Medicine and Health Sciences Commons^™

J Mich Dent Assoc September 2023

The Journal of the Michigan Dental Association

Reports from the deans of Michigan’s two dental schools covering the past year’s activities serve as the dual cover stories for this issue. Other feature articles include a discussion of professionalism, a diagnostic challenge describing adenomatoid odontogenic tumor, and a memorial tribute to recently deceased MDA Executive Director Karen Burgess. Monthly departments include Dentistry and the Law, Staff Matters^® human resource guidance, MDA Services (endorsed programs), MDA Foundation, news updates in News You Need, and more.

Comparison Of Thickness Between Thermoformed And Printed Orthodontic Aligners, Omar Souman

Loma Linda University Electronic Theses, Dissertations & Projects

Introduction: The fabrication of thermoformed orthodontic aligners involves processes that irreversibly alter material properties, resulting in aligners that exhibit high variation in thickness. The non-uniform thickness can lead to unpredictable forces that can adversely affect orthodontic tooth movement. With recent technological advancements enabling the printing of orthodontic aligners, it is of clinical interest to investigate their variation of thickness.

Purpose: This study utilized Micro-Computed Tomography (Micro-CT) and Geomagic Control X metrology software to compare the thickness of thermoformed and direct printed aligners.

Materials and Methods: Intraoral scans of 13 orthodontic patients were used to generate standard tessellation …

Spatially-Aware Clustering Improves Ajcc-8 Risk Stratification Performance In Oropharyngeal Carcinomas, Guadalupe Canahuate, Andrew Wentzel, Abdallah S R Mohamed, Lisanne V Van Dijk, David M Vock, Baher Elgohari, Hesham Elhalawani, Clifton D Fuller, G Elisabeta Marai

Faculty, Staff and Student Publications

OBJECTIVE: Evaluate the effectiveness of machine learning tools that incorporate spatial information such as disease location and lymph node metastatic patterns-of-spread, for prediction of survival and toxicity in HPV+ oropharyngeal cancer (OPC).

MATERIALS & METHODS: 675 HPV+ OPC patients that were treated at MD Anderson Cancer Center between 2005 and 2013 with curative intent IMRT were retrospectively collected under IRB approval. Risk stratifications incorporating patient radiometric data and lymph node metastasis patterns via an anatomically-adjacent representation with hierarchical clustering were identified. These clusterings were combined into a 3-level patient stratification and included along with other known clinical features in a …

Toxic Vs. Visionary Leaders, Michelle C. Dziurgot Dds

The Journal of the Michigan Dental Association

This reviews characteristics of toxic and visionary leadership styles. This article is an installment of the MDA Journal’s monthly Editorial department.

Detroit Mercy Dental: Empowering Leaders And Igniting Change, Mert N. Aksu Dds, Jd, Mhsa, Cert. Dph

The Journal of the Michigan Dental Association

This article is a review/recap of activities at the University of Detroit Mercy School of Dentistry over the past year, including information on community service programs, diversity and inclusion, research, faculty and staff accomplishments, student life, and demographic information.

Mda Foundation: How Foundation Grants Assist Dei Efforts At Detroit Mercy, U-M, Anne Berquist

The Journal of the Michigan Dental Association

This article provides information on the diversity, equity, and inclusion programs at Michigan’s two dental schools and details how the MDA Foundation is supporting these programs. This article is an installment of the MDA Journal’s monthly MDA Foundation department.

Perio Presentation - The Gummy Smile

Journal of the Macomb Dental Society

Presentation summary: Ninety-two attendees ranging from dental specialists, generalists, and hygienists gathered at Andiamos as a team to learn treatment modalities for “Gummy Smiles.” Beautifully documented and photographed cases were shared. Classifications of “Gummy Smile” patients were reviewed. Dental teams can feel confident discussing treatment options concerning high smile lines thanks to Drs. Kinaia and Hasso.

Karen Burgess Remembered: Thoughts And Memories From Mda Leaders

The Journal of the Michigan Dental Association

This article is a collection of memories and remembrances of Karen Burgess, who served as Michigan Dental Association CEO/executive director from 2014 until her death on July 18, 2023.

Mda Services: Why Dental Cpas Are Warning About Potential Employee Dishonesty, Reva Darling

The Journal of the Michigan Dental Association

This article details scenarios in which embezzlement and employee dishonesty can occur in a dental office and the need to employ a dental CPA. The article also describes two vendors endorsed by the Michigan Dental Association for accounting and protection against embezzlement. This article is an installment of the MDA Journal’s bi-monthly MDA Services department.

