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Open Access. Powered by Scholars. Published by Universities.®

2008

Al-Azhar Bulletin of Science

MICROCAPSULES; Agarose gel

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Synthesis Of New Microcapsules From Agarose Gel And Their Medical Applications, Ashraf Seida, Ezz El-Gamal, Mahmoud Gabr, Hassan Ibrahim, Mohamed El-Gharib Jun 2008

Synthesis Of New Microcapsules From Agarose Gel And Their Medical Applications, Ashraf Seida, Ezz El-Gamal, Mahmoud Gabr, Hassan Ibrahim, Mohamed El-Gharib

Al-Azhar Bulletin of Science

Prevention of rejection is critical to achieve successful pancreatic islet transplantation protection of islet cells from rejection by isolating the islets in artificial membranes has been used instead of immunosuppression treatment. In these study we investigated the microencapsulation of microencapsulated hamster islets in hydrophilic microencapsules made of agarose. The microencapsulated hamster islets were placed interaperitoneally in mice in which diabetes was induced by a single dose (150 mg/kgof body weight) of streptozotocin. Five groups were studied. The first group (5 mice) received free hamster islets (1000 islets).The second group (5 mice) received 1000 empty agarose microcapsules and 1000 free hamster …