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Full-Text Articles in Life Sciences
Very Low-Carbohydrate, High-Fat, Weight Reduction Diet Decreases Hepatic Gene Response To Glucose In Obese Rats, Kathleen V. Axen, Marianna A. Harper, Yu Fu Kuo, Kenneth Axen
Very Low-Carbohydrate, High-Fat, Weight Reduction Diet Decreases Hepatic Gene Response To Glucose In Obese Rats, Kathleen V. Axen, Marianna A. Harper, Yu Fu Kuo, Kenneth Axen
Publications and Research
Background: Very low carbohydrate (VLC) diets are used to promote weight loss and improve insulin resistance (IR) in obesity. Since the high fat content of VLC diets may predispose to hepatic steatosis and hepatic insulin resistance, we investigated the effect of a VLC weight-reduction diet on measures of hepatic and whole body insulin resistance in obese rats.
Methods: In Phase 1, adult male Sprague-Dawley rats were made obese by ad libitum consumption of a high-fat (HF1, 60% of energy) diet; control rats ate a lower-fat (LF, 15%) diet for 10 weeks. In Phase 2, obese rats were fed energy-restricted amounts …
Relationship Between “A Body Shape Index (Absi)” And Body Composition In Obese Patients With Type 2 Diabetes, Fernando Gomez-Peralta, Cristina Abreu, Margarita Cruz-Bravo, Elvira Alcarria, Gala Gutierrez-Buey, Nir Y. Krakauer, Jesse C. Krakauer
Relationship Between “A Body Shape Index (Absi)” And Body Composition In Obese Patients With Type 2 Diabetes, Fernando Gomez-Peralta, Cristina Abreu, Margarita Cruz-Bravo, Elvira Alcarria, Gala Gutierrez-Buey, Nir Y. Krakauer, Jesse C. Krakauer
Publications and Research
Background: Obesity is known to be related to the development of type 2 diabetes mellitus (T2D). The most commonly used anthropometric indicator (body mass index [BMI]) presents several limitations such as the lack of possibility to distinguish adipose tissue distribution. Thus, this study examines the suitability of a body shape index (ABSI) for prediction of body composition and sarcopenic obesity in obese or overweight T2D subjects.
Methods: Cross-sectional study in 199 overweight/obese T2D adults. Anthropometric (BMI, ABSI) and body composition (fat mass [FM], fat-free mass [FFM], fat mass index [FMI] and fat-free mass index, and the ratio FM/FFM as an …