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Full-Text Articles in Medicine and Health Sciences

Diet Quality As Assessed By The Healthy Eating Index-2020 Among Individuals Diagnosed With And Without Type 2 Diabetes, Minghao Zhou, Hairui Yu, Renee Underwood, Hongning Cai, Tung Sung Tseng, Susu Luo Dec 2026

Diet Quality As Assessed By The Healthy Eating Index-2020 Among Individuals Diagnosed With And Without Type 2 Diabetes, Minghao Zhou, Hairui Yu, Renee Underwood, Hongning Cai, Tung Sung Tseng, Susu Luo

School of Public Health Faculty Publications

Background: Dietary management is key to preventing and controlling type 2 diabetes mellitus (T2DM). However, few studies have examined differences in Healthy Eating Index (HEI-2020) scores and components among individuals with and without diagnosed T2DM. This study aimed to assess gender differences in HEI-2020 scores and its 13 components by T2DM status. Methods: Using National Health and Nutrition Examination Survey (NHANES) data from 2011 to 2018, this cross-sectional study analyzed 19,464 adults. Diagnosed T2DM was identified via self-report or diabetes medication use. Diet quality was assessed using the HEI-2020, scored from 0 to 100, with a higher HEI score indicates …


Nourishing Births: A Program Evaluation Proposal For Community-Based Nutrition Education, Food Access, And Garden Engagement Among Black Birthing People, Naa Deedei-Vera Hammond Dec 2026

Nourishing Births: A Program Evaluation Proposal For Community-Based Nutrition Education, Food Access, And Garden Engagement Among Black Birthing People, Naa Deedei-Vera Hammond

Master's Projects and Capstones

Black birthing people in the United States continue to experience unequal maternal health outcomes, shaped in part by racism and barriers to nutritious food, culturally relevant health education, and supportive community spaces. While prenatal nutrition education and food assistance programs can provide important resources, information alone cannot address the challenges many people face when trying to access healthy and affordable food during pregnancy. The Nourishing Births Initiative is a proposed community-based maternal health program designed to respond to these needs by bringing together prenatal nutrition education, help connecting to food resources, community gardening, and peer support for Black birthing people …


Surveillance And Comparative Genomics Of Bacteria From Hospital And Human Reservoirs, Emily E. Benedict Dec 2026

Surveillance And Comparative Genomics Of Bacteria From Hospital And Human Reservoirs, Emily E. Benedict

WUSM Theses and Dissertations – All Programs

Bacteria are diverse and adaptable and, consequently, present in a wide variety of environments. They are capable of growing under intense pressures, including those brought on by the human immune system and disinfection strategies. To survive these pressures, bacteria develop resistances. Antimicrobial resistance, which occurs when a microbe is no longer responsive to the antibiotic intended to control it, is one such adaptation that presents an especially serious threat, as it limits treatment options for infections caused by antimicrobial resistant microbes. Similarly, the ability of bacteria to survive in environments subjected to heavy disinfection efforts, such as intensive care units …


Multiomic And Single-Cell Analysis Of Tumors And Their Immune Microenvironment For Personalized Cancer Therapy, Kartik Singhal Dec 2026

Multiomic And Single-Cell Analysis Of Tumors And Their Immune Microenvironment For Personalized Cancer Therapy, Kartik Singhal

WUSM Theses and Dissertations – All Programs

Precision oncology aims to match cancer treatment to the biology of an individual patient’s tumor. However, tumors that share a diagnosis can differ in their molecular features, cellular composition, clinical course, and response to therapy, making it difficult to determine which treatment will benefit an individual patient. This dissertation integrates genomic, transcriptomic, and single-cell multiomic computational analysis to characterize tumors across their somatic alterations, transcriptional cell states, microenvironment, and the immune response they elicit.

The first study describes a rare case of donor-derived follicular lymphoma following kidney transplantation. Genomic profiling showed that the donor and recipient tumors shared 31 somatic …


In Adults Older Than 18 Years With Obesity Living In Massachusetts, Can Engaging In A Weight Loss Program Help Them Lose Weight After Insurance Stops Covering Their Weight Loss Medications?, Angel Nagawa Dec 2026

In Adults Older Than 18 Years With Obesity Living In Massachusetts, Can Engaging In A Weight Loss Program Help Them Lose Weight After Insurance Stops Covering Their Weight Loss Medications?, Angel Nagawa

Capstones

Executive summary

The Problem

Obesity rates continue to rise sharply across the United States. Weight loss medications have high compliance but face major insurance restrictions. Strict clinical criteria leave many patients without accessible treatment options.

