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Full-Text Articles in Laboratory and Basic Science Research

Relationship Between Morphogenesis And Secretion In The Filamentous Fungus Aspergillus Nidulans, Lakshmi Preethi Yerra Aug 2016

Relationship Between Morphogenesis And Secretion In The Filamentous Fungus Aspergillus Nidulans, Lakshmi Preethi Yerra

School of Biological Sciences: Dissertations, Theses, and Student Research

Filamentous fungi have a long history in biotechnology for the production of food ingredients, pharmaceuticals and enzymes. The advancements made in recent years have earned filamentous fungi such as Aspergillus species a dominant place among microbial cell factories. Although the model fungus A. nidulans has been extensively studied, the genetic and regulatory networks that underlie morphogenesis and development have yet to be fully characterized. The Rho GTPases (Cdc42 and RacA) are one of the most important regulators of the morphogenetic processes among diverse eukaryotic organisms. Although the functions of these GTPases are relatively well-characterized, little is known about their downstream …


Non-Essentiality Of Alr And Muri Genes In Mycobacteria, Philion L. Hoff, Denise Zinniel, Raúl G. Barletta Apr 2016

Non-Essentiality Of Alr And Muri Genes In Mycobacteria, Philion L. Hoff, Denise Zinniel, Raúl G. Barletta

UCARE Research Products

Amino acids are the building blocks of life. If DNA is the blueprint, amino acids are the lumber that proteins are built with. Proteins are built with left-handed, L- forms of amino acids. Bacteria have an essential cell wall component that happens to be an exception: peptidoglycan. Bacteria have enzymes called racemases that convert L- amino acid forms into right-handed, D- forms. Amino acids participate in many reactions with keto acids. Transaminases allow conversion between amino acids by transfer of an amino group.

Previous reports claimed there is no D-ala transaminase activity in mycobacteria and thus alr and murI genes …


How Nebraska’S Eastern Saline Wetland Native Plant Species Grow In Response To Restoration Methods: Application Of Different Salinity Level Groundwater, Ellen Dolph, Keunyea Song, Amy Burgin, Trenton E. Franz Apr 2016

How Nebraska’S Eastern Saline Wetland Native Plant Species Grow In Response To Restoration Methods: Application Of Different Salinity Level Groundwater, Ellen Dolph, Keunyea Song, Amy Burgin, Trenton E. Franz

UCARE Research Products

Nebraska’s Eastern Saline Wetlands are unique ecosystems endemic to the Salt and Rock Creek waters in Lancaster and Saunders County.

They provide an ecosystem services as well as habitat for endangered species such as the state endangered saltwort (Salicornia rubra) and federally endangered Salt Creek tiger beetle (Cicindela nevadica lincolniana).

Over 80 % of the saline wetlands are highly degraded and in recent years, the Saline Wetland Conservation Partnership has formed to conserve and restore the remaining saline wetland fragments, but there is limited information about inland saline wetland restoration. Purpose: Investigate techniques to better conserve …


Privatization Of Biomedical Research: A Short Term Answer With Long Term Consequences, Frederick Azalekor Jan 2016

Privatization Of Biomedical Research: A Short Term Answer With Long Term Consequences, Frederick Azalekor

Nebraska College Preparatory Academy: Senior Capstone Projects

Biomedical research owned by the government is now available to be owned by private institutions. This results in stagnant innovations because researchers have trouble with all the restrictions that are placed by private institutions. Privatization of biomedical research has short term positive effects but its negative effects are overarching and disastrous. One way to combat this, is for licenses to be deployed slowly with future consequences in mind.

• Privatization has short term benefits but long term disadvantages are disastrous. • To reduce damaging effect, privatization must be deployed slowly and carefully. • Patents or proprietary ownership must be given …