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Articles 91 - 120 of 141
Full-Text Articles in Medicine and Health Sciences
The Effect Of Diphtheria Toxin On Nitric Oxideinduction From Raw264.7 Murine Macrophages, Cemalettin Aybay, Gülnur Tarhan, Turgut İmi̇r, Başak Kayhan
The Effect Of Diphtheria Toxin On Nitric Oxideinduction From Raw264.7 Murine Macrophages, Cemalettin Aybay, Gülnur Tarhan, Turgut İmi̇r, Başak Kayhan
Turkish Journal of Medical Sciences
In this study the effect of diphtheria toxin (DT) on nitric oxide (NO) production from RAW 264.7 murine macrophages was investigated. Griess reagent was used to determine NO production by measuring nitrite levels in the culture supernatants. Corynebacterium diphtheriae G12/6 strain-produced DT (Limes flocculation activity and immunodiffusion assays were positive) demonstrated a dose-dependent effect on RAW 264.7 macrophages to induce NO production. L-NAME, an L-arginine analogue, inhibited NO production from DT-stimulated RAW 264.7 macrophages. At the given concentrations of DT, lipopolysaccharide (LPS or endotoxin)-induced NO production from RAW 264.7 macrophages was also inhibited. RAW 264.7 macrophage cells, incubated with various …
Global Ischemia And Turn Preference; Acomparative Study Of The Effects Of Globalischemic Insult In Rats, Akçahan Gepdi̇remen, Cemal Gündoğdu, Sinan Sönmez, Dilek Sadeler, Halis Süleyman, Mehmet Emin Büyükokuroğlu
Global Ischemia And Turn Preference; Acomparative Study Of The Effects Of Globalischemic Insult In Rats, Akçahan Gepdi̇remen, Cemal Gündoğdu, Sinan Sönmez, Dilek Sadeler, Halis Süleyman, Mehmet Emin Büyükokuroğlu
Turkish Journal of Medical Sciences
We examined the effect of global cerebral ischemia (Two vessel occlusion plus systemic hypotension method) for 15 minutes on the hippocampal CA1 and CA3 neurones in rats, and compared with turn prefence scores. 14 of 27 animals were ambidexter while 9 had left and 4 had right turn preference. The left turns were significantly different from rights (t:2,26 df:26 p:0,032). Male rats prefered 62,73% and females 56,88% left turns. Forty-eight hours following the global cerebral ischemic insult, animals were sacrificed and brains were examined by using light microscope. Hippocampal neurones of the right hemisphere were survived more in males while …
Teratogenic Effects And The Role In The Etiologyof Atopic Diseases Of Erythrosine(Fd&C Red No.3), Onur K. Uysal, Erinç Aral
Teratogenic Effects And The Role In The Etiologyof Atopic Diseases Of Erythrosine(Fd&C Red No.3), Onur K. Uysal, Erinç Aral
Turkish Journal of Medical Sciences
Erythrosine (FD&C Red No.3, di sodium salt of 2,4,5,7-tetra-iodofluorescein); is used extensively as a colour additive in foods, drugs and cosmetics. Previous studies have shown that some of the food additives, depending on their long-term and short-term use, have potential carcinogenic, toxic and teratogenic effects. In Turkey this colourant has temporary permission of use until studies are completed about it. In addition food colours may cause allergic reactioins due to food intolerance. In our study 17 pregnant rats are divided into two groups: control and erythrosine group. 7 Wistar albino rats were administered 5 ml erythrosine (2mg/ml) by gavage at …
Renal Ultrastructural Alterations Followingadministration Of Diethylstilbestrol, Bilge Onarlioğlu, Yasemin Günay, İsmihan Göze, Emel Koptagel
Renal Ultrastructural Alterations Followingadministration Of Diethylstilbestrol, Bilge Onarlioğlu, Yasemin Günay, İsmihan Göze, Emel Koptagel
Turkish Journal of Medical Sciences
Diethylstilbestrol (DES), nonsteroid in structure, is an artificial estrogen derivative and is used as an anabolic agent. It is known that diethylstilbestrol causes genetic disorders and toxic effects leading up to carcinoma even in amounts below its residual levels. For this purpose, a dose of 60µm/kg/day of DES dissolved in 0,1 ml corn oil has been administered to rats by oral gavage for varying periods of 20, 50 and 100 days periods. Rat renal tissue samples, following routine electron microscopical procedure, have been examined by transmission electron microscopy. Following diethylstilbestrol administration, glomerular capilleries seemed dilated along with occasional basement membrane …
