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Articles 1 - 30 of 35
Full-Text Articles in Life Sciences
Engaging Students In A Genetics Course-Based Undergraduate Research Experience Utilizing Caenorhabditis Elegans In Hybrid Learning To Explore Human Disease Gene Variants, Natalie Forte, Virginia Veasey, Bethany Christie, Amira Carter, Marli Hanks, Alan Holderfield, Taylor Houston, Anil Challa, Ashley Turner
Engaging Students In A Genetics Course-Based Undergraduate Research Experience Utilizing Caenorhabditis Elegans In Hybrid Learning To Explore Human Disease Gene Variants, Natalie Forte, Virginia Veasey, Bethany Christie, Amira Carter, Marli Hanks, Alan Holderfield, Taylor Houston, Anil Challa, Ashley Turner
Research, Publications & Creative Work
Genetic analysis in model systems using bioinformatic approaches provides a rich context for a concrete and conceptual understanding of gene structure and function. With the intent to engage students in research and explore disease biology utilizing the nematode Caenorhabditis elegans model, we developed a semester-long course-based undergraduate research experience (CURE) in a hybrid (online/in-person) learning environment—the gene-editing and evolutionary nematode exploration CURE (GENE-CURE). Using a combination of bioinformatic and molecular genetic tools, students performed structure-function analysis of disease-associated variants of uncertain significance (VUS) in human orthologs. With the aid of a series of workshop-style research sessions, students worked in teams …
Gaming To Learn Genetics, Sarah Wolfe
Gaming To Learn Genetics, Sarah Wolfe
Undergraduate Honors Thesis Projects
Digital game-based learning is an alternative to traditional lecture learning. It involves active engagement with concepts in a digital game setting and can apply to a variety of subjects, including STEM fields. We examined this type of learning in the context of an undergraduate introductory genetics course: specifically, use of a genetics video game for teaching. There were two groups: an experimental group that played the genetics game Geniventure, and a control group that read and studied Powerpoint lecture slides. Both groups took a pretest and posttest, as well as completed an I/D (interest/deprivation) scale and workload scale. There …
Utilizing Markov Chains To Estimate Allele Progression Through Generations, Ronit Gandhi
Utilizing Markov Chains To Estimate Allele Progression Through Generations, Ronit Gandhi
Honors Theses
All populations display patterns in allele frequencies over time. Some alleles cease to exist, while some grow to become the norm. These frequencies can shift or stay constant based on the conditions the population lives in. If in Hardy-Weinberg equilibrium, the allele frequencies stay constant. Most populations, however, have bias from environmental factors, sexual preferences, other organisms, etc. We propose a stochastic Markov chain model to study allele progression across generations. In such a model, the allele frequencies in the next generation depend only on the frequencies in the current one.
We use this model to track a recessive allele …
Strategic Plan For Genomic Competencies Into Undergraduate Nursing Curriculum, Myerann Royce M. Mangalino
Strategic Plan For Genomic Competencies Into Undergraduate Nursing Curriculum, Myerann Royce M. Mangalino
UNLV Theses, Dissertations, Professional Papers, and Capstones
Problem: As genomics research continues to grow in medicine and in popular culture, an educational gap in nursing is inevitable. Nurses must have a strong understanding of genetics and genomics to effectively integrate them into current practice.Objectives: The objective is to identify gaps in the current undergraduate curriculum and build threads that may be incorporated into the current curriculum to fill the identified gaps. Methods: The foundation of this project was the Essentials of Genetic and Genomic Nursing: Competencies, Curricula Guidelines, and Outcome Indicators, 2nd Edition (Consensus Panel on Genetic/Genomic Nursing Competencies, 2008). A strategic plan was created to increase …
Genetics And Genomics Education Among Physician Assistants, Wesley Patterson
Genetics And Genomics Education Among Physician Assistants, Wesley Patterson
All Dissertations
This dissertation comprises five chapters to describe genetics and genomics education among physician assistant/associate (PA) students and practicing PAs. Chapter I introduces the gap in supply and demand of genetic services, the need for non-genetics healthcare providers to fill the gap, and the PA profession as a solution.
