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Open Access. Powered by Scholars. Published by Universities.®

2010

Physical Sciences and Mathematics

ICOCO2010

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Full-Text Articles in Biotechnology

Optimal Control Of A Switched System In Microbial Fed-Batch Fermentation Process, Chongyang Liu, Zhaohua Gong, Enmin Feng Jul 2010

Optimal Control Of A Switched System In Microbial Fed-Batch Fermentation Process, Chongyang Liu, Zhaohua Gong, Enmin Feng

Chongyang Liu

The main control goal in fed-batch fermentation process is to get a high concentration of production. In this paper, by taking the feed rate of glycerol as the control function, a nonlinear switched system is proposed to formulate the fed-batch fermentation process of glycerol to 1,3-propanediol (1,3-PD). To maximize the concentration of 1,3-PD at the terminal time, an optimal switching control model subject to constraints of continuous state inequality and control function is presented. A computational approach is developed to seek the optimal solution in two aspects. On the one hand, the control parametrization enhancing transform together with the control …