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Full-Text Articles in Life Sciences
Friend Of The Good Earth: [Dr. Reneì Dubos], Carol L. Moberg
Friend Of The Good Earth: [Dr. Reneì Dubos], Carol L. Moberg
Rockefeller University Research Profiles
Rockefeller University Research Profiles are a series of scientific profiles that were published quarterly, from 1980-1990, by the Rockefeller University. Each issue features the research and achievements of an individual Rockefeller University scientist.
Brainwork: [Dr. Donald W. Pfaff], Fulvio Bardossi
Brainwork: [Dr. Donald W. Pfaff], Fulvio Bardossi
Rockefeller University Research Profiles
Rockefeller University Research Profiles are a series of scientific profiles that were published quarterly, from 1980-1990, by the Rockefeller University. Each issue features the research and achievements of an individual Rockefeller University scientist.
Identification, Characterization, And Developmental Analyses Of A Growth Cone Specific Epitope And A Synaptic Vesicle Protein, Stephen Henri Devoto
Identification, Characterization, And Developmental Analyses Of A Growth Cone Specific Epitope And A Synaptic Vesicle Protein, Stephen Henri Devoto
Student Theses and Dissertations
This thesis describes a growth cone specific epitope (CD'A 1), a synaptic vesicle antigen (SVP38), and the developmental expression of each in various tissues. Although CD' A 1 and SVP38 do not have any direct relationship to each other, I will show that the expression of both changes over the same time period. This provides a unifying theme for my work. I have therefore decided not to divide my thesis into independent sections, each with its own introduction, results, and discussion, but rather attempt to tie all of my work together into a single unit. The thesis is divided into …
Fast Sound Propagation In Binary Fluid Mixtures, Alessandro Campa
Fast Sound Propagation In Binary Fluid Mixtures, Alessandro Campa
Student Theses and Dissertations
In this thesis I am concerned with the dynamical properties, at the molecular level, of binary fluid mixtures in equilibrium; binary fluid mixtures are fluids consisting of two different components. As for simple (one component) fluids, the main experimental probes for the study of these properties of binary mixtures are light and neutron scattering. To connect the dynamics with scattering experiments one can use the kinetic theory of fluids. I have applied the kinetic theory to binary mixtures where the atomic masses of the molecules of the two components are very different (disparate-mass binary mixtures). I have studied both dilute …
Studies On The Activity Of The Long Terminal Repeat Of Rous Sarcoma Virus In Animal Cells And In Yeast, Anindya Dutta
Studies On The Activity Of The Long Terminal Repeat Of Rous Sarcoma Virus In Animal Cells And In Yeast, Anindya Dutta
Student Theses and Dissertations
Transcription from the Rous sarcoma virus (RSV) Long terminal repeat (LTR) in untransformed rat 3Yl fibroblasts is dependent on the presence of serum. Within an hour of addition of serum to a serum-deprived culture there is a 5 fold stimulation in the level of transcripts initiated at the LTR. This stimulation does not require synthesis of new proteins. Mutations in the RSV LTR revealed that serum-stimulated transcription was mostly dependent on two CCAAT boxes in the LTR, though other upstream sequences may play a secondary role. Serum caused the rapid appearance of a nuclear protein that binds to the two …
Molecular Cloning Of Avian Sarcoma Virus Ct10 And Characterization Of Its Protein Product, Bruce J. Mayer
Molecular Cloning Of Avian Sarcoma Virus Ct10 And Characterization Of Its Protein Product, Bruce J. Mayer
Student Theses and Dissertations
Four previously uncharacterized avian sarcoma viruses were screened and two of these, RPL30 and CTIO, were found to encode apparently novel oncogenes. Biologically active CTIO DNA was molecularly cloned and the nucleotide sequence was determined. The CTIO genome encodes a gag-fusion polypeptide of 47 kilodaltons, termed p47gag-crk. This protein contains blocks of sequence similarity to a noncatalytic, potentially regulatory region found in the nonreceptor tyrosine kinases, a phosphoinositide-specific phospholipase C, and the ras GTPase activator protein; no homology was found to any known catalytic domain. Potential roles for the homologous domains, termed SH2 and SH3, in normal signal …
On The Repair Of Dna Breaks And The Specificity Of The Ecori Restriction Enzyme, Joseph Heitman
On The Repair Of Dna Breaks And The Specificity Of The Ecori Restriction Enzyme, Joseph Heitman
Student Theses and Dissertations
We would like to understand how proteins and enzymes interact with DNA. We describe here our studies of the Mrr methylation dependent restriction system, DNA single- and double-strand break repair in E. coli, and substrate recognition by the EcoRI endonuclease. Many species of bacteria make restriction-modification systems to destroy foreign DNA that enters the cell. These systems usually consist of an endonuclease that cleaves a specific DNA sequence and a methylase which modifies the DNA to protect the host chromosome. We observed that when foreign site-specific methylases are expressed in E. coli, the SOS DNA repair response is induced. This …
Dna-Protein Interactions In F1 Dna Replication, David I. Greenstein
Dna-Protein Interactions In F1 Dna Replication, David I. Greenstein
Student Theses and Dissertations
This thesis analyzes the interaction of two DNA-binding proteins with the plus strand replication origin of bacteriophage f1. The origin has a bipartite structure consisting of a required core origin region and an adjacent A +T- rich enhancer sequence that potentiates replication approximately 100-fold. The core origin binds the initiator protein, and the enhancer contains three binding sites for the E. coli integration host factor (IHF). Both activator proteins bend the DNA sequence to which they bind, implying that together they wrap the origin DNA into a higher order structure that is active in initiation. The replication initiator protein of …
Genespeak: [Dr. Michael W. Young], None None
Genespeak: [Dr. Michael W. Young], None None
Rockefeller University Research Profiles
Rockefeller University Research Profiles are a series of scientific profiles that were published quarterly, from 1980-1990, by the Rockefeller University. Each issue features the research and achievements of an individual Rockefeller University scientist.