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Articles 31 - 35 of 35
Full-Text Articles in Medicine and Health Sciences
Spline-Based Models For Predictiveness Curves, Debashis Ghosh, Michael Sabel
Spline-Based Models For Predictiveness Curves, Debashis Ghosh, Michael Sabel
Debashis Ghosh
A biomarker is dened to be a biological characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. The use of biomarkers in cancer has been advocated for a variety of purposes, which include use as surrogate endpoints, early detection of disease, proxies for environmental exposure and risk prediction. We deal with the latter issue in this paper. Several authors have proposed use of the predictiveness curve for assessing the capacity of a biomarker for risk prediction. For most situations, it is reasonable to assume monotonicity of …
Combining Multiple Models With Survival Data: The Phase Algorithm, Debashis Ghosh, Zheng Yuan
Combining Multiple Models With Survival Data: The Phase Algorithm, Debashis Ghosh, Zheng Yuan
Debashis Ghosh
In many scientic studies, one common goal is to develop good prediction rules based on a set of available measurements. This paper proposes a model averaging methodology using proportional hazards regression models to construct new estimators of predicted survival probabilities. A screening step based on an adaptive searching algorithm is used to handle large numbers of covariates. The nite-sample properties of the proposed methodology is assessed using simulation studies. Application of the method to a cancer biomarker study is also given.
Farm Focus - Spring 2010, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer
Farm Focus - Spring 2010, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer
Brian K Whitlock, PhD, DVM, DACT
No abstract provided.
The Biology Of Reality Testing - Implications For Cognitive Education, Neil Greenberg
The Biology Of Reality Testing - Implications For Cognitive Education, Neil Greenberg
Neil Greenberg
• This report explores the proposition that teaching effectiveness can be enhanced by accommodating the key differences between two complementary and deeply engrained modes of reality testing, each predominantly centered in different hemispheres of the brain. • (1) Correspondence involves “reality-testing” of a percept, the cerebral representation of an experience in the world. • (2) Coherence involves “textualizing”, that is, reality-testing of a percept by how easily it relates to previous and ongoing parallel and collateral experiences. • Confidence in the validity of any percept throughout development is related to the interplay of these key processes. • As organisms develop, …
Effects Of Intimate Partner Violence On Pregnancy Trauma And Placental Abruption, Sandra D. Lane, J. Leone, E. H. Koumans, K. Demott, M. Wojtowycs, J. Jenson
Effects Of Intimate Partner Violence On Pregnancy Trauma And Placental Abruption, Sandra D. Lane, J. Leone, E. H. Koumans, K. Demott, M. Wojtowycs, J. Jenson
Sandra D. Lane
No abstract provided.