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Full-Text Articles in Medicine and Health Sciences

Nicotine Dependence In Medical Students And Physicians In The Lakes Region, Rezan Demi̇ralay Jan 2003

Nicotine Dependence In Medical Students And Physicians In The Lakes Region, Rezan Demi̇ralay

Turkish Journal of Medical Sciences

This study was carried out to evaluate the level of physical nicotine dependence in medical students and physicians working in the Lakes region, Turkey. The standardized Fagerström test of nicotine dependence questionnaire was given to 135 physicians and 61 medical students who smoked daily. The rate of daily smoking was 28.4% in medical students and 33.7% in physicians. Average Fagerström test for nicotine dependence scores were 3.98 ± 2.69 for medical students, 3.69 ± 3.05 for general practitioners, 3.06 ± 2.23 for research assistants and 3.34 ± 2.88 for specialist physicians. Of the medical students, 15 (24.6%) indicated high nicotine …


Paraplegia Due To Extramedullary Hematopoiesis In The Thalassemia Intermedia, Şule Peker, Mehmet Çelebi̇soy, İsmai̇l Akkol, Hamdi̇ Bezi̇rci̇oğlu Jan 2003

Paraplegia Due To Extramedullary Hematopoiesis In The Thalassemia Intermedia, Şule Peker, Mehmet Çelebi̇soy, İsmai̇l Akkol, Hamdi̇ Bezi̇rci̇oğlu

Turkish Journal of Medical Sciences

ER^1, Mehmet ÇELEBİSOY^1, İsmail AKKOL^2, Hamdi BEZİRCİOĞLU^2 ^1Atatürk Education and Research Hospital Second Neurology Clinic, İzmir - Turkey ^2Atatürk Education and Research Hospital Neurosurgery Clinic, İzmir - Turkey


A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş Jan 2003

A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş

Turkish Journal of Medical Sciences

Overexpression of erbB-2 protein is a marker of clinically aggressive behavior in breast cancer patients. In general erbB-2 status is reported on a scale from negative to 3+, depending on staining intensity, if more than 10% of the tumor cells are stained. However, the original definition does not take into account the percentage of stained cells in detail, since all samples score in the same way if they are above the cut-off, established at 10%. In this study, we evaluated the erB-B2 overexpression by immunohistochemistry in 169 patients and evaluated any correlation with the other well known prognostic parameters. We …


The Serum Levels Of Il-1\Beta, Il-6, Il-8 And Tnf-\Alpha In Nonalcoholic Fatty Liver, İlyas Tuncer, Hanefi̇ Özbek, Cevat Topal, İsmai̇l Uygan Jan 2003

The Serum Levels Of Il-1\Beta, Il-6, Il-8 And Tnf-\Alpha In Nonalcoholic Fatty Liver, İlyas Tuncer, Hanefi̇ Özbek, Cevat Topal, İsmai̇l Uygan

Turkish Journal of Medical Sciences

Nonalcoholic fatty liver (NAFL) has an extensive clinical spectrum ranging from simple fatty liver to steatohepatitis and cirrhosis. Its pathogenesis is multifactorial. The aim of our study was to measure the serum levels of some cytokines (IL-1\beta, IL-6, IL-8 and TNF-\alpha), which are thought to play a role in the pathogenesis of NAFL. Thirty subjects (18 males, 12 females) with clinical and laboratory features of hepatosteatosis were enrolled in the study as the patient group (group 1) and 30 healthy subjects (21 males, 9 females) served as controls (group 2). The levels of hepatic transaminases, gamma-glutamyltransferase, alkaline phosphatase, total cholesterol, …


Atophic Rhinitis : A Case Report, Ayli̇n Yücel, Orhan Aktepe, Fatma Aktepe, Fevzi̇ Sefa Dereköy Jan 2003

Atophic Rhinitis : A Case Report, Ayli̇n Yücel, Orhan Aktepe, Fatma Aktepe, Fevzi̇ Sefa Dereköy

Turkish Journal of Medical Sciences

CEL^1, Orhan AKTEPE^2, Fatma AKTEPE^3, Fevzi Sefa DEREKOY^4 ^1Department of Radiology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^2Department of Microbiology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^3Department of Pathology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^4Department of Otolaryngology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey


Haemophilus Parainfluenzae Endocarditis, Emi̇ne Alp, Orhan Yildiz, Bi̇lgehan Aygen, Bülent Sümerkan Jan 2003

Haemophilus Parainfluenzae Endocarditis, Emi̇ne Alp, Orhan Yildiz, Bi̇lgehan Aygen, Bülent Sümerkan

Turkish Journal of Medical Sciences

No abstract provided.