Incidence Of Listeria Spp. From Raw Milk In Sivas, Gülhan Vardar-Ünlü, Mehmet Ünlü, Mustafa Zahir Bakici
Incidence Of Listeria Spp. From Raw Milk In Sivas, Gülhan Vardar-Ünlü, Mehmet Ünlü, Mustafa Zahir Bakici
Turkish Journal of Medical Sciences
Raw milk samples obtained from the Foundation of Milk Industry, three private dairy companies and individual dairy farms in Sivas, were tested for the presence of Listeria species. A total of 100 raw milk samples were analysed by Food and Drug Administration (FDA) and two-stage enrichment techniques. Two-stage enrichment procedure was found to be more effective than FDA method in isolating Listeria species from raw milk. The overall incidence of Listeria species in raw milk was 6%. Listeria monocytogenes was found in 4% of the raw milk samples, while L. innocua was found in 2% of the samples. One sample …
The Inhibitory Effect Of Zinc On Imipenem Andmeropenem Susceptibility Of Pseudomonasaeruginosa, Selahattin Atmaca, Ramazan Çiçek, Kadri Gül
The Inhibitory Effect Of Zinc On Imipenem Andmeropenem Susceptibility Of Pseudomonasaeruginosa, Selahattin Atmaca, Ramazan Çiçek, Kadri Gül
Turkish Journal of Medical Sciences
In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem. Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.
Investigation Of The Inhibition Effects Of Someantibiotics On Human Erythrocytecarbonic Anhydrase Isozymes, T. Abdülkadir Çoban, Barbaros Nalbantoğlu, M. Yaşar Çi̇l, Hasan Özdemi̇r, Ö. İrfan Küfrevi̇oğlu
Investigation Of The Inhibition Effects Of Someantibiotics On Human Erythrocytecarbonic Anhydrase Isozymes, T. Abdülkadir Çoban, Barbaros Nalbantoğlu, M. Yaşar Çi̇l, Hasan Özdemi̇r, Ö. İrfan Küfrevi̇oğlu
Turkish Journal of Medical Sciences
In this study, the in vitro effects of some antibiotics on carbonic anhydrase (CA) isozymes have been investigated. Human erythrocyte CA-I and CA-II isozymes were separately purified by affinity chromatography. Inhibition effects of four different antibiotics on CA isozymes were determined by using the CO 2 -Hydratase method. I 50 values of antibiotics were obtained by drawing % Activity [Actibiotic] graphs. The obtained I 50 values of cefazolin sodium, cephradine, sulbactam/cefoperazone and chloramphenicol sodium succinate were 9, 16, 19 and 48 mM on CA-I and 6, 10, 15 and 17 mM on CA-II, respectively. Antibiotics dosages should be taken into …
Effect Of Acute And Regular Exercise Onantioxidative Enzymes, Tissue Damage Markersand Membran Lipid Peroxidation Of Erythrocytesin Sedentary Students, Recep Aslan, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Fahri Bayiroğlu, İsmail Meral
Effect Of Acute And Regular Exercise Onantioxidative Enzymes, Tissue Damage Markersand Membran Lipid Peroxidation Of Erythrocytesin Sedentary Students, Recep Aslan, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Fahri Bayiroğlu, İsmail Meral
Turkish Journal of Medical Sciences
15 healthy sedentary men, 19-25 years old an did not have any programmed physical activity, were studied. The subjects were asked to run submaximal 15-20 min every day for 5 weeks. Erythrocyte lipid peroxidation, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activities and glucose and uric acid levels were determined in blood samples which were taken before and immediately after acute exercise and after the end of 5-week training program. Malonaldialdehyde (MDA), sing of lipid peroxidation, creatin phosphokinase (CK), CK-MB, lactate dehydrigenase (LDH) concentrations increased (p
The Natural Menopause Age Of Women Inerzurum And Factors Influencing The Age Atmenopause, Nesrin Rei̇s, Türkân Pasi̇nli̇oğlu, Şenol Dane
The Natural Menopause Age Of Women Inerzurum And Factors Influencing The Age Atmenopause, Nesrin Rei̇s, Türkân Pasi̇nli̇oğlu, Şenol Dane
Turkish Journal of Medical Sciences
In this study the age at menopause and factors influencing age at menopause were investigated by a questionnaire in 282 women. The mean age of menopause was found to be 45.3 years and ranged from 35 to 54. Positive relationships were found between age at menopause and marital satus, body mass index, gravidity, parity, age at menarche, menstruation and menstruation bleeding period. Whereas negative relationships were found between age at menopause and smoking, age at first birth, abortion status and oral contraceptive use.
