Open Access. Powered by Scholars. Published by Universities.®
Articles 31 - 60 of 90
Full-Text Articles in Medicine and Health Sciences
Prevalence And Characteristics Of Hymenoptera Venom Allergy In Urban School Childrenaged 6 To 18 Years Living In Trabzon, Özge Baba, Gülay Kaya, Mehtap Haktanir Abul, Neşe Kaklikkaya, Murat Çakir, Fazil Orhan
Prevalence And Characteristics Of Hymenoptera Venom Allergy In Urban School Childrenaged 6 To 18 Years Living In Trabzon, Özge Baba, Gülay Kaya, Mehtap Haktanir Abul, Neşe Kaklikkaya, Murat Çakir, Fazil Orhan
Turkish Journal of Medical Sciences
Background/aim: Hymenoptera venom allergy is one of the leading causes of systemic allergic reactions in both adults and children. The present study was conducted to evaluate the prevalence and characteristics of Hymenoptera venom allergy in urban school children aged 6 to 18 years living in Trabzon. Materials and methods: In this cross-sectional, two-level survey study, children were recruited using random sampling of public primary and secondary schools. Firstly, parents were asked about their child's age and sex and whether their child had ever been stung by any kind of bee. When they responded "yes" to the last question, they attended …
How Safe Are Children With Covid-19 From Cardiac Risks? Pediatric Risk Assesment;Insights From Echoc, Berna Şaylan Çevi̇k, Şule Arici, Zeynep Ergenç, Eda Kepenekli̇ Kadayi̇fci̇, Özge Günal, Nurhayat Yakut
How Safe Are Children With Covid-19 From Cardiac Risks? Pediatric Risk Assesment;Insights From Echoc, Berna Şaylan Çevi̇k, Şule Arici, Zeynep Ergenç, Eda Kepenekli̇ Kadayi̇fci̇, Özge Günal, Nurhayat Yakut
Turkish Journal of Medical Sciences
Background/aim: Approximately 40 million individuals worldwide have been infected with SARS-CoV-2, the virus responsible for the novel coronavirus disease-2019 (COVID-19). Despite the current literature about the cardiac effects of COVID-19 in children, more information is required. We aimed to determine both cardiovascular and arrhythmia assessment via electrocardiographic and echocardiographic parameters. Materials and methods: We evaluated seventy children who were hospitalized with COVID-19 infections and seventy children as normal control group through laboratory findings, electrocardiography (ECG), and transthoracic echocardiography (TTE). Results: We observed significantly increased levels of Tp-Te, Tp-Te/QT, and Tp-Te/QTc compared with the control group. Twenty-five of 70 (35.7%) patients …
Retrospective Evaluation Of The Pediatric Multicystic Dysplastic Kidney Patients:Experience Of Two Centers From Southeastern Turkey, Mehtap Akbalik Kara, Aysel Taktak, Caner Alparslan
Retrospective Evaluation Of The Pediatric Multicystic Dysplastic Kidney Patients:Experience Of Two Centers From Southeastern Turkey, Mehtap Akbalik Kara, Aysel Taktak, Caner Alparslan
Turkish Journal of Medical Sciences
Background/aim: The objective of this study is to determine the clinical features of unilateral multicystic dysplastic kidney (MCDK) patients. Materials and methods: The demographic, clinical, laboratory, and radiologic features of MCDK patients at Diyarbakır Children's Hospital and Diyarbakır Gazi Yaşargil Training and Research Hospital between January 2008-June 2019 were retrospectively evaluated. Results: A total of 111 [59 (53.2%) male and 52(46.8%) female] patients with MCDK were followed for a mean period of 41.89 ± 32.03 months. MCDK was located on the left and right sides in 46 (41.4%) and 65 (58.6%) of the children, respectively (p > 0.05). A total of …
Evaluation Of S100a12 Protein Levels In Children With Familial Mediterranean Fever, Yelda Türkmenoğlu, Eli̇f Güney, Di̇ğdem Bezen, Ahmet İrdem, Bi̇ray Ertürk, Hasan Dursun
Evaluation Of S100a12 Protein Levels In Children With Familial Mediterranean Fever, Yelda Türkmenoğlu, Eli̇f Güney, Di̇ğdem Bezen, Ahmet İrdem, Bi̇ray Ertürk, Hasan Dursun
Turkish Journal of Medical Sciences
