Plant Sciences Commons^™

Understanding The Mechanisms Of Insecticide Resistance In Phlebotomus Papatasi And Lutzoymia Longipalpis Sand Flies (Diptera: Psychodidae: Phlebotominae), David Denlinger

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Sand flies, like mosquitoes, ticks, fleas, and lice, transmit pathogens that cause disease in humans. Leishmaniasis, caused by pathogens transmitted by sand flies, kills tens of thousands of people every year. Insecticides have been used to control sand flies, but there is evidence of insecticide resistance in populations of sand flies around the world. The goal of this dissertation was to develop tools to maintain sand flies in the laboratory, develop the ability to identify insecticide-resistant populations of sand flies, and to investigate the genetic mechanisms of how sand flies become resistant to insecticides. I began by comparing live animal …