Paradoxical Therapy In Conversion Disorder, Ahmet Ataoğlu, Aytekin Sir, Mustafa Özkan
Paradoxical Therapy In Conversion Disorder, Ahmet Ataoğlu, Aytekin Sir, Mustafa Özkan
Turkish Journal of Medical Sciences
Paradoxical therapy consists of suggesting that the patient intentionally engages in the unwanted behaviour, such as performing complusive ritual or bringing on a conversion attack. In this study paradoxical intention (PI) was used with to half of the patients with conversion disorders, while the other half were treated with diazepam in order to examine the efficiency of the PI versus diazepam in conversion disorder. Patients treated with PI appeared to have a greater improvement rate for anxiety scores (z=2.43, p
The Effect Of Treatment Types On Plasma Levelsof Lipoproteins, Apolipoproteins And Lcat Intype Ii Diabetes Mellitus, Eser Vardareli̇, Belgin Efe, Fahrettin Akyüz, Mine İnal, Esat Erenoğlu
The Effect Of Treatment Types On Plasma Levelsof Lipoproteins, Apolipoproteins And Lcat Intype Ii Diabetes Mellitus, Eser Vardareli̇, Belgin Efe, Fahrettin Akyüz, Mine İnal, Esat Erenoğlu
Turkish Journal of Medical Sciences
In this studry 32 hyperglycemic patients with type II DM were treated with diet (7 patients), with gliclazide, an oral antidiabetic agent (10 patients), or with insulin (15 patients). The levels of liporoteins, apolipoprotein A and B and LCAT enzyme are measured before the therapy and 3 weeks after the achievement of glycemic control. Treatment types are compared with each other and with control group (10 normal persons) triglyseride (TG) and VLDL levels which were found to be high in all of the patients decreased in all groups to levels similar to control group. TC (total cholesterol), LDL, TC/HDL, LDL/HDL …
Effects Of Gliclazide And Insulin Therapy Onthromboxane B 2 And 6-Keta-Pgf 1\Alpha Levels Intype Ii Diabetic Patients, Ahmet Gökhan Özgen, Dilek Özmen, Füsun Hamulu, Metin Çeti̇n, Candeğer Yilmaz, Oya Bayindir
Effects Of Gliclazide And Insulin Therapy Onthromboxane B 2 And 6-Keta-Pgf 1\Alpha Levels Intype Ii Diabetic Patients, Ahmet Gökhan Özgen, Dilek Özmen, Füsun Hamulu, Metin Çeti̇n, Candeğer Yilmaz, Oya Bayindir
Turkish Journal of Medical Sciences
Diabetic patients show hemobiological abnormalities such as increased platelet adhesiveness, platelet hyperaggregability, decreased platelet half life, hemorheological abnormalities and altered fibrinolysis, perhaps contributing to a procoagulative state. Gliclazide, a novel sulfonylurea in routine clinical use, was thought to have effects on prostanoid release and platelet function. We studied thromboxane A 2 metabolite; serum thomboxane B 2 (TXB 2 ) and the prostacyclin metabolite, 6-keto-PGF 1\alpha to assess the efficacy of gliclazide on these parameters. Two groups of age and sex matched type II diabetics were examined in the study. There were 16 subjects in each group (F:M= 10/6). The study …
Plasma Fibronectin And Urineglycosaminoglycane Levels In Rheumatic Diseases, Nuriye Mete, Mahmut Mete, İ. Hakkı Öztürk, Leyla Çolpan
Plasma Fibronectin And Urineglycosaminoglycane Levels In Rheumatic Diseases, Nuriye Mete, Mahmut Mete, İ. Hakkı Öztürk, Leyla Çolpan
Turkish Journal of Medical Sciences