The Proposed Solution

Launch structured, lifestyle-focused clinical weight loss programs. Provide an effective, accessible alternative to restricted pharmaceutical therapies.

Supporting Evidence

Evaluated data from three distinct randomized controlled trials. Findings confirm successful long-term weight management for program participants. Results prove effective control over serious obesity-related comorbidities.

Policy recommendation

Implement structured lifestyle programs as a primary, frontline intervention modality. Improve broad-scale patient health outcomes across clinical …


Exploring Burnout Among Ncaa Collegiate Athletes: The Impact Of Gender, Sport, Seasonal Demands, And Other Contributing Factors, Anneliese Wong Dec 2026

Exploring Burnout Among Ncaa Collegiate Athletes: The Impact Of Gender, Sport, Seasonal Demands, And Other Contributing Factors, Anneliese Wong

Undergraduate Honors Theses

The purpose of this study was to examine burnout among NCAA Division I student-athletes at one mid-sized University in the Rocky Mountains region of the United States and determine whether differences existed based on gender, sport type, competitive season stage, and burnout dimension. A quantitative, cross-sectional survey design was used and data was collected from 76 student-athletes across 11 varsity sports. Burnout was assessed using items adapted from the Athlete Burnout Questionnaire (ABQ; Raedeke & Smith, 2001), along with additional items assessing fatigue and seasonal experiences.

Descriptive results showed the student-athletes reported the highest mean level of physical burnout, followed …


Rna Chimeric Antigen Receptor (Car) T Cell Therapies For B Cell Mediated Autoimmune Diseases, Jayamuni Vasuki Vindiya Silva Dec 2026

Rna Chimeric Antigen Receptor (Car) T Cell Therapies For B Cell Mediated Autoimmune Diseases, Jayamuni Vasuki Vindiya Silva

Theses and Dissertations (ETD)

Systemic lupus erythematosus (SLE) is a chronic, multiorgan autoimmune disease caused by the breakdown of self-tolerance that leads to aberrant activation of B cells producing autoreactive antibodies. While traditional immunosuppressants. Glucocorticoids and biologics such as rituximab offer disease management, yet they fail to prevent flares and subsequent organ failures in severe SLE. In fact, increased doses of glucocorticoids are associated with irreversible organ damage. Newly emerged Chimeric antigen receptor (CAR) T-cell therapies have resulted in unprecedented clinical success with disease remissions and complete depletion of B cells, providing long-term disease remissions. However, autologous conventional CAR T therapies are constrained by …


In-Hospital Mortality Patterns And Readmissions In Patients With Chronic Obstructive Pulmonary Disease: An Analysis Of The Role Of Pulmonary Hypertension, Saad Afzal Khan, Trishna Parikh, Adishwar Rao, Akriti Agrawal, Aarohi Parikh, Sarah Shin, Maulin Patel, Kha Dinh, Bela Patel, Bindu Akkanti Dec 2026

In-Hospital Mortality Patterns And Readmissions In Patients With Chronic Obstructive Pulmonary Disease: An Analysis Of The Role Of Pulmonary Hypertension, Saad Afzal Khan, Trishna Parikh, Adishwar Rao, Akriti Agrawal, Aarohi Parikh, Sarah Shin, Maulin Patel, Kha Dinh, Bela Patel, Bindu Akkanti

Faculty, Staff and Student Publications

Chronic obstructive pulmonary disease (COPD) may be complicated by pulmonary hypertension (PH). We aimed to understand the impact of PH on in-hospital mortality and quantify the 30-day readmission rate among patients with COPD. For this cross-sectional study, we used the Nationwide Readmissions Database from 2017-2020 to identify adults ≥18 years with COPD. Patients were stratified according to PH diagnosis. Baseline characteristics between groups were compared using the Pearson chi-square test and two-sample t-test. Predictors of in-hospital mortality were determined using multivariate logistic regression analysis adjusted for demographics and confounders. The 30-day readmission rate and prevalence of PH subgroups by baseline …


