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Full-Text Articles in Medicine and Health Sciences
A Novel Method For Synthesis Of Hydroxytyrosol, Emmanuel Onobun
A Novel Method For Synthesis Of Hydroxytyrosol, Emmanuel Onobun
Electronic Theses and Dissertations
Hydroxytyrosol, 3,4-dihydroxyphenolethanol, a naturally occurring polyphenol most common in olive tree (Olea europaea), is one of the most effective member of the polyphenols family, because of its remarkable antioxidant activity, its ability to inhibit oxidation of low density lipids (LDL), and its protection against DNA oxidative damage. Hydroxytyrosol, which is widely used in cosmetics and food supplements industries, can be purchased as an olive oil extract that contains low concentration of hydroxytyrosol besides other polyphenols. The price and low natural abundance of hydroxytyrosol make alternative synthetic sources very attractive. In this research, a novel method for the synthesis of pure …
Synthesis Of A-Cyanostilbenes And Testing Of Their Anticancer Properties, Gabrielle Cook
Synthesis Of A-Cyanostilbenes And Testing Of Their Anticancer Properties, Gabrielle Cook
Honors Theses
This research project involves synthesizing cyanostilbenes and testing their anticancer properties in breast cancer cells. Breast cancer is a global issue, one that great improvement has been found in the last few decades, but also one that remains a large killer. The components of the cyanostilbene hybrids have all been shown to have anticancer properties on their own, and we would like to see if we can increase these properties by combining multiple into a single hybrid. Then these cyanostilbene compounds are tested on Her2+ human breast cancer cells. The goals is to assess whether or not the cyanostilbenes have …