osman Gökalp, Mustafa Doğan, Hüseyi̇n Vural, Barbaros Yi̇ği̇t

Turkish Journal of Medical Sciences

To investigate vasoconstrictor responses of healthy blood vessels to short-term hyperglycemic conditions such as postprandial hyperglycemia, gestational diabetes mellitus, and steroid-induced diabetes. Materials and methods: Female Wistar rat aorta rings were incubated in normal (11 mM) and high (22 mM and 44 mM) glucose concentrations for 4 h. Responses of vasoconstriction were measured in reaction to serotonin (10-5 M), phenylephrine (10-6 M), and KCl (60 mM) compared to the ambient condition, including different glucose concentrations. Results: While the responses of vasoconstriction to KCl were increased in the presence of Krebs' solution with high glucose, no statistically significant changes were observed …


Association Analyses Of Oxidative Stress, Aerobic Capacity, Daily Physical Activity, And Body Composition Parameters In Patients With Mild To Moderate Copd, Abdurrahman Genç, Kağan Üçok, Ümi̇t Şener, Tülay Koyuncu, Olcay Akar, Sefa Çeli̇k, Mehmet Ünlü Jan 2014

Association Analyses Of Oxidative Stress, Aerobic Capacity, Daily Physical Activity, And Body Composition Parameters In Patients With Mild To Moderate Copd, Abdurrahman Genç, Kağan Üçok, Ümi̇t Şener, Tülay Koyuncu, Olcay Akar, Sefa Çeli̇k, Mehmet Ünlü

Turkish Journal of Medical Sciences

To investigate total oxidant and antioxidant status, maximal aerobic capacity, daily physical activity, pulmonary functions, and body composition changes, as well as the associations among these parameters, in patients with mild to moderate chronic obstructive pulmonary disease (COPD) versus healthy controls. Materials and methods: The study included 30 male patients newly diagnosed with COPD and 30 body mass index-matched, nonsmoker male controls. Maximal aerobic capacity, daily physical activity, total oxidant and antioxidant status, pulmonary function tests, body composition, and anthropometric parameters were measured. Results: Maximal aerobic capacity and total antioxidant values were lower in patients with COPD compared to the …


Effects Of Ozone Therapy And Taurine On Ischemia/Reperfusion-Induced Testicular Injury In A Rat Testicular Torsion Model, Tolga Reşat Aydos, Mehmet Murad Başar, Oğuz Kul, Hasan Tarik Atmaca, Tuba Uzunali̇oğlu, Üçler Kisa, Oğuzhan Eki̇n Efe Jan 2014

Effects Of Ozone Therapy And Taurine On Ischemia/Reperfusion-Induced Testicular Injury In A Rat Testicular Torsion Model, Tolga Reşat Aydos, Mehmet Murad Başar, Oğuz Kul, Hasan Tarik Atmaca, Tuba Uzunali̇oğlu, Üçler Kisa, Oğuzhan Eki̇n Efe

Turkish Journal of Medical Sciences

To investigate the effect of ozone and/or taurine treatment comparatively on testicular damage due to ischemia/reperfusion (I/R) injury in an experimental torsion model in rats. Materials and methods: Adult Wistar rats with and without torsion/detorsion were used. In order to monitor the effect of ozone and/or taurine treatment on testicular damage due to I/R injury, following histopathological investigation apoptotic indexes were scored by TUNEL method. Moreover, tumor necrosis factor receptor 1 (TNFR1), caspase 3, caspase 8, endothelial nitric oxide synthase (eNOS), tumor necrosis factor alpha (TNF\alpha), and cytochrome C immunostainings were performed and the levels of malondialdehyde, glutathione peroxidase, superoxide …