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Presence Of Increased Mast Cells In Infants And Children With Volume And Variety Limited Intake., Amy Issa, Jensen Edwards, Meenal Singh, Craig A. Friesen, Sarah T. Edwards
Presence Of Increased Mast Cells In Infants And Children With Volume And Variety Limited Intake., Amy Issa, Jensen Edwards, Meenal Singh, Craig A. Friesen, Sarah T. Edwards
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BACKGROUND: Reports indicate patients with feeding difficulties demonstrate signs of inflammation on biopsies, notably eosinophilia, but it is unknown whether mast cell density contributes to variety or volume limitation symptoms. The aim of our study was to evaluate eosinophil and mast cell density of EGD biopsies in pediatric patients with symptoms of decreased volume or variety of ingested foods.
METHODS: We conducted a single-center, retrospective chart review of EMRs for all new feeding clinic patients between 0 and 17 years of age. Patients were categorized by symptoms at the initial visit as well as eosinophil and mast cell densities in …