Medicine and Health Sciences Commons^™

Surreptitious Ingestion Of Oral Anticoagulants, Thomas H. Greidanus, Ellis J. Van Slyck, Raymond W. Monto

Henry Ford Hospital Medical Journal

Hypoprothrombinemia secondary to surreptitious ingestion of coumarin or indanedione anticoagulants may be a difficult diagnosis for the unsuspecting physician. Four such case reports are presented. The disease should be suspected if the prothrombin time is markedly elevated and the individual is associated with the medical profession or has had previous treatment with oral anticoagulants. The diagnosis is confirmed by finding a deficiency in Factors II (prothrombin), VII, IX, and X and the presence of the coumarin or indanedione anticoagulant in the blood. The motive generally is that of gaining attention rather than committing suicide. Liver disease. Vitamin K deficiency states …

Double Contrast Arthrography Of The Knee, Peter C. Larowe, Robert S. Ormond, Edwin Guise

Henry Ford Hospital Medical Journal

Arthrography is a safe and relatively simple diagnostic procedure which provides an accurate and graphic preoperative means of defining pathology of the knee. In those cases where the expeditious evaluation and diagnosis of knee injury are of prime importance, ie, the athlete and industrial compensation case, arthrography provides a significant contribution. The clinical pathological features, salient anatomy and technic of study of internal derangements of the knee are discussed. Selected double contrast arthrograms illustrate normal and abnormal findings. Arthrotomies were performed in 20 of the 32 patients in this study with a positive arthrogram-arthrotomy correlation of 85%.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Immunologic Status Of Uremic Patients, Gerald A. Logrippo, C. E. Rupe, Hajime Hayashi, Dean Lesher

Henry Ford Hospital Medical Journal

The immunologic status of 25 uremic patients was studied with a battery of tests evaluating the humoral and cytological aspects of immunity. The individual's humoral immune status was evaluated as follows: quantitation of the three major serum immunoglobulins (IgG, IgA and IgM) expressed in mg/100 ml of serum and compared to established normal clinical standards (±2 SD/mean); qualitation of IgG and IgM evaluated by specific virus antibody titers and antitoxin values associated with IgG and by isoagglutinin tilers of the ABO blood groups associated with IgM. Immunoglobulin status is grouped into hyper- and hypo-immunoglobulin variations from normal and correlated with …

Cephalexin: In Vitro And In Vivo Studies, Frank Cox Jr., Edward L. Quinn, Bienvenido G. Gatmaitan, Nancy Peterson

Henry Ford Hospital Medical Journal

Cephalexin, a derivative of cephalosporin C, produces high serum and urine concentrations after oral administration. In addition, it shows good activity in vitro against most gram-positive and some gram-negative organisms. This study reports the in vitro susceptibility to cephalexin of a series of clinical isolates, the serum levels and urine concentrations in human volunteers and the results of its use in infections due to susceptible organisms. Results of in vitro susceptibility testing reveal that cephalexin was effective against most strains of the gram-positive organisms tested — group A streptococci, pneumococci, and staphylococci — although the MIC's are higher than those …

Hfh In The News

Henry Ford Hospital Medical Journal

No abstract provided.

Surgical Treatment Of Portal Hypertension: Review Of Henry Ford Hospital Experience, Joseph P. Elliott Jr., Kian H. Wong, Roger F. Smith

Henry Ford Hospital Medical Journal

Of 146 operations performed for the complications of portal hypertension in the Henry Ford Hospital between 1927 and August 31, 1969, 114 were portasystemic shunts. Operative mortality, sequelae and long term survival were closely related to the state of the patients' liver function and the urgency of operation.

Front Matter, Vol. 11 No. 2

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

End Matter, Vol. 11 No. 1

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

Adherence Of Men With Myocardial Infarction To Prescribed Exercise, Marsha Schwartz

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to find out if men with myocardial infarction followed exercise prescribed by the physician. The reasons the patients did or did not follow the exercise prescription were investigated.