Chapter II is a rapid literature review that summarizes the available literature regarding genetics and genomics education for PAs. A paucity of literature exists to describe the current state of PA genetics-genomics education. The few studies retrieved describe content being taught in PA programs, the number of genetics-genomics contact hours PA students …
Mhc Diversity Analysis Of Spheniscus Demersus For In Situ And Ex Situ Populations, Antonieta Van Den Berg Monsalve
Mhc Diversity Analysis Of Spheniscus Demersus For In Situ And Ex Situ Populations, Antonieta Van Den Berg Monsalve
Undergraduate Honors Thesis Projects
The South African Penguin has been listed as endangered by the International Union for Conservation of Nature. Major histocompatibility complex (MHC) alleles provide valuable statistics because of their variation in terms of vertebrate genomes and are pertinent to immune and reproductive health. A greater number of MHC alleles correlates with survivability of a population because the genes control the immune and reproductive systems. Legacy research by Otterbein alumni and Dr. Simon Lawrance studied MHC samples from wild, in situ, and captive, ex situ, penguin populations. By comparing these populations' major histocompatibility complexes through biostatistical analysis, contributions to conservation of the …
A Timeline Of Discovery And Current Research On Primary Open-Angle Glaucoma And Emergence Of Potentially Permanent Treatment Solutions, Yonosuke Dejesus, Guadalupe Moreno Ceballos
A Timeline Of Discovery And Current Research On Primary Open-Angle Glaucoma And Emergence Of Potentially Permanent Treatment Solutions, Yonosuke Dejesus, Guadalupe Moreno Ceballos
Spectra Undergraduate Research Journal
This research examines the timeline of the discovery and research of Primary Open-Angle Glaucoma (POAG). By reviewing the literature on genetic and molecular mechanisms, we aim to emphasize a long-term treatment solution (iSTENT) to mitigate intraocular pressure (IOP) related to POAG etiology and disease progression. POAG is a multifactorial, autosomal dominant, adult-onset eye disease wherein the optic nerve cells become damaged due to a buildup of excess aqueous humor, resulting in increased IOP. Consequently, POAG leads to progressive loss of peripheral vision and is the leading cause of blindness in the US. Due to the multifactorial nature of glaucoma’s inheritance …
A Strategic Plan To Thread Genomics Competencies Into Undergraduate Curriculum, Holly Mathis
A Strategic Plan To Thread Genomics Competencies Into Undergraduate Curriculum, Holly Mathis
Dissertations
Problem: Genomics in undergraduate nursing education has experienced slow adoption in the United States. Various approaches have been proposed but do not address barriers to successful implementation.
Methods: A strategic plan was developed to increase the amount of genetics and genomic content in the curriculum of an undergraduate nursing program. A gap analysis was performed on the curriculum revealing a paucity of content. A SWOT analysis informed the strategic plan, which included a faculty education program using the ANA/ISONG’s Essentials of Genetic and Genomic Nursing: Competencies, Curricula Guidelines and Outcome Indicators (2nd ed.) (2009) as a foundation.
Results: Faculty …
The Embark® Protocol: Dog Genomics In Genetics Laboratories, Alexandra Kissel
The Embark® Protocol: Dog Genomics In Genetics Laboratories, Alexandra Kissel
Honors Theses
In a world of ever-advancing technology, it is imperative that young pre-health professionals are educated according to the most relevant research. One of the most fundamental, foundational concepts of health is genetics. This field is rapidly expanding, and quickly engraining itself into the realm of healthcare. Genetic testing and gene therapies, once subjects of science fiction, have become commonplace. It is more important than ever that health professionals have a concrete knowledge of genetics, and this begins with the proper education of pre-health students.
With this idea in mind, a laboratory protocol was designed for students of the Bisc 336 …
Genetics With Nettie And Friends: An Exploration Of Genetics In Children's Literature, Erin Soule, Madeleine Gray Burland
Genetics With Nettie And Friends: An Exploration Of Genetics In Children's Literature, Erin Soule, Madeleine Gray Burland
Honors Projects
Genetics with Nettie and Friends is an exploration of chromosomal disorders and its place within children's literature. The book provides a comprehensive examination the genetic composition of Downs syndrome, Williams Syndrome, and Duchenne muscular dystrophy at a level to increase understanding in children. This paper provides an insight to the development and construction of the children's book that is available for purchase on Barnes and Noble as well as why representation of genetic disorders in children's literature is needed.
