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Articles 1 - 30 of 52
Full-Text Articles in Medicine and Health Sciences
Relationship Between C-Reactive Protein/Albumin Ratio And Mucocutaneous Symptom Frequency And Disease Severity In Behçet’S Disease, Erdal Pala, Mustafa Bayraktar
Relationship Between C-Reactive Protein/Albumin Ratio And Mucocutaneous Symptom Frequency And Disease Severity In Behçet’S Disease, Erdal Pala, Mustafa Bayraktar
Turkish Journal of Medical Sciences
Background/aim: There is no specific marker that can be applied to determine the severity of Behçet’s disease. The aim of this study is to investigate the potential of C-reactive protein (CRP)/albumin (CAR) ratio as a tool for assessing the severity of Behçet’s disease.Materials and methods: A retrospective crosssectional study was conducted by examining hospital archives. The CRP and albumin levels of Behçet’s disease patients who presented to our dermatology clinic over a three-year period from February 2020 to February 2022 were included, along with the identical laboratory parameters in the control group. The CAR ratio was calculated and statistically compared …
Serum And Urine Interferon-Inducible Protein 10, Galectin-9, And Siglec-1 As Biomarkers Of Disease Activity In Systemic Lupus Erythematosus, Şafak Mi̇ri̇oğlu, Suzan Çinar, Ömer Uludağ, Erdem Gürel, Sibel Varelci̇, Yasemin Özlük, Işın Kiliçaslan, Yasemin Yalçinkaya, Halil Yazici, Ahmet Gül, Murat İnanç, Bahar Artim Esen
Serum And Urine Interferon-Inducible Protein 10, Galectin-9, And Siglec-1 As Biomarkers Of Disease Activity In Systemic Lupus Erythematosus, Şafak Mi̇ri̇oğlu, Suzan Çinar, Ömer Uludağ, Erdem Gürel, Sibel Varelci̇, Yasemin Özlük, Işın Kiliçaslan, Yasemin Yalçinkaya, Halil Yazici, Ahmet Gül, Murat İnanç, Bahar Artim Esen
Turkish Journal of Medical Sciences
Background/aim: In this prospective study, we aimed to investigate the association of serum (s) and urine (u) IP-10, galectin-9, and SIGLEC-1 with disease activity in patients with systemic lupus erythematosus (SLE).Materials and methods: Sixty-three patients with active SLE (31 renal, 32 extrarenal) were included. Thirty patients with inactive SLE (15 renal, 15 extrarenal), 17 with renal active AAV, and 32 healthy volunteers were selected as control groups. Serum and urine IP-10, galectin-9, and SIGLEC-1 were tested using ELISA.Results: Levels of sIP-10 (p = 0.046), uIP-10 (p < 0.001), sGalectin-9 (p = 0.03), and uSIGLEC-1 (p = 0.006) were significantly higher in active SLE group compared to the inactive SLE; however, no differences were detected in the comparison of uGalectin-9 (p = 0.18) and sSIGLEC-1 (p = 0.69) between two groups. None of the biomarkers discriminated patients with active renal SLE from active extrarenal SLE. ROC analyses revealed an AUC of 0.63 (0.52–0.73) for sIP-10, 0.78 (0.68–0.86) for uIP-10, 0.64 (0.53–0.74) for sGalectin-9, and 0.68 (0.57–0.77) for uSIGLEC-1 in discriminating disease activity in SLE, which did not outperform C3 (0.75, 0.64–0.84) and C4 (0.72, 0.61–0.82). sIP-10 (p = 0.001), uIP-10 (p = 0.042), and uGalectin-9 (p = 0.009) were significantly increased in patients with active renal SLE compared to active renal AAV. sGalectin-9 (p < 0.001) and sIP-10 levels (p = 0.06) were decreased after 8 (5–22.5) months of treatment.Conclusion: sIP-10, uIP-10, sGalectin-9, and uSIGLEC-1 reflect global disease activity in SLE but do not outperform C3 and C4. sIP-10 and uIP-10 may be specific for active SLE compared to active AAV. sIP-10 and sGalectin-9 might be valuable in monitoring response after treatment.