U-M School Of Dentistry: A New Leader, But The Same Longstanding Commitment To Advancing Dental Education And Oral Health Sciences, Jacques E. Nör Dds, Ms, Phd

The Journal of the Michigan Dental Association

This article is a review/recap of activities at the University of Michigan School of Dentistry over the past year, including introducing the new dean of the school, Dr. Jacques Nör, the mission of the school, student demographic information, community outreach, faculty news, student achievement, and research.

Implant Survival In Tissue-Engineered Mandibular Reconstruction-Early Experiences, Victoria A Mañón, Nicholas Oda, Emeric Boudreaux, Huy Tran, Simon Young, James C Melville

Faculty, Staff and Student Publications

Study design: This article is to evaluate the early outcomes of dental implants placed in bone generated with tissueengineering techniques, specifically recombinant human bone morphogenic protein-2 (rhBMP-2), allogeneicbone particulate, and bone marrow aspirate concentrate (BMAC) in patients with resection of benignpathology.

Objective: To evaluate the long-term prognosis of dental implants placed in tissue engineered mandibular reconstruction.

Methods: We retrospectively evaluated 12 patient records, all of whom underwent segmental mandibular resection of benign pathology and reconstruction with a combination of BMAC, rhBMP-2, and allogeneic bone. Collecteddata points included the patient's age, gender, medical and social histories, implant site and placement date, …

Patient Shielding During Dentomaxillofacial Radiography: Recommendations From The American Academy Of Oral And Maxillofacial Radiology, Erika Benavides, Avni Bhula, Anita Gohel, Alan G Lurie, Sanjay M Mallya, Aruna Ramesh, Donald A Tyndall

Faculty, Staff and Student Publications

BACKGROUND: The American Academy of Oral and Maxillofacial Radiology established an ad hoc committee to draft evidence-based recommendations and clinical guidance for the application of patient contact shielding during dentomaxillofacial imaging.

TYPES OF STUDIES REVIEWED: The committee reviewed monographs and reports from radiation protection organizations and studies that reported radiation dose to gonads, breasts, and thyroid gland from dentomaxillofacial imaging.

RESULTS: Considering the absence of radiation-induced heritable effects in humans and the negligible dose to the gonads and fetus from dentomaxillofacial imaging, the committee recommends discontinuing shielding of the gonads, pelvic structures, and fetuses during all dentomaxillofacial radiographic imaging procedures. …

Epigenome-Wide Association Study Using Peripheral Blood Leukocytes Identifies Genomic Regions Associated With Periodontal Disease And Edentulism In The Atherosclerosis Risk In Communities Study, Naisi Zhao, Flavia Teles, Jiayun Lu, Devin C Koestler, James Beck, Eric Boerwinkle, Jan Bressler, Karl T Kelsey, Elizabeth A Platz, Dominique S Michaud

Faculty, Staff and Student Publications

AIM: To investigate individual susceptibility to periodontitis by conducting an epigenome-wide association study using peripheral blood.

MATERIALS AND METHODS: We included 1077 African American and 457 European American participants of the Atherosclerosis Risk in Communities (ARIC) study who had completed a dental examination or reported being edentulous at Visit 4 and had available data on DNA methylation from Visit 2 or 3. DNA methylation levels were compared by periodontal disease severity and edentulism through discovery analyses and subsequent testing of individual CpGs.

RESULTS: Our discovery analysis replicated findings from a previous study reporting a region in gene ZFP57 (6p22.1) that …

The Biocompatibility Of A Ginger-Containing Herbal Toothpaste On Developing Zebrafish Embryos, Simge Meseli, Unsal Veli Ustundag, Perihan Seda Ates, Ismail Unal, Ebru Isik Alturfan, Dilek Tağtekin, Funda Yanikoglu

Journal of Dentistry Indonesia

The biocompatibility of toothpaste in an oral cavity should be approved by clinical trials. Nowadays, herbal toothpaste is increasing in popularity due to its natural ingredients. Being genetically similar to humans, zebrafish are used in potential toxicity testing. The zebrafish embryotoxicity test is a fast and straightforward method to study chemical toxicity during embryogenesis.

Objective: This study aimed to evaluate if there was any biocompatibility of the toothpaste on zebrafish embryos.