Evaluating The Pulse Of Exercise Programs: Developing And Validating The Intervention Usability Scale For Exercise (Iuse) To Enhance Implementation And Adherence, Anne Inger Mørtvedt, Eva Ageberg, Steven Elmer, Kevin Trewartha, Erich Petushek Dec 2026

Evaluating The Pulse Of Exercise Programs: Developing And Validating The Intervention Usability Scale For Exercise (Iuse) To Enhance Implementation And Adherence, Anne Inger Mørtvedt, Eva Ageberg, Steven Elmer, Kevin Trewartha, Erich Petushek

Michigan Tech Publications

Background: Adherence to exercise interventions is often suboptimal, despite numerous studies documenting barriers and facilitators. Usability may be a critical yet underexplored determinant of adherence. This study aimed to develop and assess the psychometric properties of the Intervention Usability Scale for Exercise (IUSE). Methods: Item generation and content validation involved cognitive interviews and feedback from eight exercise intervention stakeholders and ten target users from the general public. Subsequently, 526 target users from University, Qualtrics and Prolific participant panels assessed exercise programs through an online survey. Dimensionality was assessed using Principal Component Analysis (PCA), Exploratory Factor Analysis (EFA), and bifactor models. …


Exploring Micronutrient Intake, Ultra-Processed Food Consumption, And Their Associations With Metabolic Syndrome And Food-Related Behaviors Among Adolescents In The United States, Oluyemisi Akinsola Dec 2026

Exploring Micronutrient Intake, Ultra-Processed Food Consumption, And Their Associations With Metabolic Syndrome And Food-Related Behaviors Among Adolescents In The United States, Oluyemisi Akinsola

All Graduate Theses and Dissertations, Fall 2023 to Present

Adolescence is a period of rapid growth and development during which good nutrition is especially important for long-term health. However, many adolescents in the United States consume large amounts of ultra-processed foods, including packaged snacks, sugary drinks, and fast food. This dissertation used nationally representative data from the National Health and Nutrition Examination Survey (NHANES) 2017–2020 to examine micronutrient intake, ultra-processed food consumption, food-related behaviors, and metabolic health among U.S. adolescents.

The first part of the study examined usual nutrient intake and micronutrient adequacy. Overall micronutrient adequacy was high at 96%. However, important dietary concerns remained. Many adolescents had low …


Development Of A Protein Mass Spectrometric Assay For The Characterization Of Colorectal Cancer Exosomes, Frank J. Reed Iv Nov 2026

Development Of A Protein Mass Spectrometric Assay For The Characterization Of Colorectal Cancer Exosomes, Frank J. Reed Iv

Science University Research Symposium (SURS)

Exosomes (sEV) carry proteins involved in intracellular communication and colorectal cancer (CRC) biology, but their morphologic overlap with non-vesicular extracellular particles (NVEPs), and other extracellular vesicles (EVs), including exomeres and supermeres, complicates proteomic characterization. This aim of this study is to develop mass spectrometric assays that evaluate sEV enrichment, purity, and distinguish sEV CRC-associated protein cargo from EV and NVEP CRC-associated protein cargo to better classify the role of sEVs in CRC biology.

Our lab previously analyzed conditioned media from DiFi, cystic clone (CC), and spikey clone (SC) CRC cell lines purified using dialysis, concentration, and electrophoresis enrichment (DCE) by …


Hydroponic Black Gram (Vigna Mungo) Fodder For Goats: Cultivation, Chemical Composition And Short-Term Feeding Acceptance, Nitira Anakkul, Nutthee Am-In, Theerawat Swangchan-Uthai Nov 2026

Hydroponic Black Gram (Vigna Mungo) Fodder For Goats: Cultivation, Chemical Composition And Short-Term Feeding Acceptance, Nitira Anakkul, Nutthee Am-In, Theerawat Swangchan-Uthai

The Thai Journal of Veterinary Medicine

Hydroponic black gram fodder (HBGF; Vigna mungo) may provide fresh supplemental forage for goats in land-restricted production systems. This descriptive study evaluated the seven-day growth characteristics and chemical composition of HBGF across indoor and outdoor conditions at seed densities of 1 and 2 kg/m², alongside short-term feeding responses. Indoor HBGF at 1 kg/m² was selected for a feeding study of two consecutive five-day periods in eight 50% Boer-crossbred does housed in two pens of four. At Day 7, indoor treatments yielded 5.33–8.50 kg/m² fresh biomass and 23.0–24.5 cm shoot length, compared with 2.10–3.94 kg/m² and 12.0–14.0 cm outdoors (ranges …


