Medicine and Health Sciences Commons^™

Effect Of Amputation On Muscle Structure Properties In A Rabbit Model, Roy Caleb Stubbs

Masters Theses

After amputation, muscles in the residual limb are detached from their insertion points and no longer span the missing joints. Our objective was to quantify the effect of amputation-induced disuse on residual muscle structure, an indirect indicator of muscle force-generating capacity. One hind paw was surgically removed at the ankle joint of ten rabbits. At two weeks (n=5) and 4 weeks (n=5) post-amputation and for select muscles (gastrocnemius, soleus, tibialis cranialis, extensor digitorum, and flexor digitorum superficialis), we measured and computed several muscle structure properties. Additionally, we qualitatively assessed the muscle fiber appearance of histological samples at each timepoint. At …

Comparative Anatomical Study Of The Brachial Plexus Of Primates, Alison Leann Camero

Masters Theses

Old world monkeys, new world monkeys, and humans all originate from a common ancestor. Although humans and old world monkeys are phylogenetically more closely related, old world monkeys and new world monkeys have similar locomotion. A difference in muscle patterns exists between old world monkeys, new world monkeys, and humans. Different musculature may be due to differences in locomotive patterns and species-specific use of their forearms. Muscles in the forelimbs are innervated by the nerves of the brachial plexus. There are differences among the brachial plexuses of human and non-human primates as well as variability within the species.

In this …

Blood Flow Restriction And Various Intensity Exercise In The Upper Extremity, Noelle Ashlyn Kaminski, Andrew Lowe

Masters Theses

Purpose: To determine if using Blood Flow Restriction (BFR) combined with low-load exercise can elicit an increase in strength and tendon size of the distal biceps tendon when compared to high-load exercise protocol. Methods: Twenty-one participants (11 M, 10 F; 2 Left-handed: 19 Right-handed; Age range 18-25yoa) were randomized to either the treatment group (BFR + low load exercise) or the control group (high load exercise). Participants were enrolled in a 7-week exercise protocol, with exercise sessions held twice weekly. The first week included measurements of each participant's 1 repetition maximum (1RM) and ultrasound measurements of the dominant distal bicep’s …

Visuomotor Adaptation During Asymmetric Walking, Charles Napoli

Masters Theses

Necessary for effective ambulation, head stability affords optimal conditions for the perception of visual information during dynamic tasks. This maintenance of head-in-space equilibrium is achieved, in part, by the attenuation of the high frequency impact shock resulting from ground contact. While a great deal of experimentation has been done on the matter during steady state locomotion, little is known about how head stability or dynamic visual acuity is maintained during asymmetric walking.

In this study, fifteen participants were instructed to walk on a split-belt treadmill for ten minutes while verbally reporting the orientation of a randomized Landolt-C optotype that was …

Tight Trip Vs. Loose Grip On Russian Kettlebell Swing Work Capacity, Austin Deshner, Abigail Mccarty, Jerrell C. Campbell, Andrew Fields, Will W. Peveler

Masters Theses

The purpose of this study was to examine the effects of a tight grip(TG) and a loose grip(LG) on work capacity while performing Russian kettlebell swings(KBS). It was hypothesized that LG would result in an ability to perform more work. Thirty fit adults (16 male; 14 female) were tested. Two (TG and LG) separate counterbalanced trials for each subject were collected, counting the number of repetitions completed until volitional exhaustion. RPE for forearms and overall exhaustion were collected post-trial. SPSS was used to run a paired samples t-test. There was a significant difference between the two grips (p = 0.013)(TG …

The Acute Impact Of Stair Climbing On Vertical Jump Height, Matthew Grossman

Masters Theses

Vertical jump (VJ) is a strong determinant of explosive power in the trained and untrained population. There is agreement among the literature that vertical jump training can be improved through progression in specific training related to vertical jump. For example, plyometrics is a widely studied training method for increasing VJ, and has been generally accepted method for increasing VJ. Within the literature, training methods are continually being studied to improve athletic performance. Exploration of improvements outside of resistance training can provide further insight on enchancing athletic performance. The present study examined the acute impact of stair climbing (SC) on VJ. …

Exploration Of The Association Between Muscle Volume And Bone Geometry Reveals Surprising Relationship At The Genetic Level, Prakrit Subba

Masters Theses

The evolution of jaws in cichlid fishes of the East African Great Lakes is a textbook example of adaptive radiation in vertebrates. Karl Liem postulated that this adaptive radiation has been possible due to the functional decoupling of two cichlid functional units – the pharyngeal jaw (PJ) and the oral jaw (OJ). This functional decoupling of the jaws has enabled the OJ to be relieved of its dual role of prey capturing and processing and has allowed the PJ to take on the role of prey processing. As a result, African cichlids have adapted the morphology of their functional units …

Impact Of Parity On Gait Biomechanics, Bekah P. Stein

Masters Theses

Background: Symptomatic knee osteoarthritis (OA) is an incurable condition that affects nearly 50% of adults, and women are twice as likely as men to develop OA. Throughout pregnancy, women experience large changes in morphology and gait mechanics, as well as changes in joint loading. It is possible these adaptations could cause lasting changes postpartum, which may potentially contribute to initiation of OA, thereby increasing the overall risk of OA for women.