Effect Of Edta On The Susceptibility Of Pseudomonas Aeruginosa To Imipenem, Ceftazidime And Cefepime In Mueller-Hinton Agar, Nezahat Akpolat, Tuncer Özeki̇nci̇, Gülseren Aktar, Özge Karaşahi̇n, Adnan Suay Jan 2003

Effect Of Edta On The Susceptibility Of Pseudomonas Aeruginosa To Imipenem, Ceftazidime And Cefepime In Mueller-Hinton Agar, Nezahat Akpolat, Tuncer Özeki̇nci̇, Gülseren Aktar, Özge Karaşahi̇n, Adnan Suay

Turkish Journal of Medical Sciences

No abstract provided.


Antimicrobial Activity And Characteristics Of Bacteriocins Produced By Vaginal Lactobacilli, Şengül Alpay Karaoğlu, Faruk Aydi̇n, S. Sirri Kiliç, Ali̇ O. Kiliç Jan 2003

Antimicrobial Activity And Characteristics Of Bacteriocins Produced By Vaginal Lactobacilli, Şengül Alpay Karaoğlu, Faruk Aydi̇n, S. Sirri Kiliç, Ali̇ O. Kiliç

Turkish Journal of Medical Sciences

The aim of this study is to test the production of bacteriocin in vaginal Lactobacilli and determining the characterization and antibacterial activity of this bacteriocin. For this reason 100 Lactobacillus strains were isolated and identified from vaginal swab samples of 75 women who attended obstetric and gynecology clinics. It was determined that six of 100 Lactobacillus strains produced bacteriocin. The antibacterial activity of bacteriocins was examined and found to be effective on vaginal L. gasseri, L. acidophilus, Gardnerella vaginalis ATCC 14018 and Pseudomonas aeroginosa ATCC 10145. We also found that bacteriocins were sensitive to proteinase enzymes and alkalinity, but resistant …


Quantification Of The Fli1 Gene Expression By Real-Time Quantitative Rt-Pcr, Hakan Savli, Sema Sirma, Uğur Özbek Jan 2003

Quantification Of The Fli1 Gene Expression By Real-Time Quantitative Rt-Pcr, Hakan Savli, Sema Sirma, Uğur Özbek

Turkish Journal of Medical Sciences

In this study, quantification levels were investigated to define alterations in the expression of the FLI1 gene on acute promyelocytic leukemia (APL), which is characterized by a reciprocal t(15,17) translocation of fusing the PML gene to the retinoic acid receptor alpha (RAR alpha) gene. The FLI1 gene plays an important role in several signal transduction pathways, and is involved in the normal regulation of myeloid hematopoiesis and leukomogenesis. We used the real-time quantitative RT-PCR (LightCycler) with SYBR Green I dye method for the labeling and analysis of the quantification of FLI1 gene RT-PCR products. Ribosomal protein S9 (RPS9) was used …


Suicide In The Province Of Eskişehir, Turkey: The Approach Of Forensic Medicine, Yasemi̇n Günay Balci, Emre Albek Jan 2003

Suicide In The Province Of Eskişehir, Turkey: The Approach Of Forensic Medicine, Yasemi̇n Günay Balci, Emre Albek

Turkish Journal of Medical Sciences

In the present study, a retrospective evaluation of suicides in the province of Eskişehir in 1997-1999 is made. Investigation reports of the Central Prosecutor's Office were obtained and the demographic data of the victims as well as the judicial criteria for the classification as "suicide" were evaluated. There were 94 cases of suicide and 65 of them (69.1%) involved males. Age distribution showed a predominance in the age group of 15-34 years. Suicide in males over 55 years of age occurred more frequently than in females (p < 0.05). Causes of death in suicides included hanging in 68.0% of cases, firearm wounding in 16.0%, jumping from heights in 7.4%, drug intake in 5.3%, railway suicides in 2.2% and butane inhalation in 1.1%; 79.8% of suicides occurred in residences. In 93.6% of the cases, scene investigation reports and drawings were obtainable, while photographs of the scene or of the victim were present in 53.2% of cases. A forensic medicine specialist's inquest had been performed in all cases whilst a medico-legal autopsy had been carried out in only 29.8% of cases. Death certificates were issued following an inquest and scene investigation in 66 cases. Medico-legal autopsies were performed in 73.3% of the cases of firearm wounding, 25.0% of the cases of hanging and 6.7% of suicides committed by other means. In conclusion, we emphasize the importance of a medico-legal autopsy in all suicide cases.