Joint Associations Of Physical Activity And Mindfulness Meditation With 12‑Month Self‑Rated Health Change Among U.S. Adults: A National Health Interview Survey Study, Yubing Wang Nov 2026

Joint Associations Of Physical Activity And Mindfulness Meditation With 12‑Month Self‑Rated Health Change Among U.S. Adults: A National Health Interview Survey Study, Yubing Wang

International Journal of Physical Activity and Health

Background: Lifestyle medicine emphasizes scalable behaviors that improve patient-centered health trajectories. Physical activity (PA) and mindfulness meditation are widely promoted, but nationally representative evidence on their joint engagement is limited. Methods:We analyzed adults from the 2012 and 2017 National Health Interview Survey (n=57,166). Guideline-level leisure-time PA and past-year mindfulness meditation formed four groups: Neither, PA only, Meditation only, and Both. The outcome was reporting better versus same or worse health relative to 12 months earlier. Survey-weighted models estimated adjusted probabilities, probability differences (PDs), and prevalence ratios (PRs). Results: Adjusted probabilities were 32.3% for Both, 27.7% for Meditation only, 22.4% …


Ybx1 Orchestrates Srebp2-Driven Cholesterol Metabolism To Confer Drug Resistance In Hepatocellular Carcinoma, Veerababu Nagati, Miguel Salazar, Swathi Tenugu, Yamile Abuchard, Ana Ayala Pazzi, Ricardo Pequeno Bracho, Dennis Kwabai, Manish K. Tripathi Nov 2026

Ybx1 Orchestrates Srebp2-Driven Cholesterol Metabolism To Confer Drug Resistance In Hepatocellular Carcinoma, Veerababu Nagati, Miguel Salazar, Swathi Tenugu, Yamile Abuchard, Ana Ayala Pazzi, Ricardo Pequeno Bracho, Dennis Kwabai, Manish K. Tripathi

Research Symposium

Background: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, with limited therapeutic options and poor prognosis. Sorafenib, a multikinase inhibitor, is the first-line treatment for advanced HCC; however, the rapid emergence of drug resistance significantly limits its clinical efficacy. Our preliminary data indicate that Y-box binding protein 1 (YBX1) contributes to sorafenib resistance by reprogramming cholesterol metabolism. Specifically, YBX1 upregulates sterol regulatory element-binding protein 2 (SREBP2), enhancing cholesterol biosynthesis and accumulation while downregulating the cholesterol efflux transporter ABCA1. This metabolic alteration stabilizes receptor tyrosine kinases (RTKs), promoting Akt/mTOR signaling and sustaining drug resistance, thereby unraveling the …


Effects Of Neurocognitive And Neuromuscular Exercises On Skill Performance And Injury Risk In Collegiate Volleyball Athletes, Matthew Albano, Rebecca Whitmer, Mallory S. Kobak, Michael J. Rebold Nov 2026

Effects Of Neurocognitive And Neuromuscular Exercises On Skill Performance And Injury Risk In Collegiate Volleyball Athletes, Matthew Albano, Rebecca Whitmer, Mallory S. Kobak, Michael J. Rebold

Journal for Sports Neuroscience

Athletic performance often requires rapid responses to unpredictable and environmentally reactive stimuli, highlighting the importance of neurocognitive function. Emerging evidence suggests that integrating neurocognitive and neuromuscular exercises may enhance skill performance and reduce injury risk during competition. These exercises, targeting reaction time, decision-making, audio and visual processing, memory, and dual-tasking may influence both injury incidence and biomechanics. This study evaluated the effects of neurocognitive and neuromuscular training across a collegiate men’s volleyball season, focusing on injury risk and skill performance outcomes (attack percentage and service error percentage). Athletes were randomly assigned to either a neurocognitive condition (NEURO) or …


Service-Learning Through A Community-Based Boxing Program For Persons With Parkinson’S Disease, Carrie Ellis, Jessica Watson Nov 2026

Service-Learning Through A Community-Based Boxing Program For Persons With Parkinson’S Disease, Carrie Ellis, Jessica Watson

