Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 17 of 17
Full-Text Articles in Medicine and Health Sciences
Comprehensive Comparison Of Clinicoradiological, Laboratory, And Prognostic Factors Of Community-Acquired Pneumonia In Diabetic And Nondiabetic Hospitalized Patients, Seyyed Hamid Hashemi, Fatemeh Saki, Shiva Borzouei, Rashed Bawand, Alireza Soltanian
Comprehensive Comparison Of Clinicoradiological, Laboratory, And Prognostic Factors Of Community-Acquired Pneumonia In Diabetic And Nondiabetic Hospitalized Patients, Seyyed Hamid Hashemi, Fatemeh Saki, Shiva Borzouei, Rashed Bawand, Alireza Soltanian
Turkish Journal of Medical Sciences
Background/aim: Community-acquired pneumonia (CAP) is one of the leading infectious causes of mortality, and diabetes mellitus is a globally prevalent disease. Consequently, the cooccurrence of these two disorders can be common and create challenging medical conditions. Therefore, it was aimed to compare the various aspects of CAP in diabetic and nondiabetic patients, in order to have a comprehensive and comparative picture of the differences. Materials and methods: In this cross-sectional study, CAP patients with and without diabetes were assessed for clinicoradiological signs, laboratory features, disease severity, and pneumonia outcomes. Results: Analyzed herein were 172 CAP patients (77 had diabetes and …
The Diagnostic Profile And Clinical Course Of Patients With Rheumatic Diseases In The Medical Intensive Care Unit, Kani̇ye Aydin, İpek Türk
The Diagnostic Profile And Clinical Course Of Patients With Rheumatic Diseases In The Medical Intensive Care Unit, Kani̇ye Aydin, İpek Türk
Turkish Journal of Medical Sciences
Background/aim: Immunosuppressive and immunomodulatory treatments developed in recent years as a result of a better understanding of the pathophysiology of systemic rheumatic diseases (SRDs) improve the prognosis. Despite medical advances, individuals with SRDs at any stage may require intensive care and have a high mortality rate. The aim of this study was to investigate the demographic and clinical characteristics of patients with rheumatic diseases admitted to the intensive care unit (ICU), and the factors associated with the risk of mortality. Materials and methods: This was a retrospective, cross-sectional study that included patients with rheumatic diseases in the medical ICU. Factors …
Identification Of Subclinical Iron Deficiency Using New Erythrocytes, Leukocytes, And Reticulocytes Parameters During Nonsevere Acute Infection In Pediatric Outpatients, Nazmi̇ Mutlu Karakaş, Serap Ki̇rki̇z Kayali, Zühre Kaya
Identification Of Subclinical Iron Deficiency Using New Erythrocytes, Leukocytes, And Reticulocytes Parameters During Nonsevere Acute Infection In Pediatric Outpatients, Nazmi̇ Mutlu Karakaş, Serap Ki̇rki̇z Kayali, Zühre Kaya
Turkish Journal of Medical Sciences
Background/aim: This study aims to investigate the diagnostic utility of new erythrocytes, leukocytes, and reticulocytes parameters for the identification of subclinical iron deficiency (ID) in children under 6 years with nonsevere acute infection in pediatric outpatients. Materials and methods: The study included 102 children with acute infections and 31 true ID. Traditional and new hematology parameters were measured in a Sysmex-XN® , along with C-reactive protein level, and iron parameters. Participants? ID were categorized as: the ferritin < 100 ng/mL, transferrin saturation < 20% was defined as ?subclinical or functional ID (FID) in Group 1?; ferritin < 30 ng/mL, transferrin saturation < 20%, as ?absolute-ID (AID)? in Group 2; ferritin < 12 ng/mL without anemia and infection, as ?true ID? in Group 3. Results: The frequencies of FID and AID among the 102 children with acute infection were 24% and 76%, respectively. Compared with the Group 2 patients, Group 1 had a significantly higher mean percentage of hypochromic erythrocytes (Hypo-He), and significantly lower levels of hemoglobin (Hb) and Hb content of reticulocytes (RET-He) (p < 0.05 for all). Compared with Group 2 and Group 3 patients, Group 1 had a significantly higher mean percentage of immature reticulocyte fraction (IRF) and immature granulocyte (IG) values (p < 0.05 for all). The RET-He, IRF%, Hypo-He%, and IG% cut-off values for predicting FID during infection were 27.0 pg, 10.6%, 2.5%, and 0.35% respectively. Conclusion: The RET-He, Hypo-He, IRF, and IG may be useful parameters for identifying subclinical ID in small children with nonsevere acute infection in pediatric outpatients.