Are The Sequence And Level Of The Branches Of The Popliteal Artery Different In The Fetus Than In The Adult?: Two Fetuses With Popliteal Arterial Variation, Zeli̇ha Kurtoğlu, Mustafa Akteki̇n, Ahmet Hakan Öztürk, Cem Kara Jan 2003

Are The Sequence And Level Of The Branches Of The Popliteal Artery Different In The Fetus Than In The Adult?: Two Fetuses With Popliteal Arterial Variation, Zeli̇ha Kurtoğlu, Mustafa Akteki̇n, Ahmet Hakan Öztürk, Cem Kara

Turkish Journal of Medical Sciences

URTOĞLU Mustafa AKTEKİN Ahmet Hakan ÖZTÜRK Cem KARA Department of Anatomy Faculty of Medicine, Mersin University, Mersin - Turkey


Immunization Of Mice With Plasmid Dna Encoding Hepatitis B Virus Core Antigen (Hbcag), Yasemi̇n Bulut, Hakan Bulut, Mehmet Zi̇ya Doymaz Jan 2003

Immunization Of Mice With Plasmid Dna Encoding Hepatitis B Virus Core Antigen (Hbcag), Yasemi̇n Bulut, Hakan Bulut, Mehmet Zi̇ya Doymaz

Turkish Journal of Medical Sciences

The aim of this study was to investigate the antibody response following immunization with plasmid vector DNA containing the hepatitis B virus core antigen (HBcAg) gene of a hepatitis B virus (HBV) isolated from a patient in Turkey. A HBcAg gene fragment was cloned into a pcDNA 3 eukaryotic expression vector. After confirmation of the cloning of the HBcAg gene, the expressing vector based HBcAg was used in DNA immunization experiments. Four-to 6-week-old Balb/c mice were immunized with HBcAg expressing plasmids and the anti-HBcAg antibody responses of the mice were evaluated by enzyme immunoassay (EIA). The results of this study …


Problems In Urinary Iodine Determination Methods And An Automated Kinetic Assay As A Solution, Mustafa Gültepe, Ömer Özcan, Osman Meti̇n İpçi̇oğlu, Kadi̇r Avşar Jan 2003

Problems In Urinary Iodine Determination Methods And An Automated Kinetic Assay As A Solution, Mustafa Gültepe, Ömer Özcan, Osman Meti̇n İpçi̇oğlu, Kadi̇r Avşar

Turkish Journal of Medical Sciences

Accurate, fast and economical urinary iodine measurement is very important in diagnosing iodine deficiency disorders. The urinary iodine determination method using ammonium persulfate digestion based on the Sandell-Kolthoff reaction was optimized and modified to kinetic and automated assay. Ammonium persulfate digestion was performed at +95 ºC in a water-bath to ± 0.1 ºC precision. The performance of both the Sandell-Kolthoff reaction at 37 ºC and its kinetic measurement at 340 nm was tested in a random access automated analyzer. For method comparison, urinary iodine concentrations were measured using both the conventional chloric acid digestion method and the kinetic automated method …


Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür Jan 2003

Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür

Turkish Journal of Medical Sciences

Several factors may be responsible for the high prevalence of atherosclerosis in diabetes mellitus, including alterations in reverse cholesterol transport. In the present study, the activity of plasma lecithin:cholesterol acyltransferase (LCAT) and the cholesteryl ester transfer rate, and concentrations of lipids and lipoproteins were measured in 11 patients with insulin-dependent diabetes mellitus (type 1), 42 patients with noninsulin-dependent diabetes mellitus (type 2) and compared with those in age-matched control groups (Control I, n = 14; and Control II, n = 29, respectively). No statistically significant differences were observed in plasma total cholesterol, triglyceride, ester cholesterol or very low density lipoprotein …