An interview guide was used to gather the data for this exploratory study. The questions on the interview guide were designed to obtain information to compare the former exercise pattern of the patient to exercise after infarction. Adherence to the exercise prescription was also determined by the exercise reported in the interview. Fifteen male subjects who had myocardial infarction were interviewed in the hospital and after …

Front Matter, Vol. 11 No. 1

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

An In Vivo Perfusion Apparatus For Studies On Gingival Disease In The Albino Rat : Assessment By A Perfusion Of The Enzymes Collagenase And Hyaluronidase, James A. Smith

Loma Linda University Electronic Theses, Dissertations & Projects

This thesis describes an in vivo perfusion apparatus which can continuously deliver controlled quantities of solutions to localized, contralateral intraoral areas in albino rats. Three animals were per fused on the experimental area (the mesial sulcular area of the maxillary first molar) on one side with tap water and Trypan blue. Localization of the solution delivered and minimal histological changes due to the presence of the apparatus was demonstrated on these animals. Solutions of .5%, 1%, and 2% hyaluronidase and collagenase were perfused on the experimental areas of nine animals. When both enzymes were used, hyaluronidase always preceded collagenase in …

A Study To Demonstrate The Immediate Destination Of An Embolus Formed In The Lumen Of A Peripheral Venous Catheter, Rosemarie Morikone Emori

Loma Linda University Electronic Theses, Dissertations & Projects

This study was designed to show the immediate destination of an embolus formed in the lumen of an intravenous catheter placed in a peripheral vessel. The hypothesis stated that clots injected into a peripheral vessel will lodge in the lungs. A subhypothesis was that the clot may lodge anywhere along the circulatory pathway.

Indications of need for the study as shown by the review of literature were the following: (1) the complications resulting from the frequent use of intravenous polyethylene catheters, (2) experimental studies that showed that clots were formed around intravenous catheters, (3) the evidence that intravenous catheters predispose …

Ecological Planning Workshop Poster April, 1970, Ian Mcharg, Risd Archives

Ecology and Environment

Ecological Planning Workshop Poster by Ian McHarg. April 24, 1970, RISD Auditorium.

A Comparative In Vitro Metabolic Study Of Certain Pesticidal Phenyl N-Methyl-Carbamates, Larry A. Wheeler

Loma Linda University Electronic Theses, Dissertations & Projects

Two critical parameters in the evaluation of the toxicological hazards of the use of carbamate pesticides are: (1) a rapid, sensitive, and precise analytical method of identification of the carbamate and its metabolites; and (2) their metabolism. A method in this study was developed whereby various carbamates and their metabolites could be chromatographed in the gaseous phase. Also, a comparative in vitro study of 15,000 g liver supernatants from human, rat, and dog was performed. Additional tissues investigated for metabolic activity toward the carbamates, Zectran and Mesurol, were kidney (from the dog only) and various blood fractions (red blood cells, …

The Pharmacology Of Rodenticides, S. A. Peoples

Vertebrate Pest Conference Proceedings: 4th (1970)

The compounds used as rodenticides are tremendously varied in their chemical structure and mechanism of action. With a few exceptions, these agents are generally poisonous to all animals, including man, and a great deal of study has been directed to their toxicity in animals other than rodents. However, the development of new compounds as Norbormide and certain antifertility drugs which are highly selective in their action may justify the hope that the ideal rodenticide free of secondary toxic hazards will soon be available. Until this happy announcement is made, a review of the pharmacology of the older compounds is in …

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Hfh In The News

Henry Ford Hospital Medical Journal

No abstract provided.

Post-Therapeutic Thyroid Reserve: Thyroid Reserve In Euthyroid Patients After Ablative Therapy For Diffuse Toxic Goiter, J. Joseph Prendergast, J. Martin Miller

Henry Ford Hospital Medical Journal

Thyroid reserve was measured in 41 patients who were euthyroid 5 to 15 years after therapy for diffuse toxic goiter. Twenty-one of them had been treated by 131I, 20 by surgery and 10 were normal controls. All had a PBI (protein bound iodine) and 3-hour thyroidal 131I uptake. The same parameters of function were measured again 24 hours after they were given 10 units of thyroid stimulating hormone (TSH) intramuscularly. Only two patients in each treatment group responded with normal elevation of both the PBI and 131I uptake. In 52% of the 131I-treated patients and in 55% of those surgically …

A New Biological Stain For Peripheral Blood And Bone Marrow Smears, A. R. Villanueva

Henry Ford Hospital Medical Journal

A new blood stain has been developed for the demonstration and differentiation of cell types in peripheral blood or marrow smears, parasites in blood, and tissue impression preparations. It is available as a prebuffered powder which is dissolved in 100% reagent methanol. The method of staining is simple and rapid, with no precipitate. Overstaining is not likely to occur. The tinctorial patterns closely resemble some predecessors and, as the stain solution ages the staining quality improves. It is specific, stable, reproducible and resistant to fading.