Evidence-Based Practice Self-Study Education Program For Staff Nurses On Genomics, Nancy L. Norman-Marzella
Evidence-Based Practice Self-Study Education Program For Staff Nurses On Genomics, Nancy L. Norman-Marzella
Walden Dissertations and Doctoral Studies
Nurses routinely obtain genomic data when collecting family health histories. However, they report low confidence in their knowledge and understanding of genomics and the genetically engineered medications prescribed for their patients. The purpose of this project was the development and implementation of an evidence-based online education program about genetics and genomics to increase the nurses' understanding and ability to provide competent care for their patients receiving treatments based on the science of genomics. Knowles's principles of adult learning theory guided the development and delivery of the online education project to 12 medical-surgical registered nurses employed in a hospital in the …
Bois 412/812: Human Genetics—A Peer Review Of Teaching Project Benchmark Portfolio, Colin D. Meiklejohn
Bois 412/812: Human Genetics—A Peer Review Of Teaching Project Benchmark Portfolio, Colin D. Meiklejohn
UNL Faculty Course Portfolios
This portfolio focuses on Human Genetics, an upper-division course taken primarily by biology majors to fulfill elective credit in their degree. This course studies the genetic basis for human variation, with the goal of placing this variation in the context of human evolutionary history and the consequences of this variation for medical understanding and treatments. In Human Genetics, students complete an original synthetic research paper on a human genetic disorder. Through writing this paper, students are expected to learn how to navigate electronic databases and online resources on human genetic diseases, and to read and synthesize the primary scientific literature. …
Parentage Analysis And Conservation Genetics Educational Material For The Eastern Hellbender Salamander, Cryptobranchus Alleganiensis Alleganiensis, Sarah A. Chudyk
Parentage Analysis And Conservation Genetics Educational Material For The Eastern Hellbender Salamander, Cryptobranchus Alleganiensis Alleganiensis, Sarah A. Chudyk
Master's Projects
Populations of the Eastern hellbender salamander, Cryptobranchus alleganiensis alleganiensis, are declining, making this a species of special concern in New York State and under consideration for Federal Endangered Species listing. As a result of this decline, the New York State Department of Environmental Conservation and the Buffalo Zoo initiated a headstarting program with an egg mass found in the Allegheny River drainage. The juveniles being raised by the Zoo will be released back into the watershed and so understanding the genetic diversity and parentage of these hellbenders will inform the reintroduction efforts. Furthermore, in order to determine how to …
Engaging Students In A Bioinformatics Activity To Introduce Gene Structure And Function, Barbara J. May
Engaging Students In A Bioinformatics Activity To Introduce Gene Structure And Function, Barbara J. May
Biology Faculty Publications
Bioinformatics spans many fields of biological research and plays a vital role in mining and analyzing data. Therefore, there is an ever-increasing need for students to understand not only what can be learned from this data, but also how to use basic bioinformatics tools. This activity is designed to provide secondary and undergraduate biology students to a hands-on activity meant to explore and understand gene structure with the use of basic bioinformatic tools. Students are provided an “unknown” sequence from which they are asked to use a free online gene finder program to identify the gene. Students then predict the …
Mathematical Manipulative Models: In Defense Of "Beanbag Biology", John R. Jungck, Holly Gaff, Anton E. Weisstein
Mathematical Manipulative Models: In Defense Of "Beanbag Biology", John R. Jungck, Holly Gaff, Anton E. Weisstein
Biological Sciences Faculty Publications
Mathematical manipulative models have had a long history of influence in biological research and in secondary school education, but they are frequently neglected in undergraduate biology education. By linking mathematical manipulative models in a four-step process-1) use of physical manipulatives, 2) interactive exploration of computer simulations, 3) derivation of mathematical relationships from core principles, and 4) analysis of real data sets-we demonstrate a process that we have shared in biological faculty development workshops led by staff from the BioQUEST Curriculum Consortium over the past 24 yr. We built this approach based upon a broad survey of literature in mathematical educational …
The Ethical Phenomenon Of Gm-Corn: Anger, Anxiety, And Arrogance In Crossing American Borders, Jules Simon
The Ethical Phenomenon Of Gm-Corn: Anger, Anxiety, And Arrogance In Crossing American Borders, Jules Simon
Jules Simon
In terms of phenomenology, I often wonder about the relevance of what I do as a philosopher for the life of those with whom I come into contact. This ‘coming into contact’ happens for me on several levels: as one human among many, as a husband and father and son and brother, as a teacher, as a neighbor, and as country or city dweller. I remember with fondness those times in the late sultry summer months when, as a youth, I would drive with my father to this or that local farm-stand on some remote back road in the hills …
2008 Nebraska Beef Cattle Report Summaries, Richard J. Rasby, Galen E. Erickson, Dennis R. Brink
2008 Nebraska Beef Cattle Report Summaries, Richard J. Rasby, Galen E. Erickson, Dennis R. Brink
University of Nebraska-Lincoln Extension: Historical Materials
Reports on recent beef research are briefly summarized in this publication. Summaries of the research featured in the 2008 Beef Report appear here. Topics include cow-calf, growing, finishing and beef products.
