Medicine and Health Sciences Commons^™

Using Detection Dogs And Rspf Models To Assess Habitat Suitability For Bears In Greater Yellowstone, Jon P. Beckmann, Lisette P. Waits, Aimee Hurt, Alice Whitelaw, Scott Bergen

Western North American Naturalist

In the northern U.S. Rockies, including the Greater Yellowstone Ecosystem (GYE), connectivity is a concern because large carnivores have difficulties dispersing successfully between protected areas. One area of high conservation value because of its importance for connecting the GYE to wilderness areas of central Idaho is the Centennial Mountains and surrounding valleys (2500 km2) along the Idaho–Montana border just west of Yellowstone National Park. The current expansion of grizzly bears (Ursus arctos) and other large carnivore populations outside protected areas of Yellowstone National Park and Grand Teton National Park has placed a greater emphasis on potential linkage zones …

Β-Thujaplicin: A Soil Antifungal, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

Background: β-thujaplicin (β-Th), also known as hinokitiol, naturally occurs in cedar mulch, is found in personal care products and has in vitro antitumor activities. It is antibacterial and antifungal, but has not been tested on soil. Scedosporium apiospermum (Sce) is an emerging “extremophile” fungal pathogen found in built outdoor environments.

Purpose: Pilot β-Th as “natural” soil antimicrobial or for isolation of extremophiles, and to explore β-Th resistance as selective advantage to Sce in mulched landscape.

Methods: A variety of outdoor and indoor environments were used for 2 sets of 24 paired soil samples. Soil/H20 slurry (0.1 ml) was spread on …

In Vitro Growth Suppression Of Renal Carcinoma Cells By Curcumin, Santhi D. Konduri, Madhavi Latha Yadav Bangaru, Phu Thanh Do, Shenglin Chen, Jeffrey Woodliff, Sanjay Kansra

Journal of Patient-Centered Research and Reviews

Purpose

Malignant clear cell renal carcinoma (ccRCC) is an aggressive tumor highly resistant to chemotherapy and radiation. Current therapeutic approaches to management of ccRCC have not significantly improved patient survival, therefore novel therapies are needed. Activated NFκB and STAT3 expression is associated with ccRCC pathogenesis. The dietary polyphenol curcumin is a well-documented antitumor agent and a known inhibitor of NFκB and STAT3 activation. Given the lack of effective therapies that block ccRCC progression, our objective was to examine whether curcumin could suppress the growth and migration of ccRCC cells, and whether this suppression was mediated via inhibition of NFκB and …

Full Issue, Volume 3, Number 3, Journal Of Human Sciences And Extension

Journal of Human Sciences and Extension

No abstract provided.

Biochemical Effects Of Meditation: A Literature Review, William C. Daube, Charles E. Jakobsche

Scholarly Undergraduate Research Journal at Clark (SURJ)

Meditation is an activity that can help reduce stress and anxiety from daily life as well as help cultivate overall feel- ings of peacefulness, relaxation, and contentment. This review describes several studies that have been used to assess how meditation can influence the body at the molecular level. The presented results focus on small-molecule metab- olites, which are broadly defined as naturally-produced molecules that weigh less than approximately 1000 Da. The results show that meditation can significantly affect hormones and neurotransmitters such as cortisol, dehydroepi- androstrone, serotonin, melatonin, and epinephrine. Some common and modern experimental techniques that are relevant to …

Variation In Microbiome Composition And Stability For A Vancomycin Treated Primary Sclerosing Cholangitis Patient With Ulcerative Colitis Compared With Controls, Alanna Dubrovsky

Symposium

The bacterial composition of the human intestines contributes to much more than just digestion. In the inflammatory, autoimmune conditions primary sclerosing cholangitis (PSC) and ulcerative colitis (UC), the microbiome may be, in some cases, a factor. To gain a better understanding of the composition and stability of the microbiome in a patient treated with vancomycin for PSC, terminal restriction fragment (TRF) analysis was performed on 13 controls and 1 patient, and 16s rRNA microbiome composition analysis was performed on 1 patient and 3 controls. Results showed similar levels of stability, with surprising differences in composition.

Assessing The Synergistic Effect Of Caffeine And Sugar On Cognitive Performance In Undergraduate Students, Sandra P. Urquiza, Michelle Vieyra

Journal of the South Carolina Academy of Science

Working independently, both caffeine and sugar provide benefits to attention and memory. However, there is sparse literature on the synergistic effects on improved cognitive performance between caffeine and sugar when taken together. This study explored the dynamics between caffeine and sugar when consumed under ordinary conditions – as a cup of coffee. Twenty-four undergraduate students (15 women and 9 men) were asked to complete a baseline cognitive test, and one of the three variables was given at random in the form of a cup of coffee: decaffeinated with sugar, caffeinated with no sugar, and caffeinated with sugar. The remaining two …

Lessons For Life, Story Musgrave

The STEAM Journal

This piece explores the creation of character and talent through a wide diversity of education and experience.