Antiobesity And Antidyslipidemic Properties Of Clitoria Ternatea Petals Aqueous Extract Against Rats Induced By High-Fat Diet, I Gede Aswin Parisya Sasmana, Desak Made Wihandani, I Gede Krisna Arim Sadeva, Wilson Halim, Putu Putri Agustini, Lalita Samala, I Gusti Ngurah Agung Surya Pratama, Lidiya Nuraliza Rachmawati, Aizar Vesa Prasetyo, Ni Komang Ayu Amanda Setiari Jaya
Antiobesity And Antidyslipidemic Properties Of Clitoria Ternatea Petals Aqueous Extract Against Rats Induced By High-Fat Diet, I Gede Aswin Parisya Sasmana, Desak Made Wihandani, I Gede Krisna Arim Sadeva, Wilson Halim, Putu Putri Agustini, Lalita Samala, I Gusti Ngurah Agung Surya Pratama, Lidiya Nuraliza Rachmawati, Aizar Vesa Prasetyo, Ni Komang Ayu Amanda Setiari Jaya
Turkish Journal of Medical Sciences
Background/aim: Obesity is a chronic metabolic disease involving dysregulation of fat metabolism that affects 13% of the world’s population. Obesity has been linked to dyslipidemia with a lot of complication, including stroke, chronic kidney disease, fatty liver disease, and so on. One of the natural resources that have several potential effects including anticholesterol, antiobesity, and antidyslipidemia is the butterfly pea (Clitoria ternatea/CT). CT’s petal has been found to contain high levels of anthocyanins and tannins that can inhibit the biosynthesis of cholesterol and lipid. This study aims to investigate the antiobesity and antidyslipidemic effects of Clitoria ternatea extract (CTE).Materials and …
Evaluation Of Smoking Cessation Counseling Practices Of Physicians Working In Primary Health Care Institutions, Fatma Nur Karaçorlu, Edibe Pi̇ri̇nçci̇
Evaluation Of Smoking Cessation Counseling Practices Of Physicians Working In Primary Health Care Institutions, Fatma Nur Karaçorlu, Edibe Pi̇ri̇nçci̇
Turkish Journal of Medical Sciences
Background/aim: In this study, we aimed to evaluate the self-reported practice of physicians working in primary health care institutions in Elazığ Province about smoking cessation counseling.Materials and methods: The population of this cross-sectional study consisted of 262 physicians working in primary health care institutions in Elazığ. We aimed to reach the entire population without using the sample selection method and we successfully reached 95.42% (250 people) of the population. A questionnaire form was used for data collection. The data obtained were evaluated by frequency, percentage, mean ± standard deviation, median and minimum–maximum, and binary logistic regression analysis.Results: The mean age …
Internal Mucosal Resection And Llc Suspension: A New Method To Establish A Stable Tip Rotation Angle And Reduce The Nasal Bridge Length, Mehmet Dadaci, Moath Zuhour, Bilsev İnce, Zeynep Altuntaş
Internal Mucosal Resection And Llc Suspension: A New Method To Establish A Stable Tip Rotation Angle And Reduce The Nasal Bridge Length, Mehmet Dadaci, Moath Zuhour, Bilsev İnce, Zeynep Altuntaş
Turkish Journal of Medical Sciences
Background/aim: Herein, we describe a new technique to obtain both the appropriate degree of rotation angle and the ideal nasal bridge length. The aim of this study is to investigate the long-term results of this new technique with regard to these two variables.Materials and methods: A total of 76 (27 males, 49 females) patients were operated in accordance with the presented technique. Internal caudal mucosal excision and lower lateral cartilage (LLC) suspension were applied to all the patients included in this prospective study. Preoperative, immediate postoperative, and postoperative 1st-year photographs were taken. NOSE scores were obtained in the postoperative 1st …
Developing Patient Safety Scale For Hospitals, Metin Di̇nçer, Esra Karataş Okyay, Yunus Emre Karataş, Erol Göral
Developing Patient Safety Scale For Hospitals, Metin Di̇nçer, Esra Karataş Okyay, Yunus Emre Karataş, Erol Göral
Turkish Journal of Medical Sciences
Background/aim: The study aimed to contribute to the literature with a reliable and valid scale for hospitals to be used in determining the current patient safety culture and following up on its development.Materials and methods: The study was conducted with the participation of 1137 healthcare professionals selected using the convenience sampling method in 3 secondary-care state hospitals and three research and training hospitals, one of which was affiliated with a medical faculty, and two were affiliated with the Health Sciences University. To begin with, to discover the latent structure of the items on the scale, an Exploratory Factor Analysis (EFA) …
