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Gas-Based Perfusion Fmri Cerebrovascular Reactivity Maps And Time Of Arrival Maps, Jinxia Yao, Yunjie Tong, Matthew Robert Derdak

The Summer Undergraduate Research Fellowship (SURF) Symposium

Perfusion MRI is a promising tool used in assessing stroke, brain tumors, and patients with neurodegenerative diseases. However, common perfusion MRI techniques have several disadvantages, such as using exogenous contrast agents, low signal-to-noise ratio and long acquisition time. In this study, we used a computer-controlled gas delivery system RespirAct TM. This system provides a reliable carbon dioxide based vasoactive stimulus. This stimulus will immediately generate large and reliable functional magnetic resonance imaging (fMRI) signals, which can be used for perfusion imaging. Each subject was required to have three sequential magnetic resonance imaging (MRI) scans, which are structural scan, resting state …