Methods: Adult AB strain zebrafish were used according to Institutional Animal Care and Use Committee protocols. Normally dividing, spherical embryos were exposed to herbal toothpaste with ginger (Gumgumix, Turkey) …

The Successful Management Of Non-Healing Extraoral Draining Sinus Of Odontogenic Origin: A Report Of Two Cases, Eason Soo, Nurul Ain Ramlan, Sarah Husna Khairulzan, Rifqah Nordin, Muhammad Syafiq Asyraf Rosli

Journal of Dentistry Indonesia

Extraoral draining sinus of odontogenic origin usually lacks intraoral symptoms, thus it may be diagnosed as a cutaneous lesion. It is rare and may be confused with a wide variety of diseases for example furuncle, pericoronitis in relation to the mandibular third molars, parotid fistula, preauricular sinuses, periapical and periodontal pathology, and many more. Patients might seek treatment from their physician as they are not aware of its odontogenic origin and these cases usually are misdiagnosed and leading to inappropriate treatment.

Objective: To discuss the detailed management of two cases of extraoral draining sinus that were successfully treated.

Case Reports: …

Oral Leukoplakia: Diagnosis And Management Revisited, Isaäc Van Der Waal

Journal of Dentistry Indonesia

The definition of oral leukoplakia has not much changed during the past five decades and is still a definition by exclusion of ‘known’ lesions. Therefore, a diagnosis of leukoplakia is not always a straightforward one for the clinicians and, to some extent, also for the pathologists. The traditional clinical classification in homogeneous and nonhomogeneous leukoplakia may just be simplified into leukoplakia (thin and thick/verrucous) and erythroleukoplakia. In spite of numerous reported predictive molecular and genetic parameters of malignant transformation, the presence and grade of epithelial dysplasia as assessed by histopathological examination is still the most important one. Of the various …

Comparison Of Centering Ability And Canal Transportation Of Trunatomy Files With Different File Systems, Ecehan Hazar, Gediz Geduk, Ezgi Coşkun, Sibel Koçak, Baran Can Sağlam, Mustafa Murat Koçak

Journal of Dentistry Indonesia

Objective: This study aims to evaluate the centering ability and canal transportation of the ProTaper Next, One Curve, and TruNatomy instruments in curved root canals. Methods: Forty-five curved mesiobuccal canals of human mandibular molar teeth were selected, randomly divided into 3 groups, and prepared using the ProTaper Next, One Curve, and TruNatomy files. Cone Beam Computed Tomography images of the cross-sectional planes at 1 mm, 3 mm, 5 mm, and 7 mm from the apical foramen were determined before and after the preparation. For each specified millimeter canal transportation and centering ability were measured. Statistical analysis was performed …

Comparison Of Two Different Intraoral Scanners For Determination Of Caries Related Volume Loss In Caries Removal, Merve Şeker, Elif Alkan, Dilek Tağtekin, Bora Korkut, Funda Yanıkoğlu

Journal of Dentistry Indonesia

Objective: The study aimed to compare cavity volume data obtained with two different intraoral scanners. Methods: One hundred extracted molar teeth were divided into groups according to ICDAS-II classification, and scanned with Cerec Omnicam (Dentsply Sirona) and iTero Element Flex (Align Technology). The caries-infected tissues were removed regarding either minimally invasive or conventional cavity principles. Samples were scanned again and volumetric data were assessed by Meshmixer 3.5 (Autodesk) 3D modeling software. Statistical evaluations were performed with Mann Whitney U test and Spearman’s Correlation test. The significance level was α=0.05. Results: Although there was a significant difference between obtained …

Salivary Changes In Patients Hospitalized For Complications Of Hiv Infection/Aids: A Study Using Inductively Coupled Plasma Optical Emission Spectrometry, Vanessa Cavassin Klamas, Mateus Anhaia Ventura, Loana Mara Baika, Adryano Arana Kamei, Jhonatan Yukio Naka, Cassiano Lima Chaiben, Marco Tadeu Grassi, Antonio Adilson Soares De Lima

Journal of Dentistry Indonesia

Objective: The aim of this study was to analyze the salivary flow and levels of major salivary ions of HIV-infected individuals. Methods: One hundred and two participants (18 - 74 years of age) were divided into two groups (51 HIV - infected patients and 51 controls) and had a saliva sample collected. Salivary flow rate was measured gravimetrically. Levels of salivary sodium, potassium, magnesium, calcium and phosphorus were analyzed by inductively coupled plasma optical emission spectrometry (ICP-OES). Results: The mean salivary flow of subjects with HIV infection was significantly higher when compared to controls (Case group = …

Perceived Stress, Severity Of Xerostomia, And Periodontal Status In Undergraduate Dental Students, Engku Ahmad Muzhaffar, Zurairah Berahim, Norsila Abdul Wahab, Norkhafizah Saddki

Journal of Dentistry Indonesia

Dentistry is a highly stressful program; stress is associated with xerostomia and periodontal disease.

