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Life Sciences

2008

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Articles 1 - 30 of 87

Full-Text Articles in Medicine and Health Sciences

The Effects Of Lactation And Negative Energy Balance On Kisspeptin-Stimulated Luteinizing Hormone And Growth Hormone In Dairy Cows, Brian K. Whitlock, Joseph A. Daniel, Robyn R. Wilborn, Herris S. Maxwell, Barbara P. Steele, James L. Sartin Nov 2008

The Effects Of Lactation And Negative Energy Balance On Kisspeptin-Stimulated Luteinizing Hormone And Growth Hormone In Dairy Cows, Brian K. Whitlock, Joseph A. Daniel, Robyn R. Wilborn, Herris S. Maxwell, Barbara P. Steele, James L. Sartin

Brian K Whitlock, PhD, DVM, DACT

Kisspeptin, a neuroendocrine regulator of gonadotropin releasing hormone, is hypothesized to integrate nutrition and hormones critical to metabolism and the regulation of reproduction. Since the negative energy balance of early lactation is associated with reduced fertility via suppression of gonadotropin secretion and enhanced growth hormone (GH) responsiveness, this experiment was designed to determine the effects of stage of lactation and negative energy balance on kisspeptin-10 (Kp-10) stimulated luteinizing hormone (LH) and GH concentrations. Five nonlactating [5.1 ± 0.8 (SEM) years; 577 ± 19 kg body weight (BW)] and five lactating [4.1 ± 0.6 years; 608 ± 11 kg BW] multiparous …


Reflections On Recycling, Pollution And History Or, How To Beat The High Cost Of Living, Richard B. Philp Oct 2008

Reflections On Recycling, Pollution And History Or, How To Beat The High Cost Of Living, Richard B. Philp

Richard B. Philp

Lessons learned during the Great Depression and World War II may have to be relearned. The three Rs (reduce, reuse and recycle) were essential then to individual and national survival. A fourth R, repair, was practised as well. These lessons, if relearned, will stand us in good stead when dealing with the current economic climate as well as with problems of pollution and global warming.


Curriculum Vitae, Robert P. Lane Oct 2008

Curriculum Vitae, Robert P. Lane

Robert P. Lane

No abstract provided.


Protection Of Retinal Cells From Ischemia By A Novel Gap Junction Inhibitor, Satyabrata Das, Dingo Lin, Snehalata Jena, Aibin Shi, Srinivas Battina, Duy H. Hua, Rachel A. Allbaugh, Dolores J. Takemoto Sep 2008

Protection Of Retinal Cells From Ischemia By A Novel Gap Junction Inhibitor, Satyabrata Das, Dingo Lin, Snehalata Jena, Aibin Shi, Srinivas Battina, Duy H. Hua, Rachel A. Allbaugh, Dolores J. Takemoto

Rachel A. Allbaugh

Retinal cells which become ischemic will pass apoptotic signal to adjacent cells, resulting in the spread of damage. This occurs through open gap junctions. A class of novel drugs, based on primaquine (PQ), was tested for binding to connexin 43 using simulated docking studies. A novel drug has been synthesized and tested for inhibition of gap junction activity using R28 neuro-retinal cells in culture. Four drugs were initially compared to mefloquine, a known gap junction inhibitor. The drug with optimal inhibitory activity, PQ1, was tested for inhibition and was found to inhibit dye transfer by 70% at 10 μM. Retinal …


Intrinsic Severity As A Determinant Of Antiepileptic Drug Refractoriness, Michael A. Rogawski, Michael R. Johnson Sep 2008

Intrinsic Severity As A Determinant Of Antiepileptic Drug Refractoriness, Michael A. Rogawski, Michael R. Johnson

Michael A. Rogawski

For the most part, resistance to medications in epilepsy is independent of the choice of antiepileptic drug. This simple clinical observation constrains the possible biological mechanisms for drug refractory epilepsy by imposing a requirement to explain resistance for a diverse set of chemical structures that act on an even more varied group of molecular targets. To date, research on antiepileptic drug refractoriness has been guided by the “drug transporter overexpression” and the “reduced drug-target sensitivity” hypotheses. These concepts posit that drug refractoriness is a condition separate from the underlying epilepsy. Inadequacies in both hypotheses mandate a fresh approach to the …


Simultaneous Confidence Bands For The Coefficient Function In Functional Regression, Philip T. Reiss Aug 2008

Simultaneous Confidence Bands For The Coefficient Function In Functional Regression, Philip T. Reiss

Philip T. Reiss

No abstract provided.


