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Nutrition Commons

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Full-Text Articles in Nutrition

Consensus-Based Nutritional Recommendations For Patients With Head-And-Neck Cancer, Elizabeth Isenring Jul 2014

Consensus-Based Nutritional Recommendations For Patients With Head-And-Neck Cancer, Elizabeth Isenring

Liz Isenring

Extract: Patients with head-and-neck cancer constitute one of the diagnostic groups that most commonly experience deterioration of nutrition status. Malnutrition in patients with head-and-neck cancer is well known to potentially result in impaired wound healing, reduced immunocompetence, and decreased tolerance to treatment—and thus undesired treatment breaks and unplanned hospital admissions.


Effect Of Long Term Rapamycin Treatment On Mtor Signalling Network In Colon And Liver Of C57bl/6 Mice, John Sorge Jan 2014

Effect Of Long Term Rapamycin Treatment On Mtor Signalling Network In Colon And Liver Of C57bl/6 Mice, John Sorge

Wayne State University Theses

Many studies have investigated the effects of rapamycin on aging and cancer. However, the effects of long-term rapamycin supplementation on a cancer model have not been performed. This is the first study that investigates the effects of long-term supplementation of rapamycin in a cancer model. ACF analysis of colon tissues in mice showed no significant difference between controls and those supplemented with rapamycin. Factors such as energy balance, cellular environment, PI3K/Akt/mTOR pathway, and more have been assessed in this study. The duration of rapamycin supplementation seems to play an important role in the protection against cancer. Ultimately, this study suggests …


Effect Of Folate Deficiency On Mtor Signaling Network On The Liver Of Wild Type Mice, Essra Moussawi Jan 2014

Effect Of Folate Deficiency On Mtor Signaling Network On The Liver Of Wild Type Mice, Essra Moussawi

Wayne State University Theses

Through various studies of dietary nutrients on the affects of the physiological and molecular pathways are a key study in understanding the interaction between dietary nutrients and the human genome that may severely impact the development of various cancers. A primary approach is observing the dietary nutrients, that we consume and how it plays a role in the cellular pathway of our bodies through experimental methods. Folate deficiency (FD) has shown, through studies, to play a role anti-cancer progression. Our goal was to observe the autophagy related proteins in the mTOR signaling pathway as it was suggested that mTOR may …