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High Fructose Corn Syrup Induces Metabolic Dysregulation And Altered Dopamine Signaling In The Absence Of Obesity, Allison M. Meyers, Devry Mourra, Jeff A. Beeler
High Fructose Corn Syrup Induces Metabolic Dysregulation And Altered Dopamine Signaling In The Absence Of Obesity, Allison M. Meyers, Devry Mourra, Jeff A. Beeler
Publications and Research
The contribution of high fructose corn syrup (HFCS) to metabolic disorder and obesity, independent of high fat, energy-rich diets, is controversial. While high-fat diets are widely accepted as a rodent model of diet-induced obesity (DIO) and metabolic disorder, the value of HFCS alone as a rodent model of DIO is unclear. Impaired dopamine function is associated with obesity and high fat diet, but the effect of HFCS on the dopamine system has not been investigated. The objective of this study was to test the effect of HFCS on weight gain, glucose regulation, and evoked dopamine release using fast-scan cyclic voltammetry. …