What Clinical Observations On The Epidemiology Of Antiepileptic Drug Intractability Tell Us About The Mechanisms Of Pharmacoresistance, Michael Rogawski Aug 2008

What Clinical Observations On The Epidemiology Of Antiepileptic Drug Intractability Tell Us About The Mechanisms Of Pharmacoresistance, Michael Rogawski

Michael A. Rogawski

In the past several years, there have been important advances in the clinical epidemiology of antiepileptic drug resistance, as reviewed by Mohanraj and Brodie. It would appear that by and large, intractability is independent of the choice of antiepileptic drug (AED). Many patients will become seizure free on the first agent tried, irrespective of which one their physician decides to pick. Nonresponders to the first drug are in a different category: it is likely that they will continue to have seizures no matter which medicine or combination of medicines is tried. This simple clinical observation puts important constraints on the …


Vitamin Content Of Breast Milk From Hiv-1–Infected Mothers Before And After Flash-Heat Treatment, Kiersten Israel-Ballard, Barbara Abrams, Anna Coutsoudis, Lindiwe Sibeko, Lynn Cheryk, Caroline Chantry Jul 2008

Vitamin Content Of Breast Milk From Hiv-1–Infected Mothers Before And After Flash-Heat Treatment, Kiersten Israel-Ballard, Barbara Abrams, Anna Coutsoudis, Lindiwe Sibeko, Lynn Cheryk, Caroline Chantry

Lindiwe Sibeko

(EBM) as one method to reduce postnatal transmission of human immunodeficiency virus (HIV) in developing countries. Flash-heat is a simple heat treatment method shown to inactivate cell-free HIV. Objective—To determine the effect of flash-heat on vitamin content of milk. Methods—Fresh EBM was collected from 50 HIV+ mothers in Durban, South Africa. Mothers washed their hands and then manually expressed 75–150 mL EBM into sterile jars. Milk was aliquoted to unheated controls or flash-heat (50 mL EBM in a glass jar heated in a 450-mL water jacket in an aluminum pan until water boiled, then EBM removed) simulating field conditions with …


Inferring Group Differences In Brain Connectivity From Functional Magnetic Resonance Images, Philip T. Reiss Jul 2008

Inferring Group Differences In Brain Connectivity From Functional Magnetic Resonance Images, Philip T. Reiss

Philip T. Reiss

No abstract provided.


Reliability Of Functional Connectivity Networks: How Can We Assess It?, Philip T. Reiss Jul 2008

Reliability Of Functional Connectivity Networks: How Can We Assess It?, Philip T. Reiss

Philip T. Reiss

No abstract provided.


Some Thoughts On Health Department Accreditation, F. Douglas Scutchfield Md Jun 2008

Some Thoughts On Health Department Accreditation, F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


Issues And Challenges Facing The Field Of Phssr, F. Douglas Scutchfield Md Jun 2008

Issues And Challenges Facing The Field Of Phssr, F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


Public Health Professional Organizational Data, F. Douglas Scutchfield Md Jun 2008

Public Health Professional Organizational Data, F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


Big Bobby Bonaduce: Still Searching For The Rink Of Dreams, Don Morrow May 2008

Big Bobby Bonaduce: Still Searching For The Rink Of Dreams, Don Morrow

Donald Morrow

No abstract provided.