Background/aim: Familial Mediterranean fever (FMF), the most common autoinflammatory disease in children, is characterized by recurrent febrile episodes. FMF is known to progress with chronic inflammation, particularly during attack periods. This study aimed to investigate the relationship of S100A12, an inflammatory marker, with attacks and inflammatory events in FMF patients. Materials and methods: The study included 57 patients diagnosed with FMF, 43 in an attack-free period and 14 in an attack period, and 31 healthy children as the control group. Only white blood cell (WBC) count, C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), and S100A12 level were analyzed in …
Total Oxidant And Antioxidant Status And Paraoxonase 1 Levels Ofchildren With Noncystic Fibrosis Bronchiectasis, Ahmet Hakan Gedi̇k, Erkan Çakir, Aysel Vehapoğlu Türkmen, Ömer Faruk Özer, Sare Betül Kaygusuz
Total Oxidant And Antioxidant Status And Paraoxonase 1 Levels Ofchildren With Noncystic Fibrosis Bronchiectasis, Ahmet Hakan Gedi̇k, Erkan Çakir, Aysel Vehapoğlu Türkmen, Ömer Faruk Özer, Sare Betül Kaygusuz
Turkish Journal of Medical Sciences
Background/aim: To evaluate total oxidant status (TOS), total antioxidant capacity (TAC), and paraoxonase 1 (PON1) levels in children with noncystic fibrosis (CF) bronchiectasis (BE), and to compare these levels with those of healthy controls. The study parameters were also evaluated according to some demographic, anthropometric, and clinical characteristics, as well as lung functions. Materials and methods: Enrolled in the study were 118 children with non-CF BE and 68 healthy controls. Serum TOS, TAC, and PON1 levels were determined. Lung function tests were performed by spirometry. Results: Serum TOS was higher in the patients [median 9.54 (IQR 25-75 = 7.05-13.30) µmol …
The Validity And Reliability Of The Turkish Version Of The Body Esteem Scale Foradolescents And Adults (Besaa) For Children, Umut Ece Arslan, Lütfi̇ye Hi̇lal Özcebe, Hande Konşuk Ünlü, Sarp Üner, Mahmut Saadi̇ Yardim, Ozgur Araz, Terry T-K Huang
The Validity And Reliability Of The Turkish Version Of The Body Esteem Scale Foradolescents And Adults (Besaa) For Children, Umut Ece Arslan, Lütfi̇ye Hi̇lal Özcebe, Hande Konşuk Ünlü, Sarp Üner, Mahmut Saadi̇ Yardim, Ozgur Araz, Terry T-K Huang
Turkish Journal of Medical Sciences
Background/aim: Body esteem (BE) is defined as the self-evaluation of one's own body or appearance. The Body Esteem Scale for Adolescents and Adults (BESAA) consists of three subscales: BE-appearance, BE-weight, and BE-attribution. Though initially developed for adolescents and adults, the use of the scale has recently increased in health-related research on children. This study aimed to assess the validity and reliability of the Turkish version of the BESAA for children. Materials and methods: The participants in the study were 4th grade children (aged 9-10 years) in Ankara, Turkey. The validity of the scale was evaluated through exploratory and confirmatory factor …
Silent Cerebral Infarct In Sickle Cell Anemia Patients Of Southern Turkey, Ezgi̇ Nafi̇le Sayman, Göksel Leblebi̇satan, Şeri̇fe Leblebi̇satan, Yunus Kenan Biçakci, Yurdanur Kilinç, Adnan Barutçu
Silent Cerebral Infarct In Sickle Cell Anemia Patients Of Southern Turkey, Ezgi̇ Nafi̇le Sayman, Göksel Leblebi̇satan, Şeri̇fe Leblebi̇satan, Yunus Kenan Biçakci, Yurdanur Kilinç, Adnan Barutçu
Turkish Journal of Medical Sciences
Background/aim: Silent cerebral infarct (SCI) is an ischemic lesion seen before clinical signs of brain infarct and ischemic changes in brain tissue. This study aimed to detect SCI with noninvasive methods and to determine related risk factors in patients with sickle cell anemia (SCA). Materials and methods: Fifty-four SCA patients who had no history of cerebral infarct and whose neurological examinations were normal were included in this study. Brain magnetic resonance imaging (MRI) and diffusion MRI were taken and the acquired data was compared statistically. Results: SCI was detected in 11.1% (6/54) of the patients. No statistical differences in age, …
Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu
Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu
Turkish Journal of Medical Sciences