Objective: This study aims to investigate the association of perceived stress, severity of xerostomia, and periodontal status in dental students.

Methods: This was a two-phase cross-sectional study of 245 Universiti Sains Malaysia (USM) undergraduate dental students. Phase 1 involved administration of the Perceived Stress Scale (PSS-10) and Summated Xerostomia Inventory (SXI). In phase 2, the Community Periodontal Index (CPI) was performed on 150 students to determine their periodontal status.

Results: Mean PSS-10 and SXI scores were 19.6 (SD 5.47) and 7.9 (SD 2.04), respectively. …

Cone-Beam Computed Tomography Assessment Of Morphologic And Anatomic Changes Of The Nasopalatine Canal: Cross-Sectional Study, Hümeyra Tercanlı, Ayşe Taş, Gamze Coşan Ata

Journal of Dentistry Indonesia

Objective: To reveal the morphological and anatomical structure of the nasopalatine canal (NPC) and analyze its measurements via cone-beam computed tomography (CBCT).

Methods: A total of 246 CBCT images were included in the study.) NPC diameter, length, angle, distance from the IF to buccal bone (M1), distance from the NF to buccal bone (M2), and the distance from the middle of the NPC to buccal bone (M3) were measured. Statistical significance was assumed at p < 0.05.

Results: There was a significant difference between gender and NPC length, M1 and M3 (p = 0.008, p = 0.019 and p < 0.001, respectively), and between the presence of teeth in the anterior maxilla and M1 (p < 0.001). There was a significant difference between the shape of NPC in the coronal plane and NPC angle (p = 0.012) and between the shape of NPC in the sagittal plane and NF diameter, IF diameter, M1 and the M3 (p < 0.001, p = 0.006, p = 0.031 and p < 0.001, respectively).

Conclusion: NPC variations, …

How To Manage Fan’S C Shape Canals Along With S Shape Morphology In Indian Population: A Case Series And Narrative Review, A Lavanya, Rajendra Kumar Tewari

Journal of Dentistry Indonesia

The C-shaped root canals offer greater negotiation, debridement, and obturation difficulty as they present with intercommunications, lateral canals, and reduced dentin thickness.

Objective: This case series elaborates on the recognition that these varying configurations is important to enhance adequate cleaning, shaping, and sealing of the root canal.

Case Reports: On clinical examination, all the teeth showed caries were nonresponsive to sensibility tests and toother diagnostic tests, suggestive of pulp necrosis with apical periodontitis. Conventional root canal treatment with different techniques and obturation systems have been used. This case series presents the successful management of various C-shaped configurations classified by Fan …

The Effects Of Boric Acid On The Water Solubility Of Glass Ionomer Cements, Banu Cukurluoz Bayındır, İrem Bağ

Journal of Dentistry Indonesia

Changing the water solubility property of glass ionomer cement (GIC), which is frequently used in pediatric dentistry, is the starting point of this study. Objective: To evaluate the effects of boric acid on the water solubility (WS) of GIC. Methods: The samples were prepared as n=12 in each of four groups: GIC-Conventional glass ionomer cement; BGIC with 1:3 boric acid added to conventional GIC powder; RMGIC-resin-modified glass ionomer cement; BRMGIC with 1:3 boric acid added to RMGIC powder. Weight changes were compared 1, 3 and 24 h after keeping in distilled water. One sample in each group was …

Misusing Elastics For Midline Diastema Closure - Disaster And Treatment Via A Case Report In Vietnam, Vo Nhu Truong Ngoc, Ly Van Huan, Hoang Kim Loan, Dang Trieu Hung, Ta Thanh Dong

Journal of Dentistry Indonesia

Midline diastema has been a popular aesthetic problem for children. Several treatment options are available, however, the use of elastic bands without other appliances for closing the diastema still remains a pressing issue in Vietnam, which could be done by the patient’s parents either themselves or under the dental practitioners’ suggestion.

