Life Sciences Commons^™

Density, Growth, And Reproduction Of The Cockle Laevicardium Mortoni In The Peconic Bays, Long Island, New York, Hailey Brosnan

Post & Beyond

Morton’s egg cockle, Laevicardium mortoni, is common in shallow subtidal

habitats from Nova Scotia to Brazil, but little is known of its biology and ecology.

Field studies were conducted in the Peconic Bays of Long Island, New

York to examine population and life history parameters such as density,

growth, and age at first reproduction. Suction dredging was conducted at

three sites to examine whether density varied with depth and sediment

type. Condition Indexes for a range of cockle sizes were quantified weekly

at two sites to estimate age and size at first reproduction. Growth rates and

temporal patterns of …

Newest Kid On The Block: Characterization Of The Novel Multidrugresistant Pathogen, Candida Auris, Lindsey Masone, Susanna Mirabelli

Post & Beyond

Candida auris is a novel and emerging fungal pathogen capable of causinginvasive, and often fatal, bloodstream and wound infections in immunocompromised patients. Several outbreaks have been reported in hospitals across the world, including the United States, and predominantly in New York. C.auris exhibits extensive multidrug resistance that has never been seen in any Candida species, and is often misdiagnosed for other Candida species, thus limiting treatment options for patients. Our laboratory obtained 10 C. auris isolates in order to perform in vitro antifungal susceptibility testing and determine the Minimum Inhibitory Concentration (MIC) under Clinical and Laboratory Standards Institute guidelines. …

Chromatin Condensation Protects Dna From Mms Damage, Sherwin Shaju

Post & Beyond

Chromatin is the complex of proteins and DNA that makes up eukaryotic

chromosomes. Chromatin helps the DNA fit inside the nucleus as well as

regulating what can access the DNA. Replication, repair, and transcription

are all impeded by chromatin. These processes only occur efficiently

when chromatin is disassembled. Just as chromatin limits how proteins

can access the DNA, we hypothesized that it would also protect DNA. We

used the yeast Saccharomyces cerevisiae to study how chromatin affects

cellular sensitivity to the DNA alkylating agent methyl methanesulfonate

(MMS). MMS alkylation can lead to DNA mismatches, nicks, and double

strand breaks, resulting …

Background, Needs And Expectations For Genetic Counseling In Adults With Ehlers-Danlos Syndrome, Pooja Swaroop

Post & Beyond

Ehlers-Danlos Syndrome (EDS) is a heterogeneous group of heritable connective

tissue disorders. Patients with EDS often show a wide range of

clinical manifestations, which most often include joint hypermobility, connective

tissue fragility and skin hyperextensibility. The symptomatology of

individuals with EDS-Hypermobile Type (EDS-HT) is complex and can range

in severity from mild to profound with several studies reporting multisystem

involvement. In addition to the aforementioned symptoms, there

is a significant risk for comorbid psychiatric disorders. Currently, genetics

professionals and genetic counselors act primarily as diagnosticians and

provide tertiary support for the ongoing care, coordination and management

of patients with EDS. …

Age And Size At First Reproduction In The Channeled Whelk Population Of The Great South Bay, Long Island, New York., Robin Lynn

Post & Beyond

The channeled whelk, Busycotypus canaliculatus, is a commercially valuable gastropod found on the east coast of the United States. In New York, the channeled whelk fishery is largely unregulated, due to a lack of knowledge regarding the life history of the species. This study focuses on determining the age and size at first reproduction of the channeled whelk population in the Great South Bay, on the southern shore of Long Island. Whelks were obtained from a commercial fisherman and individually dissected to determine maturity; correlations to shell length and shell width were then examined. The operculum of each individual dissected …

Where Is The Nls In Tip60?, Himali Vashishtha

Post & Beyond

Tip60 is a lysine acetyltransferase (KAT), coded by the KAT5 gene, which is involved in transcription, DNA repair, and apoptosis. It acetylates histones, the ATM protein kinase, and the p53 tumor suppressor, among other targets, making it a key regulator of cell homeostasis. Tip60 has been shown to be a tumor suppressor in most cancers but an oncogene in prostate cancer. Some of Tip60’s functions take place in the nucleus while others occur in the cytoplasm. We were interested in investigating whether the nuclear localization of Tip60 is important for its tumor suppressor function. We hypothesized that decreasing Tip60 nuclear …

Seroprevalence Of Babesia Microti In Patients With Lyme Disease, Sabino Curcio

Post & Beyond

Babesiosis is a tickborne disease caused by Babesia microti, an intracellular parasite of red blood cells. Presently, B. microti is the most common and deadly pathogen transmitted by blood transfusion. B. microti infects humans via Ixodes scapularis ticks, the same vector carrying Borrelia burgdorferi, the causative agent of Lyme disease. Co-infection with these two diseases increases the severity of symptoms, posing a major therapeutic challenge. We aimed to determine the co-infection rate of B. microti in individuals who tested positive for Lyme disease. Sera obtained from 154 individuals in New York State were collected and tested by immunofluorescence assay. Of …