Educational Practices in Kinesiology

The purpose of this manuscript is to discuss how a community-based boxing program can be implemented to engage students in service learning, while also providing a valuable service to an underserved population in the community. The intended audience for this activity is undergraduate exercise science or kinesiology students and graduate Doctor of Physical Therapy students. The program is delivered in person and requires an estimated time commitment of 75 minutes twice weekly. This activity is unique in that it combines the pedagogical benefits of service-learning for students with evidence-based treatment for Parkinson’s disease (PD). As PD is the second most …


The Buck Effect In Goats: A Review Of Neuroendocrine Mechanisms, Modulating Factors, And Applications In Reproductive Management, Nitira Anakkul, Sopita Suttikrai, Ratree Jintana, Theerawat Swangchan-Uthai Nov 2026

The Buck Effect In Goats: A Review Of Neuroendocrine Mechanisms, Modulating Factors, And Applications In Reproductive Management, Nitira Anakkul, Sopita Suttikrai, Ratree Jintana, Theerawat Swangchan-Uthai

The Thai Journal of Veterinary Medicine

The male effect (buck effect) is a sustainable, hormone-free biostimulation strategy in caprine reproduction, in which introducing sexually active bucks to seasonally anestrous does increases luteinizing hormone (LH) pulse frequency, thereby stimulating folliculogenesis and ovulation. This review provides a comprehensive synthesis of the sensory, neuroendocrine, breed-related, and management factors governing male biostimulation in goats (Capra hircus). Olfactory signals, including the identified primer pheromone 4-ethyloctanal, are perceived through the main and accessory olfactory systems and act together with visual, auditory, and tactile cues. These sensory inputs activate the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator probably through the medial amygdala …


The Role Of Social Media Influencers In Shaping Food Awareness And Dietary Behavior Among The Emirati Audience: A Field Study On Citizens Of Al Ain City, Laila Alkaabi, Huda Alremeithi, Reem Alnuaimi, Shamsa Almheiri, Amer Khaled Ahmad, Maram Manajrah Nov 2026

The Role Of Social Media Influencers In Shaping Food Awareness And Dietary Behavior Among The Emirati Audience: A Field Study On Citizens Of Al Ain City, Laila Alkaabi, Huda Alremeithi, Reem Alnuaimi, Shamsa Almheiri, Amer Khaled Ahmad, Maram Manajrah


This study aims to investigate the role of social media influencers in shaping food awareness and dietary behavior among the Emirati audience, drawing on media dependence theory and employing a public survey methodology through the administration of a questionnaire to a purposive sample of Emirati citizens in Al Ain City who follow influencers to obtain information on healthy nutrition. The findings revealed that more than (79.3%) of the sample members rely on social media influencers to obtain information on healthy nutrition at a moderate-to-high degree, with "the ease of rapid access to food-related information" emerging as the leading reason for …


Beyond The Screen: Dimensions Of Ecophilia In Snow White And The Seven Dwarfs (1937) And Children’S Awareness Of Them, Reham Refaat Mohammad Abdelaal Prof Nov 2026

Beyond The Screen: Dimensions Of Ecophilia In Snow White And The Seven Dwarfs (1937) And Children’S Awareness Of Them, Reham Refaat Mohammad Abdelaal Prof


This study aimed to explore the dimensions of Ecophilia in the film Snow White and the Seven Dwarfs and examine the extent to which children perceive these dimensions of love for nature and the environment. The study focused specifically on Biophilia (love of living beings) and Topophilia (love of a particular place or environment) from the perspective of ecocriticism, employing an interdisciplinary approach that integrates ecology, environmental animation, cinema, media studies, and environmental education.

The research was conducted on a sample of 100 boys and girls aged between 6 and 12 years, as children within this age group possess the …


Assessment Of Pletekan Leaf Extract (Ruellia Tuberosa L.) As An Antibacterial Feed Additive For Broiler Chickens (Gallus Gallus Domesticus L.) Infected With Salmonella Sp., Nuria Istiqomah, Poncojari Wahyono, Rury Eryna Putri, Abdulkadir Rahardjanto Nov 2026

Assessment Of Pletekan Leaf Extract (Ruellia Tuberosa L.) As An Antibacterial Feed Additive For Broiler Chickens (Gallus Gallus Domesticus L.) Infected With Salmonella Sp., Nuria Istiqomah, Poncojari Wahyono, Rury Eryna Putri, Abdulkadir Rahardjanto