Current Infection Prevention And Control Strategies Of Covid-19 In Hospitals, Gamze Kalin Ünüvar, Mehmet Doğanay, Emi̇ne Alp
Current Infection Prevention And Control Strategies Of Covid-19 In Hospitals, Gamze Kalin Ünüvar, Mehmet Doğanay, Emi̇ne Alp
Turkish Journal of Medical Sciences
Background/aim: Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has been appeared first in China since December 2019. Transmission of SARS-CoV-2 occurs primarily with droplets through coughing and sneezing and also occurs through inhalation of aerosolized secretions, which travel, remain suspended in the air longer. Materials and methods: Since early stages of the outbreak, COVID-19 cases have been described in healthcare workers (HCWs). However, in the early stages, the disease may be asymptomatic. This may lead to incorrect diagnosis or delayed diagnosis and may lead to the nosocomial spread of the virus. One of the …
Peripheral Arterial Disease Increases The Risk Of Multidrug-Resistant Bacteria Andamputation In Diabetic Foot Infections, Pinar Aysert Yildiz, Tuğba Özdi̇l, Murat Di̇zbay, Özlem Güzel Tunçcan, Kenan Hizel
Peripheral Arterial Disease Increases The Risk Of Multidrug-Resistant Bacteria Andamputation In Diabetic Foot Infections, Pinar Aysert Yildiz, Tuğba Özdi̇l, Murat Di̇zbay, Özlem Güzel Tunçcan, Kenan Hizel
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the microbiological profile and resistance rates of diabetic foot infections (DFIs) and to determine the effect of peripheral arterial disease (PAD) on the microbiology, clinical condition, and treatment outcomes. Materials and methods: Characteristics, laboratory and imaging data, and the treatment modalities of patients admitted to our hospital with a diagnosis of DFI (PEDIS classification 3-4) during 2005-2016 were analyzed according to the presence of PAD. Results: Of 112 patients who were included in this study, 86 (76.8%) had PAD. Patients with PAD were older and had higher amputation rates (P < 0.05). A microbiological profile of patients revealed a predominance of gram-positive bacteria (57.1%). Staphylococcus aureus and Streptococcus spp. were the most frequently encountered bacteria. Incidence of Pseudomonas spp. infection was higher in the PAD group (P < 0.05). Of all patients, 24.1% had multidrug-resistant (MDR) microorganisms in their wound cultures. Presence of MDR bacteria in patients with PAD was 4.9-fold higher than that in patients without PAD (P < 0.05). Conclusion: This retrospective study indicates that PAD has a significant role, especially in elderly patients with DFIs. Patients should be promptly evaluated and treated for PAD to prevent infections with resistant microorganisms and limb loss.