The Outcome In Pediatric Acute Myeloblastic Leukemia; Results Of The First-Line Treatment And Contribution Of Hematopoietic Stem Cell Transplantation To Survival Of Relapsed Patients, Nazan Sarper, Intzi Tachzin, Sema Aylan Gelen, Emine Zengi̇n
The Outcome In Pediatric Acute Myeloblastic Leukemia; Results Of The First-Line Treatment And Contribution Of Hematopoietic Stem Cell Transplantation To Survival Of Relapsed Patients, Nazan Sarper, Intzi Tachzin, Sema Aylan Gelen, Emine Zengi̇n
Turkish Journal of Medical Sciences
Background/aim: To analyze the long-term outcome of pediatric patients with acute myeloblastic leukemia.Materials and methods: Data from 69 patients 0–18 years of age diagnosed between December 2001 and October 2019 were analyzed in April 2023. Patients received MRC-AML10 chemotherapy (2ADE+MACE+MidAC). No maintenance chemotherapy or preventive cranial radiotherapy was administered. Twelve patients with Down syndrome and 15 patients with promyelocytic leukemia were in the cohort. Patients with Down syndrome received reduced chemotherapy (cumulative anthracycline 420 mg/m2, cytarabine 3.4 g/m2, etoposide 1400 mg/m2). ATRA was added to chemotherapy in promyelocytic leukemia.Results: Four patients (5.8%) died in the induction (two typhlitis, one intracranial …
Small Airway Resistance In Obese And Nonobese Patients With Obstructive Sleep Apnea Syndrome Using Impulse Oscillometry, Nejdiye Güngördü, Aytan İsmayi̇lova, Nigar Ali̇yeva, Tamer A M Alhelou, Ayşenur Özdi̇l Eser, Ilgım Vardaloğlu Koyuncu, Nihal Enşen, Ersan Atahan, Şermin Börekçi̇, Bilun Gemi̇ci̇oğlu
Small Airway Resistance In Obese And Nonobese Patients With Obstructive Sleep Apnea Syndrome Using Impulse Oscillometry, Nejdiye Güngördü, Aytan İsmayi̇lova, Nigar Ali̇yeva, Tamer A M Alhelou, Ayşenur Özdi̇l Eser, Ilgım Vardaloğlu Koyuncu, Nihal Enşen, Ersan Atahan, Şermin Börekçi̇, Bilun Gemi̇ci̇oğlu
Turkish Journal of Medical Sciences
Background/aim: There is limited information on the pathologic changes in the small airways among obese and nonobese patients with obstructive sleep apnea syndrome (OSAS). Impulse oscillometry (IOS) measures airway resistance and reactance independently of patient effort. This study aimed to compare airway resistance in small airways using IOS between obese and nonobese patients with OSAS.Materials and methods: In this real-life cross-sectional study, demographic information was collected from obese and nonobese subjects diagnosed with moderate and severe OSAS without any other underlying diseases. Spirometry and IOS measurements were conducted, and the values of both groups were statistically analyzed.Results: The nonobese group …
The Effect Of Human Recombinant Epidermal Growth Factor On Neovascularization And Pedicle Division Time In A Rat Interpolation Flap Model, Aziz Parspanci, Yavuz Keçeci̇, Peyker Temi̇z
The Effect Of Human Recombinant Epidermal Growth Factor On Neovascularization And Pedicle Division Time In A Rat Interpolation Flap Model, Aziz Parspanci, Yavuz Keçeci̇, Peyker Temi̇z
Turkish Journal of Medical Sciences
Background/aim: In practice, waiting 2–3 weeks for interpolation flaps pedicle division result in certain morbidities and discomfort for patient. The division time of flap pedicle depends on neovascularization from the recipient bed and includes wound healing stages. We aimed to investigate the effect of recombinant human epidermal growth factor (rhEGF) on the flap viability during early pedicle division.Materials and methods: Thirty-six rats were allocated to two main groups as control and study. A cranial based flap measuring 5 × 5 cm was elevated from the back, including all layers of the skin. While the cranial half of the defect was …
Displaced Sigmoid Notch Fracture And Higher Patient Age Are Associated With Distal Radioulnar Joint Subluxation, Saygın Kamaci, Melih Oral, Engin Türkay Yilmaz, Taha Aksoy, Barış Kafa, Mazhar Tokgözoğlu
Displaced Sigmoid Notch Fracture And Higher Patient Age Are Associated With Distal Radioulnar Joint Subluxation, Saygın Kamaci, Melih Oral, Engin Türkay Yilmaz, Taha Aksoy, Barış Kafa, Mazhar Tokgözoğlu
Turkish Journal of Medical Sciences
