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Full-Text Articles in Medicine and Health Sciences
Immunohistochemical Localization Of Cytokeratin, Vimentin And Alpa-Smooth Muscle Actin Micro And Intermediate Filaments In Canine Mammary Tumors, Ümi̇t H. Mi̇lli̇, Rifki Haziroğlu, Yilmaz Aydin, M. Yavuz Gülbahar
Immunohistochemical Localization Of Cytokeratin, Vimentin And Alpa-Smooth Muscle Actin Micro And Intermediate Filaments In Canine Mammary Tumors, Ümi̇t H. Mi̇lli̇, Rifki Haziroğlu, Yilmaz Aydin, M. Yavuz Gülbahar
Turkish Journal of Veterinary & Animal Sciences
Forty-six formalin-fixed paraffin-embedded canine mammary tumors, 15 benign and 31 malignant, were studied immunohistochemically. Mouse monoclonal anti-alpha-cytokeratin 18, mouse monoclonal anti-alpha-cytokeratin (pan cytokeratin), mouse monoclonal anti-alpha-smooth muscle actin and mouse monoclonal anti-vimentin antibodies were used. The ductal and acinar epithelium stained positively for cytokeratin 18 and pan cytokeratin, although there was no immunoreactivity in some tumors. Metaplastic squamous cells in two solid carcinomas were positive for both cytokeratin 18 and pan cytokeratin. It was a notable finding that there were unreactive epithelial cells in some tumors for broad spectrum cytokeratin antibody (pan cytokeratin). Myofibroblasts in benign and malignant tumors were …
Epidermal Growth Factor Receptor (Egfr) Immunolocalization In The Male Rat Reproductive Tract During Pre-And Postnatal Periods, Celal Kaloğlu, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu
Epidermal Growth Factor Receptor (Egfr) Immunolocalization In The Male Rat Reproductive Tract During Pre-And Postnatal Periods, Celal Kaloğlu, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu
Turkish Journal of Veterinary & Animal Sciences
A number of recent studies suggest the effects of several growth factors as well as genetic factors on the development and differentiation of the testes and excretory ducts. One of the most important growth factors affecting the development and differentiation of the above-mentioned organs may be epidermal growth factor (EGF). Therefore, the aim of the present study was to investigate the effects of EGF on the development of the testes and excretory ducts of male rats by determining the immunolocalization of EGF receptors in these organs during foetal and postnatal periods. To do this, testicular and excretory duct tissue samples …