Background/aim: Non-Wilms renal tumors (NWRTs) are rarely encountered in children. The aim of this study is to determine the treatment strategies, prognosis, outcomes, and survival of children with NWRTs at Erciyes University in Kayseri, Turkey.Materials and methods: Medical records of all patients (n = 20) treated for NWRTs over a 23-year period (1995-2018) were reviewed retrospectively.Results: There was male predominance (female/male: 7/13); the median age at diagnosis was 3.2 years old (0.1-13.5 years old). The major histological groups included mesoblastic nephroma (MBN), (n: 5, 25%), malignant rhabdoid tumor (MRT), (n: 5, 25%), renal cell carcinoma, (n: 3, 15%), inflammatory myofibroblastic …
Changes In P1 Latencies Of Children With Normal Hearing And Those With Cochlear Implants, Emre Eski̇ci̇oğlu, Günay Kirkim, Selhan Gürkan, Serpi̇l Mungan Durankaya, Tahsi̇n Oğuz Başokçu, Eni̇s Alpi̇n Güneri̇
Changes In P1 Latencies Of Children With Normal Hearing And Those With Cochlear Implants, Emre Eski̇ci̇oğlu, Günay Kirkim, Selhan Gürkan, Serpi̇l Mungan Durankaya, Tahsi̇n Oğuz Başokçu, Eni̇s Alpi̇n Güneri̇
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the age-related latency interval of P1 latencies of children with normal hearing, and to evaluate the P1 latency changes after surgery in children who underwent cochlear implantation. Materials and methods: We evaluated 60 children with normal hearing and 16 children with cochlear implants aged 0-6 years using cortical auditory evoked potentials. P1 latencies were measured only once in the children with normal hearing, and on the postoperative first day, and the first, third, and sixth postoperative months in the children with cochlear implants. Results: There was a statistically significant decrease in …
Risk Factors For Bacteremia In Children With Febrile Neutropenia, Soner Sertan Kara, Hasan Tezer, Meltem Polat, Burcu Ceylan Cura Yayla, Tuğba Bedi̇r Demi̇rdağ, Arzu Okur, Ali̇ Fettah, Sali̇ha Kanik Yüksek, Anil Tapisiz, Zuhre Kaya, Namik Özbek, İdi̇l Yeni̇cesu, Hüsni̇ye Neşe Yarali, Ülker Koçak
Risk Factors For Bacteremia In Children With Febrile Neutropenia, Soner Sertan Kara, Hasan Tezer, Meltem Polat, Burcu Ceylan Cura Yayla, Tuğba Bedi̇r Demi̇rdağ, Arzu Okur, Ali̇ Fettah, Sali̇ha Kanik Yüksek, Anil Tapisiz, Zuhre Kaya, Namik Özbek, İdi̇l Yeni̇cesu, Hüsni̇ye Neşe Yarali, Ülker Koçak
Turkish Journal of Medical Sciences
Background/aim: Bacteremia remains an important cause of morbidity and mortality during febrile neutropenia (FN) episodes. We aimed to define the risk factors for bacteremia in febrile neutropenic children with hemato-oncological malignancies. Materials and methods: The records of 150 patients aged ?18 years who developed FN in hematology and oncology clinics were retrospectively evaluated. Patients with bacteremia were compared to patients with negative blood cultures.Results: The mean age of the patients was 7.5 ± 4.8 years. Leukemia was more prevalent than solid tumors (61.3% vs. 38.7%). Bacteremia was present in 23.3% of the patients. Coagulase-negative staphylococci were the most frequently isolated …
Comparative Evaluation Of Liver, Spleen, And Kidney Stiffness In Hiv-Monoinfected Pediatric Patients Via Shear Wave Elastography, Emi̇ne Çalişkan, Gürkan Atay, Manolya Kara, Murat Sütçü, Zuhal Bayramoğlu, Selda Hançerli̇ Törün, Ayper Somer, İbrahi̇m Adaletli̇
Comparative Evaluation Of Liver, Spleen, And Kidney Stiffness In Hiv-Monoinfected Pediatric Patients Via Shear Wave Elastography, Emi̇ne Çalişkan, Gürkan Atay, Manolya Kara, Murat Sütçü, Zuhal Bayramoğlu, Selda Hançerli̇ Törün, Ayper Somer, İbrahi̇m Adaletli̇
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the stiffness of the liver, spleen, and kidneys in HIV-monoinfected children via shear wave elastography (SWE).Materials and methods: Twenty-one HIV-monoinfected children and 37 healthy subjects were included in this study. Livers, spleens, and kidneys of the participants were examined via ultrasound and SWE. Patients were divided into two groups according to the presence of pathologic ultrasonographic findings. Routine laboratory tests were also recorded. Stiffness of these organs was compared between patients and control groups.Results: Liver transaminases, blood urea, and creatinine levels were normal in all subjects. Ultrasonographic examination revealed hepatosplenomegaly (n = 1, 4.7%), …
