Open Access. Powered by Scholars. Published by Universities.®

Laboratory and Basic Science Research Commons™

Open Access. Powered by Scholars. Published by Universities.®

Animal Sciences

Theses/Dissertations

2016

Articles 1 - 2 of 2

Full-Text Articles in Laboratory and Basic Science Research

Influencing Pathways That Cause Metastasis And Stemness In Epithelial Ovarian Cancer, Alyse Lynn Huisken-Hill Jun 2016

Influencing Pathways That Cause Metastasis And Stemness In Epithelial Ovarian Cancer, Alyse Lynn Huisken-Hill

Electronic Theses, Projects, and Dissertations

Ovarian cancer is the fifth leading cause of cancer death in women between the ages of 35 and 74. With 22 thousand new cases and 15 thousand deaths annually ovarian cancer is among the most deadly cancers with a death to incidence ratio of 68%. With 70% of cases High Grade Serous Ovarian Carcinoma (HGSOC) is the most common type of ovarian cancer and causes 90% of ovarian cancer deaths. 80% of patients have reoccurrence within five years and only 15-30% of patients with recurrent metastatic ovarian cancer respond to current therapies, chemotherapy and surgery. One reason for the high …

Go to article

Sources Of Ecologically Important Trait Variation In Mosquitofish (Gambusia Affinis And Gambusia Holbrooki), Heather Ann Arnett Apr 2016

Sources Of Ecologically Important Trait Variation In Mosquitofish (Gambusia Affinis And Gambusia Holbrooki), Heather Ann Arnett

Electronic Theses and Dissertations

The study of contemporary evolution and eco-evolutionary dynamics is classically defined in terms of genetic evolution, but the actual suite of processes driving contemporary trait change is likely much more complex than often credited. This dissertation considers additional mechanisms of trait change that might be important to an emerging model system for study of contemporary evolution and eco-evolutionary dynamics. Specifically, the research focuses on phenotypically plastic and demographic trait variation in Eastern and Western Mosquitofish (Gambusia affinis and G. holbrooki) facing the major ecological gradient of predation risk. Plasticity experiments employed a common-garden rearing design to manipulate fish …

Go to article