Background/aim : Distal radius fractures (DRFs) are frequently associated with distal radioulnar joint (DRUJ) instability. The purpose of this study is to evaluate the effect of the sigmoid notch and ulna styloid fracture types on DRUJ subluxation following closed reduction and casting of DRFs via calculating radioulnar ratio (RUR) on post-reduction computed tomography (CT) images. Materials and methods: In our study, post-reduction CT images of 202 patients with distal radius fractures was evaluated retrospectively. CT images were evaluated for RUR, sigmoid notch fracture, and ulna styloid types. Sigmoid notch fractures were classified as non-displaced in the sigmoid notch fractures (NDS) …
Clinical, Radiological, And Surgical Outcomes Of 431 Patients With Adrenal Incidentalomas: Retrospective Study Of A 10-Year Single-Center Experience, Nari̇n Nasiroğlu İmga, Yılmaz Aslan, Merve Çatak, İbrahim Can Aykanat, Altuğ Tuncel, Dilek Berker
Clinical, Radiological, And Surgical Outcomes Of 431 Patients With Adrenal Incidentalomas: Retrospective Study Of A 10-Year Single-Center Experience, Nari̇n Nasiroğlu İmga, Yılmaz Aslan, Merve Çatak, İbrahim Can Aykanat, Altuğ Tuncel, Dilek Berker
Turkish Journal of Medical Sciences
Background/aim: The incidence of adrenal tumors is increasing due to the widespread utilization of radiographic imaging techniques. Factors such as tumor size, radiological characteristics, and functionality of adrenal adenomas play crucial roles in diagnosis and subsequent management. In this retrospective study, we investigated the clinical, radiological, and surgical features of patients with adrenal incidentalomas (AIs) and evaluated their follow-up results.Materials and methods: We analyzed data from 431 patients diagnosed with AIs (130 males, 301 females) who underwent adrenal hormone evaluation at our center. We compared nonfunctioning and functioning AIs in terms of radiological features. We also compared baseline and follow-up …
Preoperative Parent Education And Postoperative Nurse-Led Care For Boys Versus Routine Hospital Care For Urethroplasty For Hypospadias In Western China: A Retrospective Study, Lisi Wang, Zhengdong Wang, Xiaohui Mao, Yingjun Fu, Qian Lei, Qin Liao
Preoperative Parent Education And Postoperative Nurse-Led Care For Boys Versus Routine Hospital Care For Urethroplasty For Hypospadias In Western China: A Retrospective Study, Lisi Wang, Zhengdong Wang, Xiaohui Mao, Yingjun Fu, Qian Lei, Qin Liao
Turkish Journal of Medical Sciences
Background/aim: Urethroplasty is the preferred treatment for hypospadias but is affected by the severity of anomalies, making it a complex procedure with potential postoperative complications. Following surgery, parents receive instructions and recommendations, whether from nurses or physicians, regardless of complication rates. However, nurses play a crucial role in educating caregivers before surgery and providing postoperative care during follow-up. The study aims to assess parents’ knowledge and practices, as well as the frequency of complications in boys who underwent urethroplasty for hypospadias and received postoperative nurse-led care and whose parents received preoperative education against those of boys who underwent urethroplasty under …
The Relationship Between Trunk Control, Spinal Posture, And Spinal Mobility In Patients With Multiple Sclerosis: A Cross-Sectional Study, Taşkın Özkan, Nezehat Özgül Ünlüer, Mustafa Ertuğrul Yaşa, Buse Korkmaz, Gönül Vural
The Relationship Between Trunk Control, Spinal Posture, And Spinal Mobility In Patients With Multiple Sclerosis: A Cross-Sectional Study, Taşkın Özkan, Nezehat Özgül Ünlüer, Mustafa Ertuğrul Yaşa, Buse Korkmaz, Gönül Vural
Turkish Journal of Medical Sciences
Trunk control, which plays a key role in balance and mobility, decreases in patients with multiple sclerosis (PwMS) and many parameters such as sensory, motor, and musculoskeletal systems affect trunk control. The aim of this study was to compare trunk control, spinal mobility, and spinal posture in PwMS with healthy controls and investigate the relationship between trunk control with spinal posture and spinal mobility in PwMS.Materials and methods: The study was completed with 38 PwMS and 38 healthy controls with matched age and sex. Trunk control was evaluated with the Trunk Impairment Scale (TIS). Spinal posture and mobility were evaluated …
Evaluation Of Accompanying Allergic Disease In Children With Proven Drug Allergies, Şule Büyük Yaytokgi̇l, Kezban İpek Demi̇r, Özge Yılmaz Topal, Azize Pınar Metbulut, İlknur Külhaş Çeli̇k, Müge Toyran, Ersoy Ci̇velek, Emine Di̇bek Misirlioğlu
Evaluation Of Accompanying Allergic Disease In Children With Proven Drug Allergies, Şule Büyük Yaytokgi̇l, Kezban İpek Demi̇r, Özge Yılmaz Topal, Azize Pınar Metbulut, İlknur Külhaş Çeli̇k, Müge Toyran, Ersoy Ci̇velek, Emine Di̇bek Misirlioğlu