Seasonal, Sex Variations In Vitamin D Levels And Their Association With Pulmonary Function In Children With Asthma, Şebnem Özdoğan
Seasonal, Sex Variations In Vitamin D Levels And Their Association With Pulmonary Function In Children With Asthma, Şebnem Özdoğan
Turkish Journal of Medical Sciences
Background/aim: We aimed to examine the seasonal and sex variations in vitamin D levels in children with asthma and their associations with lung function. Materials and methods: We conducted a cohort study involving children aged 7?17 years old with asthma. Vitamin D levels were obtained and pulmonary function tests (PFTs) were performed in winter months (December, January, and February) and at the end of summer (August, September, and October). Seasonal and sex variations in vitamin D levels and lung function were examined. Results: A total of 56 children (26 males, mean age: 11.93 ± 1.8) were enrolled. The mean vitamin …
Influence Of Lrp5 (Rs556442) Polymorphism On Insulin Resistance In Healthy Iranian Children And Adolescents, Nima Montazeri Najafabady, Mohammad Hossein Dabbaghmanesh, Rajeeh Mohamadian-Amiri, Marzieh Bakhshayeshkaram, Gholamhossein Ranjbar Omrani
Influence Of Lrp5 (Rs556442) Polymorphism On Insulin Resistance In Healthy Iranian Children And Adolescents, Nima Montazeri Najafabady, Mohammad Hossein Dabbaghmanesh, Rajeeh Mohamadian-Amiri, Marzieh Bakhshayeshkaram, Gholamhossein Ranjbar Omrani
Turkish Journal of Medical Sciences
Background/aim: Genetic aspects play a role in insulin resistance in children. In this study, for the first time, the association of LRP5 (rs556442) polymorphism and insulin resistance in Iranian children and adolescents was investigated.Materials and methods: The study population comprises children and adolescents aged 9-18 years. Anthropometric and biochemical parameters were assessed. Insulin resistance/sensitivity was determined by the quantitative insulin sensitivity check index (QUICKI), homeostasis model assessment-insulin resistance (HOMA-IR), insulin-to-glucose ratio, McAuley index, revised McAuley index, fasting insulin resistance index (FIRI), and Bennett's index. LRP5 (rs566442) single nucleotide polymorphism (SNP) was identified using restriction fragment length polymorphism (RFLP). Linear regression …
Mesh Nebulizer Is As Effective As Jet Nebulizer In Clinical Practice Of Acute Asthma In Children, Özge Uysal Soyer, Meli̇ke Kahveci̇, Ayşe Betül Büyükti̇ryaki̇, Ebru Arik Yilmaz, Betül Karaatmaca, Sali̇ha Esenboğa, Pinar Gür Çeti̇nkaya, Ümi̇t Murat Şahi̇ner, Bülent Eni̇s Şekerel
Mesh Nebulizer Is As Effective As Jet Nebulizer In Clinical Practice Of Acute Asthma In Children, Özge Uysal Soyer, Meli̇ke Kahveci̇, Ayşe Betül Büyükti̇ryaki̇, Ebru Arik Yilmaz, Betül Karaatmaca, Sali̇ha Esenboğa, Pinar Gür Çeti̇nkaya, Ümi̇t Murat Şahi̇ner, Bülent Eni̇s Şekerel
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to compare the effect of salbutamol delivered to children by jet nebulizer (JN) and mesh nebulizer (MN). Materials and methods: Children admitted with acute asthma were treated with 3 doses of nebulized salbutamol, 1 given by MN. The patients' vital signs, lung function measurements, modified pulmonary index score (MPIS), and whole body plethysmography (WBP) measurements were evaluated before and 20 min after each dose of salbutamol.Results: Thirty-onechildren [9.5 (6.4-17.2) years, 67.7% male, 32.3% female] with mild (67.7%) and moderate (32.3%) asthma attacks were included in the study. The improvements with MN were comparable …
High Rates Of Malnutrition And Epilepsy: Two Common Comorbidities In Children With Cerebral Palsy, Kürşad Aydin, Ayşe Kartal, Esma Keleş Alp
High Rates Of Malnutrition And Epilepsy: Two Common Comorbidities In Children With Cerebral Palsy, Kürşad Aydin, Ayşe Kartal, Esma Keleş Alp
