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2021

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Research Day

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The Mind-Body Connection: Exploring The Defining Characteristics Of Two Aging Phenotypes, Kiyana Harris, Xue-Lian Sun, Mei-Ling Ge, Qian-Li Xue May 2021

The Mind-Body Connection: Exploring The Defining Characteristics Of Two Aging Phenotypes, Kiyana Harris, Xue-Lian Sun, Mei-Ling Ge, Qian-Li Xue

Research Day

Introduction: Built on the theory of mind-body connection, there has been a growing interest in phenotypes combining physical frailty and cognitive decline. Two examples are motoric cognitive risk syndrome (MCR) and cognitive frailty (CF). MCR, defined by co-presentation of slow gait and subjective cognitive complaint without dementia or mobility disability, is considered a “pre-dementia syndrome.” CF, defined as having both physical frailty and cognitive impairment in the absence of dementia, is posited to be caused by physical frailty. Although both MCR and CF have been associated with dementia risk, the relationship between the two is unknown. We aimed to (1) …