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Life Sciences Commons

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2021

Journal

The Science Journal of the Lander College of Arts and Sciences

Metformin

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Full-Text Articles in Life Sciences

Rapamycin And Metformin In Treating Covid-19, Avrohom Karp Jan 2021

Rapamycin And Metformin In Treating Covid-19, Avrohom Karp

The Science Journal of the Lander College of Arts and Sciences

The SARS-CoV-2 virus has spread rapidly, resulting in a global pandemic. There is a great need for an effective drug cocktail therapy to combat Acute Respiratory Distress Syndrome (ARDS), a major cause of death due to COVID-19. The two drugs examined are metformin, an antidiabetic medication, and rapamycin. Rapamycin is often prescribed for transplant patients as it has an immunosuppressive effect. The aim of the investigation was to determine the efficacy of metformin and rapamycin in treating COVID-19, and to examine what an effective protocol would look like. These two drugs both inhibit mTOR and can reduce the body’s auto-immune …