Survey Of Health Claims For Australian Foods Made On Internet Sites, H. Dragicevich, P. G. Williams, L. Ridges May 2008

Survey Of Health Claims For Australian Foods Made On Internet Sites, H. Dragicevich, P. G. Williams, L. Ridges

Peter Williams

Aim: Australia and New Zealand are currently preparing a new food standard code, which will allow the use of health claims on food products and in associated advertising. The aim of this study was to obtain preliminary information about the current use of health claims on the Internet and the level of compliance of these claims with existing regulations. Methods: From August to October 2005 a survey was conducted of 1068 websites associated with the top 20 food processing companies in Australia, and an additional 683 websites for food products found to carry health claims in previous studies of product …


Nutritional Composition Of Red Meat, P. G. Williams May 2008

Nutritional Composition Of Red Meat, P. G. Williams

Peter Williams

Lean red meats are: • An excellent source of high biological value protein, vitamin B12, niacin, vitamin B6, iron, zinc and phosphorus • A source of long-chain omega-3 polyunsaturated fats, riboflavin, pantothenic acid, selenium and possibly also vitamin D • Mostly low in fat and sodium • Sources of a range of endogenous antioxidants and other bioactive substances including taurine, carnitine, carnosine, ubiquinone, glutathione and creatine.


Food Fears: A National Survey On The Attitudes Of Australian Adults About The Safety And Quality Of Food, P. G. Williams, E. Stirling, N. Keynes May 2008

Food Fears: A National Survey On The Attitudes Of Australian Adults About The Safety And Quality Of Food, P. G. Williams, E. Stirling, N. Keynes

Peter Williams

A national telephone survey of a representative sample of 1200 Australian adults was conducted in March 2002 in order to identify the factors of greatest concern to consumers in relation to the safety and quality of food, to measure recent trends in views about hazards in the food supply, to explore beliefs about the safety of additives and to discover whether consumers use food labels to check for ingredients of concern. Forty five percent of Australians responded that they were more concerned about the safety and quality of food than they were five years previously, while only 5% were less …


Composition Of Australian Red Meat 2002. 2. Fatty Acid Profile, V. Droulez, P. G. Williams, G. Levy, T. Stobaus, A. Sinclair May 2008

Composition Of Australian Red Meat 2002. 2. Fatty Acid Profile, V. Droulez, P. G. Williams, G. Levy, T. Stobaus, A. Sinclair

Peter Williams

Australian retail samples of nine beef, six lamb, four veal and two mutton cuts were purchased from 10 retail outlets (butchers and supermarkets) in different socio-economic areas of Sydney and Melbourne. The lean and fat components were analysed for contents of total and individual fatty acids. The content of total fatty acids was less than 5g/100g edible meat in the lean component of all cuts analysed. Saturated and monounsaturated fatty acids comprised, on average, 40% and 42% respectively of total fatty acids in the lean component of red meat cuts. The saturated fatty acid content of the lean component of …


Serve Sizes Of Grain Based Foods In Australia, P. G. Williams, B. Gibson, N. Smith May 2008

Serve Sizes Of Grain Based Foods In Australia, P. G. Williams, B. Gibson, N. Smith

Peter Williams

A survey was conducted of the recommended serve sizes used on the labelling of 807 grain based foods sold in Sydney stores in 2000. These values were compared with the serve sizes used in a variety of food selection guides, including the Australian Guide to Health Eating (AGHE). In most food categories there was a great deal of variation in the serve sizes recommended, sometimes up to 20 fold. The most consistent recommendations were for sliced breads, with most manufacturers recommending two slices as a serve, and ready-to-eat breakfast cereals (one cup). The median values for cereal products were mostly …


Food Service Trends In New South Wales Hospitals, 1993-2001, R. Mibey, P. G. Williams May 2008

Food Service Trends In New South Wales Hospitals, 1993-2001, R. Mibey, P. G. Williams

Peter Williams

A survey of the food service departments in 93 hospitals throughout NSW Australia (covering 51% of hospital beds in the state) was conducted using a mailed questionnaire and the results compared with those from similar surveys conducted in 1986 and 1993. Over the past eight years there has been a significant increase in the proportion of hospitals using cook-chill food service production systems, from 18% in 1993 to 42% in 2001 (p<0.001). Hospitals with cook-chill systems had lower staff ratios than those with cook-fresh systems (8.3 vs 6.4 beds/full time equivalent staff; p<0.05), but there was no significant …


The Illawarra Healthy Food Price Index. 1. Development Of The Food Basket, P. G. Williams, M. Reid, K. Shaw May 2008