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the nutritional status of children with cerebral palsy and determine the particular characteristics of the disorder. Materials and methods: The nutritional status of the children was assessed by the Gomez classification using weight-for-age. The Gross Motor Function Classification System was used to determine the gross and fine motor functions.Results: The study was conducted with 197 children (58.4% males) between the ages of 1 and 18 years old. Asphyxia (44.1%) was the primary etiological factor, and spastic quadriplegia (41.6%) was the most common type of cerebral palsy. Malnutrition was the most frequent comorbidity …
Comparison Of Reference Systems In The Assessment Of Age-Related Serum Immunoglobulin Levels In Pediatric Patients, İlknur Külhaş Çeli̇k, Ersoy Ci̇velek, Ayşe Meti̇n, Tayfur Gi̇ni̇ş, Müge Toyran, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
Comparison Of Reference Systems In The Assessment Of Age-Related Serum Immunoglobulin Levels In Pediatric Patients, İlknur Külhaş Çeli̇k, Ersoy Ci̇velek, Ayşe Meti̇n, Tayfur Gi̇ni̇ş, Müge Toyran, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
Turkish Journal of Medical Sciences
Ig level assessment is frequently used in the diagnosis and follow-up of immunodeficiency, as well as in studies investigating the prevalence of low serum Ig level in specific diseases.Material and methods: Patients who underwent Ig testing in the inpatient and outpatient clinics of our hospital in the years 2010-2016 were included. The Ig levels of the patients were assessed separately according to two reference systems commonly used in Turkey and another reference system used in the USA.Results: A total of 20,138 patients (57.6% male) were included in the study. The median age of the patients was 55.7 months (interquartile range: …
Emotion Regulation And Premedication Success Relationship In Children Who Underwent General Anesthesia, Aslihan Aykut, Berri̇n Işik
Emotion Regulation And Premedication Success Relationship In Children Who Underwent General Anesthesia, Aslihan Aykut, Berri̇n Işik
Turkish Journal of Medical Sciences
Background/aim: is study aims to investigate the relationship between emotion regulation characteristics and the e cacy of midazolam premedication. Materials and methods: Sixty-three children, aged 3 to 8 years old, with tonsillectomy and/or adenoidectomy and taking premedication with midazolam (Group 2) or without premedication (Group 1), were included in this study. e behavioral and emotional status of the children was evaluated with the Conners Parent Rating Scale-48 (CPRS-48) and Emotion Regulation Checklist (ERC). Age, sex, body weight, response to intravenous (IV) cannulation and mask, hemodynamic data, preoperative sedation scores [Wilton Sedation Scale (WSS)], postoperative pain intensity [Objective Pain Scale (OPS)], …
An Evaluation Of Banana Allergy In Children Living In The Mediterranean Region, Di̇lara Fatma Kocacik Uygun, Serkan Fi̇li̇z, Ayşen Bi̇ngöl
An Evaluation Of Banana Allergy In Children Living In The Mediterranean Region, Di̇lara Fatma Kocacik Uygun, Serkan Fi̇li̇z, Ayşen Bi̇ngöl
Turkish Journal of Medical Sciences
Background/aim: We aimed to apply a double-blind placebo-controlled food challenge (DBPCFC) test to patients who reported a reaction to banana and showed positivity for banana-specific IgE in Turkey. Materials and methods: Medical data of patients who had been analyzed for banana allergy were reviewed, focusing on banana-specific IgE positivity at the Department of Pediatric Allergy-Immunology at the Akdeniz University Faculty of Medicine between the years 2004 and 2012. Patients were called to the clinic for a DBPCFC test. Results: A total of 47 patients participated. We determined reactions in 13% of DBPCFC patients. A cut-off value was determined as 0.66 …
Serum Vasohibin-1 And Suppression Of Tumorigenicity-2 Levels In Children Withpredialysis Chronic Kidney Disease, Nuran Çeti̇n, Nadi̇de Meli̇ke Sav
Serum Vasohibin-1 And Suppression Of Tumorigenicity-2 Levels In Children Withpredialysis Chronic Kidney Disease, Nuran Çeti̇n, Nadi̇de Meli̇ke Sav