In this study, plasma fibronectin and urine glycosaminoglycane levels were determined spectrophotometrically in 20 Rheumatoid arthritis, 10 Ankilosing spondilites, 22 osteoarthrosis and 21 healthy control subjects. The mean levels of Fibronectin (\mug/ml) were 413.3±97 in patients with rheumatoid arthritis, 325.5±93.5 in ankilosing spondilites, 439.1±120.3 in osteoarthrosis and 302.2±60.1 in the control group. The ratio of urine glycosaminoglycan excretion to creatinine (g/mol) was 4.52±2.64 in patients with rheumatoid arthritis, 4.18±1.52 in patients with ankilosing spondilites, 2.72±1.19 in osteoarthrosis and 2.21±1.02 in the control group. Plasma Fibronectin levels were significantly higher in rheumatoid arthritis and osteoarthrosis when compared to the control group …
A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk
A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk
Turkish Journal of Medical Sciences
No abstract provided.
Mannoprotein Adhesin Of Candida Albicansgerm Tubes, Gülhan Vardar-Ünlü
Mannoprotein Adhesin Of Candida Albicansgerm Tubes, Gülhan Vardar-Ünlü
Turkish Journal of Medical Sciences
The production and detection of a mannoprotein adhesin (MPA) of the hyphal-form cells of C. albicans on plastic petri dishes was investigated. Using Concanavalin A-coated latex microspheres, the MPA was detected on the plastic surface on which C. albicans produced germ tubes. The adhesin was extracted using dithiothreitol and iodoacetamide. It did not inhibit the adhesion of the yeast-form C. albicans to buccal epithelial cells (BEC). This suggested that the MPA of the hyphal-form cells on the plastic was different from that on the yeast cells responsible for attachment to the BECs.
Identification Of Fibronectin Adhesins On Candidaalbicans, Gülhan Vardar-Ünlü
Identification Of Fibronectin Adhesins On Candidaalbicans, Gülhan Vardar-Ünlü
Turkish Journal of Medical Sciences
The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.
Controversy On Prophylactic Oophorectomy, Utku Özcan, Didem Akyol, Selma Oransay, Murat Ekin, Tayfun Güngör, Oya Gökmen
Controversy On Prophylactic Oophorectomy, Utku Özcan, Didem Akyol, Selma Oransay, Murat Ekin, Tayfun Güngör, Oya Gökmen
Turkish Journal of Medical Sciences
The merits of prophylactic oophorectomy at the time of hysterectomy have been debated for many years. The most compelling argument for prophylactic removal of the ovaries has always been the prevention of ovarian cancer (2). Prophylactic oophorectomy has advantages and disadvantages. The actual incidence of cancer in retained ovaries is difficult to estimate. The advantages of prophylactic oophorectomy include the prevention of ovarian cancer, the alleviation of symptoms from residual ovary syndrome and the elimination of the need for reoperation for adnexal disease (2). Disadvantages include surgical castration, which results in the need for hormone replacement, and changes in self-image …
Neuronal Differentiation In The Cerebral Cortexof The Rat: A Golgi-Cox Study, Necdet Demi̇r, Ramazan Demi̇r
Neuronal Differentiation In The Cerebral Cortexof The Rat: A Golgi-Cox Study, Necdet Demi̇r, Ramazan Demi̇r
Turkish Journal of Medical Sciences
The development of cerebral cortex neurons has been studied in different stages of pre- and postnatal periods of rats. In order to show the neuronal processes, the Golgi-Cox impregnation technique was used. The first neuronal process development was observed in the cranial and caudal poles of the cerebral cortex during the 15th prenatal day and continued spreading from the lateral regions and poles towards the dorsocentral regions of the hemispheres. The cells which showed the first impregnation in the cerebral cortex, were bipolar cells and their bodies were located in the deep regions of the hemisphere wall. Primitive multipolar cells, …