Turkish Journal of Medical Sciences
Data on the prevalence of allergic diseases in children with proven drug allergies are limited. We aim to evaluate thefrequency of allergic comorbidity in children with proven common drug allergies.Materials and methods: Children with drug hypersensitivity confirmed by diagnostic allergy tests at our center between January 2010and December 2020 were screened retrospectively. Patients with the most common drug allergies (due to antibiotics, nonsteroidalantiinflammatory drugs [NSAIDs], and antiepileptic drugs) were selected for analysis. Age, sex, the culprit drug, initial reactioncharacteristics, diagnostic test results, and the study physician who diagnosed concomitant allergic diseases were noted.Results: A total of 168 patients (boys, 51.2%) …
Evaluation Of Bone Health In Terms Of Osteoporosis In Adult Patients With Neuromuscular Disease, Özgür Zeliha Karaahmet, Eda Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Zeynep Tuba Bahti̇yarca, Ebru Umay
Evaluation Of Bone Health In Terms Of Osteoporosis In Adult Patients With Neuromuscular Disease, Özgür Zeliha Karaahmet, Eda Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Zeynep Tuba Bahti̇yarca, Ebru Umay
Turkish Journal of Medical Sciences
There are no current guidelines to help clinicians decide whether patients with adult neuromuscular disease (NMD) should be screened or treated for osteoporosis (OP). This study was undertaken to investigate the presence of OP in patients with various types of NMD and to examine the relationship between OP evaluation parameters and functional status, daily living activities, balance, and ambulation levels.Materials and methods: This cross-sectional study included 45 patients with NMDs. The patients were divided into 3 groups, depending on the affected component of the motor unit (neuronopathy group, neuropathy group, and myopathy group). The laboratory and demographic data were recorded …
Determination Of The Embryotoxic Effects Of Propofol Injected Into Eggs On The Cerebellum And Spinal Cord Using Histologic Methods: An Animal Study, Murat İzgi̇, Emrah Sur
Determination Of The Embryotoxic Effects Of Propofol Injected Into Eggs On The Cerebellum And Spinal Cord Using Histologic Methods: An Animal Study, Murat İzgi̇, Emrah Sur
Turkish Journal of Medical Sciences
This study aims to determine the possible embryotoxic effects of propofol on the cerebellum and spinal cord using fertile chicken eggs. Materials and methods: A total of 430 fertile eggs were divided into 5 groups: control, saline, 2.5 mg.kg–1, 12.5 mg.kg–1, and 37.5 mg.kg–1 propofol. Injections were made immediately before incubation via the air chamber. On the 15th, 18th, and 21st day of incubation, 6 embryos from each group were evaluated. Serial paraffin sections taken from the cerebellum and spinal cord were stained with hematoxylin–eosin, Kluver–Barrera, toluidine blue, and periodic acid-Schiff ’s reaction. The outer granular layer and total cortex …
A Retrospective Study On The Clinical And Molecular Outcomes Of Calpainopathy In A Turkish Patient Cohort, İzem Olcay Şahi̇n, Emine Karataş, Mikail Demi̇r, Büşra Tan, Hüseyin Per, Yusuf Özkul, Munis Dündar
A Retrospective Study On The Clinical And Molecular Outcomes Of Calpainopathy In A Turkish Patient Cohort, İzem Olcay Şahi̇n, Emine Karataş, Mikail Demi̇r, Büşra Tan, Hüseyin Per, Yusuf Özkul, Munis Dündar
Turkish Journal of Medical Sciences
Calpainopathy, also known as limb-girdle muscular dystrophy recessive type 1, is a progressive muscle disorder that impacts the muscles around the hips and shoulders. The disease is caused by defects in the CAPN3 gene and can be inherited in both recessive and dominant forms. In this retrospective study, we aimed to evaluate the clinical and molecular results of our patients with calpainopathy and to examine the CAPN3 variants in Turkish and global populations.Materials and methods: Molecular analyses were performed using the next-generation sequencing (NGS) method. CAPN3 variants were identified through the examination of various databases.Results: In this retrospective study, the …
Effect Of Humic Acid On Oxidative Stress And Neuroprotection In Traumatic Spinal Cord Injury: An Experimental Study, Burak Kinali, Nail Özdemi̇r, Ali Karadağ, Özge Kaya Korkmaz, Ayşe Gülden Di̇ni̇z, Fatma Demet Arslan
Effect Of Humic Acid On Oxidative Stress And Neuroprotection In Traumatic Spinal Cord Injury: An Experimental Study, Burak Kinali, Nail Özdemi̇r, Ali Karadağ, Özge Kaya Korkmaz, Ayşe Gülden Di̇ni̇z, Fatma Demet Arslan