Turkish Journal of Medical Sciences
Background/aim: Chronic kidney disease (CKD), which is one of the most important health problems worldwide, could be considered as an immune inflammatory disease. A prognostic biomarker may be helpful in determining the progression of CKD in children. We aimed to investigate the serum vasohibin-1 and soluble suppression of tumorigenicity-2 (sST2) levels as potential biomarkers in children with predialysis CKD. Materials and methods: Forty-seven children with stage 2-4 CKD and 20 healthy controls were included in this cross-sectional study. Glomerular filtration rate (GFR) and urinary excretion of protein were measured in 24-h urine samples. Serum vasohibin-1 levels and sST2 were measured. …
Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay
Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay
Turkish Journal of Medical Sciences
Background/aim: Understanding the causes of under-five deaths is key to realizing sustainable developmental goals. The aim of this descriptive study was to investigate the causes of under-five mortality in İstanbul during 2011 and compare the findings to those of 1988 and 2000. Materials and methods: All burial records of İstanbul were evaluated, and cemetery records of 1494 children, who died at under five years of age and were buried in İstanbul Metropolitan Municipality Cemeteries between 1 January and 31 December 2011, were analyzed. Several sociodemographic characteristics and causes of death were compared with the results of studies carried out in …
Predictors Of Health Related Quality Of Life In Childhood Epilepsy And Comparison Withhealthy Children: Findings From An Indian Study, Dipika Bansal, Chandrika Azad, Kapil Gudala, Anil Dasari
Predictors Of Health Related Quality Of Life In Childhood Epilepsy And Comparison Withhealthy Children: Findings From An Indian Study, Dipika Bansal, Chandrika Azad, Kapil Gudala, Anil Dasari
Turkish Journal of Medical Sciences
Background/aim: Children with epilepsy have reduced health-related quality of life (HRQOL) due to disease and medications. We aimed to assess child-reported HRQOL in Indian children with epilepsy and compare it with that in healthy children. Materials and methods: A cross-sectional study of 256 children with epilepsy aged between 5 and 18 years on antiepileptic drug (AED) treatment for at least 3 months was performed and 125 age and sex matched healthy children were included. A generic version of the Pediatric Quality of Life (PedsQL version 4) scale was used to assess HRQOL. Results: Children with epilepsy had diminished scores in …
Effect Of Inhaled Steroids On Clinical And Inflammatoryparameters In Children With Cystic Fibrosis, Zeynep Seda Uyan, Gökseni̇n Ünlügüzel Üstün, Goncagül Haklar, Erkan Çakir, Sedat Oktem, Refi̇ka Ersu, Bülent Taner Karadağ, Fazi̇let Karakoç, Eli̇f Dağli
Effect Of Inhaled Steroids On Clinical And Inflammatoryparameters In Children With Cystic Fibrosis, Zeynep Seda Uyan, Gökseni̇n Ünlügüzel Üstün, Goncagül Haklar, Erkan Çakir, Sedat Oktem, Refi̇ka Ersu, Bülent Taner Karadağ, Fazi̇let Karakoç, Eli̇f Dağli
Turkish Journal of Medical Sciences
Background/aim: The effectiveness of inhaled corticosteroids (ICSs) in cystic fibrosis (CF) is controversial. The aim of this study was to investigate the effect of an ICS on bronchial hyperreactivity (BHR), oxidative status, and clinical and inflammatory parameters in CF patients. Materials and methods: CF patients were randomized to receive either 2 mg/day nebulized budesonide or 0.9% normal saline as placebo for 8 weeks. Results: Twenty-nine CF patients (mean age: 10.5 $\pm$ 2.9 years) were enrolled in the study. There was no statistically significant difference between the two groups at the end of 8 weeks in terms of symptoms, pulmonary function, …
Allergic And Autoimmune Disorders In Families With Selective Iga Deficiency, Mustafa Erkoçoğlu, Ayşe Meti̇n, Ayşenur Kaya, Celal Özcan, Ayşegül Akan, Ersoy Ci̇velek, Murat Çapanoğlu, Tayfur Gi̇ni̇ş, Can Naci̇ Kocabaş