Age-Related Alterations In Superoxide Dismutaseand Catalase Activities In Rat Brain, Gülinnaz Alper, Eser Y. Sözmen, Lütfiye Kanit, Gülriz Mentes, Biltan Ersöz, Fatma Z. Kutay
Age-Related Alterations In Superoxide Dismutaseand Catalase Activities In Rat Brain, Gülinnaz Alper, Eser Y. Sözmen, Lütfiye Kanit, Gülriz Mentes, Biltan Ersöz, Fatma Z. Kutay
Turkish Journal of Medical Sciences
Active oxygen species have been proposed to be involved in the aging process of the brain, therefore alterations in the activities of enzymes involved in the defense system against free radicals and other active species could substantially influence the aging process. This study is planned to determine the brain superoxide dismutase (SOD) and catalase activities which defend the components of brain cells against active oxygen species, in order to evaluate whether they play a role in the aging process. The activities of SOD and catalase were measured in the cerebral cortex and cerebellum of Swiss male albino rats aged either …
Amino Acid Neurotransmitter Levels In Thecerebral Cortex Of Mice Receivingimipenem/Cilastatin -Lack Of Excitotoxicity In Thecentral Nervous System, Mete Akisü, Nilgün Kültürsay, Canan Çoker, Çiler Akisü, Meral Baka
Amino Acid Neurotransmitter Levels In Thecerebral Cortex Of Mice Receivingimipenem/Cilastatin -Lack Of Excitotoxicity In Thecentral Nervous System, Mete Akisü, Nilgün Kültürsay, Canan Çoker, Çiler Akisü, Meral Baka
Turkish Journal of Medical Sciences
Imipenem, a very potent carbapenem derivative beta-lactam antibiotic, has recently found a major place in the treatment of antibiotic-resistant nosocomial infections. However, a convulsive side effect is seen in 0.2-3 percent of patients. Although it is suggested that this effect is due to the inhibition of gamma-aminobutyric acid (GABA) mediated inhibitory transmission, no study has been reported so far showing its effect on the cerebral cortex free inhibitory and excitatory amino acid levels. Twenty-one male TO albino mice were divided into three equal groups and given therapeutic (40 mg/kg/day) or excessive (500 mg/kg/day) doses of Imipenem/cilastatine (I/C) or saline solution …
The Effects Of Shock Waves On The Rat Fetus, Orhan Yalçin, Lütfi Tahmaz, Zuhal Yumbul, İdris Bi̇lgi̇ç
The Effects Of Shock Waves On The Rat Fetus, Orhan Yalçin, Lütfi Tahmaz, Zuhal Yumbul, İdris Bi̇lgi̇ç
Turkish Journal of Medical Sciences
There is an ongoing controversy regarding shock wave lithotripsy (SWL) contraindicated during pregnancy (1, 2). While the effects of shock waves on a variety of cells in both clinical and experimental studies are well documented, their effects on the fetus remain to be clarified. In this study, we investigated the effects of SWL on the rat fetus. On the 8th, 11th, 14th and 17th days of pregnancy, 100, 250 or 500 shock waves were produced with a Multimed 2001 ELMED Systems Lithotriptor. In ongoing pregnancy, the effects of SWL on fetuses ranged from mild in early pregnancy to moderate and …
A Study On The Interparietal Bone In Man, Ferruh Yücel, Hulusi Eği̇lmez, Zehra Akgün
A Study On The Interparietal Bone In Man, Ferruh Yücel, Hulusi Eği̇lmez, Zehra Akgün
Turkish Journal of Medical Sciences
In the present study a total of 44 dry skulls and 500 skull films from the Sivas region of Turkey were examined to determine whether or not the interparietal bone was present. The incidence of interparietal bones was found to be 2.8 percent (15/544).