Lifting Weights: Sculpting The Body Into An Artform, Stormi Knight

The STEAM Journal

I believe the Body is a perfectly designed machine, many people underestimate the body’s ability to do marvelous things. One of the many great things the body can do is maneuver weight. What has this to do with art-science? At first glance weight lifting may not seem like anything but part of an athlete’s routine, however when we think about women there is much more that is to do with aesthetics and real science.

Fall 2015

Scientia

Prairie prep; Chicago Wildsounds listens for ecosystem health; Up, up and away; Fulbright Travelogue: Health care in Fortaleza, Brazil; New course explores the Pope's encyclical on the environment; A "scent-sational" career in the flavor and fragrance industry; Lab notes; Paying tribute

World-Class Research: Biomedical Science Beyond Experimentation

Colby Magazine

Faculty and relationships with Maine’s big-three research labs propel Colby’s opportunities in biomedical science

Could childhood nutrition set late-life brain function?

Hitting the lab running

Ahmad wins grant for study of neurodegenerative disease

Characterization Of The Role That Alternative Ribonucleotide Reductases Play In Restoring Replication In The Presence Of Hydroxyurea In Escherichia Coli, Michael Sadek

PSU McNair Scholars Online Journal

DNA replication is essential for cells to grow and divide. Ribonucleotide reductase is an essential enzyme that is responsible for the formation of deoxyribonucleotides that are used in DNA synthesis during replication. Hydroxyurea is a chemotherapeutic agent that is thought to work by specifically inhibiting the ribonuceotide reductase to prevent replication. However, recent studies in E. coli have shown that following an initial period of inhibition, DNA synthesis then recovers in the presence of hydroxyurea, suggesting that the mode of death and cellular response to hydroxyurea is more complex than originally proposed. The E.coli genome encodes three ribonucleotide reductases that …

From Wanted To Weeds: A Natural History Of Some Of New England’S Introduced Plants, Jessamy R. Luthin

Maine History

When the Europeans first colonized New England they initiated the process of transforming the landscape into something more familiar. In order to ensure access to food and medicine and recreate the pastoral landscape of the Old World they brought with them a variety of known plant species for cultivation. With time, shifts in medical practice, agriculture, food preservation, and dietary preferences, reliance on these plants declined. As knowledge of these plant species disappeared from popular consciousness, so too did they disappear into the wilds of America, exploiting new found ecological niches, and becoming New England’s naturalized flora. Human labor was …

Factors Associated With Belief In Conspiracies About Hiv/Aids Among Hiv-Positive African-American Patients, Andrew A. Zekeri, Youssouf Diabate

Professional Agricultural Workers Journal

Abstract

The purpose of this study is to examine factors associated with belief in conspiracies about HIV/AIDS among HIV-Positive African American patients. Survey data were collected from 256 African American patients living with HIV/AIDS attending two HIV clinics in Montgomery and Dothan, Alabama. The study used multiple regression analysis to examine how sociodemographic factors contribute to belief in conspiracies about HIV/AIDS. Education and age were significantly related to belief in conspiracies about HIV/AIDS among men and women. Beliefs in conspiracies about HIV/AIDS may be a barrier to HIV prevention among African Americans. Public health officials should work toward obtaining the …

The Biological Consequences Of Kaolin Geophagia, Deloris Alexander, Desire Richardson, Lakisha Odom, Kara Cromwell, Dejuana Grant, Micoya Myers, Eddy Cadet, Hamid Mahama, Vijaya Rangari, Ralphenia Pace, Ramble Ankumah, Kokoasse Kpomblekou-A, Curtis Fluker

Professional Agricultural Workers Journal

Abstract

Kaolin geophagia is associated with the relief of gastrointestinal distress, but it may also cause adverse health effects on the body. This study was designed to: assess kaolin composition; test if 129SvEv mice would consume kaolin and determine the consequences of consumption; and assess rotational stress modulation of consumption. Thirteen kaolin samples were purchased from Alabama and Georgia stores. Chemical and physical properties were characterized for each sample using a Munsell chart, pH meter, Energy Dispersive Spectroscopy, Transmission Electron Microscopy, Visible Near-InfraRed Spectra, and Inductively Coupled Plasma-Optical Emission Spectrometry. Kaolin was then given to mice as food supplements and …

Generation And Assessment Of Muscular Mutations In Caenorhabditis Elegans, Katie N. Reget

DePaul Discoveries

A study of egg laying muscular mutations in C. elegans was conducted over a span of ten weeks. Parent (EGL-19) and wild type (N2) were exposed to mutagenesis and integration mutation techniques to generate genetic and physical different mutants. Overall, four genetic, physical and phenotypically unique worms were generated for the process of mutagenesis. The worms used in the process of integration were found to have shortened life spans, reduced size and decrease numbers of progeny.