Turkish Journal of Medical Sciences
Traumatic spinal cord injury (TSCI) is an important health problem, especially in developing countries withadditional socioeconomic loss. Humic acid (HA) usually has antioxidant, antiinflammatory, blood circulating, and antiviral effects.Hence, it was aimed herein to show the effect of HA on neuroprotection in a TSCI model.Materials and method: A TSCI model was used, in which 24 Wistar albino rats were divided into 4 groups: control group: subjectedto only laminectomy; sham group: subjected to laminectomy + TSCI; HA 5 mg/kg group: subjected to laminectomy + TSCI +intraperitoneal (IP) injection of 5 mg/kg of HA; and HA 10 mg/kg group: subjected to laminectomy …
The Effect Of Erector Spinae Plane Block On Postoperative Extubation Time And Laboratory Parameters In Open Heart Surgery: A Retrospective Study, Feyza Çalişir, Yavuz Orak, Ömer Faruk Boran, Metin Ege, Mehmet Emin Karabeki̇roğlu, Hilal Bi̇radli, Adem Doğaner
The Effect Of Erector Spinae Plane Block On Postoperative Extubation Time And Laboratory Parameters In Open Heart Surgery: A Retrospective Study, Feyza Çalişir, Yavuz Orak, Ömer Faruk Boran, Metin Ege, Mehmet Emin Karabeki̇roğlu, Hilal Bi̇radli, Adem Doğaner
Turkish Journal of Medical Sciences
In open heart surgery, sternotomy causes inflammation in tissues, and inflammation causes postoperative pain. This study aims to examine the effects of bilateral erector spinae plane (ESP) blocks on postoperative extubation time and laboratory parameters in open heart surgery.Materials and methods: The study was managed using retrospective data from 85 patients who underwent open-heart surgery. Patients who received intravenous analgesia and were transferred to the intensive care unit with intubation were included in the study. Two groups were formed: those who received preoperative bilateral ESP block (ESB) and those nonblock (NB). Statistical significance was investigated between ESB and NB in …
Rehabilitation Therapy Versus Drug-Only Therapy In Patients With Multiple Sclerosis, Florin Mihai Marcu, Doriana Ciobanu, Ioan Cosmin Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Catalin Hreniuc, Dorina Ianc
Rehabilitation Therapy Versus Drug-Only Therapy In Patients With Multiple Sclerosis, Florin Mihai Marcu, Doriana Ciobanu, Ioan Cosmin Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Catalin Hreniuc, Dorina Ianc
Turkish Journal of Medical Sciences
The treatment for multiple sclerosis (MS) does not cure the disease, but it is intended to reduce the intensity, duration, and frequency of symptoms. Rehabilitation therapy (RT), including an individualized physical therapy program (PTP) and adapted occupational therapy (OT), has benefits in terms of aerobic capacity, muscle strength, coordination, and ability to perform activities of daily living (ADL). The primary objective of this study was to examine the efficacy of RT comprising PTP, OT, and drug treatment (DT) versus DT alone in patients with MS. Another objective was to highlight the importance of continuing the PT and OT at home, …
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Turkish Journal of Medical Sciences
Management of asymptomatic kidney stones is an ongoing debate with follow-up and treatment guidelines based on low-level evidence. Our aim was to evaluate current management of asymptomatic urinary stones.Materials and methods: A 70-question survey was designed in collaboration with European Association of Urology, Young Academic Urologists, Section of Uro-Technology and Section of Urolithiasis groups and distributed. Responders filled out hypothetical scenarios from 2 perspectives, either as treating physicians, or as patients themselves.Results: A total of 212 (40.01%) responses were obtained. Median responder age was 39 years. 75% of responders were interested in “urolithiasis”. 82.5% had never experienced a renal colic, …
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Turkish Journal of Medical Sciences
In this study, it was aimed to retrospectively compare the effect of greater occipital nerve (GON) block performed with ultrasonography using low (0.3%) and high (0.5%) concentrations of bupivacaine on pain scores and patient satisfaction in chronic migraine (CM).Materials and methods: The mean number of days with pain, the mean duration of pain in the attacks, and the highest numerical rating scale (NRS) scores recorded in the 1 month preblock and 1 and 3 months postblock of 80 patients (40 for Group 1, 0.3% bupivacaine; 40 for Group 2, 0.5% bupivacaine) who underwent ultrasonography-guided GON block were recorded from the …