Allergic And Autoimmune Disorders In Families With Selective Iga Deficiency, Mustafa Erkoçoğlu, Ayşe Meti̇n, Ayşenur Kaya, Celal Özcan, Ayşegül Akan, Ersoy Ci̇velek, Murat Çapanoğlu, Tayfur Gi̇ni̇ş, Can Naci̇ Kocabaş
Turkish Journal of Medical Sciences
Background/aim: IgA deficiency is the most common human primary immunodeficiency. The prevalence of allergic disorders and autoimmunity is thought to be increased in selective IgA deficiency (sIgAD). However, it is currently unclear if these disorders coincide within these families. We aimed to evaluate the frequency of allergic and autoimmune disorders in children with sIgAD and their firstdegree relatives (FDRs). Materials and methods: The study included 81 children diagnosed with sIgAD and 274 of their FDRs. The presence of allergic and autoimmune disorders was evaluated and serum antithyroglobulin and antithyroid peroxidase levels were measured in both patients and their first-degree relatives. …
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Turkish Journal of Medical Sciences
Background/aim: Diabetes mellitus (DM) is one of the most common metabolic diseases seen in the world today. Diabetic neuropathy (DN) is a chronic complication of the disease that is rarely reported in children, since it has a relatively longer latency period. Our main objective in this study is to determine the incidence rate of DN in pediatric DM patients and assess the risk factors associated with DN. Materials and methods: Data from 111 patients from January 2011 to May 2014 were reviewed in a retrospective manner. Nerve conduction studies were performed as the gold standard in diagnosis. Results: The incidence …
Detection And Molecular Characterisation Of Adenovirus In Children Under 5 Years Old With Diarrhoea, Meryem Çolak, Gülendam Bozdayi, Ayli̇n Altay, Zahi̇de Yalaki̇, Kamruddi̇n Ahmed, Seçi̇l Özkan
Detection And Molecular Characterisation Of Adenovirus In Children Under 5 Years Old With Diarrhoea, Meryem Çolak, Gülendam Bozdayi, Ayli̇n Altay, Zahi̇de Yalaki̇, Kamruddi̇n Ahmed, Seçi̇l Özkan
Turkish Journal of Medical Sciences
Background/aim: To determine the frequency, genotype distribution, and genetic relatedness of adenoviruses in children under 5 years old with diarrhoea and to investigate their distribution according to clinical findings, age, months, and seasons. Materials and methods: Stool samples were collected from 180 children with acute gastroenteritis who presented from July 2007 through June 2011 at the Ankara Training and Education Hospital. Stool samples were analysed by immune chromatographic test (ICT), enzyme immunoassay (EIA), and polymerase chain reaction (PCR). All adenovirus types were determined by nucleotide sequence analysis. A phylogenetic tree was constructed by Mega 6.0 using the neighbour-joining method. Results: …
Physical Activity And Physical Fitness In Obese, Overweight, And Normal-Weight Children, Juozas Raistenskis, Aurelija Sidlauskiene, Birute Strukcinskiene, Serpi̇l Uğur Baysal, Raimondas Buckus
Physical Activity And Physical Fitness In Obese, Overweight, And Normal-Weight Children, Juozas Raistenskis, Aurelija Sidlauskiene, Birute Strukcinskiene, Serpi̇l Uğur Baysal, Raimondas Buckus
Turkish Journal of Medical Sciences
Background/aim: The aim was to assess the differences between physical activity and physical fitness in obese, overweight, and normal-weight children. Materials and methods: The cross-sectional study was accomplished using cluster sampling method at 3 Lithuanian schools. An analysis of anthropometric data for 532 Lithuanian children was performed. Height, weight, waist and hip circumferences, and skinfold thickness were measured. Body mass index, waist-to-hip ratio, and body fat percentage were calculated. The Youth Physical Activity Questionnaire and a 6-min walk test (6MWT) were administered to evaluate physical activity and physical fitness. Maximal oxygen consumption was calculated to assess the children's aerobic capacity. …
Sensitization To Food And Inhalant Allergens In Healthy Children In Van, East Turkey, Mehmet Parlak, Ayteki̇n Çikman, Yasemi̇n Bayram, Nesri̇n Ceylan, Ulaş Çalişir, Mustafa Berktaş