Evaluation Of Major And Minor Lower Extremity Amputation In Diabetic Foot Patients, Firat Ozan, Kaan Gürbüz, İlhami̇ Çeli̇k, Zehra Beştepe Dursun, Erdal Uzun
Evaluation Of Major And Minor Lower Extremity Amputation In Diabetic Foot Patients, Firat Ozan, Kaan Gürbüz, İlhami̇ Çeli̇k, Zehra Beştepe Dursun, Erdal Uzun
Turkish Journal of Medical Sciences
Background/aim: We evaluated the existing risk factors with clinical results in patients who underwent major and minor amputation of the lower extremity as a result of diabetic foot ulcers (DFUs). Materials and methods: We retrospectively studied 107 patients who had undergone lower extremity amputation. The patients were divided into minor (Group 1, n = 75) and major (Group 2, n = 32) amputation groups. On clinical evaluation, the type of surgery performed, smoking history, comorbidities, duration of diabetes mellitus (DM) diagnosis, duration of DFU presence, peripheral neuropathy, peripheral arterial disease, results of deep tissue culture, length of hospitalization, and blood …
The Prevalence Of Infectious Agents In Patients With Systemic Sclerosis, Hüseyi̇n Bi̇lgi̇n, Hi̇lal Kocabaş, Recep Keşli̇
The Prevalence Of Infectious Agents In Patients With Systemic Sclerosis, Hüseyi̇n Bi̇lgi̇n, Hi̇lal Kocabaş, Recep Keşli̇
Turkish Journal of Medical Sciences
Background/aim: Systemic sclerosis (SSc) is an autoimmune disease characterized by microvascular injury, excessive extracellular matrix deposition, and fibrosis in the skin and internal organs. Bacterial and viral infectious agents have been suspected to be contributing factors in the development and progression of the pathologic features of SSc. Materials and methods: In this study, 30 SSc patients who were admitted to the rheumatology unit of the Konya Training and Research Hospital and 30 healthy controls were included. The presence of 9 different antibodies (IgM and IgG) against Helicobacter pylori, cytomegalovirus (CMV), Epstein-Barr virus (EBV), and parvovirus B19 were investigated in sera …
Management Of Community-Acquired Acute Bacterial Cystitis In Turkey, Ömer Coşkun, Hakan Erdem, Ali̇ Avci
Management Of Community-Acquired Acute Bacterial Cystitis In Turkey, Ömer Coşkun, Hakan Erdem, Ali̇ Avci
Turkish Journal of Medical Sciences
Community acquired acute bacterial cystitis (CA-ABC) is one of the most common infectious presentations in the community. This paper aims to provide a rational approach in the management of CA-ABC based on local Turkish data. Materials and methods: The publications evaluating the microbiological data obtained from CA-ABC cases were searched in both Turkish and international databases. Results: Fosfomycin and nitrofurantain appear to be baseline antibiotics while the empirical use of trimethoprim sulfamethoxazole, amoxicillin clavulanate, and first and second generation cephalosporins seems to be unreliable in Turkey. Moreover, quinolones seem to be at the edge with resistance rates up to 20%. …
Evaluation Of The Tick Bites In A Crimean-Congo Haemorrhagic Fever (Cchf) Endemic Area In Turkey, Serpi̇l Erol, Ahmet Yeni̇solak, Göknur Yapar Toros, Ayşe Albayrak
Evaluation Of The Tick Bites In A Crimean-Congo Haemorrhagic Fever (Cchf) Endemic Area In Turkey, Serpi̇l Erol, Ahmet Yeni̇solak, Göknur Yapar Toros, Ayşe Albayrak
Turkish Journal of Medical Sciences
After the first description of a CCHF outbreak in Turkey, tick bites became an increasing cause of visits to health-care facilities. In this study, we evaluated tick bites in a CCHF endemic region. Materials and methods: The study included cases of tick bites that were referred to 2 hospitals in Erzurum between June and October 2008. All cases were followed-up for 10 days for the results of CCHF. Results: During the study period, 161 patients were admitted for a tick bite. The majority (56.3%) were farmers and housewives. Children ≤ 13 years of age were bitten mostly on the head …