The Right Ventricle Outflow Tract Systolic Function Could Predict The Severity Of The Cirrhosis, İbrahim Dönmez, Güray Can, Emrah Acar
The Right Ventricle Outflow Tract Systolic Function Could Predict The Severity Of The Cirrhosis, İbrahim Dönmez, Güray Can, Emrah Acar
Turkish Journal of Medical Sciences
The distinctive liver framework is converted into structurally abnormal nodules as a consequence of tissue fibrosis in cirrhosis. Cardiac dysfunction in cirrhosis was described, and the term “cirrhotic cardiomyopathy (CCM)” was coined to describe this syndrome. Recent research has shown that the contractile characteristics of the right ventricular outflow tract (RVOT) have a significant impact on right ventricular functions. The right ventricular outflow tract-systolic excursion is an important systolic function marker of RVOT (RVOT-SE). There has yet to be published research on RVOT function in cirrhotic patients. We looked at the relationship between cirrhosis severity and the RVOT-SE.Materials and methods: …
Dynamic Contrast-Enhanced Mammography And Breast Mri In The Diagnosis Of Breast Cancer And Detection Of Tumor Size, Muhammed Teki̇nhatun, Nuran Sabi̇r, Ergun Erdem, Sevda Yilmaz, Furkan Ufuk
Dynamic Contrast-Enhanced Mammography And Breast Mri In The Diagnosis Of Breast Cancer And Detection Of Tumor Size, Muhammed Teki̇nhatun, Nuran Sabi̇r, Ergun Erdem, Sevda Yilmaz, Furkan Ufuk
Turkish Journal of Medical Sciences
The aim of this study is to evaluate the performance of contrast-enhanced mammography (CEM) and dynamic breast MRI techniques for diagnosing breast lesions, assess the diagnostic accuracy of CEM’s using histopathological findings, and compare lesion size measurements obtained from both methods with pathological size.Materials and methods: This prospective study included 120 lesions, of which 70 were malignant, in 104 patients who underwent CEM and MRI within a week. Two radiologists independently evaluated the MR and CEM images in separate sessions, using the BI-RADS classification system. Additionally, the maximum sizes of lesion were measured. Diagnostic accuracy parameters and the receiver operating …
Minipuberty Period Of Children With Atopic Dermatitis Compared To Healthy Children, Serkan Bilge Koca, Hatice Eke Güngör, Murat Cansever
Minipuberty Period Of Children With Atopic Dermatitis Compared To Healthy Children, Serkan Bilge Koca, Hatice Eke Güngör, Murat Cansever
Turkish Journal of Medical Sciences
Atopic dermatitis (AD) is an inflammatory, pruritic, noncontagious, chronic relapsing skin disease. Skin barrierabnormalities, excessive T helper 2 activity, and immune dysregulation are held responsible. Androgens have a negative effect on theintegrity of the epidermal skin barrier, while estrogen has a positive effect. We aimed to investigate whether hormones make a differencebetween healthy children and children with AD during minipuberty.Materials and methods: A total of 96 infants (postnatal 4–13 weeks), 48 diagnosed with AD and 48 controls, were included. Each groupconsisted of 23 girls (47.9%) and 25 boys (52.1%). Anthropometric examinations and hormone measurements were compared.Results: The two groups, having …
The Otential Mechanism Of Treating Ic/Bps With Hyperbaric Oxygen By Reducing Vascular Endothelial Growth Inhibitor And Hypoxia-Inducible Factor-1Α, Jing Zhang, Jiarui Kang, Liyang Wu
The Otential Mechanism Of Treating Ic/Bps With Hyperbaric Oxygen By Reducing Vascular Endothelial Growth Inhibitor And Hypoxia-Inducible Factor-1Α, Jing Zhang, Jiarui Kang, Liyang Wu
Turkish Journal of Medical Sciences
To investigate the roles of vascular endothelial growth inhibitor (VEGI) and hypoxia-inducible factor-1α (HIF-1α) in the treatment of refractory interstitial cystitis/bladder pain syndrome (IC/BPS) with hyperbaric oxygen (HBO).Materials and methods: A total of 38 patients were included. They were assessed before and 6 months after HBO treatment. Three- day voiding diaries were recorded, and O’leary-Sant scores, visual analog scale (VAS) scores, quality of life (QoL) scores, pelvic pain, and urgency/frequency (PUF) scores were evaluated. Bladder capacity was assessed by cystoscopy. Bladder mucosa was collected for Western blot, qRT-PCR, and immunofluorescence staining to compare the expression of VEGI and HIF-1α before …
