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Molecular, Genetic, and Biochemical Nutrition
Faculty Publications & Research of the TUC College of Osteopathic Medicine
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Postprandial Paraoxonase 1 Activity Following Consumption Of Recommended Amounts Of Mixed Meals In Healthy Males, Noriko Kameyama, Chizuko Maruyama, Kazuhiko Kotani, Russell Caccavello, Alejandro Gugliucci, Sadako Matsui, Taro Maruyama
Postprandial Paraoxonase 1 Activity Following Consumption Of Recommended Amounts Of Mixed Meals In Healthy Males, Noriko Kameyama, Chizuko Maruyama, Kazuhiko Kotani, Russell Caccavello, Alejandro Gugliucci, Sadako Matsui, Taro Maruyama
Faculty Publications & Research of the TUC College of Osteopathic Medicine
Aim: Postprandial lipid level increases induce oxidative stress, which is involved in atherogenesis. The antioxidant properties of paraoxonase 1 (PON1) have attracted attention. However, changes in postprandial PON1 levels differ across prior studies, and changes in PON1 lactonase activity, potentially relevant to PON1 physiology, after the consumption of ordinary meals are unknown. Herein we evaluated postprandial serum lipid levels and PON1 changes following mixed-meal consumption of the amounts recommended for ordinary meals.
Methods: Nine healthy male volunteers consumed three different meals in a randomized cross-over design. The test meals were as follows: S, white rice; SMF, S with …