Nutrition Commons^™

Pkm2 Influences The Metabolic Fate Of Butyrate In Colorectal Cancer Cells, Megan Louise Pence

Chancellor’s Honors Program Projects

No abstract provided.

Cranberries And Cancer: An Update Of Preclinical Studies Evaluating The Cancer Inhibitory Potential Of Cranberry And Cranberry Derived Constituents, Katherine M. Weh, Jennifer L. Clarke, Laura A. Kresty

Department of Nutrition and Health Sciences: Faculty Publications

Cranberries are rich in bioactive constituents reported to influence a variety of health benefits, ranging from improved immune function and decreased infections to reduced cardiovascular disease and more recently cancer inhibition. A review of cranberry research targeting cancer revealed positive effects of cranberries or cranberry derived constituents against 17 different cancers utilizing a variety of in vitro techniques, whereas in vivo studies supported the inhibitory action of cranberries toward cancers of the esophagus, stomach, colon, bladder, prostate, glioblastoma and lymphoma. Mechanisms of cranberry-linked cancer inhibition include cellular death induction via apoptosis, necrosis and autophagy; reduction of cellular proliferation; alterations in …

Zhx2 Regulation Of Lipid Metabolism And The Balance Between Cardiovascular And Hepatic Health, Kate Townsend Creasy

Theses and Dissertations--Pharmacology and Nutritional Sciences

The growing obesity epidemic in America carries with it numerous health risks, including diabetes, increased serum lipid levels, and excess fat accumulation in the liver. If these conditions persist or become exacerbated, they may lead to the development of cardiovascular disease, the current leading cause of death among Americans, or to nonalcoholic fatty liver disease (NAFLD) which can progress to hepatocellular carcinoma (HCC), one of the deadliest forms of cancer. Better understanding of the genes involved in these diseases can lead to improved identification of at-risk individuals and treatment strategies.

Our lab previously identified zinc fingers and homeoboxes 2 (Zhx2) …