Objective: To report a specific case about the extensive extrusion regarding upper central incisors in a pediatric patient due to misusing the elastic band, in which management was complex due to an unfavorable situation for splinting.

Case Report: Single rubber band usage for orthodontic movement in closing diastema has …

Association Between Acculturation, Dental Floss Use, Dental Visits And Unmet Dental Needs Among Asians In The United States: Findings From National Health And Nutrition Examination Survey (Nhanes) 2011–2018, Ting Luo, Kaylin Beiter, Tung Sung Tseng

School of Graduate Studies Faculty Publications

Objectives: The objectives of this study were to examine the associations between acculturation and dental floss, regular dental visits and unmet dental care needs among Asian Americans, as well as the moderating effects of these associations. Methods: This study analysed national representative samples from the National Health and Nutrition Examination Survey (NHANES) 2011–2018. A total of 2763 Asian Americans aged 20 and older were included in this analysis. The primary predictor, acculturation score, was determined by three questions: (i) language spoken at home (higher score for English), (ii) country of birth (higher score for United States) and (iii) length of …

Novel Diagnostic And Therapeutic Approaches To Temporomandibular Dysfunction: A Narrative Review, Brendan Moxley, William Stevens, Joel Sneed, Craig Pearl

Faculty, Staff and Student Publications

Temporomandibular dysfunction (TMD) is a burgeoning area of study within the dental field. TMD is caused by abnormalities in the temporomandibular joint or muscles of mastication and can lead to pain, loss of function, and other complications. As this area of patient care receives increased focus, the ability to accurately diagnose TMD becomes paramount. The aim of this review is to summarize novel diagnostic and therapeutic techniques that have been proposed within the last approximately 3 years in order to inform readers of the cutting-edge advances in the field of TMD diagnosis and management, while also analyzing the clinical relevance …

Effects Of Surface Treatment Method Forming New Nano/Micro Hierarchical Structures On Attachment And Proliferation Of Osteoblast-Like Cells, Jae-Seung Im, Hyunsuk Choi, Hyun-Wook An, Tae-Yub Kwon, Min-Ho Hong

Faculty, Staff and Student Publications

Titanium (Ti) and Ti-based alloys are commonly used in dental implants, and surface modifications of dental implants are important for achieving osseointegration (i.e., direct connection between the implant surface and bone). This study investigated the effect of an eco-friendly etching solution-a hydrogen peroxide-sodium bicarbonate mixture-on the surface properties and contact angles of osteoblast adhesion and proliferation on Ti surfaces. Disk-shaped Ti specimens were prepared using different surface treatments (machining, sandblasting, and sandblasting/acid-etching), and they were immersed in the etching solution and ultrasonically cleaned. Surface characterization was performed using scanning electron microscopy, digital microscopy, contact angle analysis, and X-ray photoelectron spectroscopy. …

Bulletin Of The Virginia State Dental Association (Vol. 38, No. 2, 1961)

Bulletin of the Virginia State Dental Association

No abstract provided.

Association Of Inflammatory Markers And Growth Factors With Radiographically Assessed Wound Healing Of Extraction Sockets, Sasha Mohammadi

Theses & Dissertations

The purpose of this prospective cohort pilot study was to investigate the association of the periodontal status and inflammatory markers from the gingival crevicular and wound fluid with the healing outcomes following tooth extraction. The central research hypothesis is that extraction sites and the adjacent teeth that exhibit increased markers of inflammation, or decreased growth factors, at baseline or 2 weeks will be associated with reduced healing outcomes observed radiographically 3 months following surgery. Nine patients at the UNMC College of Dentistry who were seeking care to extract a posterior tooth due to advanced periodontal bone loss, non-restorable caries or …

Reducing Oral Health Disparities: Effectiveness Of Preventive Dental Care On Treatment Use, Expenditures And Determinants Of Service Utilization, Rashmi Lamsal

Theses & Dissertations

Given the importance of oral health in maintaining the general health and well-being of an individual, this dissertation includes three independent studies examining dental care utilization and expenditures among adults in the U.S. The first study examines the effectiveness of preventive dental visits on treatment utilization and expenditures among adults aged 18 and above. The second study focuses on the impact of paid sick leave on different types of dental services utilization among working adults aged 18-64. Finally, the last paper compares the differences in dental care utilization and related expenditure between foreign-born and US-born adults with diabetes. The paper …