Evaluation Of Baseline F-18 Fdg Positron Emission Tomography In The Diagnosis And Assessment Of Giant Cell Arteritis, Burak İnce, Emine Göknur Işik, Zeynep Gözde Özkan, Yasemin Yalçinkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç
Evaluation Of Baseline F-18 Fdg Positron Emission Tomography In The Diagnosis And Assessment Of Giant Cell Arteritis, Burak İnce, Emine Göknur Işik, Zeynep Gözde Özkan, Yasemin Yalçinkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç
Turkish Journal of Medical Sciences
The aim of this study is to evaluate the baseline F18-FDG PET/CT findings of individuals diagnosed with giant cellarteritis (GCA) and to explore its association with clinical findings and classification criteria.Materials and methods: We analysed data from patients who underwent F18-FDG PET/CT scans to investigate large vessel (LV)involvement between 2010 and 2019. Only patients with a clinical diagnosis of GCA and at least 6 months of follow-up were included.We compared initial clinical features and laboratory findings based on the presence of LV vasculitis on PET/CT and the maximumstandard uptake value (SUVmax) of vascular territories.Results: Twenty-nine patients (median age at diagnosis: …
Survival Benefit Of Resin Cartridge Extracorporeal Blood Purification Therapy In Patients With Septic Shock, Serdar Efe, Pervin Hanci, Volkan İnal
Survival Benefit Of Resin Cartridge Extracorporeal Blood Purification Therapy In Patients With Septic Shock, Serdar Efe, Pervin Hanci, Volkan İnal
Turkish Journal of Medical Sciences
Extracorporeal blood purification (EBP) therapies have shown promise as potential rescue treatments for patientswith septic shock. However, precise evidence regarding their effectiveness is lacking. This case-control study aimed to evaluate the 28-day survival benefit of a resin cartridge-based EBP therapy compared to conventional therapies in patients with septic shock.Materials and methods: The study sample was collected retrospectively from the medical records of patients admitted to the intensivecare unit (ICU) between 2015 and 2020. The study included patients with septic shock aged ≥18 years who had ICU stays >96 h andexcluded those lost to follow-up by 28 days or readmitted. First, …
The Effect Of Video-Assisted Training On Upper Extremity Problems And Functions After Rotator Cuff Repair: A Randomized Controlled Trial, Canan Kanat, Gülay Altun Uğraş, Recep Ünal, Servet Can Dönmez, Bahar Taşdelen, Fehmi Volkan Öztuna
The Effect Of Video-Assisted Training On Upper Extremity Problems And Functions After Rotator Cuff Repair: A Randomized Controlled Trial, Canan Kanat, Gülay Altun Uğraş, Recep Ünal, Servet Can Dönmez, Bahar Taşdelen, Fehmi Volkan Öztuna
Turkish Journal of Medical Sciences
The shoulder is the most mobile joint in the body, and is frequently exposed to injuries. The applied surgical treatments, protection of the shoulder after surgery, care in the use of the shoulder in activities of daily living (ADLs) and gradual exercise programs are all vital to the recovery process. The present study investigates the effect of video-assisted training (VAT) on upper extremity complications and functions after rotator cuff repair (RCR).Materials and method: Included in this prospective, parallel two-armed, randomized controlled study were an experimental group (n: 24) that received VAT detailing early postoperative care for RCR and instructions on …
Predictive Values Of Mallampati Score, Tonsillar Size, And Bmi Z-Score In The Presence And Severity Of Obstructive Sleep Apnea In Pediatric Population, Ayşe Kaçar Bayram, Ahu Paketçi̇, Melek Nur Şahbaz, Sevde Daşdelen, Serkan Bilge Koca
Predictive Values Of Mallampati Score, Tonsillar Size, And Bmi Z-Score In The Presence And Severity Of Obstructive Sleep Apnea In Pediatric Population, Ayşe Kaçar Bayram, Ahu Paketçi̇, Melek Nur Şahbaz, Sevde Daşdelen, Serkan Bilge Koca
Turkish Journal of Medical Sciences
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder in children. Determination of riskfactors for the development of OSA is essential for early diagnosis and treatment of the disease and decreases the risk of negativeconsequences. This study aimed to investigate the predictive values of Mallampati score, tonsillar size, and BMI z-score in the presenceand severity of OSA in children.Materials and methods: This prospective cross-sectional study included 114 children with OSA symptoms. All children were assessedby BMI z-score, Mallampati score, and tonsillar size and underwent overnight polysomnography. They were consecutively selected andassigned to 4 groups as follows: Group 1 included …