Anatomic And Hrct Demonstration Ofmidline Sternal Foramina, Zühre Aslı Aktan, Recep Savaş
Anatomic And Hrct Demonstration Ofmidline Sternal Foramina, Zühre Aslı Aktan, Recep Savaş
Turkish Journal of Medical Sciences
Midline sternal foramina are uncommon anomalies. Because of this, it is possible to mistakenly identify such a defect as defect as a gunshot wound or sternal disease by CT. In this study the frequency of midline sternal foramina in Turkish adults is investigated by high resolution computed tomography (HRCT) and visual inspection of sternal bones.
The Measurement Of Sweat Intensity Using Anew Technique, M. Tunaya Kalkan, Ertugrul H. Aydemi̇r, Yunus Karakoç, M. Ali Körpinar
The Measurement Of Sweat Intensity Using Anew Technique, M. Tunaya Kalkan, Ertugrul H. Aydemi̇r, Yunus Karakoç, M. Ali Körpinar
Turkish Journal of Medical Sciences
In this study, a new technique developed by us, called the "pad glove method" was used to measure sweat intensity in the palms of 15 patients with palmoplantar hyperhidrosis, and of 15 control subjects. Quantitative results in the hyperhidrosis group 2.1861±0.0836 grams/hour for the right hand and 2.2478±0.0961 grams/hour for the left hand, while in the control group were 0.3278±0.0419 grams/hour and 0.371±0.0501 grams/hours, respectively. Data were analyzed by Student's t test. The sweat intensities in the hyperhidrosis group were found to be significantly higher than in the control group in both hands (p
Lipid Peroxidation And Lipid Metabolism Inpostmenopausal Women, Banu Önvural, Hülya Öztüre, Ata Önvural, Meral Fadiloğlu
Lipid Peroxidation And Lipid Metabolism Inpostmenopausal Women, Banu Önvural, Hülya Öztüre, Ata Önvural, Meral Fadiloğlu
Turkish Journal of Medical Sciences
The aims of this study were to determine the degree of lipid peroxidation in the sera of postmenopausal women and compare this with the lipid peroxidation of a premenopausal group, and to see if there was any correlation between lipid parameters and lipid peroxidation within the groups. We assayed the lipid profiles and malondialdehyde (MDA), a marker for lipid peroxidation, in a postmenopausal group (n=57, mean age=49.4±6.6), an age-matched male group (n=21, mean age=48.5±6.7) and a control group (n=31, mean age=27.7±5.2). MDA was measured as thiobarbituric acid reactive substances (TBARS) using a modified version of Yagi's method. MDA was significantly …
Plasma Antioxidant Status And Nitrate Levels Inpatients With Hypertension Andcoronary Heart Disease, Bülent Sözmen, Cahit Kazaz, Dilek Taskiran, Leyla Aslan, Akan Akyol, Eser Yıldırım Sözmen
Plasma Antioxidant Status And Nitrate Levels Inpatients With Hypertension Andcoronary Heart Disease, Bülent Sözmen, Cahit Kazaz, Dilek Taskiran, Leyla Aslan, Akan Akyol, Eser Yıldırım Sözmen
Turkish Journal of Medical Sciences
In this study, we investigated first; the possible involvement of nitric oxide and antioxidant enzyme level in the pathogenesis of essential hypertension and second we investigated serum nitrite-nitrate and antioxidant enzyme activities and lipid profiles (total, HDL and LDL cholesterol, trygliceride) to determine the relationship between these parameters in atherosclerosis. 13 patients with coronary heart disease, 18 patients with essential hypertension and 16 age-matched health subjects were taken into this study. Plasma nitrite, nitrate levels were measured by Griess reaction, erythrocyter superoxide dismutase and catalase activities were determined by the methods of Misra&Fridovich and Aebi, respectively. Serum lipid analysis were …
The Role Of Ultrafiltration Therapy On Bloodpressure Of Hypertensive Chronic Hemodialysischildren, Caner Kabasakal, Sevgi Mi̇r, Ferah Sönmez, Nermin Beti̇n, Alpan Cura, Ruhi Özyürek
The Role Of Ultrafiltration Therapy On Bloodpressure Of Hypertensive Chronic Hemodialysischildren, Caner Kabasakal, Sevgi Mi̇r, Ferah Sönmez, Nermin Beti̇n, Alpan Cura, Ruhi Özyürek