Purpose: This exploratory study looked to identify differences between lower limb gait mechanics of healthy nulliparous women and healthy parous women.

Methods: 28 healthy female participants (14 parous, 14 …

The Relationship Between Feeding Type And Temporomandibular Joint Morphology In Superfamily Musteloidea, Travis L. Garvin

Masters Theses

Many studies have focused on the soft tissue analysis of carnivores and have demonstrated a relationship between feeding biomechanics and feeding types. Herbivores and omnivores rely heavily on anteroposterior and helical movement of the mandible and teeth for the breakdown of fibrous foods resulting in a flat mandibular fossa while the function of the carnivore TMJ is different, as they need a much stable joint for ripping and tearing of the flesh. I aim to look at whether the bony morphology of the temporomandibular joint (TMJ) can be directly related to feeding type, specifically in the superfamily Musteloidea. I sampled …

Effects Of 17Β Estradiol In The Metabolism And Morphology Of Bluegill Sunfish (Lepomis Macrochirus), Neeta Parajulee Karki

Masters Theses

Fish natural habitats are increasingly contaminated with various estrogenic compounds, including 17β estradiol (E2). This compound causes adverse effects on the reproductive system of male fish; however, the effects of E2 on other aspects of fish metabolism, morphology and histopathological changes in internal organs are not well known. The objective of this study is to evaluate the effects of E2 exposure on the basal and stressed metabolic rate, morphological changes in body shapes, and histological changes in the liver tissues of sunfish species. Fish were held individually in ten gallon tanks under two treatments of 40 and 80 ng/L and …

Stretching With Whole Body Vibration Versus Traditional Static Stretches To Increase Acute Hamstring Range Of Motion, Anastasia Elizabeth Bourne

Masters Theses

PURPOSE The purpose of this study was to determine if performing static active knee extension hamstring stretching using the Pneumex Pro-Vibe vibrating platform increased acute hamstring range of motion (ROM) greater than traditional static active knee extension hamstring stretching. METHODS: A within subject design was utilized with subjects undergoing static stretching with vibration and without vibration (conditions counterbalanced). Pre- and post-test active and passive ROM was measured for the right leg, with subjects first undergoing a 5-minute warm-up on a stationary bicycle. Supine active knee extension was performed on the Pro-Vibe platform with and without vibration. The stretch was held …

The Effects Of Differing Bicycle Frame Geometry On Muscle Recruitment Strategies And Power During A 30-Second Wingate Anaerobic Test, Patrick Hills-Meyer

Masters Theses

The purpose of this study was to test how changing the bicycle frame geometry; from a shallow frame geometry [seat tube angle (STA) of 72°] to a steep frame geometry (STA of 82°) affected the electromyographic (EMG) signal of the hamstrings [biceps femoris (BF) and semitendinosus (ST) muscles] and the quadriceps [vastus medialis (VM) and vastus lateralis (VL)] and power (max, mean, min, and, % drop) during a Wingate anaerobic test (WAT). To measure the muscle recruitment and power, 12 experienced triathletes were prepped with surface electrodes to measure EMG amplitude and an electrogoniometer to measure knee joint angle while …

A Kinematic And Kinetic Analysis Of First, Fourth, And Fifth Positions In The Classical Ballet Method, Mary Sue Hill

Masters Theses

The problem of the study was to compare electromyography (EMG) responses, ground reaction forces, and torques on female college-age dancers' knees in selected positions. Subjects were 18 female dancers, aged 18 to 30 years, with 6 subjects from each of three levels: Ballet Technique I, II, and III. The rectus femoris, vastus lateralis, and vastus medialis were analyzed in a grande plie in three positions, (1) first, (2) fourth, and (3) fifth, with two phases: (1) eccentric, and (2) concentric. No differences in force or EMG data were found for the concentric phases of the three positions. Significant differences were …

Pain Levels And Rating Of Perceived Exertion Of People With Herniated Lumbar Disc While Walking In Two Environments, Brenda L. Cunningham-Boerger

Masters Theses

The purpose of the study was to investigate if walking in water is an effective substitute for walking on land as an aerobic exercise for people with herniated lumbar disc. The study involved the dependent variables o f perceived pain levels (PPL) and ratings o f perceived exertion (RPE). Independent variables were walking condition and work intensity. Land walking was performed on a treadmill; water walking was performed in an indoor pool 4.5 ft deep and 90*F. Work was set at four different intensities, based on the formula for predicting maximum heart rate (MHR), 220 minus age. The graded work …