The Need For Antibiotic Prophylaxis Before Urodynamic Studies, Adnan Şi̇mşi̇r, Rashad Mammadov, Fuat Kizilay, Mehmet Ceyhun Özyurt
The Need For Antibiotic Prophylaxis Before Urodynamic Studies, Adnan Şi̇mşi̇r, Rashad Mammadov, Fuat Kizilay, Mehmet Ceyhun Özyurt
Turkish Journal of Medical Sciences
The use of antibiotic prophylaxis before urodynamic studies (US) is not recommended routinely. We investigated the factors that would enable us to predict bacteriuria that is likely to develop after US, and that make us consider the need for prophylaxis. Materials and methods: One hundred and four patients who would undergo US with a suspicion of lower urinary tract dysfunction were enrolled in the present study and followed up prospectively. The relationship between bacteriuria and several parameters, such as gender, age, body mass index, glomerular filtration rates, systemic diseases, urinary flow rates, residual urine volume, the type of process performed, …
Viral Etiology And Symptoms Of Acute Upper Respiratory Tract Infections In Children, Emi̇n Ünüvar, İsmai̇l Yildiz, Ayşe Kiliç, Seyhan Selvi̇ Aslan, Bülent Çakal, Sadik Toprak, Seli̇m Badur, Fatma Oğuz, Müjgan Sidal
Viral Etiology And Symptoms Of Acute Upper Respiratory Tract Infections In Children, Emi̇n Ünüvar, İsmai̇l Yildiz, Ayşe Kiliç, Seyhan Selvi̇ Aslan, Bülent Çakal, Sadik Toprak, Seli̇m Badur, Fatma Oğuz, Müjgan Sidal
Turkish Journal of Medical Sciences
Aims: To determine viral causes of acute upper respiratory tract infections and clinical findings in children living in Istanbul, Turkey. Materials and Methods: This prospective study was carried out in 234 outpatient children (age range: 1-180 months) with acute upper respiratory tract infections, seen in the outpatient clinic at Istanbul Medical School Children´s Hospital. After clinical findings were recorded, nasal swab specimens were taken. In 201 specimens collected, influenza-A and -B, adenovirus, respiratory syncytial virus, and parainfluenza viruses were studied using direct fluorescence antibody, polymerase chain reaction (PCR), and cell culture techniques. Results: Rate of virus isolation was 29.8% (60/201). …
Spectrum Of Clinical Infectious Diseases In Hospitalized Elderly Patients In The Southeast Of Iran, Batool Sharifi-Mood, Maliheh Metanat
Spectrum Of Clinical Infectious Diseases In Hospitalized Elderly Patients In The Southeast Of Iran, Batool Sharifi-Mood, Maliheh Metanat
Turkish Journal of Medical Sciences
Aim: The elderly have defective host defenses that compromise their ability to ward off infectious agents; factors influencing immunocompetence include impaired host defenses such as diminished cell-mediated immunity, changes in chronic diseases, medications, malnutrition and functional impairments. This study was conducted in order to determine the pattern of clinical infectious diseases in a series of hospitalized elderly patients. Materials and Methods: In this cross-sectional study, all elderly patients who were admitted to our hospital in Zahedan (Southeast Iran) between 2001 and 2006 were evaluated. We retrospectively reviewed the 1278 patients for diagnostic studies, risk factors, treatment options and morbidity and …
Comparison Of The Antibacterial Effects Of Two Local Anesthetics: Lidocaine And Articaine, Kadi̇r Kaya, Seyyal Rota, Bora Doğan, Gi̇zem Kökten, Berri̇n Günaydin, Gülendam Bozdayi
Comparison Of The Antibacterial Effects Of Two Local Anesthetics: Lidocaine And Articaine, Kadi̇r Kaya, Seyyal Rota, Bora Doğan, Gi̇zem Kökten, Berri̇n Günaydin, Gülendam Bozdayi
Turkish Journal of Medical Sciences