Intestinal Lymphagiectasia With Normal Immunological Function: A Case Report, T. Madhavan, C. E. Rupe

Henry Ford Hospital Medical Journal

A patient is reported with histologically proven intestinal lymphangiectasia and protein losing enteropathy. The gastrointestinal protein loss and the effect of low fat diet have been demonstrated. The morphological abnormalities with radiological and lymphangiographic findings are discussed. Immunological studies are analyzed. These patients may have normal function both humoral and cellular, in spite of fairly advanced disease. Also the new hereto unreported association of Graves' Disease and intestinal lymphangiectasia has been brought out.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Total Gastrectomy For Carcinoma Of The Stomach, Thomas A. Fox Jr.

Henry Ford Hospital Medical Journal

The results of total gastrectomy in 47 patients with carcinoma of the stomach are reported. Extended total gastrectomy is recommended only if the growth cannot be removed by any other means. It should not be performed if the growth is not totally resectable. The operative mortality and postoperative results of total gastrectomy have improved to the extent that this operation for carcinoma of the stomach should be undertaken where indicated.

Quantitation Of Aortic Valvular Insufficiency Using Radioactive Tracers: An Experimental Study In Vitro, Frank J. Hildner, William R. Pierson, Bernard Weinstock, Ellet H. Drake, Robert S. Ormond

Henry Ford Hospital Medical Journal

A method has been developed in vitro for quantitation of aortic valvular insufficiency (Al) based on the use of ladioactive traceis lo genei-ate graphic recordings of the movement of blood out of the ventricle and back again. The regurgitant fraction of stroke volume (peirent of Al) is read from this recording. The method was evaluated in a mechanical heart model by comparing Al values read from the istope recordings and Al values determined volumetrically. The recordings gave excellent agreement with the volumetric results (Corr. Coeff. .9). These in vitro results are of such quality that clinical trials seem justified.

Echinococcosis Of The Liver: Report Of A Case, Roberto Benedetti, Joseph L. Ponka

Henry Ford Hospital Medical Journal

Echinococcosis of the liver is so rare in our practice that the case presented is the only one documented in the records of Henry Ford Hospital. The massive enlargement of the liver required surgical intervention. Marsupialization was the treatment of choice. In spite of post-operative complications, the patient made a satisfactory recovery.

Complications Of Pulmonary Angiography, D. T. Anbe, E. H. Drake

Henry Ford Hospital Medical Journal

Although data are available indicating the complication rates for routine cardiac catheterization, information has been lacking on the morbidity of pulmonary angiography in symptomatic patients. This retrospective study was undertaken to assess the "risks" of this procedure, by analyzing all cases undergoing pulmonary angiography from June 10, 1964. to December 31, 1967. Only two deaths were considered to be causally related to the pulmonary angiogram, a mortality rate of 1.4%. The overall complication rate was 15%. There was no correlation of the complications with the average age, or the concentration of the Hypaque used. There was a correlation between complications …

Serum Hepatitis At Henry Ford Hospital 1958-1967, K. S. Murthy, B. M. Schuman

Henry Ford Hospital Medical Journal

An analysis was done to determine the risk of hepatitis related to transfusions of whole blood or blood fractions. Of 180 cases indexed as serum hepatitis at Henry Ford Hospital, from 1958 to 1967, 148 had been transfused at this hospital. The overall incidence of hepatitis was 1.13 cases per 1,000 units transfused with a mortality rate of 7.4%.

Rubella: Current Status Of Immunization, E. L. Quinn, Frank Cox, Donald Romig

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Algal Growth And Decomposition: Effects On Water Quality, Edward G. Foree, John S. Tapp Jr.

KWRRI Research Reports

The chemical composition of algae grown in batch culture depends mainly on environmental conditions, nutrient availability, presence of predators, cell age, and species. The effects of nutrient availability and cell age on the composition of three unialgal cultures (algae + bacteria) and one hetergeneous culture (algae + bacteria + microscopic animals) were evaluated. The cultures were grown in batch culture under both nutrient-abundant and nutrient deficient conditions and the changes in compositions were observed. Luxurious uptake where nutrients are incorporated into cellular protoplasm at levels greater than those necessary for growth, and super-luxurious uptake, where some nutrients are stored rather …