Predictors Of Money Spent On Drugs In Substance Users, Simona Ciobotaru

DePaul Discoveries

Financial need is a major stressor for individuals who are reentering the community after substance abuse and/or incarceration. Family members and friends make up a great majority the support networks from which reentering people can receive financial support. However, that financial support could possibly contribute to drug use when the individual is actively using. The goal of this study was to further understand the implications of material and financial support specifically being transmitted from family members. This study looks at psychosocial predictors in relation to money spent on drugs in the last 30 days of 270 individuals entering substance abuse …

Phosphorylation Of Gap-43 And The Effect On App Processing, Kaitlynn Tracy, Eric Norstrom

DePaul Discoveries

The phosphorylation of Growth Associated Protein may affect the rate of interaction between GAP-43 and the Amyloid Precursor Protein. By synthesizing mutants of the GAP-43 protein, the amount of C-terminal fragments of APP that results from the interaction could be observed under various conditions. The two mutants, S41A and S41D, and the wild type GAP-43 were both co-expressed with APP in moues neuroblastoma cells and analyzed on a Western blot. The mutant used to block phosphorylation showed a greater rate of interaction with APP, while the mutant that was created to mimic the effect of phosphorylation showed less interaction. Further …

The Effect Of Hydrogen Peroxide On Leishmania Amazonensis Promastigotes, Debra Eluobaju

DePaul Discoveries

Leishmaniasis is a disease caused by the parasite Leishmania. The disease causes lesions to the skin and face; when visceral it becomes fatal to its host. Leishmanias are transmitted through the female blood-sucking sand fly into its mammalian host, where it infects macrophages. Within the macrophages, Leishmania differentiates from a motile, rod shaped, nonvirulent promastigotes to a non-motile, spherical shaped, virulent amastigotes. Differentiation is due to the high temperature of the mammalian host body, in addition to the low pH of the macrophage. In vitro, the cells are differentiated in Graces medium (pH 5.3) at 33◦C. I investigated whether …

Knowledge Of Clinical Measures And Healthcare Adherence In Young Gay And Bisexual Men Living With Hiv/Aids, Harry A. Persaud, Douglas Bruce

DePaul Discoveries

Knowledge of HIV/AIDS test results and adherence to healthcare interventions are two important outcomes that reflect proper HIV/AIDS management. This study aimed to determine which demographic and HIV acceptance measures were significantly associated with health literacy and adherence indicators in young MSM. 200 HIV/AIDS positive young MSM completed computer based surveys regarding demographics, HIV/AIDS health literacy indicators, and HIV/AIDS acceptance measures. It was found that young African American MSM, in comparison to young white MSM, had lower odds of knowing both viral load and CD4 measures; health literacy indicators. Further, participants who had a high school diploma were found to …

Measuring Rates Of Atmospheric Phosphorus Deposition Into A Fresh Water Wetland, Cassandra Shah

DePaul Discoveries

No abstract provided.

Homelessness As A Determinant Of Health Disparities Between Young Gay And Bisexual Males In Chicago, Jaclyn M. Shea, Douglas Bruce

DePaul Discoveries

There is limited research documenting health disparities between gay and bisexual males. This study aimed to examine the health behaviors and outcomes of young gay and bisexual males in Chicago, including substance use, mental health, and homelessness. Data was from a cross-sectional survey of 180 bisexual and gay males age 16-24. Bivariate results indicate that bisexual males experience higher rates of homelessness, daily marijuana use, depressive symptoms, lifetime gonorrhea and chlamydia. Logistic regression results reveal homelessness was significantly associated with marijuana use, gonorrhea, chlamydia, and depressive symptoms. Research on disparities within sexual minorities and homelessness are needed to better understand …

A High-Altitude Balloon Platform For Determining Regional Uptake Of Carbon Dioxide Over Agricultural Landscapes, Angela M. Bouche

DePaul Discoveries

Interactions between the biosphere and atmosphere are an important part of the global carbon cycle, and quantifying the carbon dioxide exchanges between them is helpful in predicting the uptake of carbon dioxide from anthropogenic sources by the biosphere in the future. In the Midwestern United States, agricultural systems cover a large part of the landscape, so understanding their role in influencing the global carbon budget is crucial as anthropogenic sources of carbon dioxide grow larger. Carbon dioxide exchanges can be measured by eddy covariance at the ecosystem level (bottom-up approach) or regionally by inversion techniques (top-down approach). Here we describe …