The Illawarra Healthy Food Price Index. 1. Development Of The Food Basket, P. G. Williams, M. Reid, K. Shaw

Peter Williams

Objective To define a basket of foods that could be used to monitor trends in the affordability of healthy food in the Illawarra region. Design A reference family of five was defined reflecting the population of the Illawarra region. A draft basket of foods was selected based on recommendations of the Australian Guide to Healthy Eating (AGHE), and using information on typical eating patterns from the 1995 National Nutrition Survey and data from local supermarket sales. Products were chosen to conform where possible to the National Heart Foundation guidelines for acceptability in the Pick the Tick food approval program. Seven …


Nutrient Function, Health And Related Claims On Packaged Australian Food Products - Prevalence And Compliance With Regulations, P. G. Williams, H. Yeatman, Leisa Ridges, A. Houston, J. Rafferty, A. Roesler, M. Sobierajski, B. Spratt May 2008

Nutrient Function, Health And Related Claims On Packaged Australian Food Products - Prevalence And Compliance With Regulations, P. G. Williams, H. Yeatman, Leisa Ridges, A. Houston, J. Rafferty, A. Roesler, M. Sobierajski, B. Spratt

Peter Williams

Australia and New Zealand are currently reviewing the regulations governing nutrition function, health and related claims on foods. Health claims currently are not permitted on food labels, with one exception. The aim of this study was to describe the use of such claims on packaged food for sale in Australia (excluding nutrient content claims) prior to any changes to the regulations, and measure compliance with existing regulations. A survey was conducted of the labelling of 7850 products (including multiple pack sizes of individual foods) in 47 different food categories on sale in New South Wales in 2003. A total of …


Overweight Consumers' Salient Beliefs On Omega-3-Enriched Functional Foods In Australia's Illawarra Region, C. Patch, Linda C. Tapsell, P. G. Williams May 2008

Overweight Consumers' Salient Beliefs On Omega-3-Enriched Functional Foods In Australia's Illawarra Region, C. Patch, Linda C. Tapsell, P. G. Williams

Peter Williams

Objective: To determine consumer salient beliefs toward functional foods enriched with omega-3 fatty acids. Design: Focus group interviews with adult consumers using the Theory of Planned Behavior (TPB) as a theoretical framework. Setting: Community-based residents living in the Illawarra region of New South Wales, Australia. Participants: Forty-two overweight participants (29 female; 13 male) aged 30-80y recruited by advertisement and attending one of six focus groups which were recorded and transcribed verbatim. Analysis: Content analysis was carried out and sub-categories were developed to capture the emerging themes according to the TPB model. Results: Most participants were aware of a range of …


The Illawarra Healthy Food Price Index. 2. Pricing Methods And Index Trends From 2000-2003, P. G. Williams, Y. James, J. Kwan May 2008

The Illawarra Healthy Food Price Index. 2. Pricing Methods And Index Trends From 2000-2003, P. G. Williams, Y. James, J. Kwan

Peter Williams

Objective To develop a method to monitor trends in the cost of the Illawarra Healthy Food Basket (IHFB) and report trends from 2000 to 2003. Design Detailed instructions for the method of pricing the IHFB were developed and tested. The price of the IHFB was collected each year in September at a major supermarket, green grocer and butcher in five Illawarra suburbs, representing a range of socio-economic locations. Data on welfare payments available to the reference family, assuming all members were unemployed, were collected from staff of Centrelink. Main outcome measures The average weekly cost of the IHFB, the Illawarra …


Sugar: Is There A Need For A Dietary Guideline?, P. G. Williams May 2008

Sugar: Is There A Need For A Dietary Guideline?, P. G. Williams

Peter Williams

There have been dietary guidelines in Australia since 1979 and all editions have included recommendations about sugar. This paper reviews changing recommendations in Australia, current levels of conumption, recent studies on the potential effects of nutrient dilution and dental caries, and discusses potential risks associated with a dietary guideline.


