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Full-Text Articles in Other Life Sciences
The Effect Of Wee1 On Mitosis In The Spb Mutant, David Leroy
The Effect Of Wee1 On Mitosis In The Spb Mutant, David Leroy
Honors Theses
The speedbump mutant has been identified as an early arrest mutant, becoming apparent as soon as 80% epiboly (8.5 hours of development). This mutant has a mutation in wee1, which is a protein regulating entry into mitosis ensuring the completion of DNA replication before mitosis. The lack of this protein in speedbump allows for early entry into mitosis resulting in damage to the chromosome. Here, we investigate two questions: if mitosis in the speedbump mutant phenotype is more frequent than wild-type phenotype, and, if so, is there a phase in which the mutant phenotype favors. We used phosphorylated histone H3 …
Bacteriophages That Can Lyse Antibiotic Resistant Bacteria, Michael Monaco
Bacteriophages That Can Lyse Antibiotic Resistant Bacteria, Michael Monaco
Honors Theses
A Klebsiella pneumoniae bacteriophage was isolated from waste water and purified over multiple rounds of plaque removals and serial titrations. This bacteriophage was imaged in a transmission electron microscope and then tested with selected antibiotics for effectiveness in reducing optical density of K. pneumoniae colonies. The phage was shown to have an increased effectiveness in reducing the optical density when used together with an antibiotic that the bacteria was susceptible to.