Aim: The antibacterial effect of lidocaine has been studied widely, but the effect of articaine has not yet been evaluated. We aimed to investigate whether commercially available articaine possesses bactericidal or bacteriostatic effect in comparison with lidocaine in a prospective laboratory setting. Materials and Methods: The antibacterial effects of articaine and lidocaine were studied on Pseudomonas aeruginosa ATCC27853, Staphylococcus aureus ATCC25923, Escherichia coli ATCC35218, and Proteus mirabilis ATCC7002 strains and a patient isolate of Serratia marcescens. For this study, 2% lidocaine HCl and articaine HCl were diluted to 10, 5, 2.5, 1.25, 0.625, 0.312, 0.156, and 0.078 mg ml^{-1} concentrations …
Gunshot Wounds And Late Infection, Orhan Yildiz, Emi̇ne Alp, Serap Şi̇mşek, Ahmet Selçuklu, Mehmet Doğanay
Gunshot Wounds And Late Infection, Orhan Yildiz, Emi̇ne Alp, Serap Şi̇mşek, Ahmet Selçuklu, Mehmet Doğanay
Turkish Journal of Medical Sciences
LDIZ^1, Emine ALP^1, Serap ŞİMŞEK^1, Ahmet SELÇUKLU^2, Mehmet DOĞANAY^2 ^1Department of Infectious Diseases, Faculty of Medicine, Erciyes University, Kayseri - Turkey ^2Department of Neurosurgery, Faculty of Medicine, Erciyes University, Kayseri - Turkey
Radioimmune Imaging Of Diabetic Foot Infection -Tc-99m-Labelled Antigranulocyte Antibody In Combination With Tc-99m-Methylene Diphosphonate Bone Scintigraphy, Hripsime Artjun Bohchelian, Anelia Dimitrova Klisarova, Lidia Asenova Koeva
Radioimmune Imaging Of Diabetic Foot Infection -Tc-99m-Labelled Antigranulocyte Antibody In Combination With Tc-99m-Methylene Diphosphonate Bone Scintigraphy, Hripsime Artjun Bohchelian, Anelia Dimitrova Klisarova, Lidia Asenova Koeva
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the clinical efficacy of immunoscintigraphy with Tc-99m-labelled antigranulocyte antibody in combination with Tc-99m-methylene-diphosphonate (MDP) bone scanning in diabetic foot infection. The study group comprised 42 Type 2 diabetics with foot infection. Pre- and postprandial blood glucose level, HbA1c, urinary glucose, microalbuminuria, total cholesterol, LDL-cholesterol, HDL-cholesterol, and bacteriological cultures were analyzed. Investigation of transcutaneous oxygen tension, vibration sensation, electromyo-graphy, and Doppler ankle/brachial systolic blood pressure index was carried out. Radiographs centered on the feet were performed. All patients underwent bone scintigraphy with 370 MBq Tc-99m-MDP three hours after injection in 3 projections. Radioimmune …
The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay
The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay
Turkish Journal of Medical Sciences
Corticosteroids, widely used in the treatment of collagen tissue diseases, increase the number of neutrophils and decrease the total numbers of lymphocytes, monocytes, eosinophils and basophils. In addition, corticosteroids alter important functional activities of both lymphocytes and monocytes. They suppress the bactericidial activities of phagocytes. In this manner, the resistance to infections is reduced. Cytotoxic drugs can have profound effects on the production and function of both phagocyte cells and lymphocytes. We followed up 115 patients with collagen tissue disease for two years and 22 of them had infections. Eight of these 22 patients had urinary tract infection, six had …
Infectious Diseases Concomitant With Urinary Tract Infections In Children, Ayşe Balat, L. Leighton Hill
Infectious Diseases Concomitant With Urinary Tract Infections In Children, Ayşe Balat, L. Leighton Hill
Turkish Journal of Medical Sciences
Urinary-tract infection (UTI) is one of the most common infectious diseases in children; however, the significance of combined infection in the pathogenesis of UTI remains uncertain. Of 48,382 patients discharged from Texas Children's Hospital from July 1, 1991, to June 30, 1994, 1,221 (2.5%) were discharged with a diagnosis of UTI. We retrospectively reviewed the files of these 1,221 patients to assess for concomitant infections and causative microorganisms in patients with first-time UTI, no urologic abnormalities, and no other major diagnoses. Of the 1,221 patients, 511 (42%) had first-time UTI with no urological abnormalities or other major diagnoses, of which …