Consumer Reactions To Different Health Claim Formats On Food Labels, L. Singer, P. G. Williams, Leisa Ridges, S. Murray, Anne Mcmahon May 2008

Consumer Reactions To Different Health Claim Formats On Food Labels, L. Singer, P. G. Williams, Leisa Ridges, S. Murray, Anne Mcmahon

Peter Williams

Health claims on foods act as health messages and have a role in communicating and educating the consumer about diet-disease related issues. Previous studies have suggested that different formats of health claims communicate differently with the consumer. The aim of our study was to investigate whether splitting of the claim (a brief claim at the front package directing consumers to the back of the package where the full health claim is located) and/or endorsement of the claim (by Food Standards Australia New Zealand), have an impact on the acceptance of the claim by the consumer. Participants were recruited by a …


Composition Of Australian Red Meat 2002. 1. Gross Composition, P. G. Williams, V. Droulez, G. Levy, T. Stobaus May 2008

Composition Of Australian Red Meat 2002. 1. Gross Composition, P. G. Williams, V. Droulez, G. Levy, T. Stobaus

Peter Williams

This study aimed to update data on the gross composition Australian red meat to reflect changes in butchering practices since the 1980s and 1990s when the current values were derived. Australian retail samples of fifteen beef, eleven lamb, four veal and two mutton cuts were purchased from 10 retail outlets (butchers and supermarkets) in different socio-economic areas of Sydney and Melbourne. For both raw and cooked samples, mean external fat width (mm) was measured and the average percentage of separable internal, external and total fat, lean and waste was determined by dissection of each cut. For raw beef, total separable …


Breakfast And The Diets Of Australian Adults: An Analysis Of Data From The 1995 National Nutrition Survey, P. G. Williams May 2008

Breakfast And The Diets Of Australian Adults: An Analysis Of Data From The 1995 National Nutrition Survey, P. G. Williams

Peter Williams

The aim of this study was to describe the nutrients provided to Australian adults by the breakfast meal and compare the food and nutrient intakes and health of regular breakfast eaters and skippers. The Australian Bureau of Statistics was commissioned to undertake additional analysis of data collected in the 1995 Australian National Nutrition Survey (NNS). The survey included 24 hour recalls, physical measurements and a food habits questionnaire collected during the period February 1995 to March 1996, with a nationally representative sample of 10851 Australians aged nineteen years and older. The median nutrient intakes at breakfast and the proportion of …


Trend To Better Nutrition On Australian Hospital Menus 1986-2001 And The Impact Of Cook-Chill Food Service Systems, A. Mcclelland, P. G. Williams May 2008

Trend To Better Nutrition On Australian Hospital Menus 1986-2001 And The Impact Of Cook-Chill Food Service Systems, A. Mcclelland, P. G. Williams

Peter Williams

Objective To assess trends in the nutritional quality of hospital menus and examine differences between menus used in hospitals with cook-chill or cook-fresh food services. Design Standard patient menus were analysed against 28 criteria to assess nutritional standards and compared to results from similar studies in 1986 and 1993. Setting Menus were collected from 80 hospitals in New South Wales, Australia, including 36 using cook-chill food service systems. Statistical Analysis Chi-squared analysis was used to assess differences between the proportions of hospitals meeting the criteria in 2001 and 1993 and between different types of hospitals. Results In 2001 compared to …


Attitudes And Intentions Toward Purchasing Novel Foods Enriched With Omega-3 Fatty Acids, C. Patch, P. G. Williams, Linda C. Tapsell May 2008

Attitudes And Intentions Toward Purchasing Novel Foods Enriched With Omega-3 Fatty Acids, C. Patch, P. G. Williams, Linda C. Tapsell

Peter Williams

Objective: To identify the nature, strength and relative importance of influences on intentions to consume foods that are enriched with omega-3 fatty acids using the Theory of Planned Behavior (TPB). Design: A cross-sectional self-administered questionnaire. Setting: Community based residents living in the Illawarra region of New South Wales, Australia. Subjects: Two sub-samples were surveyed via questionnaire: Community members who responded to a local media advertisement (n=79), and subjects in a dietary intervention trial for type 2 diabetes mellitus (n=50). Variables Measures: Using the TPB variables – intention, attitude, subjective norm and perceived behavioural control - questionnaire items were constructed to …