The R Value At Vo2 Max During Maximal Graded Exercise Treadmill Tests Of Coronary Artery Diseased And Nondiseased Subjects, Sherry S. Williams

Masters Theses

This study examined the R value at VO2 max during maximal graded treadmill exercise tests to determine if it was a reliable indicator of VO2 max and could therefore be used as a test termination criterion. The subjects in this study were 160 coronary artery diseased (CAD) patients and 170 nondiseased individuals. Data were collected from existing stress test records. The R value was also analyzed to determine if proportions of diseased and nondiseased subjects were the same. The time it took 100 CAD patients to reach VO2 max and exhaustion once R rose above 1.00 was also examined.

The …

Effects Of Strengthening The Stabilizing Muscles Of The Hip Joint On Strength Gain Of The Hamstring Group, Tina M. Wilson

Masters Theses

The problem under investigation was to determine if strengthening the abductor and adductor muscle groups of the hip would increase hamstring flexion strength. Forty females from aerobic classes were put into two groups, control and treatment, after being pretested on the Cybex II Dynamometer. The control group participated only in aerobics, while the treatment group participated in the aerobics and treatment program. The treatment consisted of four exercises working abduction and adduction of the thigh with SPRI's Xercise Band.

After six weeks all subjects were posttested on the Cybex II Dynamometer. Both groups had significant increases in hamstring strength. These …

Total Blood Cholesterol, Blood Triglyceride, And Blood Hdl Correlation, Rebecca Lynn Babler

Masters Theses

The purpose of this investigation was to determine the relationship between total blood cholesterol levels, blood triglyceride levels, and blood HDL levels in men and women 20 to 80 years of age. All subjects fasted for 12 hours prior to having their blood drawn.

The computer program SPSSX (SPSSX, Inc., 1988) was used along with subprograms CONDESCRIPTIVE, CORRELATION, and ANOVA. Pearson Product Moment Correlations were calculated for all subjects, for male subjects, and for female subjects.

The study revealed a low correlation coefficient between blood cholesterol levels and blood triglyceride levels for all subjects, female subjects and male subjects. There …

The Effects Of Aerobic Conditioning Upon The Resting Metabolic Rate, Marti R. Davis

Masters Theses

This study com pared the metabolic rate following an exercise bout to the resting metabolic rate (RM R) established in pretesting procedures for twelve college age females. The only factor differentiating the groups was length o f the training period (one week, two weeks, four weeks, and five weeks). Training took place on a Bosch cycle ergometer three times a week, for 30 minutes each session, at 70 to 85 percent o f the subjects' heart rate reserve (HRR). Breath analysis was measured on a Beckman Metabolic Cart in both pretesting and post-testing procedures.

The findings indicated that aerobic exercise, …

A Biomechanical Analysis Of The Effect Wear Patterns Of Running Shoes Have On Kinematic Variables Of The Lower Extremities, Audrey E. Randall

Masters Theses

The purpose of the study was to investigate the relationship between wear patterns of running shoes and selected kinematic variables of the lower extremities. Statistical analyses were completed by using a case study design for two male subjects. Subjects were filmed for ten strides on six different sessions over a three-month period. A two-way ANOVA design, with repeated measures, evaluated the dependent variables: (a) footstrike, (b) midstance and (c) toeoff phases. The degree of change was determined by digitizing ten points on the body. A University of California, Los Angeles, BMDP2V statistical package was used to determine differences between means. …

The Effects Of Cigarette Smoking And Vitamin E On The Morphology Of Mice Testes, Kathleen Grams Hall

Masters Theses

Epidemiological studies have produced evidence to support an association between cigarette smoking and abnormal sperm morphology. At the least , an effect on sperm morphology indicates the involvement of the testis. Therefore, the research was designed to survey the potential of cigarette smoking for inducing histopathology in the testes of mice, and if there was damage, would vitamin E overcome it.

In the present study the testes of C57BL/6 mive exposed to cigarette smoke and/or vitamin E and 22 control mice were histologically processed. Sections stained with hematoxylin and eosin were assessed for total histopathology and revealed statistically significant differences …

Physiologic Responses To Maximal Exercise On A Treadmill, Monarch Bicycle Ergometer And Schwinn Air-Dyne Ergometer, Elaine Jason Naegele

Masters Theses

The study was conducted to determine which of three exercise modes would elicit the highest values for maximal oxygen uptake and maximal heart rate. Maximal graded exercise tests were performed by 20 healthy adults, ten women and ten men. Five of the women and five of the men were trained and the remaining ten were untrained. Each subject used, in a random order: (a) a motorized treadmill, (b) a Monarch bicycle ergometer, and (c) a Schwinn Air-Dyne ergometer. For each test, subjects were encouraged to complete successively harder workload stages, until they reached volitional exhaustion or localized muscle fatigue.