Are You What You Eat? An Inside Look At High-Tech Food, Roxanne Greitz Miller
Are You What You Eat? An Inside Look At High-Tech Food, Roxanne Greitz Miller
Education Faculty Articles and Research
If we abide by the familiar saying "you are what you eat," it is understandable that people may be concerned with the incredible advances in food science technology and their possible impacts on human health. For example, in recent years high-tech scientific processes such as genetic modification, irradiation, and cloning have all been used to increase the safety of food supply, create foods that are more appealing to eat and easier to produce, and increase crop yields. This article will summarize a few hot topics in food science, address what is currently known about the safety of these processes, and …
2006 Nebraska Swine Report, Duane E. Reese
2006 Nebraska Swine Report, Duane E. Reese
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, breeding, health, nutrition, genetics, economics and housing of swine.
2005 Nebraska Swine Report, Duane E. Reese
2005 Nebraska Swine Report, Duane E. Reese
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, breeding, health, genetics, nutrition, economics and housing of swine.
2003 Nebraska Swine Report, Duane E. Reese
2003 Nebraska Swine Report, Duane E. Reese
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, breeding, health, genetics, nutrition, economics and housing of swine.
2002 Nebraska Swine Report, Duane E. Reese
2002 Nebraska Swine Report, Duane E. Reese
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, breeding, health, nutrition, economics and housing of swine.
2001 Nebraska Swine Report, Duane E. Reese
2001 Nebraska Swine Report, Duane E. Reese
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, breeding, health, nutrition, economics and housing of swine.
2000 Nebraska Swine Report, Rodger K. Johnson
2000 Nebraska Swine Report, Rodger K. Johnson
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, breeding, health, nutrition, economics and housing of swine.
1999 Nebraska Swine Report, Duane E. Reese
1999 Nebraska Swine Report, Duane E. Reese
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, genetics, breeding, health, nutrition, economics and housing of swine.
G95-1271 Mastitis Is A Disease -- Control Is An Everyday Task, Gerald R. Bodman, Duane N. Rice
G95-1271 Mastitis Is A Disease -- Control Is An Everyday Task, Gerald R. Bodman, Duane N. Rice
University of Nebraska-Lincoln Extension: Historical Materials
A comprehensive mastitis control program will effectively control infections caused by both environmental and contagious pathogens.
Herd mastitis problems can be caused by both environmental and contagious pathogens (disease-causing organisms). These problems may occur separately or simultaneously. Various testing techniques are necessary to determine the type of causative organism and the infection level of the herd or individual cow. Appropriate tests include the CMT (California Mastitis Test), milk market somatic cell count (SCC), Dairy Herd Improvement Association (DHIA) SCC and laboratory cultures of milk from infected cows. Depending upon test results, mastitis control strategies may need to be changed to …
G94-1197 The Genetics And Management Of Sound Feet And Legs, Jeffrey F. Keown
G94-1197 The Genetics And Management Of Sound Feet And Legs, Jeffrey F. Keown
University of Nebraska-Lincoln Extension: Historical Materials
Sound management of feet and legs in dairy animals affects performance. This guide offers suggestions for good management practices.
Two major parameters affect the selection process for any trait: the heritability of the trait as well as the variation associated with the trait.
Charles Birch: Synthesis And Hope, Rowan Cahill
Charles Birch: Synthesis And Hope, Rowan Cahill
Rowan Cahill
Mp92-64 The Stable Fly: A Pest Of Humans And Domestic Animals, Gustave D. Thomas, Steven R. Skoda
Mp92-64 The Stable Fly: A Pest Of Humans And Domestic Animals, Gustave D. Thomas, Steven R. Skoda
University of Nebraska-Lincoln Extension: Historical Materials
Many species of flies are pests. Many people, if you were to ask them about flies, would be at least vaguely aware of the potential to flies to transmit disease organisms. But yet, for the most part, a fly is a fly is a fly. Sayings like "It must be about to rain, the house flies are biting" are still common and show a general need for more, readily accessible information, particularly about some of the pest flies.
Stable flies, obligate blood-feeders, are very important pests to the cattle industry and, at times, are pests to other groups (they're most …
G89-989 How To Interpret The New Animal Model For Dairy Sire Evaluation, Jeffrey F. Keown
G89-989 How To Interpret The New Animal Model For Dairy Sire Evaluation, Jeffrey F. Keown
University of Nebraska-Lincoln Extension: Historical Materials
In question and answer format this NebGuide addresses changes in genetic evaluations of both dairy cows and sores.
Why is the United States Department of Agriculture (USDA) changing the dairy sire and cow evaluation system?
The answer is simple. The Animal Model for genetic evaluations is more accurate than the old Modified Contemporary Comparison Method (M.C.C.). Previously the major limiting factors to implementing the Animal Model were computing costs and memory requirements. With the advent of new Super Computers, the computations are feasible on a national scale.
What is the Animal Model?
The Animal Model simultaneously evaluates cows and sires …