Sensitization To Food And Inhalant Allergens In Healthy Children In Van, East Turkey, Mehmet Parlak, Ayteki̇n Çikman, Yasemi̇n Bayram, Nesri̇n Ceylan, Ulaş Çalişir, Mustafa Berktaş
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to determine the most frequent food and inhalant allergens leading to allergic sensitization in children in Van Province of Turkey. Materials and methods: The study included 1052 serum samples with no diagnosis of allergy. The sera were tested with the Euroline Pediatric IgE test kit (EUROIMMUN, Germany). By using the EUROLineScan digital evaluation system, the intensity of bands was calculated with enzyme allergosorbent test classification. Results: Out of the 1052 tested sera, 143 were found to be cross-reactive carbohydrate determinant-positive and were discarded from the study. Of the remaining 909 sera, 513 (56%) …
Health-Related Quality Of Life Of Pediatric Renal Transplant Recipientsand Their Parents: The Role Of Associated Factors And Clinical Counseling, Bahar Büyükkaragöz, Necla Buyan, Nahi̇de Doğrucan, Bülent Çeli̇k
Health-Related Quality Of Life Of Pediatric Renal Transplant Recipientsand Their Parents: The Role Of Associated Factors And Clinical Counseling, Bahar Büyükkaragöz, Necla Buyan, Nahi̇de Doğrucan, Bülent Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: This study evaluates the health-related quality of life (HRQoL) of pediatric renal transplant recipients and their parents and investigates the effects of clinical, socioeconomic, and psychological factors as well as continuous counseling on the HRQoL. Materials and methods: Patients aged 8-17 years (mean: 14.9 ± 2.9) were enrolled. Clinical and demographic data were noted. The Beck Depression Inventory (BDI), Rosenberg Self-Esteem Scale (RSES), and Turkish version of the Kinder Lebensqualität Fragebogen (KINDL) questionnaire for children and the BDI, RSES, parent-proxy version of KINDL, and Short-Form 36 (SF-36) for parents were applied (step 1). Following a 1-year counseling program, the …
Pityriasis Rosea: A Natural History Of Pediatric Cases In Thecentral Anatolia Region Of Turkey, Emi̇ne Çölgeçen, Çi̇ğdem Kader, Yilmaz Ulaş, Pinar Öztürk, Öznur Küçük, Mehmet Balci
Pityriasis Rosea: A Natural History Of Pediatric Cases In Thecentral Anatolia Region Of Turkey, Emi̇ne Çölgeçen, Çi̇ğdem Kader, Yilmaz Ulaş, Pinar Öztürk, Öznur Küçük, Mehmet Balci
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the demographic, clinical, and epidemiological features of pityriasis rosea (PR) in a cohort of 46 children in Yozgat, a city in the Central Anatolia Region of Turkey. Materials and methods: Forty-six children with PR were monitored at regular intervals (1, 2, 4, and 12 weeks) for 3 months from the time of diagnosis. A complete evaluation of the patient was performed at each visit. Results: The average age of patients at time of diagnosis was 12 ± 3.9 years. Cases were most common in the winter (rainy, snowy months; n = 14, 31%). Fifteen …
Bone Mineral Density And Growth In Children With Coeliac Disease On A Gluten Free-Diet, Ceyda Tuna Kirsaçlioğlu, Zari̇fe Kuloğlu, Aydan Tanca, Nuri̇ye Özlem Küçük, Zehra Aycan, Gönül Öçal, Arzu Ensari̇, Ayhan Gazi̇ Kalayci, Nurten Gi̇rgi̇n
Bone Mineral Density And Growth In Children With Coeliac Disease On A Gluten Free-Diet, Ceyda Tuna Kirsaçlioğlu, Zari̇fe Kuloğlu, Aydan Tanca, Nuri̇ye Özlem Küçük, Zehra Aycan, Gönül Öçal, Arzu Ensari̇, Ayhan Gazi̇ Kalayci, Nurten Gi̇rgi̇n
Turkish Journal of Medical Sciences
Background/aim: To evaluate changes in growth and bone metabolism during consumption of a gluten-free diet (GFD) in children with coeliac disease (CD). Materials and methods: Thirty-seven children with CD (mean age of 8.8 ± 4.6 years, 21 girls) were enrolled. Anthropometric measurements, bone mineral density (BMD) in lumbar 2-4 vertebrae, and serum alkaline phosphatase, calcium, and phosphorus levels at diagnosis and at follow-up were recorded. Results: The mean follow-up period was 3.5 ± 2.3 years. The BMD of patients was significantly lower than that of control subjects at the time of diagnosis but not after 1 year of the GFD. …