Comparison Of Indirect Methods For Lactose Malabsorption, İsmai̇l Kurt, Mohammed Wael Abou Ghoush, Adnan Haşi̇mi̇, A. Muhi̇tti̇n Serdar, Türker Kutluay Jan 2003

Comparison Of Indirect Methods For Lactose Malabsorption, İsmai̇l Kurt, Mohammed Wael Abou Ghoush, Adnan Haşi̇mi̇, A. Muhi̇tti̇n Serdar, Türker Kutluay

Turkish Journal of Medical Sciences

Although direct determination of the lactase activity of the small intestinal mucosa is considered a "gold standard" for the diagnosis of hypolactasia leading to lactose malabsorption, less invasive and simpler indirect techniques like the "plasma glucose response test" and "breath hydrogen test" are preferred in daily practice to diagnose the disorder. The aim of this study was to compare the different indirect diagnostic methods for lactose malabsorption. The following tests were performed in 54 adults: plasma glucose response test, breath hydrogen test and urine galactose/creatinine ratio. The diagnostic variables were as follows: increased plasma glucose £ 20 mg/dl; increased exhalation …


Paratesticular Solitary Fibrous Tumour: Case Report And Review Of The Literature, Nusret Akpolat, Arslan Ardiçoğlu, Seyfetti̇n Yahşi̇, A.Rahmi̇ Onur Jan 2003

Paratesticular Solitary Fibrous Tumour: Case Report And Review Of The Literature, Nusret Akpolat, Arslan Ardiçoğlu, Seyfetti̇n Yahşi̇, A.Rahmi̇ Onur

Turkish Journal of Medical Sciences

KPOLAT^1 Arslan ARDIÇOĞLU^2 Seyfettin YAHŞİ^1 A. Rahmi ONUR^2 Departments of ^1Pathology and ^2Urology, Faculty of Medicine, Fırat University, Elazığ - TURKEY


Echinococcus Infestation Of Quadriceps Femoris Muscle Misdiagnosed As A Soft Tissue Tumor (A Case Report), Kaan Erler, Mahmut Kömürcü, M.Taner Özdemi̇r, Uğur Bariş Özkal, Mustafa Başbozkurt, Ömer Günhan Jan 2003

Echinococcus Infestation Of Quadriceps Femoris Muscle Misdiagnosed As A Soft Tissue Tumor (A Case Report), Kaan Erler, Mahmut Kömürcü, M.Taner Özdemi̇r, Uğur Bariş Özkal, Mustafa Başbozkurt, Ömer Günhan

Turkish Journal of Medical Sciences

ER^1 Mahmut KÖMÜRCÜ^1 M.Taner ÖZDEMİR^1 U. Barış ÖZKAL^1 Mustafa BAŞBOZKURT^1 Ömer GÜNHAN^2 Departments of ^1Orthopedics and Traumatology, ^2Pathology Gülhane Military Medical Academy, Etlik, Ankara - TURKEY


Peritoneal Defense Mechanisms, Toni̇ Hau Jan 2003

Peritoneal Defense Mechanisms, Toni̇ Hau

Turkish Journal of Medical Sciences

No abstract provided.


Bacterial Translocation After Partial Hepatic Resection Under Ischemia And Reperfusion In Rats: Incidence And Time Course, Abdulkadi̇r Bedi̇rli̇, Selma Gökahmetoğlu, Kadi̇r Can Küçük, Işin Soyuer, İlkay Güler, Ömer Şakrak Jan 2003

Bacterial Translocation After Partial Hepatic Resection Under Ischemia And Reperfusion In Rats: Incidence And Time Course, Abdulkadi̇r Bedi̇rli̇, Selma Gökahmetoğlu, Kadi̇r Can Küçük, Işin Soyuer, İlkay Güler, Ömer Şakrak

Turkish Journal of Medical Sciences

Infectious complications are major causes of morbidity and mortality following major hepatic resection. We investigated in rats the incidence and time course of bacterial translocation after partial hepatectomy during ischemia and reperfusion. Forty-eight male Wistar rats weighing 230 to 280 g were studied. Partial liver warm ischemia was performed for 15 min followed by reperfusion for 15 min. During a second 15 min of ischemia, 70% hepatectomy was performed. The animals were divided into six groups of eight animals each. Animals were sacrificed 8, 16, 24, 48, 72, and 120 h after the hepatectomy. At each time point blood was …


Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca Jan 2003

Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca

Turkish Journal of Medical Sciences

The objective of this study was to determine the morphological effects of chronic nitric oxide (NO) inhibition on the thoracic aorta of Wistar rats. Fifteen male Wistar Albino rats were divided into three groups. Group I rats (control group, n = 5) received tap water, group II rats (n = 5) recieved 100 mg/kg L-NAME (moderate NO inhibiton) and group III rats (n = 5) received 500 mg/kg L-NAME, in drinking water (severe NO inhibition) for 15 days. At the end of 15 days, the carotid arteries of the rats were cannulated and their blood pressure was measured. The rats …


Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu Jan 2003

Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu

Turkish Journal of Medical Sciences

The role of endogenous fibrinolysis in cerebral infarction has been investigated, but with conflicting results. In this study, variations of tissue-type plasminogen activator (t-PA) antigen concentrations over time after stroke were examined at the acute and subacute phases of ischemic stroke in a group of patients and in a control group. The relationships between t-PA levels and stroke severity, lesion volume and clinical status were also investigated. This study was carried out in 45 patients with acute ischemic stroke and 21 control subjects who had similar characteristics. Levels of t-PA mass concentration were measured via the ELISA, while Student's t, …


Carcinoma Of The Cecum: An Unusual Cause Of Fournier's Gangrene, Safvet Örs, Oğuz Ekmekci̇oğlu, Ati̇la Çoruh, Gali̇p K. Günay Jan 2003

Carcinoma Of The Cecum: An Unusual Cause Of Fournier's Gangrene, Safvet Örs, Oğuz Ekmekci̇oğlu, Ati̇la Çoruh, Gali̇p K. Günay

Turkish Journal of Medical Sciences

RS^1 Oğuz EKMEKCİOĞLU^2 Atila ÇORUH^1 Galip K. GÜNAY^1 Departments of ^1Plastic Surgery and ^2Urology, Faculty of Medicine, Erciyes University Kayseri - TURKEY


A Review Of Polyamines And Cancer, Wayne E. Criss Jan 2003

A Review Of Polyamines And Cancer, Wayne E. Criss

Turkish Journal of Medical Sciences

of Polyamines and Cancer Wayne E. CRISS Department of Biochemistry, Faculty of Medicine and Institute of Oncology, Hacettepe University, Ankara - Turkey


Ventilator Associated Pneumonia In Critically Ill Patients: Prevention And Treatment, Argyris Michalopoulos, Stefanos Geroulanos Jan 2003

Ventilator Associated Pneumonia In Critically Ill Patients: Prevention And Treatment, Argyris Michalopoulos, Stefanos Geroulanos

Turkish Journal of Medical Sciences

No abstract provided.


Effects Of Ramadan Fasting On Stroke, Selçuk Çomoğlu, Ahmet Temi̇zhan, Emel Peşi̇nci̇, İzzet Tandoğan, Şenay Özbakir Jan 2003

Effects Of Ramadan Fasting On Stroke, Selçuk Çomoğlu, Ahmet Temi̇zhan, Emel Peşi̇nci̇, İzzet Tandoğan, Şenay Özbakir

Turkish Journal of Medical Sciences

The effects of fasting on humans have not been adequately investigated. Ramadan fasting is a great opportunity for scientific research due to its peculiar nature. With this in mind, we conducted research on the effects of Ramadan on stroke, which is one of the most common causes of death in adults. Patients hospitalized solely for ischemic stroke and intracerebral hemorrhage were evaluated retrospectively. The ratio of these cases to other patients hospitalized in the neurology department was determined. The in-hospital clinical course and mortality rates of the patients with stroke were evaluated. Within the entire cohort, the most frequently encountered …


Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven Jan 2003

Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven

Turkish Journal of Medical Sciences

The protein p53 seems to be related to the suppression of cell proliferation. Positive tissues appear to have a higher proliferative activity than negative tissues. Mutation of the p53 tumour suppressor gene has been demonstrated in a large proportion of human head and neck tumours, although no formal evidence of functional aberration has been shown p53 may have importance during the early stage of malignancy. The aim of this study was to evaluate the role of the p53 tumour suppressor gene in the pathogenesis of odontogenic cysts. Expression of abnormal p53 protein is a widely recognised marker of malignancy. Expression …