Diol-Mediated Versus Water-Mediated Proton Transfer Reactions, Angela Moses

DePaul Discoveries

The triple-proton-transfer reactions of 8H-1,8-naphthyridin-2-one (8H-naph) have been investigated by employing different ab initio quantum mechanical methods. The proton transfer reactions studied were facilitated through an adjacent 1,3-propanediol molecule or two adjacent water molecules. Identical proton transfer reactions were studied using a model system of 8H-naph to investigate the validity of computational approaches that use model systems to study more complex systems. The solvent effects on the structures were investigated for comparison to the initial gas phase calculations. The potential energy, reaction force, and work profiles were studied along the intrinsic reaction coordinate to monitor the developing proton transfer reactions.

Do Oaks With A Provenance Related To Warmer Climates Emit More Isoprene?, Elizabeth Carter

DePaul Discoveries

The hydrocarbon isoprene plays an important role in atmospheric chemistry, particularly in regards to air pollution and climate change. It is important to know why certain plant species emit isoprene and what factors affect its production in order to predict future air quality. Past research has indicated that isoprene aids in coping with heat stress, so it was hypothesized that source latitude (a proxy for climate) would significantly impact isoprene production by oaks grown in a common location. Twelve bur oaks collected from a latitudinal range (30-45˚) and raised at the Morton Arboretum were assayed for their isoprene emission rate …

Cave Cyanobacteria Showing Antibacterial Activity, Vasiliki Lamprinou, Kyriaki Tryfinopoulou, Emmanuel N. Velonakis, Alkiviadis Vatopoulos, Smaragdi Antonopoulou, Elizabeth Fragopoulou, Adriani Pantazidou, Athena Economou-Amilli

International Journal of Speleology

Cave Cyanobacteria - thriving in an ‘extreme’ environment with interesting species biodiversity - are supposed to be a potential source of bioactive compounds. Lipid extracts from pure cultures of two recently established Cyanobacteria from Greek caves, Toxopsis calypsus and Phormidium melanochroun, were used for antibacterial screening against human pathogenic bacteria (reference and clinical isolates). Antimicrobial Susceptibility testing for both taxa was carried out using the disc-diffusion (Kirby Bauer) method, while preliminary data applying the standard broth microdilution method for the determination of the Minimal Inhibitory Concentration (MIC) are given only for T. calypsus. Antibacterial activity was demonstrated against the …

Strategies For Leaders To Counter Social Loafing Through The Use Of Organizational Citizenship Behavior: A Literature Review, Richard Hildreth

The Compass

Social loafing (SL) is a counterintuitive phenomenon that describes a decrease of efficiency observed in both small groups and large organizations. Research over the past century has increased our understanding of SL and identified antecedent factors that appear to reduce or exacerbate its effect. Subsequent organizational models have beenconceived and evolved, starting with organizational citizenship behavior (OCB), which led toward contextualperformance (CP), and recently to contextual and citizenship performance (CCP). Each type of model can provide valuable insight explaining employee behavior and under which contexts SL occurs. Research shows that OCB has improves organizational productivity and competitiveness, due to organizational …

The Compass, Issue 2 - Forward By Provost Nodine, Arcadia University Honors Program

The Compass

Forward by Dr. Barbara Nodine, Provost and Vice President of Academic Affairs, for Issue 2 of The Compass, a scholarly journal edited and produced by students in the Arcadia University Honors Program.

The Compass, Issue 2, Arcadia University Honors Program

The Compass

Issue 2 of The Compass, a scholarly journal edited and produced by students in the Arcadia University Honors Program.

Essential Oils From Apple Mint (Mentha Suaveolens) And Passionflower Fruit (Passiflora Incarnata): Studies On Cognition, Coordination, And Chemical Components., Evelyn F. Patrick *, Jessie Bowers *, Shannon Read *, Brett R. Lackey, Christine Murphy, Sandra L. Gray

Journal of the South Carolina Academy of Science

Plant essential oils (EO) are used as perfumes, lotions and air fresheners because of their pleasant aromas, but EO also have the ability to elicit changes in mood and behavior. These activities are influenced by the mode of administration and by multiple signaling pathways. The EO aromas from organically grown apple mint (Mentha suaveolens) and passionflower fruit (Passiflora incarnata) were assessed for their effects on cognition and coordination. Participants completed two tasks designed to test working memory and bimanual task efficiency in rooms infused with apple mint, passionflower fruit or control EO. Bimanual coordination was assessed using the Intercept2 program …