Jurnal Ilmu Ternak Universitas Padjadjaran

The use of synthetic antibiotics as antibiotic growth promoters (AGPs) in broiler chickens raises concerns over antibiotic residues and bacterial resistance, necessitating safer natural alternatives. Ruellia tuberosa L. contains various secondary metabolites with potential antibacterial properties; however, its in vivo efficacy against Salmonella sp. remains poorly documented. This study aimed to analyze the phytochemical composition of R. tuberosa leaf extract and evaluate its antibacterial activity against Salmonella sp. in broiler chickens. A Completely Randomized Design (CRD) was employed with eight treatments: a positive control (tetracycline), a negative control (Tween-80), and six extract concentrations (125, 250, 375, 500, 625, and 1000 …


The Effect Of Tannin Powder Supplementation In The Ration On Hematological Profiles And Blood Urea Nitrogen Of Priangan Sheep, Najwa Hegyra Gumilar, Iman Hernaman, Diding Latipudin, Ghistavera Izvantika Nov 2026

The Effect Of Tannin Powder Supplementation In The Ration On Hematological Profiles And Blood Urea Nitrogen Of Priangan Sheep, Najwa Hegyra Gumilar, Iman Hernaman, Diding Latipudin, Ghistavera Izvantika

Jurnal Ilmu Ternak Universitas Padjadjaran

The use of dietary tannins as natural feed additives to regulate rumen protein degradation and improve nitrogen metabolism has been increasingly explored. Nevertheless, the evidence concerning the combined use of chestnut (Castanea sativa) and quebracho (Schinopsis lorentzii) tannin extracts in Priangan sheep is still limited. This study aimed to evaluate the effects of a commercial tannin powder containing these two plant extracts on Blood Urea Nitrogen (BUN) concentration and hematological profiles in Priangan sheep. Eighteen healthy male Priangan sheep with an initial average body weight of 19.64±2.51 kg were randomly allocated into three dietary treatments in …


Release Of Bound Steroid From The Androgen And Estrogen Receptors Is Induced By Ddt And Its Analogs, Matthew D. Rosales, Tahyra Soto, Jacqueline I. Goodship, Ahyssa R. Cruz, Isaac A. Rodriguez, Ventura Cuba Flores, Amanda Chavez, Monica P. Solis, Esmeralda Lopez, Frank B. Dean, Evangelia Kotsikorou Nov 2026

Release Of Bound Steroid From The Androgen And Estrogen Receptors Is Induced By Ddt And Its Analogs, Matthew D. Rosales, Tahyra Soto, Jacqueline I. Goodship, Ahyssa R. Cruz, Isaac A. Rodriguez, Ventura Cuba Flores, Amanda Chavez, Monica P. Solis, Esmeralda Lopez, Frank B. Dean, Evangelia Kotsikorou

School of Integrative Biological & Chemical Sciences Faculty Publications

The pesticide p,p'-DDT (DDT) and its analogs (p,p'-DDD, o,p'-DDD, and p,p'-DDE) inhibit the binding of dihydrotestosterone (DHT) to the androgen receptor (AR) and estradiol (E2) to the estrogen receptor (ERα) ligand-binding domains (LBDs), as previously reported. In this study, we introduce assays to measure the release of receptor-bound steroids. These compounds induced the release of DHT from the AR LBD and E2 from the ERα LBD. These findings suggest that DDT and its analogs may interact with a surface site on the LBD, thereby allosterically disrupting steroid binding. One potential site is binding function 3 (BF3). To explore this possibility, …


Implementation Of A Preventative Screen To Detect Heartworm Disease In Local Mosquito Populations, Ava Hurley, Emma Weissmeier, Lucy Corten, Jayden Ockert, Jackson Greenwold-Claiborne, Addison Levitz, Carson Mickey, Alexandra Bonner, Paul E. Richardson Oct 2026

Implementation Of A Preventative Screen To Detect Heartworm Disease In Local Mosquito Populations, Ava Hurley, Emma Weissmeier, Lucy Corten, Jayden Ockert, Jackson Greenwold-Claiborne, Addison Levitz, Carson Mickey, Alexandra Bonner, Paul E. Richardson