Tru-Cut And Fine Needle Aspiration Biopsy Diagnosis Of Lesions Of The Jaws, Namik Kemal Ayhan, Cengi̇zhan Keski̇n, Kerem Dedeoğlu, Mehmet Yaltirik Jan 2003

Tru-Cut And Fine Needle Aspiration Biopsy Diagnosis Of Lesions Of The Jaws, Namik Kemal Ayhan, Cengi̇zhan Keski̇n, Kerem Dedeoğlu, Mehmet Yaltirik

Turkish Journal of Medical Sciences

Nowadays, modern biopsy techniques such as fine and wide needles are used instead of invasive biopsy techniques for examining malign and benign lesions. This study examines whether wide needle biopsy (Tru-cut) possesses advantages as an alternative method to open biopsy. This study was performed on 40 patients with suspicious intra-jaw lesions. An 18-gauge, three-piece biopsy device was used. All the samples were sent to the tumor pathology unit at the oncology institute for histopathologic and cytopathologic examination. Thirty-seven of the 40 samples were adequate for diagnosis and three inadequate were. When we considered the results of Tru-cut and fine needle …


The Ebmt Activity Survey On Hematopoietic Stem Cell Transplantation: A Novel Instrument For Quality Control, Alois Gratwohl, Helen Baldomero, Alvaro Urbano Ispizua Jan 2003

The Ebmt Activity Survey On Hematopoietic Stem Cell Transplantation: A Novel Instrument For Quality Control, Alois Gratwohl, Helen Baldomero, Alvaro Urbano Ispizua

Turkish Journal of Medical Sciences

The hematopoietic stem cell transplant activity survey of the European Group for Blood and Marrow Transplantation (EBMT) represents a novel modern tool in health care management. Introduced in 1990, it captures annual numbers of hematopoietic stem cell transplantation (HSCT) by indication, donor type and stem cell source from each individual European transplant team. Supplemented by demographical data and economic factors, team density and transplant rates can be calculated and the impact of economics on HSCT rates can be assessed. As documented in the present analysis, a total of 19,668 HSCT were performed in Europe in 2001 by 599 teams in …


Development Of A Diagnostic And Screening Elisa System For Measuring Tetanus Antitoxoid Levels, Cemaletti̇n Aybay, Resul Karakuş, Ahmet Gökhan Gündoğdu Jan 2003

Development Of A Diagnostic And Screening Elisa System For Measuring Tetanus Antitoxoid Levels, Cemaletti̇n Aybay, Resul Karakuş, Ahmet Gökhan Gündoğdu

Turkish Journal of Medical Sciences

Tetanus is a vaccine-preventable disease of global importance. When acquired it has a high mortality rate. Screenings of special subpopulations such as women of childbearing age provide important clues about tetanus vaccination coverage, and tools for mass protective measures, e.g, protective measures for neonatal tetanus. In addition to its reliability and sensitivity, the main advantage of a mass-screening tool should be its cost-effectiveness. We aimed to develop a cost-effective and sensitive enzyme-linked immunosorbent assay (ELISA) that can be used for diagnostic research as well as mass screening purposes for antitetanus antibodies. Our in-house antitetanus ELISA was validated and tested for …


Morphometric Evaluation Of The Foramen Magnum And Variations In Its Shape: A Study On Computerized Tomographic Images Of Normal Adults, Khalil Awadh Murshed, Aynur Emi̇ne Çi̇çekci̇başi, Işik Tuncer Jan 2003

Morphometric Evaluation Of The Foramen Magnum And Variations In Its Shape: A Study On Computerized Tomographic Images Of Normal Adults, Khalil Awadh Murshed, Aynur Emi̇ne Çi̇çekci̇başi, Işik Tuncer

Turkish Journal of Medical Sciences

The purpose of this study was to evaluate the radiological measurements of the foramen magnum (FM) and their relation to sex as well as to note variations in the shape of the FM. Cranial computerized tomographic images (CT) of 110 normal subjects (57 males - 53 females) between the ages of 18 and 80 years were examined in this study. The sagittal and transverse diameters of the FM were measured with a millimetric sliding caliper. Additionally, the area of the FM was also estimated. The statistical analysis for sex comparison was made using Student's t test. To determine the relationships …