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Effect Of Plant-Derived Molecules On Acinetobacter Baumannii Biofilm On Abiotic Surfaces, Ryan P. Pelletier

Honors Scholar Theses

The emergence of multiple drug resistant (MDR) Acinetobacter baumannii has lead to an increased interest in finding alternative antimicrobial compounds for controlling the pathogen. The present study investigated the effect of three plant-derived antimicrobials, namely eugenol (EUG), carvacrol (CAR), and thymol (THY), on A. baumannii biofilms. Using concentrations equal to or greater than the minimum bactericidal concentration (MBC) of each compound, the ability of EUG, CAR, and THY to inactivate the mature biofilms of three strains of MDR A. baumannii on polystyrene microtiter plates and stainless steel coupons was examined. All three plant-derived compounds significantly inactivated the bioflims of all …