Journal of the South Carolina Academy of Science

Heartworm disease, caused by the parasite Dirofilaria immitis, affects thousands of mammalian pets across the nation annually and is increasingly spreading. Various mammalian pets including dogs, cats, ferrets, and horses are affected by the disease, and currently dogs are the only mammalian pets with an approved treatment. This study aims to implement a preventative approach to combating the disease by utilizing a PCR-based screen to detect D. immitis in mosquito populations. Five key objectives were established in this study: refine a preventative screen to detect heartworm DNA in mosquitoes, implement the preventative screen through partnerships with local animal shelters, …


Development Of Genomic Detection Techniques Of Aquatic Pathogens To Aid In Disaster Relief After Hurricanes, Ana Rose Johnson-Redmon, Abigail F. Turka, Rylie Masterson, Paul E. Richardson Oct 2026

Development Of Genomic Detection Techniques Of Aquatic Pathogens To Aid In Disaster Relief After Hurricanes, Ana Rose Johnson-Redmon, Abigail F. Turka, Rylie Masterson, Paul E. Richardson

Journal of the South Carolina Academy of Science

Extreme weather events such as hurricanes, tropical storms, and flooding can introduce microbial contaminants into freshwater systems through stormwater runoff, animal waste, and damaged or overwhelmed wastewater infrastructure. Rapid detection of waterborne pathogens is important for environmental monitoring and public health response, especially in coastal regions vulnerable to hurricane-related flooding. This study developed and refined a polymerase chain reaction (PCR)-based environmental DNA detection technique to identify aquatic pathogens in freshwater systems. Water samples were collected from four freshwater sites, including three man-made ponds and one drainage ditch, during the Fall 2025 and Spring 2026 semesters. Target organisms include Giardia, Cyclospora, …


Investigating The Prevalence Of Human Papilloma Virus In A College-Aged Sample Group And Its Link To Sexual Behaviors And Attitudes, Gabriela Lewczyk, Eva Pollak, Phoebe Stryker, Samantha Hickey, Emily Moyer, Katelyn Ambrose, Alexander Knight, Rahjai Thomas, Adriana Burk, Paul E. Richardson Oct 2026

Investigating The Prevalence Of Human Papilloma Virus In A College-Aged Sample Group And Its Link To Sexual Behaviors And Attitudes, Gabriela Lewczyk, Eva Pollak, Phoebe Stryker, Samantha Hickey, Emily Moyer, Katelyn Ambrose, Alexander Knight, Rahjai Thomas, Adriana Burk, Paul E. Richardson

Journal of the South Carolina Academy of Science

Human Papilloma Virus (HPV) is the most common sexually transmitted infection (STI) in the United States, infecting up to 75% of sexually active individuals, with a prevalence rising significantly around age nineteen for oral and genital infections. Because the virus infects epithelial cells and is transmitted primarily through skin-to-skin contact, it is found mainly in the cervix, oral cavity, and on/within ones’ skin. While most of the 200+ HPV subtypes are benign and tend to self-clear within six months to two years, twelve of these strains are classified as high-risk oncogenic strains that drive malignant progression. Furthermore, HPV is linked …


Development Of A Molecular Screen For Community-Based Hookworm Detection, Emma Weissmeier, Ava Hurley, Jackson Greenwold-Claiborne, Morgan Deeringer, Paul E. Richardson Oct 2026

Development Of A Molecular Screen For Community-Based Hookworm Detection, Emma Weissmeier, Ava Hurley, Jackson Greenwold-Claiborne, Morgan Deeringer, Paul E. Richardson

Journal of the South Carolina Academy of Science

Hookworm disease, caused by Ancylostoma duodenale and Necator americanus, is a soil-transmitted infection affecting over 700 million people worldwide. Transmission occurs through direct skin contact with contaminated soil, leading to health consequences including iron-deficiency anemia, malnutrition, and long-term developmental impacts. The CCU Disease Hunters program developed a PCR-based environmental screen to detect hookworm DNA in soil samples before transmission reaches human or animal hosts. Initiated in response to a request from All 4 Paws Animal Rescue, this project established protocols for soil collection, DNA extraction, and molecular identification of hookworm using the cytochrome c oxidase (COI) and cytochrome b (COB) …


A Philosophical Introduction To Elements And Relations: Aspects Of A Scientific Metaphysics, Martin Zwick Oct 2026

A Philosophical Introduction To Elements And Relations: Aspects Of A Scientific Metaphysics, Martin Zwick

Complex Systems Faculty Publications and Presentations

My book, Elements and Relations*, amplifies Bunge’s characterization of the systems project as the construction an “exact and scientific metaphysics” (ESM) different from and broader than the reductionist and physicalist ontology of conventional science. This paper discusses the scientific theories constituting this project and the central notion of “system” as a structure-function dyad, where “structure” is the system’s internal order and “function” is its participation in the external order of its environment. The paper also discusses the book’s proposal of ontology and ethics as a structure-function dyad for the systems field, an ontology of problems that exemplifies the ESM idea.