The …

The Effects Of Alprazolam And Triazolam On Two Methods Of Induced Aggression In Rats, Howard Kiel Plummer

Masters Theses

Two new benzodiazepine tranquilizers, alprazolam and triazolam were used to try to reduce aggression in rats produced by isolation or drugs. Both reduced elements of isolation-induced aggression, and triazolam was more potent. Little reduction was found in drug-induced aggression by either tranquilizer. It is unknown why aggression was not reduced for the drug-induced method, but it is possible that a synergism existed between the two methods of inducing aggression, since the same rats were used for both methods. Different rats were used for each tranquilizer. Reduction in aggression for the isolated rats seems consistent with results for other benzodiazepine tranquilizers.

Otopathology In Two Lines Of The Diabetic Chinese Hamster, Cricetulus Griseus, Jo A. Oostveen

Masters Theses

Recent evidence suggests that a bilateral, progressive sensorineural hearing loss is associated with diabetes mellitus in humans. The microangiopathy presumedly leading to this loss seems to be similar to microvascular changes leading to this loss seems to be similar to microvascular changes leading to renal and retinal deterioration. A total of twenty-four pairs of temporal bones from two diabetic, and one non-diabetic lines of the Chinese hamster were processed and evaluated for their total auditory histopathology. Hematoxylin and eosin serial sections demonstrated a mean otopathological involvement 5.6 times greater for diabetic animals compared to non-diabetic animals. Capillary basement membrane thickening …

The Induced Histopathology Of The Testes And Epididymides Of Cf-1 Mice By Known Or Suspected Teratogens, Mutagens, And Carcinogens, Kevin K. Block

Masters Theses

With each passing year, humans are exposed to ever increasing numbers of chemical agents, many of which may have mutagenic, carcinogenic, or teratogenic effects on the human species. Animal studies must be performed on any chemical substance that is suspected of being acutely dangerous to humans by way of cancer induction or inducted malformations to infants. Seven drugs of known or suspected mutagenic, carcinogenic, or teratogenic potential were examined for their ability to induce histopathology in the testes and epididymides of CF-1 mice. Mitomycin-C, hydroxyurea, and adriamycin induced significant histopathology whereas predisolone, thalidomide, streptomycin sulfate, and polybrominated biphenyl induced minimal …

The Effects Of Glucocorticoids On Gluconeogenesis In Diabetic And Normal Chinese Hamsters, Charles James Woody

Masters Theses

The objective of this study was to determine whether diabetic Chinese Hamsters maintained elevated endogenous cortisol concentrations and whether the previously reported elevation in gluconeogenesis in these diabetic animals was correlated with these cortisol concentrations.

It was found that nonketotic diabetic Chinese Hamsters maintained plasma cortisol concentrations similar to those of controls for the morning and evening time periods examined. Their rate of gluconeogenesis and absorption of injected pyruvate is much greater than that of controls in the morning. Furthermore, adrenalectomy increases gluconeogenesis and pyruvate absorption in both diabetics and normals and alleviates the difference seen in these parameters in …

The Effects Of Prostaglandin Synthesis Inhibition On The Regulation Of Blood Pressure In The Rat, David J. Pollock

Masters Theses

No abstract provided.

The Effects Of Hypophysectomy And Testosterone On Testicular Prostaglandin F2Α, Diane Charron Beuving

Masters Theses

No abstract provided.

Time-Related Changes In Rat Androgen Binding Protein Following A Sterilizing Dose Of 3-Chloro-1, 2-Propanediol, Shirley J. Stein

Masters Theses

Androgen binding protein (ABP) is produced by the Sertoli cell, regulated by FSH and androgens, secreted into the testicular fluid, and transported into the caput epididymis where it is thought to play a role in sperm maturation. In this study, the response of ABP to a lesion created chemically by administration of a single, oral 60 mg/kg dose of alpha-chlorohydrin was examined in ninety day old male rats. Total testicular ABP content increased progressively for four days after treatment and there after declined whereas, epididymal ABP concentration decreased immediately. Serum testosterone showed no significant variation from controls, however, serum FSH …

Prostaglandin E2: A Study Of Intestinal Secretion As A Mechanism Of Action For The Gastric Antisecretory Property In The Rat, Cleo Lancaster

Masters Theses

No abstract provided.

An In Vitro Study Of The Effects Of 17Β Estradiol On A Possible Atherosclerotic-Causing Enzyme, Xanthine Oxidase, Peter E. Malo

Masters Theses

No abstract provided.