Turkish Journal of Medical Sciences
Hypervolemia is supposed to be the principal factor in hypertension in chronic hemodialysis adults. In this study, the role of intensive ultrafiltration (UF) treatment to reduce hypertension due to hypervolemia in hemodialysis children was investigated. The inferior vena cava (IVC) was also evaluated as an index of UF therapy. Twenty-three hemodialysis children with the mean age 10.6±3.1 years were classified due to their blood pressure status. IVC measurements were performed with 2-D echocardiography and inferior vena cava index (IVCI) was calculated as diameter of inferior vena cava (mm)/ body surface area (m 2 ). UF therapy was applied to each …
Medullary Thyroid Carcinoma: Review Of27 Cases, Yasemin Onaran, Harika Oguz, Tarık Terzi̇oğlu, Serdar Tezelman
Medullary Thyroid Carcinoma: Review Of27 Cases, Yasemin Onaran, Harika Oguz, Tarık Terzi̇oğlu, Serdar Tezelman
Turkish Journal of Medical Sciences
Medullary thyroid carcinoma (MTC) may present in various clinical forms, either sporadic or a counterpart of hereditary endocrine disorders. The appropriate surgical procedure for MTC is total thyroidectomy combined with central neck clearance. The aim of this study was to document the initial clinical presentation, surgical treatment and clinical course of MTC in 27 patients. Thirteen (48.1%) cases were diagnosed as hereditary, either MEN 2a(7/27, 25.9%) or 2b syndrome (1/27, 3.7%) or familial non-MEN MTC (5/27, 18.5%), and fourteen cases were diagnosed as sporadic. Eighteen primary thyroid operations and twelve reoperative surgical procedures were performed on 24 patients. Eleven of …
Determination Of Ph, Fibronectin, Cholesterol,Lactate Dehydrogenase And Sialic Acid In Thedifferentiation Of Nonmalignant Andmalignant Ascites, Hülya Aksoy, Ahmet Kiziltunç, Yilmaz Aksoy, Naciye Kurtul, Ebubekir Bakan
Determination Of Ph, Fibronectin, Cholesterol,Lactate Dehydrogenase And Sialic Acid In Thedifferentiation Of Nonmalignant Andmalignant Ascites, Hülya Aksoy, Ahmet Kiziltunç, Yilmaz Aksoy, Naciye Kurtul, Ebubekir Bakan
Turkish Journal of Medical Sciences
Ascites, being an accumulation of excess fluid within the peritoneal cavity, is most frequently encountered in patients with cirrhosis or certain other diseases such as congestive cardiac failure, peritoneal tuberculosis and some primary or secondary peritoneal tumours. This study included 17 patients (5 females, 12 males) with malignant ascites (MA) and 23 patients (13 females, 10 males) with nonmalignant ascites (NMA). We aimed to determinet the values for total sialic acid (SA), pH, cholesterol, fibronectin, total protein concentrations and lactate dehydrogenase (LDH) activity in ascitic fluid for the differential diagnosis of ascites. While total SA, fibronectin, cholesterol, LDH and total …
Bone Marrow Involment And Myelofibrosis In Hudgkin's Disase, Sare Kabukçuoğlu, Ülkü Öner, Zeki Üstüner, Serap Işiksoy, Emine Dündar, Nilüfer Tel
Bone Marrow Involment And Myelofibrosis In Hudgkin's Disase, Sare Kabukçuoğlu, Ülkü Öner, Zeki Üstüner, Serap Işiksoy, Emine Dündar, Nilüfer Tel
Turkish Journal of Medical Sciences
The importance of bone marrow biopsy in Hudgkin's Disase is well known. The incidence of bone marrow involvement in Hudgkin's Disase varies from 2% to 29%. The presence of myelofibrosis is not sufficent evidence for a definitive diagnosis of bone marrow involment. Patients having myelofibrosis as a first symptom without pripherallympadenopathy must be distinguished from patients with idiopathic myelofibrosis. In this study, we examined the frequency of bone marrow involvement and the degree of myelofibrosis in Hudgkin's Disase. We found the incidence of bone marrow involvement to be 5.6%, and that of myelofibrosis to be 31.6%. The high incidence of …