Laboratory Study Of A Waste Anesthetic Gas Mask Scavenging System To Reduce Airborne Pathogen Exposure For Health Care Workers In Post Anesthesia Care Units, Josh Horton, Trevor Lim, Andrew Kanach, John Moenning, James Mcglothlin, Bruce M. Applegate Sr. Oct 2026

Laboratory Study Of A Waste Anesthetic Gas Mask Scavenging System To Reduce Airborne Pathogen Exposure For Health Care Workers In Post Anesthesia Care Units, Josh Horton, Trevor Lim, Andrew Kanach, John Moenning, James Mcglothlin, Bruce M. Applegate Sr.

HCA Healthcare Journal of Medicine

Introduction

A scavenging oxygen mask system (SOMS) utilizing house vacuum has been demonstrated to significantly reduce exposure of post anesthesia care unit (PACU) health care workers (HCWs) to waste anesthetic gases (WAGs). Therefore, it was proposed that the same system could also be used to protect HCWs in the PACU by reducing Infectious Respiratory Particles (IRPs) spread from patients who may harbor airborne infective pathogens, such as Mycobacterium tuberculosis, certain strains of influenza, and SARS-CoV-2.

Methods

A life-like adult manikin head equipped with a bio-aerosol Collison nebulizer was set up to simulate patients exhausting pathogenic droplets. Further evaluation of …


The Role Of Local Protein Sources In Nutritious And Balanced Complementary Feeding For The Prevention Of Stunting In Infants Aged 6-24 Months, Kysara Aureldy Davonso Matualage, Leonardo Tedjaprasadja, Chy'as Diuranil Astrid Permataputri Oct 2026

The Role Of Local Protein Sources In Nutritious And Balanced Complementary Feeding For The Prevention Of Stunting In Infants Aged 6-24 Months, Kysara Aureldy Davonso Matualage, Leonardo Tedjaprasadja, Chy'as Diuranil Astrid Permataputri

Indonesian Journal of Public Health Nutrition (IJPHN)

Stunting remains a major public health problem in Indonesia, with prevalence rates still above national targets. The complementary feeding period (6–24 months) is a critical window for prevention, during which inadequate protein intake significantly contributes to impaired linear growth. Local animal protein sources offer an accessible and sustainable strategy to improve dietary quality. This study aims to review scientific evidence on the role of local animal protein sources in nutritionally balanced complementary feeding for the prevention of stunting in Indonesian infants aged 6–24 months. A literature review was conducted by systematically searching scientific databases for studies published between 2020 and …


Development And Nutritional Evaluation Of Plantain–Soy Composite Flour Blends As Complementary Foods For The Management Of Protein-Energy Malnutrition, Jelili A. Quadri Dr., Azeesat O. Adebiyi-Olabode Dr, Anifat B. Saka Mrs., Debbie M. Esekhade Miss Oct 2026

Development And Nutritional Evaluation Of Plantain–Soy Composite Flour Blends As Complementary Foods For The Management Of Protein-Energy Malnutrition, Jelili A. Quadri Dr., Azeesat O. Adebiyi-Olabode Dr, Anifat B. Saka Mrs., Debbie M. Esekhade Miss

Indonesian Journal of Public Health Nutrition (IJPHN)

Protein energy malnutrition (PEM) continues to be a critical problem in public health, especially in developing nations where sources of affordable nutrient-dense foods are unavailable. Plantain is one of the staple foods rich in carbohydrates but deficient in protein, while soybeans are protein-rich legumes. A blend of these local foods in composite flour will increase the nutritional value of plantain-based foods without compromising their sensory properties. The objective of this study was to formulate plantain-soy composite flour blends at various substitution rates and determine their composition and sensory characteristics. Unripe plantain and soybean were milled into flour and mixed in …